scholarly journals Pharmacy, the continuously expanding field of science

2022 ◽  
Vol 3 (1) ◽  
pp. 185-186
Author(s):  
Pál Perjési ◽  
Keyword(s):  
Human Body ◽  
Pharmaceutical Chemistry ◽  
Pharmaceutical Sciences ◽  
Active Compounds ◽  
Pharmaceutical Technology ◽  
Pharmacology And Toxicology ◽  
Herbal Formulations

Originating from the traditional herbal formulations, nowadays, Pharmacy covers all the disciplines focusing on the behavior of complex pharmaceutical forms, drug-releasing systems, and active compounds in the human body. Masters of pharmaceutical sciences must know the basics of pharmaceutical chemistry, pharmaceutical technology, biotechnology, biology, physiology, pharmacology, and toxicology.

Fast Dissolving/Disintegrating Dosage Forms of Natural Active Compounds and Alternative Medicines

2020 ◽  
Vol 14 (1) ◽  
pp. 21-39
Author(s):  
Anupama Singh ◽  
Vandana Kharb ◽  
Vikas Anand Saharan
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Active Compound ◽  
Dosage Forms ◽  
Oral Ingestion ◽  
Active Compounds ◽  
Alternative Medicines ◽  
Alternative Systems ◽  
The Family ◽  
Herbal Formulations

Fast Dissolving/Disintegrating Dosage Forms (FDDFs) are a group of dosage forms which dissolve or disintegrate quickly, leading to fast distribution of active ingredients at the site of administration; thereby providing ease of oral ingestion of solid unit dosage forms and have the potential to enhance transmucosal absorption. With time, the use of FDDFs in alternative systems has significantly increased. Homeopathic systems and traditional Chinese medicine have embraced FDDFs for the delivery of active compounds. Most of the patents in this area are from China or by the Chinese innovators. In Europe and US, FDDFs have been extensively studied for the delivery of natural active compounds. It was fascinating to know that some new dosage forms and new routes of delivering active compounds are also making their way to the family of FDDFs. The dose of active compound, size of dosage forms, standardization of extracts, polyherbal mixtures, stability of active compounds, safety, efficacy and pharmacokinetics are challenging issues for developing FDDF herbal formulations or phytopharmaceuticals.

Issues of pharmaceutical specialist admission to work

2021 ◽  
pp. 76-80
Author(s):  
Tatiana L. Moroz ◽  
Olga A. Ryzhova
Keyword(s):  
Pharmaceutical Chemistry ◽  
Staff Turnover ◽  
Occupational Structure ◽  
Quality Of Work ◽  
Resident Physicians ◽  
Pharmaceutical Technology ◽  
Irkutsk Region ◽  
The Right

A study was carried out to identify differences in training of resident physicians in the specialties: Management and Economics of Pharmacy, Pharmaceutical Technology, Pharmaceutical Chemistry and Pharmacognosy and under the specialist’s program Pharmacy and to explore the possibilities of granting pharmacy workers the right to transit from one specialty to another without compulsory completion of residency. The urgency of this article is associated with a large number of issues that are being faced by pharmacists who transit from one specialty to another.An analysis of the age and occupational structure of pharmacists improving their qualifications (2300 people) was conducted in the Irkutsk region and the Trans-Baikal Territory. The results of the study showed that it seems like a good idea not to associate the transition from one specialty to another with the obligatory completion of residency, but to provide an admission to work as a pharmacist-technologist after initial accreditation, taking into account the specifics of the work of pharmaceutical specialists in pharmacies, the need to ensure the interchangeability of workers and reduce staff turnover without falling off in quality of work.

scholarly journals A Bibliometric Analysis of Pharmaceutical Sciences-Related Articles in Qatar from 2013-2020

2021 ◽  
pp. 116-126
Author(s):  
Sourour Idoudi ◽  
Mohamed Izham Mohamed Ibrahim ◽  
Feras Alali ◽  
Nashiru Billa
Keyword(s):  
Web Of Science ◽  
Research Output ◽  
Science Research ◽  
Pharmaceutical Chemistry ◽  
Journal Ranking ◽  
Publication Date ◽  
Annual Growth Rate ◽  
Pharmaceutical Sciences ◽  
Pharmaceutical Science ◽  
Priority Areas

