scholarly journals KADAR b-hCG PENDERITA MOLA HIDATIDOSA SEBELUM DAN SESUDAH KURETASE

2018 ◽  
Vol 13 (1) ◽  
pp. 1
Author(s):  
Syafii . ◽  
S Aprianti ◽  
Hardjoeno .
Keyword(s):  
Risk Factors ◽  
Retrospective Study ◽  
Public Hospital ◽  
High Incidence ◽  
Before And After ◽  
Important Disease ◽  
Trophoblastic Tumours

Hydatiform mole is an important disease, with a high incidence, many risk factors, and equity spreading. To know and compareb-hCG levels among patients with hydatiform mole before and after curretage was investigated. A retrospective study from January2002 to December 2005 at Dr. Wahidin Sudirohusodo Public Hospital was performed comprising b-hCG levels of hydatiform molepatients before and after curettage. b-hCG level (Elisa’s method) were grouped by age of pregnancy. Among 72 patients, 43 patients withhydatiform mole were found. At trimester I among 10 patients (23.3%), b-hCG level was higher 3 (7.0%), normally 4 (9.3%) and lower3 (7.0%). At trimester II, among 33 patients (76.7%), b-hCG level was higher 12 (27.9%), normal 13 (30.2%) and lower 3 (7.0%).After curretage, b-hCG level was decreased in 35 (81.4%), and increased in 7 (16.3%). Diagnosis of hydatiform mole was establishedin 36 (83.7%) and Gestational Trophoblastic Tumours (GTT) 7 (16.3%). Patients with hydatiform mole had the highest incidence intrimester II with normal b-hCG level and b-hCG level decreased after curretage.

scholarly journals Risk factors for medication errors in the electronic and manual prescription

2016 ◽  
Vol 24 (0) ◽  
Author(s):  
Cris Renata Grou Volpe ◽  
Eveline Maria Magalhães de Melo ◽  
Lucas Barbosa de Aguiar ◽  
Diana Lúcia Moura Pinho ◽  
Marina Morato Stival
Keyword(s):  
Risk Factors ◽  
Retrospective Study ◽  
Medication Errors ◽  
Medical Records ◽  
Public Hospital ◽  
Study Data ◽  
Electronic Records ◽  
Brand Name ◽  
Electronic Prescription ◽  
Medication Process

ABSTRACT Objective: to compare electronic and manual prescriptions of a public hospital of Brasilia, identifying risk factors for the occurrence of medication errors. Method: descriptive-exploratory, comparative and retrospective study. Data collection occurred from July 2012 to January 2013, using an instrument for the review of the information contained in medical records related to the medication process. A total of 190 manual and 199 electronic records composed the sample, with 2027 prescriptions each. Results: compared to the manual prescription, a significant reduction was observed in the risk factors after implantation of the electronic prescription, in items such as "lack of the form of dilution" (71.1% to 22.3%) and "prescription with brand name" (99.5% to 31.5%). Conversely, the risk factors "no check" and "lack of CRM of the prescriber" increased. The lack of the allergy registration and the occurrences related to medication were the same for both groups. Conclusion: generally, the use of the electronic prescription system was associated with a significant reduction in risk factors for medication errors, concerning the following aspects: illegibility, prescription with brand name and presence of essential items that provide a safe and effective prescription.

scholarly journals Risk factors for severe gastrointestinal toxicity in patients receiving palliative radiotherapy for metastatic bone tumors: association with the use of molecular-targeted agents

2020 ◽  
Vol 61 (4) ◽  
pp. 629-634
Author(s):  
Yuji Murakami ◽  
Masahiro Kenjo ◽  
Kazuki Ishikawa ◽  
Toru Sakayauchi ◽  
Satoshi Itasaka ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bone Tumors ◽  
Significant Risk ◽  
Palliative Radiotherapy ◽  
Targeted Agents ◽  
High Incidence ◽  
Before And After ◽  
History Of ◽  
Gi Toxicity ◽  
Molecular Targeted Agents

