scholarly journals Primary morbidity of female military personnel serving in enterprises for disposing chemical weapons with organophosphate toxic substances (2007—2016)

2020 ◽  
pp. 48-59
Author(s):  
S. G. Grigoriev ◽  
V. I. Evdokimov ◽  
V. A. Sanzharevsky ◽  
G. G. Zagorodnikov
Keyword(s):  
Connective Tissue ◽  
Musculoskeletal System ◽  
Military Personnel ◽  
Armed Forces ◽  
Military Women ◽  
Chemical Weapons ◽  
Toxic Substances ◽  
Icd 10 ◽  
Group 2 ◽  
Group 1

Relevance. On September 27, 2017, Russia announced the completion of disposal of chemical weapons with organophosphorus toxic substances. ahead of its international obligations. Besides men, military women also served in enterprises for disposal of these weapons.Intention. To assess the impact of occupational factors on the primary morbidity of female military personnel (n = 267) served in enterprises for disposal of chemical weapons with organophosphates in 2007-2016.Methodology. The object of the study was data on the primary morbidity of female military personnel employed in disposal of chemical weapons with organophosphates (group 1) and serving in support and service units (group 2). The results were compared with the indicators of primary morbidity of all female military personnel Armed Forces of Russia. Nosologies were correlated with the chapters of diseases by the International Statistical Classification of Diseases and Related Health Problems (ICD-10).Results and Discussion. In Group 1 of female military personnel, the primary morbidity for a number of disease categories was better than in Group 2 and all the female military personnel of the Russian Armed Forces, which can be explained by careful preliminary selection before recruting, good work organization, and timely prevention of initial health disorders and rehabilitation of the functional reserves of the body. In military women of Groups 1 and 2, compared to all the female military personnel of the Russian Armed Forces, a statistically significantly higher level of primary morbidity was revealed for mental disorders and behavioral disorders (Chapter V by ICD-10). This can be explained by the cumulative effect of mental tension during disposal of chemical weapons. Of note, the above disorders were not the leading category of primary morbidity in both female military personnel working in enterprises and in all the female military personnel of the Russian Armed Forces. In female women of Group 1 compared to all the female military personnel of the Russian Armed Forces, there was a statistically significantly higher level of diseases of the musculoskeletal system and connective tissue (Chapter XIII by ICD-10). It can be assumed that negative memories of the likelihood of emergencies when moving weapons that require disposal create additional physical efforts and overstrain of individual muscles. It is appropriate to point out that diseases of the musculoskeletal system and connective tissue increased in female military personnel in all groups and overall in 2007-2016. In Group 1 of female military personnel, there was an increase in proportion of diseases from Chapter XIII vs certain stability of their percentage in all the female military personnel f the Russian Armed Forces.Conclusion. The results obtained showed a sufficient effectiveness of preventive and protective measures during the disposal of organophosphate weapons by female military personnel.

scholarly journals Specific features of the adhesion process of the abdominal cavity in children with different degrees of connective tissue dysplasia

2020 ◽  
Vol 10 (4) ◽  
pp. 381-389
Author(s):  
Sergey V. Minaev ◽  
Sergey I. Timofeev ◽  
Alina N. Grigorova ◽  
Oksana V. Vladimirova ◽  
Elena I. Pashneva ◽  
...  
Keyword(s):  
Growth Factor ◽  
Connective Tissue ◽  
Clinical Course ◽  
Abdominal Cavity ◽  
Type Iii Collagen ◽  
Type I ◽  
Type Iii ◽  
Connective Tissue Dysplasia ◽  
Group 2 ◽  
Group 1

Aim. To assess adhesions of the abdominal cavity in children with varying degrees of connective tissue dysplasia (CTD) severity. Methods. A total of 91 children with average age of 10.6 1.4 years were observed from 2005 to 2019. Composed of 53 boys (58.2%) and 38 girls (41.8%). Patients were divided into two groups: group 1 (69 children without CTD) and group 2 (22 children with CTD). Clinical data and screening cards were used to diagnose DST. All patients underwent an assessment for the clinical course, a macroscopic visual assessment adhesive process severity in the abdominal cavity according to three different scales (Nair, F. Coccolini, N.I. Ayushinova). Immunohistochemistry was performed against collagen I, III, IV type, Laminin 1, angiogenesis factors, transforming growth factor beta (TGF-), and Fibroblast Growth Factor Receptor 1 (FGFR1). A semi-quantitative counting method was used to record the relative number of immunopositive structures. Statistical analysis was carried out by methods of variation statistics using the Chi-square test and MannWhitney U-tests, as well as the Spearman rank correlation method for the reliability of differences between groups. Results. In the adhesive process visualization, the N.I. Ayushinov scale was revealed to be the most informative, showing the average score of 7 0.8 points in group 2 and 14 1.2 in group 1 (rs 0.35; p 0.05). In group 2, the adhesive material showed no (56%) or chaotic fragments (44%) of type I collagen, and the ratio of type I to type III collagen is 2.7: 5.1. In group 1, the ratio of type I to type III collagen is 5.9:1.8. The ratio of collagen IV to type I is 6.5: 2.9. Both groups have a moderate (++) amount of TGF-. TGF- is positive with macrophages. FGFR1 was found in the control group (++++). A positive response was seen in fibroblasts and macrophages (U = 79.00; p = 0.006). Statistically significant analyzes of vascular endothelial growth factor in compared groups (rs = 0.632, p 0.001) had a positive correlation.. Conclusion. Thus, the study showed features of clinical course and morphological changes during the development of adhesions in the abdominal cavity in children with varying degrees of severity of CTD. Data obtained dictate the need for an individual approach in predicting adhesive disease, as well as targeted preventive care.

scholarly journals The importance of matrix metalloproteases in the pathology of the tempo-mandibular joint in children

2020 ◽  
Vol 3 (5) ◽  
pp. 65-68
Author(s):  
Gaffarov S.A. ◽  
Saidov A.A.
Keyword(s):  
Connective Tissue ◽  
Temporomandibular Joint ◽  
Musculoskeletal System ◽  
Matrix Metalloproteases ◽  
Joint Diseases ◽  
Mandibular Joint ◽  
Tmj Dislocation ◽  
Icd 10 ◽  
Maxillofacial Abnormalities

Among the reasons for patients visiting a dentist, one of the most common is the pathology of the temporomandibular joint (TMJ), which occurs in 25-50% of the population [2,3,4]. According to the classification of ICD-10, TMJ diseases are classified as class XII " Maxillofacial abnormalities (including malocclusion) ”and Section 6“ Temporomandibular joint diseases ”, arthropathy and arthrosis of all joints of various etiologies are also described in class XIII“ Diseases of the musculoskeletal system and connective tissue ”. TMJ internal disorders are referred to in this classification by the terms “clicking jaw”, “TMJ dislocation and subluxation”.

Abstract 15925: Efficacy and Safety of Pulmonary Vein Isolation in Active Duty Military Members With Atrial Fibrillation

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Andrew S Wilson ◽  
Kelvin N Bush
Keyword(s):  
Atrial Fibrillation ◽  
Pulmonary Vein ◽  
Military Personnel ◽  
Active Duty ◽  
Efficacy And Safety ◽  
Group 4 ◽  
Group 3 ◽  
Group 2 ◽  
Af Recurrence ◽  
Group 1

