Colorimetric Determination of Fluoride in Drinking Groundwater using a Polymeric Zirconium Complex of 5-(2-Carboxyphenylazo)-8-Hydroxyquinoline

A sensitive colorimetric determination of fluoride in drinking water has been developed using a polymeric zirconium complex of 5-(2-Carboxyphenylazo)-8-Hydroxyquinoline as fluoride reagents. The method allowed a reliable determination of fluoride in range of (0.0-1.5) mg L-1. The molar absorptivity of the complex formation is 7695 ± 27 L mol-1 cm-1 at 460 nm. The sensitivity, detection limit, quantitation limit, and percentage recovery for 1.0 mg L-1 fluoride for the proposed method were found to be 0.353 ± 0.013 μg mL-1, 0.1 mg L-1, 0.3 mg L-1, and 101.7 ± 4.1, respectively.

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Spectrophotometric Determination of Fluoride in Groundwater Using Complexes of Flavonoid Chrysin

مجلة جامعة فلسطين التقنية للأبحاث ◽

10.53671/pturj.v1i1.8 ◽

2013 ◽

Vol 1 (1) ◽

pp. 16-20

Author(s):

Zaher Barghouthi ◽

Sameer Amereih ◽

Saed Khayat

Keyword(s):

Drinking Water ◽

Detection Limit ◽

Visible Region ◽

Free Ligand ◽

Molar Absorptivity ◽

Reliable Determination ◽

Limit Value ◽

Quantitation Limit ◽

Colour Changes

A simple spectrophotometric method is developed for determination of fluoride in drinking water by using complexes of chrysin. The method is based on the reaction of the coloured complexes with fluoride where its colour changes, due to the formation of the colourless fluoride complex and liberating of the free ligand, is dependent on the concentration of fluoride in water samples. The molar absorptivity for the complexes at the wavelength of maximum absorption in the visible region, 371 nm is 2.75 × 103 L mol-1 cm-1. The method allows a reliable determination of fluoride in the range 0.3─3.0 mg L-1 which is compatible to WHO limit value of 1.5 mg L-1. The sensitivity, detection limit, quantitation limit, and correlation coefficient for the method were found to be 0.211 μg mL-1, 0.1 mg L-1, 0.3 mg L-1, and 0.9914 respectively. The percentage recovery of 1.5 mg L-1 fluoride is 101.3.

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Spectrophotometric Determination of Fluoride in Groundwater Using Complexes of Flavonoid Chrysin

مجلة جامعة فلسطين التقنية للأبحاث ◽

10.53671/ptukrj.v1i1.8 ◽

2013 ◽

Vol 1 (1) ◽

pp. 16-20

Author(s):

Zaher Barghouthi ◽

Sameer Amereih ◽

Saed Khayat

Keyword(s):

Drinking Water ◽

Detection Limit ◽

Visible Region ◽

Free Ligand ◽

Molar Absorptivity ◽

Reliable Determination ◽

Limit Value ◽

Quantitation Limit ◽

Colour Changes

A simple spectrophotometric method is developed for determination of fluoride in drinking water by using complexes of chrysin. The method is based on the reaction of the coloured complexes with fluoride where its colour changes, due to the formation of the colourless fluoride complex and liberating of the free ligand, is dependent on the concentration of fluoride in water samples. The molar absorptivity for the complexes at the wavelength of maximum absorption in the visible region, 371 nm is 2.75 × 103 L mol-1 cm-1. The method allows a reliable determination of fluoride in the range 0.3─3.0 mg L-1 which is compatible to WHO limit value of 1.5 mg L-1. The sensitivity, detection limit, quantitation limit, and correlation coefficient for the method were found to be 0.211 μg mL-1, 0.1 mg L-1, 0.3 mg L-1, and 0.9914 respectively. The percentage recovery of 1.5 mg L-1 fluoride is 101.3.

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Spectrophotometric Determination of Palladium(II) Ions Using a New Reagent: 4-(N’-(4-Imino-2-oxo-thiazolidine-5-ylidene)-hydrazino)-benzoic Acid (p-ITYBA)

Journal of Chemistry ◽

10.1155/2020/8141853 ◽

2020 ◽

Vol 2020 ◽

pp. 1-8 ◽

Cited By ~ 1

Author(s):

Oleksandr S. Tymoshuk ◽

Orest S. Fedyshyn ◽

Lesia V. Oleksiv ◽

Petro V. Rydchuk ◽

Vasyl S. Matiychuk

Keyword(s):

Detection Limit ◽

Complex Formation ◽

Benzoic Acid ◽

Spectrophotometric Determination ◽

Spectrophotometric Method ◽

Molar Absorptivity ◽

Water Medium ◽

Analytical Reagent ◽

Optimal Ph

The simple, rapid spectrophotometric method for palladium(II) ions determination using a new analytical reagent is described. The interaction of Pd(II) ions with a reagent, of the class of azolidones, 4-(N′-(4-imino-2-oxo-thiazolidine-5-ylidene)-hydrazino)-benzoic acid, in water medium results in the formation of a complex. The Pd(II)-p-ITYBA complex shows maximum absorbance at a wavelength of 450 nm. The molar absorptivity is 4.30 × 103 L·mol−1·cm−1. The optimal pH for complex formation is 7.0. The developed method has a wide linearity range of 0.64–10.64 µg·mL−1 for Pd(II). The detection limit is 0.23 µg·mL−1. It was found that Co(II), Ni(II), Zn(II), Fe(III), Cu(II), Al(III), and many anions do not interfere with the Pd(II) determination. The proposed method was tested in the analysis of model solutions and successfully applied for the determination of palladium in catalyst. The obtained results show that this method can be used for serial determinations of palladium in various objects.