Abstract This study aimed to investigate whether the use of molecular-targeted agents could affect gastrointestinal (GI) toxicity in palliative radiotherapy (RT) for metastatic bone tumors in the abdominopelvic region. We collected data of patients who received palliative RT for bone metastases in the abdominopelvic region between 2013 and 2014 from six institutions. Data of 395 patients were collected and184 patients received molecularly targeted therapy, of whom 80 received vascular endothelial growth factor (VEGF)-targeted agents. For 556 lesions, 410 sessions of irradiation were undergone. GI toxicity of ≥G3 was observed in 3.8% of patients. The incidence rates of ≥G3 GI toxicity in patients without targeted agents use, in those using VEGF-targeted agents and in those using non-VEGF-targeted agents were 3.8, 7.5 and 1.0%, respectively. Regarding risk factors of the occurrence of ≥G3 GI toxicity, univariate analysis in all patients showed that a history of abdominopelvic surgery was a significant risk factor (P = 0.01), and the use of VEGF-targeted agents showed a trend of high incidence (P = 0.06). In patients using VEGF-targeted agents, both univariate and multivariate analysis showed that combined anticoagulant use (P = 0.03 and 0.01) and agent use between 1 week before and after RT (P = 0.046 and 0.03) were significant risk factors. In conclusion, the history of abdominopelvic surgery was associated with ≥G3 GI toxicity and the use of VEGF-targeted agents showed a trend for high incidence. When using VEGF-targeted agents, caution should be exercised in the combined use of anticoagulants and in the agent use between 1 week before and after RT.

scholarly journals FAKTOR-FAKTOR YANG MEMPENGARUHI LUARAN PENANGANAN ATRESIA ESOPHAGUS

2017 ◽  
Vol 17 (2) ◽  
pp. 71-74
Author(s):  
Dian Adi Syahputra ◽  
Bustanul Arifin Nawas ◽  
Dikki Drajat Kusmayadi
Keyword(s):  
Risk Factors ◽  
Congenital Anomaly ◽  
Congenital Heart Disease ◽  
Retrospective Study ◽  
Birth Weight ◽  
Esophageal Atresia ◽  
Congenital Heart ◽  
Definitive Treatment ◽  
Exact Probability ◽  
Before And After

Abstrak. Atresia esofagus merupakan bentuk kelainan kongenital yang memiliki tingkat mortalitas tinggi berkaitan dengan berbagai komplikasi yang dapat muncul sebelum dan sesudah tindakan operasi definitif. Penelitian ini bertujuan untuk mengetahui faktor – faktor yang mempengaruhi luaran penanganan atresia esofagus. Penelitian ini adalah penelitian analitik retrospektif dari data yang terdapat pada rekam medis pada tahun Januari 2002 hingga Agustus 2009 dari 2 rumah sakit di Bandung, Jawa Barat. Uji Fisher's Exact Probability Test dan Kruskal Walis digunakan untuk menilai luaran masing – masing kelompok. Pada penelitian ini terdapat 26 penderita (13 laki – laki dan 13 perempuan). Rentang usia saat penderita datang ke rumah sakit yaitu 3 ± 1,41 hari. Berat badan lahir rata - rata adalah 2.475 ± 35,35 gram. Pada penelitian ini terdapat hubungan yang signifikan antara keadaan sepsis pra operasi (p= 0.032) dan lama penggunaan ventilator (p= 0.022) dengan luaran penderita atresia esofagus. Sementara tidak terdapat hubungan yang signifikan antara berat badan lahir (p= 0.11), kehadiran pneumonia (p=0.11) , kehadiran kelainan jantung bawaan (p= 0.99) dan jenis ruang rawatan (p= 0.683) terhadap luaran penderita atresia esophagus. (JKS 2017; 2: 72-76)  Kata Kunci: atresia esophagus, faktorresiko, luaran Abstract. Esophageal atresia is a congenital anomaly that have high mortality rate associated with complication appears before and after definitive treatment. Analytic retrospective study to identified risk factors that influence outcome of esophageal atresia. Data were reviewed from medical record of patients with esophageal atresia within January 2002 to August 2009 that hospitalized in 2 hospitals in Bandung, West Java. Fisher's Exact Probability and Kruskal Walis Test were used for the statistical analysis. There are 26 patients (13 boys and 13 girls) with average age when the patients came to hospital is 3 ± 1,41 days old. Mean birth weight among all patients is 2.475 ± 35,35 grams. In this study, sepsis condition before operation and lenght of using ventilator are significant to outcome with (p= 0.032) and (p= 0.022). While birth weight, pneumonia, congenital heart disease, ward during treatment were not significant with (p= 0.11), (p=0.11), (p= 0.99), and (p= 0.683). (JKS 2017; 2: 72-76)  Keywords : esophageal atresia, risk factors, outcome

