scholarly journals A Review of Oncologist’s Knowledge and Awareness Regarding Fertility Preservation

2021 ◽  
Vol 6 (3) ◽  
pp. 1-4
Author(s):  
Ghina Ghazeeri ◽  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Fertility Preservation ◽  
Survival Rates ◽  
Reproductive Age ◽  
The Core

The recent quantum leaps in various management modalities in oncology have led to unanticipated survival rates. This has constituted a plea for amelioration in the quality of life of cancer patients of reproductive age, at the core of which is Fertility Preservation (FP).

P–474 Psychosocial aspects of fertility preservation options for young cancer patients in the Czech Republic: a qualitative study

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
H Konecna ◽  
K Nováková
Keyword(s):  
Quality Of Life ◽  
Czech Republic ◽  
Cancer Patients ◽  
Fertility Preservation ◽  
Time Pressure ◽  
Treatment Plan ◽  
Reproductive Age ◽  
Structured Interviews ◽  
The Czech Republic

Abstract Study question What is the real accessibility of fertility preservation techniques and its perception by patients in the Czech Republic? Summary answer Fertility preservation options are not offered on a routine basis and often are not part of a treatment plan. Patients wish to be adequately informed. What is known already Every year, more than 82.000 people in the Czech Republic develop cancer. The incidence of newly diagnosed cancers in individuals in their reproductive age represents 4.4% of all newly diagnosed oncological diseases. Because the prognosis of treatment in this group of patients is very favourable, the priority in treatment is the emphasis on quality of life after surviving. One of the important parameters of quality of life for many people is the ability to reproduce and the possibility of having a genetic bond to their children. Study design, size, duration This qualitative study was conducted in 2019 and relied on explorative in-depth semi-structured interviews. Participants were chosen through occasional sampling. Participants/materials, setting, methods We interviewed 13 cancer patients/survivors in their reproductive age (aged 21 to 36; 7 females and 6 males); 4 close family members of young cancer patients; and 8 experts from relevant professional fields. Data gathered from semi-structured interviews were analysed by interpretative phenomenological analysis. Main results and the role of chance Cancer was perceived as a threat to life and one’s safety. It causes uncertainty and a feeling of loss of control. It also has a negative impact on a self-concept. Loss of fertility was perceived as a “injury of personality”. The possibility of maintaining fertility has increased the subjectively experienced quality of life. They make decisions under great time pressure, in a mentally demanding situation. They are usually in the early stages of coping with the diagnosis. The main factors that influenced the respondents’ decision were the amount and quality of information, psychological stress and time pressure. Patients and their families are interested in being informed about the risks that the disease and its treatment pose to their reproductive health. They want to be able to decide whether to undergo any of the fertility protection techniques. They want to keep their future open. It is therefore desirable that, within oncofertility, we focus on the process of passing on information and supporting decision-making on issues of fertility and its protection. A tool that could be a good informational platform may be so-called decision aid – a tool used to inform patients about available treatments, along with potential benefits, risks and costs. Limitations, reasons for caution As all qualitative data, our findings cannot be generalized. Selection bias could have occurred because it is likely that those interested and open to sharing participated. Wider implications of the findings: Oncofertility treatment is highly relevant and should be offered and discussed with all patients in their reproductive age. Addressing fertility preservation options should be a part of cancer treatment plan of all these patients. Trial registration number 0

scholarly journals The Current Status of Integrative Oncology in Korea

2021 ◽  
Vol 20 ◽  
pp. 153473542110638
Author(s):  
Eun-Bin Kwag ◽  
Soo-Dam Kim ◽  
Ji Hye Park ◽  
So-Jung Park ◽  
Mi-Kyung Jeong ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Causes Of Death ◽  
Survival Rates ◽  
Current Status ◽  
Integrative Oncology ◽  
Recurrence Rates ◽  
Current State ◽  
Look Ahead

Cancer is one of the leading causes of death worldwide, and Korea is no exception. Humanity has been fighting cancer for many years, and as a result, we now have effective treatments such as chemotherapy, radiation, and surgery. However, there are other issues that we are only now beginning to address, such as cancer patients’ quality of life. Moreover, numerous studies show that addressing these issues holistically is critical for overall cancer treatment and survival rates. This paper describes how Korea is attempting to reduce cancer incidence and recurrence rates while also managing the quality of life of cancer patients. Integrative Oncology is the field that addresses these broad issues, and understanding the current state of integrative oncology in Korea is critical. The goal of this paper is to provide an overview of the current state of integrative oncology in Korea as well as to look ahead to future developments.

Young-onset colorectal cancer treatment side effects: Infertility, sexual dysfunction, and quality-of-life outcomes.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 3587-3587
Author(s):  
Laura Diane Porter ◽  
Ronit Yarden ◽  
Kim Lynn Newcomer ◽  
Negeen Fathi ◽  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Side Effects ◽  
Sexual Dysfunction ◽  
Cancer Patients ◽  
Fertility Preservation ◽  
Cancer Treatments ◽  
Young Onset

3587 Background: Colorectal cancer is the third-most commonly diagnosed cancer and the second-leading cause of cancer death in men and women combined in the United States. Young-onset colorectal cancer refers to individuals diagnosed under the age of 50. In recent years, the incidence has increased by 2.2% annually in individuals younger than 50 years and 1% in individuals 50-64, in contrast to a 3.3% decrease in adults 65 years and older. Young-onset (YO) CRC patients and survivors face unique clinical challenges with fertility and sexual dysfunctions, but this risk is not well quantified. There is limited data and public discussion on the long-term effects of colorectal cancer treatments on fertility and sexual dysfunction and the long-term impact on the quality of life. Methods: To explore the unique challenges and unmet needs of the young-adult patient population, a cross-sectional study was conducted. Colorectal cancer patients and survivors (N = 884) diagnosed between the ages of 20 to 50 years old (median age 42 ± 7.0) completed an online questionnaire based on established instruments EORTC-QOL-30, EORTC-CR-29, and EORTC-SHC-22. Results: Thirty-one percent of respondents stated that a medical professional spoke to them about fertility preservation at the time of diagnosis and during treatment. Only 31% were referred to a reproductive endocrinologist, even though 37% of women and 16% of men reported that treatment left them infertile or sterile. Among survey respondents, 12% of women had an egg retrieval procedure, and 36% of men had their sperm preserved prior to the start of treatment. Fifty-three percent of women reported treatment led to premature menopause. Sixty-five percent of respondents suffer from some level of sexual dysfunction due to treatment. In patients who received radiation therapy, women were 12% less likely than men to have discussed sexual side effects with the provider before treatment. Patients who have an ostomy reported more severe sexual dysfunction (17.8%). Rectal cancer patients were 2.5 times more likely than those with colon cancer to report severe dysfunction after their treatment. More than 25% of the respondents said they would have considered alternative treatment if they would have known the risks of sexual dysfunction. Conclusions: Our survey demonstrates inadequate communications between patients and providers about the irreversible fertility and sexual effects of colorectal cancer treatments. Younger patients and survivors face unique long-term challenges and require further information about fertility preservation options and emotional support regarding their sexuality post-treatment. Other studies are needed to assess the physical and psychological side effects endured by young-onset CRC patients and survivors.

scholarly journals Advances in the Treatment and Prevention of Chemotherapy-Induced Ovarian Toxicity

2020 ◽  
Vol 21 (20) ◽  
pp. 7792
Author(s):  
Hyun-Woong Cho ◽  
Sanghoon Lee ◽  
Kyung-Jin Min ◽  
Jin Hwa Hong ◽  
Jae Yun Song ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Fertility Preservation ◽  
Ovarian Tissue ◽  
Alkylating Agents ◽  
Survival Rates ◽  
Chemotherapeutic Agents ◽  
Reproductive Age ◽  
Experimental Techniques ◽  
Ovarian Tissue Cryopreservation

Due to improvements in chemotherapeutic agents, cancer treatment efficacy and cancer patient survival rates have greatly improved, but unfortunately gonadal damage remains a major complication. Gonadotoxic chemotherapy, including alkylating agents during reproductive age, can lead to iatrogenic premature ovarian insufficiency (POI), and loss of fertility. In recent years, the demand for fertility preservation has increased dramatically among female cancer patients. Currently, embryo and oocyte cryopreservation are the only established options for fertility preservation in women. However, there is growing evidence for other experimental techniques including ovarian tissue cryopreservation, oocyte in vitro maturation, artificial ovaries, stem cell technologies, and ovarian suppression. To prevent fertility loss in women with cancer, individualized fertility preservation options including established and experimental techniques that take into consideration the patient’s age, marital status, chemotherapy regimen, and the possibility of treatment delay should be provided. In addition, effective multidisciplinary oncofertility strategies that involve a highly skilled and experienced oncofertility team consisting of medical oncologists, gynecologists, reproductive biologists, surgical oncologists, patient care coordinators, and research scientists are necessary to provide cancer patients with high-quality care.

scholarly journals Pretreatment fertility counseling and fertility preservation improve quality of life in reproductive age women with cancer

Cancer ◽  
2011 ◽  
Vol 118 (6) ◽  
pp. 1710-1717 ◽  
Author(s):  
Joseph M. Letourneau ◽  
Erin E. Ebbel ◽  
Patricia P. Katz ◽  
Audra Katz ◽  
Wei Z. Ai ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Fertility Preservation ◽  
Reproductive Age ◽  
Improve Quality ◽  
Reproductive Age Women ◽  
Fertility Counseling

scholarly journals Cardio-oncology: A Focus on Cardiotoxicity

2018 ◽  
Vol 13 (1) ◽  
pp. 64 ◽  
Author(s):  
Athanasios Koutsoukis ◽  
Argyrios Ntalianis ◽  
Evangelos Repasos ◽  
Efsthathios Kastritis ◽  
Meletios-Athanasios Dimopoulos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Targeted Therapies ◽  
Cancer Survival ◽  
Survival Rates ◽  
Standards Of Care ◽  
Improve Quality ◽  
Cardiovascular Morbidity And Mortality ◽  
Prevention And Treatment

Cardio-oncology is a recently developed field in cardiology aimed at significantly reducing cardiovascular morbidity and mortality and improving quality of life in cancer survivors. Cancer survival rates have been constantly increasing, mainly because of the advent of new, more potent and targeted therapies. However, many of the new therapies – along with some of the older chemotherapeutic regimens such as anthracyclines – are potentially cardiotoxic, which is reflected increasingly frequently in the published literature. Cardiotoxicity adversely affects prognosis in cancer patients, thus its prevention and treatment are crucial to improve quality and standards of care. This review aims to explore the existing literature relating to chemotherapy- and radiotherapy-induced cardiotoxicity. An overview of the imaging modalities for the identification of cardiotoxicity and therapies for its prevention and management is also provided.

scholarly journals Current and Future Perspectives for Improving Ovarian Tissue Cryopreservation and Transplantation Outcomes for Cancer Patients

2021 ◽  
Author(s):  
Sanghoon Lee ◽  
Sinan Ozkavukcu ◽  
Seung-Yup Ku
Keyword(s):  
Cancer Treatment ◽  
Cancer Patients ◽  
Fertility Preservation ◽  
Cancer Survival ◽  
Ovarian Tissue ◽  
Survival Rates ◽  
Reproductive Age ◽  
Ovarian Tissue Cryopreservation ◽  
Tissue Cryopreservation ◽  
Transplantation Outcomes

AbstractAlthough advances in cancer treatment and early diagnosis have significantly improved cancer survival rates, cancer therapies can cause serious side effects, including ovarian failure and infertility, in women of reproductive age. Infertility following cancer treatment can have significant adverse effects on the quality of life. However, established methods for fertility preservation, including embryo or oocyte cryopreservation, are not always suitable for female cancer patients because of complicated individual conditions and treatment methods. Ovarian tissue cryopreservation and transplantation is a promising option for fertility preservation in pre-pubertal girls and adult patients with cancer who require immediate treatment, or who are not eligible to undergo ovarian stimulation. This review introduces various methods and strategies to improve ovarian tissue cryopreservation and transplantation outcomes, to help patients and clinicians choose the best option when considering the potential complexity of a patient’s situation. Effective multidisciplinary oncofertility strategies, involving the inclusion of a highly skilled and experienced oncofertility team that considers cryopreservation methods, thawing processes and devices, surgical procedures for transplantation, and advances in technologies, are necessary to provide high-quality care to a cancer patient.

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