Introduction: The efficacy and safety of pulmonary vein isolation (PVI) for atrial fibrillation (AF) in the active duty (AD) military population has not been previously reported. Hypothesis: We postulate that PVI is an efficacious and safe treatment for young AD service members with AF. Methods: AD military personnel with AF who underwent PVI from 2004 to 2019 were retrospectively analyzed in four age groups (group 1, n=26, 18 to 27 years; group 2, n=38, 28 to 37 years; group 3, n=28, 38 to 49 years; group 4, n=12, ≥50 years). Primary endpoints were (1) PVI procedural efficacy defined as no or rare AF recurrence (<6 episodes) 12 months after last PVI with or without antiarrhythmic drugs (AAD) and (2) procedure-related adverse events and complications. Results: 104 personnel (mean age 35.6+9 years, 84.6% paroxysmal AF, mean LVEF 60.2+6%, 19.2% maintained on AAD after PVI) underwent 142 PVI procedures with a mean follow up of 55.8+47 months. Procedural efficacy was attained in 96.2% of group 1, 78.9% of group 2, 75.0% of group 3, and 66.7% of group 4 (P=0.004, Figure 1). Freedom from AF was reached in 80.3% of group 1, 55.3% of group 2, 46.4% of group 3, 41.7% of group 4 (P=0.02). AADs were maintained in 11.5% of group 1, 21.0% of group 2, 14.3% of group 3, 41.7% of group 4 (P=0.144) and there was no difference in AF recurrence rates between those with AADs and those without (P=0.091). LVEF <50% trended towards being a significant predictor of AF recurrence (OR, 7; 95% CI, 0.75-65; P=0.051). Complications occurred in only 4 (3.8%) cases (pulmonary vein stenosis, cardiac tamponade, arteriovenous fistula) with no complications in the youngest group. Conclusions: This study suggests that PVI is an effective and safe therapy for younger military personnel with AF desiring to decrease their individual AF burden.

Comparative Assessment of Cognitive Function and Mood Dynamics in Patients with Depression and Eating Disorders in the Process of Treatment

2017 ◽  
Vol 41 (S1) ◽  
pp. S285-S285
Author(s):  
I. Makhortova ◽  
O. Shiryaev
Keyword(s):  
Eating Disorders ◽  
Eating Disorder ◽  
Cognitive Function ◽  
Rating Scale ◽  
Co Morbidity ◽  
Icd 10 ◽  
Group 2 ◽  
Competing Interest ◽  
Clinically Significant ◽  
Group 1

Eating disorders of bulimic type are among the most common comorbidities with depression. The objective is to evaluate cognitive function and mood dynamics in patients with depression and eating disorders in pharmacotherapy. In total, 52 outpatients, who met criteria for “major depressive episode” (ICD-10), participated. The level of depression was estimated with Hamilton Depression rating scale (HAM-D) and cognitive function–Montreal Cognitive Assessment (MoCa). Sample was divided into two groups. Patients of group 1 also met criteria for eating disorder of bulimic type and patients of group 2 did not have any eating disorder. Treatment included standard doses of SSRI. Assessments were performed after 2, 4 and 8 weeks (D14, D30, D60). The level of HAM-D was significantly greater (P < 0.05) in eating disorders group (16.75 ± 2.83 in group 1; 13.04 ± 1.93 in group 2 at screening) and significance was preserved till D60 (9.39 ± 2.54 in group 1; 6.32 ± 1.27 in group 2 at D60). Clinically significant antidepressive effect was revealed faster in group 2 (at D7) compared to group 1 (at D14). Overall score of MoCA was significantly lower (P < 0.05) in eating disorders group (20.33 ± 0.54 in group 1; 23.43 ± 2.32 in group 2 at screening) at all stages of treatment (23.39 ± 0.78 in group 1; 26.96 ± 3.27 in group 2 at D60) and it reached normal range (25 and more) only in group 2 at D60. Significant change from screening was revealed at D30 at group 2 and at D60 at group 1.ConclusionEating disorder have an impact on SSRI treatment efficacy including antidepressive and procognitive effects. It is necessary to reveal eating disorders as a co-morbidity in patients with depression.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Comparative analysis of medical and statistical indicators of morbidity in the military serving under contract in the Navy and Land Forces of Russia (2003–2018)