Backgrround: Pharmaceutical science is an important area in drug discovery and therapies.The research output generated from pharmaceutical sciences research is critical for psychological, physical, and social wellbeing. This study was carried out to analyze Qatar's quantity and quality of pharmaceutical sciences-related research and map out a national research roadmap and priority areas. Materials and Methods: A systematic search was carried out in the Web of Science, Scopus, Pub Med, and Google Scholar databases using the search terms “Pharmaceutical Science,” “Pharmaceutical Chemistry,” “Medicinal Chemistry,” “Pharmacology,” “Pharmaceutics,” “Pharmacokinetics,” “Physiology,” “Pharmaceutical Science research,” “Study,” other relevant terms related to Pharmaceutical Sciences field and “Qatar.”The search covered eight years. The data extracted included the title, keywords, publication date, authors, publishing journal, journal ranking, impact factor, type of article, number of citations, the sum of citations, H-index, etc. Results: The search yielded123 studies. Most were original articles (n=100, 81.3%), published in 2019 (n=27, 22.0%), applied research (n=68, 55.3%),indexed in Web of Science (n=120, 97.6%),published under the subject of pharmacology (n=43, 42.6%), focused on cancer (n=46, 37.4%)and produced by five authors (n=19, 18.8%) and more than eight authors (n=19, 18.8%). Hamad Medical Corporation (HMC) was the main collaborator (n=16, 13.0%). Fifty-four (43.9%) of the articles were published in journals ranked as Q1. Conclusions: A total of 123 articles were published, with an average annual growth rate of 6.7% in publications and 946 citations. A high number of publications were in Q1 and Q2 journals. The research focus (e.g., cancer and cardiovascular) was established according to the country’s research roadmap and priority areas.

scholarly journals Establishment of Standardization Parameters for Herbal Formulation, Swarasa Bhvit Amalaka Churnam

2019 ◽  
Vol 9 (4-A) ◽  
pp. 108-121
Author(s):  
Vihangesh Kumar Dixit ◽  
Raghuveer Irchhaiya ◽  
Nandlal Singh ◽  
Rishikesh Gupta
Keyword(s):  
Human Health ◽  
Human Body ◽  
Phytochemical Screening ◽  
Main Ingredient ◽  
Foreign Matter ◽  
Organoleptic Evaluation ◽  
Herbal Formulation ◽  
Simple Processing ◽  
Herbal Formulations

Herbal formulations are very useful for human health because of their natural and simple processing. A quality herbal formulation must pass the test for their characteristic properties. Inspite of the large number of Ayurvedic formulations are available in the market, standards of their quality are yet to be laid. Amlaka churnam or amalaki rasayanam is a swarasa bhavita, important herbal formulation used for treatment related to immunity systems of human body. In addition to this it is also used for nurturing of skin, heart, eye and stomach. The main ingredient of amalaka churnam is amla (Embalica officinalis) family Euphorbiaceae. Though amalaka churnam is described in many classical Ayurvedic granthas, but there are minor differences in their formulations. Also marketed formulations of amalaki rasayanam by manufacturers do not have description about its standardization.  Therefore, it is necessary to develop standard parameters for establishment of quality of the formulation. In this work, a standardization of herbal formulations of amalaka churnam is reported in terms of organoleptic evaluation of ingredients with rasayana formulation, loss of drying analysis, foreign matter, phytochemical screening, pH estimation, evaluation of ash value, extractive value and rheological evaluation. Keywords: Bhvit, amalaka Churnam, Organoleptic, rheological etc.

Study of Desorbtion and Exemption of Terpeno-indole Alkaloids of Vinkristin and Vinblastin from Erythrocitary Cell Carriers

2019 ◽  
Vol 8 (2) ◽  
pp. 16-21 ◽  
Author(s):  
O. V. Trineeva ◽  
A. D. Khalahakun
Keyword(s):  
Average Rate ◽  
Indole Alkaloids ