scholarly journals Characterization of Slovenian coal and estimation of coal heating value based on proximate analysis using regression and artificial neural networks

2013 ◽  
Vol 11 (9) ◽  
pp. 1481-1491 ◽  
Author(s):  
Darja Kavšek ◽  
Adriána Bednárová ◽  
Miša Biro ◽  
Roman Kranvogl ◽  
Darinka Vončina ◽  
...  

AbstractAbstract Chemical composition of Slovenian coal has been characterised in terms of proximate and ultimate analyses and the relations among the chemical descriptors and the higher heating value (HHV) examined using correlation analysis and multivariate data analysis methods. The proximate analysis descriptors were used to predict HHV using multiple linear regression (MLR) and artificial neural network (ANN) methods. An attempt has been made to select the model with the optimal number of predictor variables. According to the adjusted multiple coefficient of determination in the MLR model, and alternatively, according to sensitivity analysis in ANN developing, two descriptors were evaluated by both methods as optimal predictors: fixed carbon and volatile matter. The performances of MLR and ANN when modelling HHV were comparable; the mean relative difference between the actual and calculated HHV values in the training data was 1.11% for MLR and 0.91% for ANN. The predictive ability of the models was evaluated by an external validation data set; the mean relative difference between the actual and predicted HHV values was 1.39% in MLR and 1.47% in ANN. Thus, the developed models could be appropriately used to calculate HHV. Graphical abstract

Author(s):  
Brian Bucci ◽  
Jeffrey Vipperman

Civilian noise complaints and damage claims have created the need for stations to monitor the production of military impulse noise. However, these stations suffer from numerous false positive detections (due to wind noise) of impulse events and often miss many events of interest. There is also interest in identifying specific noise sources, such different types of ordinance or different types of aircraft. To improve the accuracy of military impulse noise monitoring and make and initial effort to specifically classify noise source, an algorithm based upon an artificial neural network with inputs of conventional and custom acoustic metrics was proposed. To train and evaluate the noise classifier approximately 1,000 waveforms were field collected (110 military aircraft noise, 330 military impulse noise, and 560 non-impulse noise). The final noise classifier used kurtosis and crest factor and the custom metrics spectral slope and weighted square error as inputs. The classifier was able to achieve 99.7% accuracy on the training data set and 99.4% accuracy on the validation data set.


BMJ Open ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. e040778
Author(s):  
Vineet Kumar Kamal ◽  
Ravindra Mohan Pandey ◽  
Deepak Agrawal

ObjectiveTo develop and validate a simple risk scores chart to estimate the probability of poor outcomes in patients with severe head injury (HI).DesignRetrospective.SettingLevel-1, government-funded trauma centre, India.ParticipantsPatients with severe HI admitted to the neurosurgery intensive care unit during 19 May 2010–31 December 2011 (n=946) for the model development and further, data from same centre with same inclusion criteria from 1 January 2012 to 31 July 2012 (n=284) for the external validation of the model.Outcome(s)In-hospital mortality and unfavourable outcome at 6 months.ResultsA total of 39.5% and 70.7% had in-hospital mortality and unfavourable outcome, respectively, in the development data set. The multivariable logistic regression analysis of routinely collected admission characteristics revealed that for in-hospital mortality, age (51–60, >60 years), motor score (1, 2, 4), pupillary reactivity (none), presence of hypotension, basal cistern effaced, traumatic subarachnoid haemorrhage/intraventricular haematoma and for unfavourable outcome, age (41–50, 51–60, >60 years), motor score (1–4), pupillary reactivity (none, one), unequal limb movement, presence of hypotension were the independent predictors as its 95% confidence interval (CI) of odds ratio (OR)_did not contain one. The discriminative ability (area under the receiver operating characteristic curve (95% CI)) of the score chart for in-hospital mortality and 6 months outcome was excellent in the development data set (0.890 (0.867 to 912) and 0.894 (0.869 to 0.918), respectively), internal validation data set using bootstrap resampling method (0.889 (0.867 to 909) and 0.893 (0.867 to 0.915), respectively) and external validation data set (0.871 (0.825 to 916) and 0.887 (0.842 to 0.932), respectively). Calibration showed good agreement between observed outcome rates and predicted risks in development and external validation data set (p>0.05).ConclusionFor clinical decision making, we can use of these score charts in predicting outcomes in new patients with severe HI in India and similar settings.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Zhixiang Yu ◽  
Haiyan He ◽  
Yanan Chen ◽  
Qiuhe Ji ◽  
Min Sun