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SPECTROPHOTOMETRIC DETERMINATION OF NEVIRAPINE USING TETRATHIOCYANATOCOBALT(II) ION AS A REAGENT

Eclética Química Journal ◽

10.26850/1678-4618eqj.v35.3.2010.p93-102 ◽

2018 ◽

Vol 35 (3) ◽

pp. 93

Author(s):

T. V. Badiadka ◽

Badiadka Narayana

Keyword(s):

Detection Limit ◽

Spectrophotometric Determination ◽

Spectrophotometric Method ◽

Statistical Evaluation ◽

Pharmaceutical Formulations ◽

Molar Absorptivity ◽

Optical Parameters ◽

Quantitation Limit ◽

Optimum Reaction

A simple and rapid spectrophotometric method for the determination of nevirapine is described. The method is based on the reaction of nevirapine with tetrathiocyanatocobalt(II) ion in buffer of pH 4 to form the corresponding complex. Beer’s law is obeyed in the range of 0.2 – 2.0 μg mL-1 for nevirapine. The optical parameters such as molar absorptivity, Sandell’s sensitivity, detection limit and quantitation limit were found to be 1.16× 104 Lmol-1cm-1, 2.09 X 10-3 μg cm-2, 0.073 μg mL-1 and 0.222 μg mL-1 respectively. The optimum reaction conditionsand other analytical parameters were evaluated. The statistical evaluation of the method was examined by determining intra-day and inter-day precision. The proposed method has been successfully applied for the determination of nevirapine in pharmaceutical formulations.

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Spectrophotometric determination of nicradipine and isradipine in pharmaceutical formulations

Chemical Industry and Chemical Engineering Quarterly ◽

10.2298/ciceq0902069a ◽

2009 ◽

Vol 15 (2) ◽

pp. 69-76 ◽

Cited By ~ 1

Author(s):

S.M. Al-Ghannam ◽

A.M. Al-Olyan

Keyword(s):

Standard Deviation ◽

Detection Limit ◽

Reaction Pathway ◽

Pharmaceutical Preparations ◽

Pharmaceutical Formulations ◽

Molar Absorptivity ◽

Zinc Powder ◽

Conditional Stability ◽

Conditional Stability Constant

A sensitive spectrophotometric method was developed for the determination of some 1,4-dihydropyridine compounds namely, nicardipine and isradipine either in pure form or in pharmaceutical preparations. The method is based on the reduction of nicardipine and isradipine with zinc powder and calcium chloride followed by further reduction with sodium pentacyanoaminoferrate (II) to give violet and red products having the absorbance maximum at 546 and 539 nm with nicardipine and isradipine, respectively. Beer's law was obeyed over the concentration range 8.0-180 ?g/ml with the detection limit of 1.67 ?g/ml for nicardipine and 8.0-110 ?g/ml with the detection limit of 1.748 ?g/ml for isradipine. The analytical parameters and their effects on the reported methods were investigated. The molar absorptivity, quantization limit, standard deviation of intercept (Sa), standard deviation of slope (Sb) and standard deviation of the residuals (Sy/x) were calculated. The composition of the result compounds were found 1:1 for nicardipine and 1:2 for isradipine by Job's method and the conditional stability constant (Kf) and the free energy changes (?G) were calculated for compounds formed. The proposed method was applied successfully for the determination of nicardipine and isradipine in their dosage forms. The results obtained were in good agreement with those obtained using the reference or official methods. A proposal of the reaction pathway was presented.

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Spectrophotometric determination of metoclopramide hydrochloride in pharmaceutical tablets, by diazotization-coupling method with 1-naphthol as the coupling agent

Baghdad Science Journal ◽

10.21123/bsj.7.1.704-712 ◽

2010 ◽

Vol 7 (1) ◽

pp. 704-712

Author(s):

Baghdad Science Journal

Keyword(s):

Detection Limit ◽

Azo Dye ◽

Diazonium Salt ◽

Molar Absorptivity ◽

British Pharmacopoeia ◽

Pharmaceutical Tablets ◽

Hydrochloric Acid Medium ◽

Metoclopramide Hydrochloride ◽

Sensitive Spectrophotometric Method

Simple, rapid and sensitive spectrophotometric method was proposed for the analysis of metoclopramide hydrochloride (MPH) in pure form as well as in pharmaceutical tablets. The method is based on the diazotization reaction of MPH with sodium nitrite in hydrochloric acid medium to form diazonium salt, which is coupled with 1-naphthol in sodium hydroxide medium to form azo dye, showing absorption maxima at 550 nm. Beer’s law is obeyed in the concentration range of 0.4 – 18 µg mL-1 of MPH with detection limit 0.5448 µg mL-1. The molar absorptivity and Sandell’s sensitivity are 3.4969 × 104 L mol-1 cm-1 and 0.0101 µg cm-2, respectively. The method was successfully applied to the determination of MPH in pharmaceutical tablets without any interference from common excipients used as additives in tablets. The results agree favorably with the official British Pharmacopoeia method.