2019 ◽  
pp. 35-62 ◽  
Author(s):  
V. I. Evdokimov ◽  
P. P. Sivashchenko
Keyword(s):  
Military Personnel ◽  
Head Injuries ◽  
Armed Forces ◽  
The Body ◽  
Upper Respiratory Tract ◽  
State Of Health ◽  
Acute Infections ◽  
Icd 10 ◽  
Upper Respiratory ◽  
The Military

Relevance. When solving military-professional tasks during the period of reforming the Armed Forces of Russia, military servicemen under contract (sergeants, foremen, privates and sailors) are given a special role, and in a number of units they must replace conscripts.Intention To analize medical and statistical morbidity indicators of military personnel under contract in the Navy and the Land Forces of Russia.Methods. We studied medical reports on the state of health of personnel and medical service activity according to Form 3 / MED of military units, in which about 60% of the total number of servicemen of the Russian Armed Forces served from 2003 to 2018. Morbidity indicators were correlated with the International statistical classification of diseases and related health problems, 10th revision (ICD-10).Results and Discussion. As a rule, the military personnel under contract in the Russian Navy had lower morbidity rates with high dismissal rates. In particular, the indicators were as follows: the average annual overall morbidity rates were (855.0 ± 65.3) and (946.9 ± 49.7) ‰ in the military personnel under contract in the Russian Navy and in the Land Forces of Russia, respectively; primary incidence, (384.8 ± 19.3) and (472.0 ± 22.8) ‰, respectively (p < 0.01); need for follow-up, (92.8 ± 9.9) and (74.3 ± 4.7) ‰, respectively; hospital admission rates, (205.8 ± 39.2) and (235.2 ± 13.2) ‰, respectively; working days lost, (4,038 ± 203) and (3.944 ± 196) ‰, respectively; dismissal rates, (6.82 ± 0.57) and (4.40 ± 0.61) ‰, respectively (p < 0.01); mortality rates, (112.13 ± 9.91) and (111.76 ± 7.80) per 100,000 military personnel under contract. It is possible that this phenomenon was determined by the peculiarities of professional activity, the organization of medical support and the high demands placed on the state of health of the Russian Navy servicemen. A significant part of the leading disease blocks with a share of 0.5% or more in the structure of medical and statistical morbidity indicators, were similar between the military personnel under contract in the Navy of Russia and the Land Forces of Russia. In the structure of the assessed military-epidemiological significance of disease blocks among the military personnel under contract of the Russian Navy, acute infections of the upper respiratory tract (J00– 06 by ICD-10) ranked 1st, diseases of the esophagus, stomach and duodenum (K20–K31) ranked 2nd, followed by injuries involving several areas of the body (T08–T14), head injuries (S00–S09), ischemic heart disease (I20–I25). In the military personnel under contract in the Land Forces of Russia, these were the following diseases, from the most to least significant: acute infections of the upper respiratory tract (J00–J06), injuries involving several areas of the body (T08–T14), head injuries (S00–S09), diseases of the esophagus, stomach and duodenum (K20–K31), and infections of the skin and subcutaneous tissue (L00–L08).Conclusion. Prevention of the leading groups of disaeses will contribute to improving the health status of servicemen under contract, and taking data on morbidity into account will help organize diagnostic and treatment assistance and optimize the personnel and material resources of military medical organizations. 

scholarly journals Medical and statistical indicators of injuries among contract military personnel (privates, sergeants and foreman) in the Armed Forces of the Russian Federation (2003—2019)

2020 ◽  
pp. 87-104
Author(s):  
V. I. Evdokimov ◽  
P. P. Sivashchenko ◽  
V. V. Ivanov ◽  
V. V. Khominets
Keyword(s):  
Military Personnel ◽  
General Structure ◽  
Armed Forces ◽  
The Body ◽  
Icd 10 ◽  
External Causes ◽  
Foot Block ◽  
The Military ◽  
Statistical Indicators ◽  
Ankle And Foot