AbstractOvarian cancer (OV) is a common type of carcinoma in females. Many studies have reported that ferroptosis is associated with the prognosis of OV patients. However, the mechanism by which this occurs is not well understood. We utilized Genotype-Tissue Expression (GTEx) and The Cancer Genome Atlas (TCGA) to identify ferroptosis-related genes in OV. In the present study, we applied Cox regression analysis to select hub genes and used the least absolute shrinkage and selection operator to construct a prognosis prediction model with mRNA expression profiles and clinical data from TCGA. A series of analyses for this signature was performed in TCGA. We then verified the identified signature using International Cancer Genome Consortium (ICGC) data. After a series of analyses, we identified six hub genes (DNAJB6, RB1, VIMP/ SELENOS, STEAP3, BACH1, and ALOX12) that were then used to construct a model using a training data set. The model was then tested using a validation data set and was found to have high sensitivity and specificity. The identified ferroptosis-related hub genes might play a critical role in the mechanism of OV development. The gene signature we identified may be useful for future clinical applications.


2021 ◽  
Vol 11 (15) ◽  
pp. 6723
Author(s):  
Ariana Raluca Hategan ◽  
Romulus Puscas ◽  
Gabriela Cristea ◽  
Adriana Dehelean ◽  
Francois Guyon ◽  
...  

The present work aims to test the potential of the application of Artificial Neural Networks (ANNs) for food authentication. For this purpose, honey was chosen as the working matrix. The samples were originated from two countries: Romania (50) and France (53), having as floral origins: acacia, linden, honeydew, colza, galium verum, coriander, sunflower, thyme, raspberry, lavender and chestnut. The ANNs were built on the isotope and elemental content of the investigated honey samples. This approach conducted to the development of a prediction model for geographical recognition with an accuracy of 96%. Alongside this work, distinct models were developed and tested, with the aim of identifying the most suitable configurations for this application. In this regard, improvements have been continuously performed; the most important of them consisted in overcoming the unwanted phenomenon of over-fitting, observed for the training data set. This was achieved by identifying appropriate values for the number of iterations over the training data and for the size and number of the hidden layers and by introducing of a dropout layer in the configuration of the neural structure. As a conclusion, ANNs can be successfully applied in food authenticity control, but with a degree of caution with respect to the “over optimization” of the correct classification percentage for the training sample set, which can lead to an over-fitted model.


2019 ◽  
Author(s):  
Guangzhi Wang ◽  
Huihui Wan ◽  
Xingxing Jian ◽  
Yuyu Li ◽  
Jian Ouyang ◽  
...  

AbstractIn silico T-cell epitope prediction plays an important role in immunization experimental design and vaccine preparation. Currently, most epitope prediction research focuses on peptide processing and presentation, e.g. proteasomal cleavage, transporter associated with antigen processing (TAP) and major histocompatibility complex (MHC) combination. To date, however, the mechanism for immunogenicity of epitopes remains unclear. It is generally agreed upon that T-cell immunogenicity may be influenced by the foreignness, accessibility, molecular weight, molecular structure, molecular conformation, chemical properties and physical properties of target peptides to different degrees. In this work, we tried to combine these factors. Firstly, we collected significant experimental HLA-I T-cell immunogenic peptide data, as well as the potential immunogenic amino acid properties. Several characteristics were extracted, including amino acid physicochemical property of epitope sequence, peptide entropy, eluted ligand likelihood percentile rank (EL rank(%)) score and frequency score for immunogenic peptide. Subsequently, a random forest classifier for T cell immunogenic HLA-I presenting antigen epitopes and neoantigens was constructed. The classification results for the antigen epitopes outperformed the previous research (the optimal AUC=0.81, external validation data set AUC=0.77). As mutational epitopes generated by the coding region contain only the alterations of one or two amino acids, we assume that these characteristics might also be applied to the classification of the endogenic mutational neoepitopes also called ‘neoantigens’. Based on mutation information and sequence related amino acid characteristics, a prediction model of neoantigen was established as well (the optimal AUC=0.78). Further, an easy-to-use web-based tool ‘INeo-Epp’ was developed (available at http://www.biostatistics.online/INeo-Epp/neoantigen.php)for the prediction of human immunogenic antigen epitopes and neoantigen epitopes.


2014 ◽  
Vol 17 (1) ◽  
pp. 56-74 ◽  
Author(s):  
Gurjeet Singh ◽  
Rabindra K. Panda ◽  
Marc Lamers

The reported study was undertaken in a small agricultural watershed, namely, Kapgari in Eastern India having a drainage area of 973 ha. The watershed was subdivided into three sub-watersheds on the basis of drainage network and land topography. An attempt was made to relate the continuously monitored runoff data from the sub-watersheds and the whole-watershed with the rainfall and temperature data using the artificial neural network (ANN) technique. The reported study also evaluated the bias in the prediction of daily runoff with shorter length of training data set using different resampling techniques with the ANN modeling. A 10-fold cross-validation (CV) technique was used to find the optimum number of hidden neurons in the hidden layer and to avoid neural network over-fitting during the training process for shorter length of data. The results illustrated that the ANN models developed with shorter length of training data set avoid neural network over-fitting during the training process, using a 10-fold CV method. Moreover, the biasness was investigated using the bootstrap resampling technique based ANN (BANN) for short length of training data set. In comparison with the 10-fold CV technique, the BANN is more efficient in solving the problems of the over-fitting and under-fitting during training of models for shorter length of data set.


