scholarly journals The use of electroencephalography in patients with sepsis: A review of the literature

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Nikolaos-Dimitrios Pantzaris ◽  
Christina Platanaki ◽  
Konstantinos Tsiotsios ◽  
Ioanna Koniari ◽  
Dimitrios Velissaris
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Low Cost ◽  
Neurological Status ◽  
Neurological Complications ◽  
Brain Dysfunction ◽  
Review Of The Literature ◽  
Specific Test ◽  
Diagnosis And Prognosis ◽  
The Central Nervous System

AbstractSepsis-associated encephalopathy (SAE) is the term used to define brain dysfunction related to infections that are principally located outside the central nervous system (CNS). A number of published studies report that electroencephalography (EEG) has been used in the evaluation of patients with sepsis, alone or usually in combination, to evoked potentials and neuroimaging. This was in an effort to assess if EEG can be a tool in the diagnosis and monitoring of the neurological status in sepsis patients. Although there is no specific test for the diagnosis and prognosis of sepsis related encephalopathy, our literature review suggests that EEG has a role in the assessment of this clinical entity. Due to its low cost and simplicity in its performance, EEG could be a potential aid in the assessment of sepsis neurological complications even in the early, subclinical stages of the syndrome. The aim of this review is to summarize the published literature regarding the application and utility of electroencephalography in adult patients with sepsis.

Assessment of Biochemical Markers of Perinatal Injuries of Central Nervous System in the Children

10.12737/4991 ◽  
2014 ◽  
Vol 21 (2) ◽  
pp. 26-29 ◽  
Author(s):  
Зуйкова ◽  
A. Zuykova ◽  
Балакирева ◽  
E. Balakireva ◽  
Красноруцкая ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Biochemical Markers ◽  
Perinatal Care ◽  
S100 Protein ◽  
Neurological Status ◽  
Brain Dysfunction ◽  
Modern Medicine ◽  
Early Age ◽  
The Central Nervous System

Pathology of the central nervous system in children of early age, due mainly hypoxic-ischemic brain damage in the antenatal period and delivery, which occupies a leading place among all factors of perinatal nervous system lesions in infants, is one of the most actual problems of modern medicine. Despite favourable demographic state, the improvement of the quality of perinatal care and medical care of newborns with a weight at birth from 500 grams, the tendency to reduction in the incidence of perinatal lesions of the central nervous system didn’t observed. On the contrary, there is progression of their course, which determines the subsequent mental and physical development of the child - from minimal brain dysfunction and gross motor and intellectual disorders, often resulting in disability. Purpose of the study is to evaluate the clinical features of central nervous system pathology in children of early age by means of neurobiochemistry markers and to develop prognostic criteria for the course and pathogenetic therapy regimens. Materials and methods. Comprehensive survey of 134 children (61 boys and 73 girls ) aged from 0 to 9 months was carried out with the assessment of neurological status and biochemical markers. Results of study. In formation of gravity of perinatal lesions all the studied markers participated, but to a greater extent – the parameters of neurotrophic lesions and endothelial dysfunction. The first component of the nervous tissue of the brain, responding to hypoxia, is microglial environment, which is caused by the growth of lesions S100- protein (i.e., the neuron at the stage of 0-1 months didn’t been metabolic changes – this is evidence of low levels of SOD and MDA).

scholarly journals Anti-programmed cell death-1 (PD-1) monoclonal antibodies involve reversible cranial dura matter

2021 ◽  
Vol 2021 (9) ◽  
Author(s):  
Hiroshi Kataoka ◽  
Daisuke Shimada ◽  
Hitoki Nanaura ◽  
Kazuma Sugie
Keyword(s):  
Central Nervous System ◽  
Cell Death ◽  
Nervous System ◽  
Monoclonal Antibodies ◽  
Programmed Cell Death ◽  
Adverse Effects ◽  
Neuromuscular Disorders ◽  
Neurological Complications ◽  
Programmed Cell Death 1 ◽  
The Central Nervous System

ABSTRACT This case is the first document to describe a patient receiving anti-programmed cell death 1 (PD-1) antibodies which showed cranial dura matter involvement. According to the increasing use of anti-PD-1 monoclonal antibodies, adverse effects can occur in several organs since its ligand PD-L1 and PD-L2 are expressed in a wide variety of tissues. The estimated rate of neurological complications is 1–4.2% of patients, and neuromuscular disorders are the most common. Adverse effects on the central nervous system including encephalitis are less frequent. Here, a patient receiving anti-PD-1 antibodies showed cranial dura matter involvement, and the dura enhancement on MRI was resolved by withdrawal of the treatment with anti-PD-1 antibodies only.

scholarly journals Progress in Research on SARS-CoV-2 Infection Causing Neurological Diseases and Its Infection Mechanism

2021 ◽  
Vol 11 ◽  
Author(s):  
Lintao Wang ◽  
Zhiguang Ren ◽  
Li Ma ◽  
Yanjie Han ◽  
Wenqiang Wei ◽  
...  
Keyword(s):  
Public Health ◽  
Central Nervous System ◽  
Nervous System ◽  
Neurological Diseases ◽  
Public Health Problem ◽  
Neurological Complications ◽  
Major Public Health Problem ◽  
The Central Nervous System ◽  
The Impact ◽  
Great Harm

COVID-19 has spread rapidly worldwide since its outbreak and has now become a major public health problem. More and more evidence indicates that SARS-CoV-2 may not only affect the respiratory system but also cause great harm to the central nervous system. Therefore, it is extremely important to explore in-depth the impact of SARS-CoV-2 infection on the nervous system. In this paper, the possible mechanisms of SARS-CoV-2 invading the central nervous system during COVID-19, and the neurological complications caused by SARS-CoV-2 infection were reviewed.

Solitary fibrous tumour of the central nervous system: pathological study of eight cases and review of the literature

Pathology ◽  
2009 ◽  
Vol 41 (7) ◽  
pp. 649-654 ◽  
Author(s):  
Amina Mekni ◽  
Jihene Kourda ◽  
Karim Ben Hammouda ◽  
Monia Tangour ◽  
Nidhameddine Kchir ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Solitary Fibrous Tumour ◽  
Review Of The Literature ◽  
Pathological Study ◽  
The Central Nervous System
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