Relevance. The extreme conditions of the service determine the probability of servicemen' erroneous actions, stress, and often a decrease in the functional reserves of the body. This results in diseases and injuries.Intention: To analyze the indicators of injuries in the contract military personnel (privates, sergeants and foremen) of the Russian Armed Forces in 2003-2019.Methodology. The selective statistical analysis of medical reports on the state of health of military personnel by the form 3/MED was carried out. The military units with the contract military personnel about 80 % of the total personnel were under consideration. The indicators of injuries were correlated with the blocks (S00-T98) of the ICD-10 Chapter XIX “Injuries, poisoning and certain other consequences of external causes”.Results and their discussion. In 2003-2019, the injuries incidence among the contact military personnel by ICD-10 Chapter XIX was (18.39 ± 1.74) ‰. Its percentage in the general structure of incidence rate for all ICD-10 Chapters was (3.7 ± 0.3) %. Corresponding hospitalization rates were (12.12 ± 0.88) ‰ with the percentage of (5.0 ± 0.4) %, working days loss - (311.5 ± 26.0) ‰ and (7.9 ± 0.6) %, dismissal - (0.24 ± 0.03) ‰ and (6.2 ± 0.7) %, mortality - (51.48 ± 4.53) per 100 thousand of personnel and (50.5 ± 2.2) %, respectively. There was a decrease in the rate and proportion of injuries in the general structure of analyzed indicators of morbidity. The most common injuries among the contract military personnel were injuries to the head (ICD-10 Chapter XIX block 1, S00-S09), wrist and hand (block 7, S60-S69), ankle and foot (block 10, S90-S99), knee and lower leg (block 9, S80-S89), elbow and forearm (block 6, S50-S59), shoulder and upper arm (block 5, S40-S49). The structure of the types of injuries to the areas of the body was presented. The military epidemiological assessment of the significance of the contract military personnel injuries was performed. The 1st rank of the negative health effects significance was assigned to head injuries (block 1), injuries involving multiple body regions (block 11, T00-T07) ranked 2nd, sequelae of injuries, of poisoning and of other consequences of external causes (block 22, T90-T98) ranked 3rd, injuries to the ankle and foot (block 10) ranked 4th and injuries to the wrist and hand (block 7) ranked 5th. In total, these injuries amounted to 70.9 % of the assessed structure. Concerning trauma circumstances, many injuries occurred during off-duty hours (38.3 %). Injuries on combat duty comprised 3.4 %, during combat training - 17.4 %, on duty - 4.8 %, when using weapons and military equipment - 4.1 %, during household work - 5.4 %, during construction work - 1.7 %. Other circumstances were associated with 24.9 % of injuries.Conclusion. The obtained medical and statistical indicators of the injuries can determine the strategy of safe conditions for military professional activity, injuries prevention, medical and health promotion and rehabilitation measures for contract military personnel. 

scholarly journals Acellular dermal matrix and gingival connective in the treatment of periodontal recessions – comparative clinical evaluation in humans

2018 ◽  
Vol 1 (2) ◽  
Author(s):  
Mauricio Augusto Aquino Castro ◽  
Fabiano Araújo Cunha ◽  
Fernando Oliveira Costa ◽  
Elton Gonçalves Zenóbio ◽  
Maria Aparecida Gonçalves de Melo Cunha
Keyword(s):  
Connective Tissue ◽  
Acellular Dermal Matrix ◽  
Root Coverage ◽  
Dermal Matrix ◽  
Connective Tissue Graft ◽  
Tissue Graft ◽  
High Predictability ◽  
Group 2 ◽  
Acellular Dermal ◽  
Group 1