2018 ◽  
Vol 2018 ◽  
pp. 1-10
Author(s):  
Siyu Ji ◽  
Chenglin Wen

Neural network is a data-driven algorithm; the process established by the network model requires a large amount of training data, resulting in a significant amount of time spent in parameter training of the model. However, the system modal update occurs from time to time. Prediction using the original model parameters will cause the output of the model to deviate greatly from the true value. Traditional methods such as gradient descent and least squares methods are all centralized, making it difficult to adaptively update model parameters according to system changes. Firstly, in order to adaptively update the network parameters, this paper introduces the evaluation function and gives a new method to evaluate the parameters of the function. The new method without changing other parameters of the model updates some parameters in the model in real time to ensure the accuracy of the model. Then, based on the evaluation function, the Mean Impact Value (MIV) algorithm is used to calculate the weight of the feature, and the weighted data is brought into the established fault diagnosis model for fault diagnosis. Finally, the validity of this algorithm is verified by the example of UCI-Combined Cycle Power Plant (UCI-ccpp) simulation of standard data set.


2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
R. Manjula Devi ◽  
S. Kuppuswami ◽  
R. C. Suganthe

Artificial neural network has been extensively consumed training model for solving pattern recognition tasks. However, training a very huge training data set using complex neural network necessitates excessively high training time. In this correspondence, a new fast Linear Adaptive Skipping Training (LAST) algorithm for training artificial neural network (ANN) is instituted. The core essence of this paper is to ameliorate the training speed of ANN by exhibiting only the input samples that do not categorize perfectly in the previous epoch which dynamically reducing the number of input samples exhibited to the network at every single epoch without affecting the network’s accuracy. Thus decreasing the size of the training set can reduce the training time, thereby ameliorating the training speed. This LAST algorithm also determines how many epochs the particular input sample has to skip depending upon the successful classification of that input sample. This LAST algorithm can be incorporated into any supervised training algorithms. Experimental result shows that the training speed attained by LAST algorithm is preferably higher than that of other conventional training algorithms.


Heart ◽  
2018 ◽  
Vol 104 (23) ◽  
pp. 1921-1928 ◽  
Author(s):  
Ming-Zher Poh ◽  
Yukkee Cheung Poh ◽  
Pak-Hei Chan ◽  
Chun-Ka Wong ◽  
Louise Pun ◽  
...  

ObjectiveTo evaluate the diagnostic performance of a deep learning system for automated detection of atrial fibrillation (AF) in photoplethysmographic (PPG) pulse waveforms.MethodsWe trained a deep convolutional neural network (DCNN) to detect AF in 17 s PPG waveforms using a training data set of 149 048 PPG waveforms constructed from several publicly available PPG databases. The DCNN was validated using an independent test data set of 3039 smartphone-acquired PPG waveforms from adults at high risk of AF at a general outpatient clinic against ECG tracings reviewed by two cardiologists. Six established AF detectors based on handcrafted features were evaluated on the same test data set for performance comparison.ResultsIn the validation data set (3039 PPG waveforms) consisting of three sequential PPG waveforms from 1013 participants (mean (SD) age, 68.4 (12.2) years; 46.8% men), the prevalence of AF was 2.8%. The area under the receiver operating characteristic curve (AUC) of the DCNN for AF detection was 0.997 (95% CI 0.996 to 0.999) and was significantly higher than all the other AF detectors (AUC range: 0.924–0.985). The sensitivity of the DCNN was 95.2% (95% CI 88.3% to 98.7%), specificity was 99.0% (95% CI 98.6% to 99.3%), positive predictive value (PPV) was 72.7% (95% CI 65.1% to 79.3%) and negative predictive value (NPV) was 99.9% (95% CI 99.7% to 100%) using a single 17 s PPG waveform. Using the three sequential PPG waveforms in combination (<1 min in total), the sensitivity was 100.0% (95% CI 87.7% to 100%), specificity was 99.6% (95% CI 99.0% to 99.9%), PPV was 87.5% (95% CI 72.5% to 94.9%) and NPV was 100% (95% CI 99.4% to 100%).ConclusionsIn this evaluation of PPG waveforms from adults screened for AF in a real-world primary care setting, the DCNN had high sensitivity, specificity, PPV and NPV for detecting AF, outperforming other state-of-the-art methods based on handcrafted features.


Sign in / Sign up

Export Citation Format

Share Document