scholarly journals Combination Antiretroviral Therapy is Associated with Reduction in Liver Fibrosis Scores in Patients with HIV and HBV Co-Infection

2021 ◽  
Author(s):  
Rongrong Yang ◽  
Xien Gui ◽  
Hengning Ke ◽  
Yong Xiong ◽  
Shicheng Gao
Keyword(s):  
Risk Factors ◽  
Retrospective Study ◽  
Antiretroviral Therapy ◽  
Liver Fibrosis ◽  
Cox Regression ◽  
Wilcoxon Test ◽  
Combination Antiretroviral Therapy ◽  
Paired Samples ◽  
Before And After ◽  
Group 1

Abstract Objective To evaluate the risk factors for liver fibrosis in HIV/HBV co-infection population, and further to clarify whether ART reverses fibrogenic effect of HIV infection. Methods This was an observational retrospective study. Multivariate Cox regression was used to assess predictors of liver fibrosis in HIV/HBV co-infection patients. FIB-4 scores before and after cART were compared using Wilcoxon test for paired samples. Results In this study enrolled 458 cases of HIV/HBV co-infection patients, we found ART (HR 0.016, 95% CI: 0.009-0.136; P<0.001) were one of protection factors to against liver fibrosis. Forty cases of those who had normal levels of ALT, AST and PLT during the whole course of diseases were stratified into FIB-4<1.45 (n=14), 1.45≤FIB-4 ≤3.25 (n=19) and FIB-4>3.25 (n=7) groups by their FIB-4 scores before ART. After ART, in 1.45≤FIB-4≤3.25 group, FIB-4 grade in 57.9%(11/19) of the patients dropped to a lower FIB-4 grade (FIB-4<1.45); in FIB-4>3.25 group, 85.7%(6/79) of the patients dropped to 1.45≤FIB-4≤3.25 grade, while 14.3%(1/7) dropped to FIB-4<1.45 grade. In ART-naive group, 1 year, 2-5 years and 5-10 years after ART groups, FIB-4 scores were 4.29±0.43, 3.63±0.38, 2.90±0.36 and 2.52±0.38, respectively (P=0.034); and the incidence of liver fibrosis were 7.38%(104/141), 63.6%(98/154), 60.8%(62/102) and 47.5%(29/61), respectively (P=0.004). Conclusion ART was associated with improvement of FIB-4 scores and the benefit of ART in reversing liver fibrosis can sustain for a decade in patients with HIV/HBV co-infection.

Diagnostic scales for suicide risk assessment

2020 ◽  
pp. 67-79
Author(s):  
L. Gelda ◽  
L. Nesterovich
Keyword(s):  
Risk Factors ◽  
Risk Assessment ◽  
Medical Research ◽  
Suicide Risk ◽  
General Medicine ◽  
Diagnostic Tools ◽  
Suicide Risk Assessment ◽  
Research And Practice ◽  
Psychometric Instruments ◽  
High Incidence

The problem of adequate diagnostic tools use for suicide risk assessment т medical research and practice is of extreme importance because of the high incidence of suicide in the population of psychotic patients and the high vulnerability of the latter to the known risk factors. The article provides ап overview of the existing psychometric instruments (scales) used to assess the risk of suicide in psychiatry as well as in general medicine.