ABSTRACTDifferent periodontal surgical techniques have been proposed for the treatment of periodontal recessions. Among these, the graft of gingival connective tissue stands out for the high predictability of success. This work compared the clinical outcomes of treatment of periodontal recessions, using the gingival connective tissue grafts and acellular dermal matrix. A total of 72 recessions constituted the sample, divided equally into 2 groups. Group 1: treated with acellular dermal matrix graft (MDA) associated with the displaced: Group 2: treated with gingival connective tissue graft, also associated with the flap offset coronally. We evaluated the clinical parameters of probing depth, insert, clinical periodontal recession towards coronal-apical diameter mesio-distal of recessions, keratinized and mucosa thickness flap and influence of grafts in relation to root coverage. The initial measures were compared to those obtained with 45, 90 and 120 days after surgery. No statistically significant differences were found between the groups in terms of reduction of periodontal recessions, keratinized and mucosa flap thickness and of grafts in relation to root coverage. The Group 2 (CG) showed statistically significant reduction in the depth of drilling and clinical level of insertion, compared to group 1 (MDA). However, these differences were not clinically relevant. It was concluded that both the gingival connective tissue graft as the acellular dermal matrix can be used in the treatment of periodontal recessions, with a high predictability of success.Keywords: Gingival recession, connective tissue graft, acellular dermal matrix, periodontal surgery, gum recession, root coverage.

scholarly journals Comorbidities of mental and behavioral disorders in chemically dependent patients in different periods of abstinence

2012 ◽  
Vol 61 (3) ◽  
pp. 139-147 ◽  
Author(s):  
Maria de Lourdes Pereira Costa ◽  
Luiz Carlos Marques de Oliveira
Keyword(s):  
Behavioral Disorders ◽  
Psychotic Disorders ◽  
Psychosocial Care ◽  
Response To Treatment ◽  
Additional Information ◽  
Icd 10 ◽  
Group 3 ◽  
Group 2 ◽  
Mental And Behavioral Disorders ◽  
Group 1

OBJECTIVE: To assess the frequency of comorbidities of mental and behavioral disorders (CMBD) in psychoactive substance (PAS)-dependent patients with different periods of abstinence cared for at Alcohol and Other Drug Psychosocial Care Centers (CAPS-ad). METHOD: All patients under treatment in the two CAPS-ad of the city of Uberlândia-MG, between April and September 2010, were consecutively assessed. The ICD-10 symptom checklist was used to diagnose CMBD; additional information was obtained from interviews and medical records. The patients were divided according to duration of abstinence: < 1 week (Group 1); 1-4 weeks (Group 2); and > 4 weeks (Group 3). RESULTS: Of all patients assessed, 62.8% were diagnosed with CMBD, which were more frequent (p < 0.05) in Group 1 (72%) than Group 3 (54.2%), and both groups were similar to Group 2 (61%). Depressive and anxiety disorders were more frequent among patients of Group 1. Mood disorders were more frequent (p < 0.05) in women [22/34 (65%) vs. 54/154 (35.1%)], whereas psychotic disorders were more frequent (p = 0.05) in men [16/154 (10.4%) vs. 0]. The presence of CMBD was associated with more severe clinical conditions. CONCLUSIONS: The higher frequency of diagnosis of CMBD in patients of Group 1 may have resulted from the difficulties in distinguishing mental disorders that are due to PAS intoxication or withdrawal from those that are not. However, to make the diagnosis of CMBD, even during detoxification, can increase the likelihood of better response to treatment.

scholarly journals Comparison of the effectiveness of Trioxident and Сanal Mineral Trioxide agregate for capping perforations in the pulp cavity

2021 ◽  
Vol 25 (1) ◽  
pp. 35-41
Author(s):  
Ekaterina A. Lipetskaya ◽  
Taras V. Furtsev
Keyword(s):  
Therapeutic Potential ◽  
Cold Test ◽  
Modern Trend ◽  
Biological Method ◽  
Pulp Chamber ◽  
Minimal Invasiveness ◽  
Icd 10 ◽  
Group 2 ◽  
Group 1 ◽  
Clinical Cases