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Colorimetric Determination of Certain Phenothiazine Drugs by Using Morpholine and Iodine-Potassium Iodide Reagents

Journal of AOAC INTERNATIONAL ◽

10.1093/jaoac/69.3.513 ◽

1986 ◽

Vol 69 (3) ◽

pp. 513-518 ◽

Cited By ~ 1

Author(s):

Adel F Youssef ◽

Salwa R El-Shabouri ◽

Fardous A Mohamed ◽

Abdel Maboud I Rageh

Keyword(s):

Potassium Iodide ◽

Quantitative Estimation ◽

Colorimetric Method ◽

Molar Absorptivity ◽

Dosage Forms ◽

Colorimetric Determination ◽

Reaction Products ◽

Phenothiazine Drugs ◽

Lower Molar

Abstract A colorimetric method was developed for the quantitative estimation of 11 phenothiazine drugs. The method is based on the interaction of unsulfoxidized drug with morpholine and iodine-potassium iodide reagents. The interaction for all studied phenothiazine drugs yields a blue product with 2 absorption maxima: one in the range of 620-640 nm with lower molar absorptivity and the other in the range of 662-690 nm with higher molar absorptivity. The color was stable for at least 10 h. The reproducibility and recovery of the method were excellent. The method was applied successfully to the analysis of various commercially available phenothiazines in different dosage forms. The results were comparable to those obtained by official procedures. The suitability of the method for detection and estimation of promethazine excreted in urine has been suggested by preliminary experiments. Reaction products have been isolated and identified.

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Spectrophotometric determination of Uranium through complex formation with roxarsone

Mediterranean Journal of Chemistry ◽

10.13171/mjc106020071479nmmaa ◽

2020 ◽

Vol 10 (6) ◽

pp. 634

Author(s):

Nashat Mohamed Alanwar Abd alaty

Keyword(s):

Complex Formation ◽

Inductively Coupled Plasma ◽

Rapid Determination ◽

Molar Absorptivity ◽

Pure Form ◽

Metallic Ions ◽

Font Size ◽

Uranium Ore ◽

Inductively Coupled

A new sensitive, accurate, and non-extractive spectrophotometric method was developed for the rapid determination of Uranium in pure form and Uranium ore using roxarsone. The procedure was based on the complex formation between Uranium (VI) and roxarsone. This showed maximum absorption at λmax 395 nm with a linear relationship in the concentration range from (20-100 µg mLˉ¹) with a molar absorptivity 9.57×103(1mol-1 cm-1). Inductively Coupled Plasma mass spectroscopy (ICP-MS) was used in the study of the interferences caused by some metallic ions, which were effectively masked by tartaric acid and diethylenetriaminepenta-acetic acid (DTPA). The method holds its accuracy and precision well when applied to the determination of the studied Uranium in its pure form and Uranium ore.

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A novel sensitive colorimetric determination of catecholamine drug in dosage form via oxidative coupling reaction with MBTH and potassium ferricyanide

Drug Analytical Research ◽

10.22456/2527-2616.113058 ◽

2021 ◽

Vol 5 (1) ◽

pp. 51-58

Author(s):

Safwan Ashour

Keyword(s):

Oxidative Coupling ◽

Colorimetric Method ◽

Standard Free Energy ◽

Coupling Reaction ◽

Pharmaceutical Formulations ◽

Molar Absorptivity ◽

Potassium Ferricyanide ◽

Colorimetric Determination ◽

Oxidative Coupling Reaction

A new and direct colorimetric method has been established for the determination of catecholamine (methyldopa, MD) in both pure form and in pharmaceutical formulations. The method is based on the oxidative coupling reaction of MD with 3-methyl-2-benzothiazolinone hydrazone hydrochloride monohydrate (MBTH) and potassium ferricyanide at pH 10.4 in aqueous medium to form an orange product that has a maximum absorption at 460 nm. Beer's law plot showed good correlation in the concentration range of 1.0−56.0 µg mL-1, with detection limit of 0.31 µg mL-1. Molar absorptivity for the above method was found to be 6.56×103 L mol-1 cm-1. All the measurements were carried out at 25 ± 1.0 °C, the formation constant (logKf) value of colored species is 9.48 and the standard free energy (DG‡) is − 54.09 KJ mol-1. This method was applied successfully to determination of MD in tablets and the results were compared with the USP method. Common excipients used as additives in tablets do not interfere in the proposed method. The method is accurate, precise and highly reproducible, while being simple, cheap and less time consuming and hence can be suitably applied for routine analysis of MD in bulk and dosage forms.

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