RISK FACTORS FOR THE DEVELOPMENT OF INITIAL MANIFESTATIONS OF ATHEROGENIC CARDIOVASCULAR DISEASES IN PERSONNEL OF CHEMICALLY HAZARDOUS FACILITIES

2017 ◽  
pp. 2-7 ◽  
Author(s):  
V. A. Gorichny ◽  
D. Yu. Serdukov ◽  
A. V. Yazenok ◽  
A. V. Nosov ◽  
G. G. Zagorodnikov ◽  
...  
Keyword(s):  
Risk Factors ◽  
Statistical Analysis ◽  
Cardiovascular Diseases ◽  
Organophosphorus Compounds ◽  
Atherogenic Dyslipidemia ◽  
Chemical Weapons ◽  
Analysis Methods ◽  
High Incidence ◽  
And Control ◽  
Statistical Analysis Methods

An outpatient examination of 530 employees engaged in work with chemical weapons related to organophosphorus compounds at chemically hazardous facilities was carried out. Risk factors for the development of cardiovascular diseases of atherogenic etiology among personnel of the facilities were studied in relation to the type of work performed using statistical analysis methods. When assessing the lipidogram, a high incidence of atherogenic dyslipidemia in a group of personnel involved in the storage of chemical weapons was found out in comparison with a group of people engaged in the destruction and control of chemical weapons (73.1 vs 61.2 vs 59.6%, p

Prevalence of anaemia and it's associated risk factors among under five children at Mukinge Missions Hospital in Kasempa District: Retrospective Study (Preprint)

2019 ◽  
Author(s):  
Lloyd Sampa
Keyword(s):  
Risk Factors ◽  
Retrospective Study ◽  
Mean Corpuscular Volume ◽  
Sub Saharan Africa ◽  
Corpuscular Volume ◽  
Under Five ◽  
Under Five Children ◽  
Mission Hospital ◽  
Associated Risk Factors ◽  
Prevalence Of Anemia

BACKGROUND Anemia is a worldwide major problem known to affect people throughout the world. It has an adverse effect on both the social and economic development. The worldwide prevalence of anemia is 9% in developed nations. The global estimate indicates that 293.1 million of children under five years, approximately 43%, are anaemic worldwide and 28.5% of these children are found in sub Saharan Africa. In Zambia specifically Kasempa, no documented studies on prevalence have been done. Despite iron supplementation being given to pregnant women and the availability of blood transfusion. The burden of the disease remains high as determined by high mortality and morbidity. This study aims at determining the prevalence of anemia and the associated risk factors among under-five children at Mukinge Mission Hospital in Kasempa District. Knowledge of prevalence and the associated risk factors of anaemia will enhance early detection and timely management. OBJECTIVE 1.To determine the hemoglobin status of anaemia by its severity among anaemic under-five children admitted at Mukinge Mission Hospital. 2.To assess the association of anaemia with Malaria among under-five children admitted at Mukinge Mission Hospital. METHODS This was a retrospective study review of under-five children that were diagnosed and managed of Anemia at Mukinge Missions Hospital, over the period of period of 2015, 2017 and 2018. .Data of the variables of interest was extracted and analyzed using SPSS. RESULTS A sample population of 52 children was included in our study. The majority of the children were females 28 (53.8 %) and 24 (46.2 %) were Males. It was found that moderate and severe anaemia was 17.3% and 82.7 % respectively. Additionally, Majority of the anaemic children (75%) had Normocytic anaemia. The Pearson Chi square test revealed no statistical relationship between the variables; Malaria (p=0.58), Age (P=0.82), Gender (P=0.91). CONCLUSIONS According to our study, 39 (75%) had normal mean corpuscular volume which could suggest chronic diseases and sickle cell anemia. 11 (21.2%) had a low mean corpuscular volume indicating Microcytic anemia which could suggest diseases such as iron deficiency and thalassemia among many other causes. However, we were unable to determine the specific cause of anemia.

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