BACKGROUND: The modern trend of dentistry is the principle of minimal invasiveness. Preservation of the vitality of the tooth is an actual principle of operation. In the treatment of deep caries or pulpitis by a biological method, the pulp chamber is often opened. Even with bleeding, there is a chance to leave the tooth vital. After hemostasis, antibacterial treatment of the carious cavity and padding were performed. Domestic manufacturers offer two analogues for these purposes "Trioxident" and "Kanal MTA. AIM: The purpose of the study is to compare the effectiveness of domestic materials "Trioxident" and "Kanal MTA" when used as a therapeutic and insulating coating of pulp. MATERIALS AND METHODS: 27 clinical cases were analyzed in patients aged 2335 with a diagnosis of "deep dentine caries" K02.2 (according to ICD-10) of molars and premolars of the upper and lower jaws. All clinical cases combined patients' complaints of intermittent aching pains, the depth of carious cavities and the opened tooth cavity at one point. The patients were divided into two groups, in each of which the following stages of diagnosis and treatment were carried out. Diagnostics was carried out before the start of work and during examination after 7 days, 6, 12, 18 months. The stages of caries treatment were the same, only the materials for closing the perforations differed: in group 1 "Trioxidant", in group 2 "Kanal MTA". RESULTS: It is noted that the use of materials "Trioxident" and "Kanal MTA" is an effective choice for closing perforations of the pulp chamber in the treatment of deep caries and chronic pulpitis. Pain was absent in 30.8% and 42.1% of patients in groups 1 and 2, respectively. After 6, 12, 18 months, patients did not complain about the treated teeth, the cold test was positive for a short time in 26 cases, the average current at electroodontodiagnostic (minimum value 4, maximum value 8) was 5.6 A, 25 restorations had an Alpha rating according to Ryge criteria, in one case in group 1, the tooth crown darkened pointwise from the vestibular surface. CONCLUSION: The materials "Trioxident" and "Kanal MTA" are recommended for use in the biological method of pulpitis treatment. They have therapeutic potential to cover the pulp and are competitive in relation to the foreign equivalent of "MTA Prorut", which gives them an economic advantage in providing dental care within the framework of compulsory medical insurance.

scholarly journals Connective tissue dysplasia in the genesis of cervical incompetence

2021 ◽  
Vol 15 (1) ◽  
pp. 41-50
Author(s):  
E. V. Fotina ◽  
R. R. Zakirova ◽  
M. V. Alekseenkova ◽  
O. B. Panina
Keyword(s):  
Connective Tissue ◽  
Preterm Labor ◽  
Clinical Signs ◽  
Pregnancy And Childbirth ◽  
Cervical Incompetence ◽  
Connective Tissue Dysplasia ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

Aim: to study a role of undifferentiated connective tissue dysplasia (uCTD) in etiology of cervical incompetence and its effect on pregnancy and childbirth course.Material and Methods. There were enrolled 60 patients with cervical incompetence. Patients were divided into 3 groups according to the modified CTD scale: group 1 - patients without uCTD (n = 21); group 2 - patients with mild uCTD (n = 25); group 3 - patients with moderate-to-severe uCTD (n = 14). Intensity of CTD clinical signs was assessed based on health status, gynecological and obstetric history, the course of pregnancy, labor and the postpartum period.Results. It was found that patients with more prominent CTD developed earlier (r-Spearman = -0.26) and more marked (r-Spearman = -0.29) cervical shortening and opening of the internal orifice of the uterus (r-Spearman = 0.28). It was also noted that likelihood of occurring preterm labor was significantly higher in patients with CTD (p = 0.02).Conclusion. The data obtained evidence that uCTD affects intensity of manifested cervical insufficiency and rate of preterm delivery.

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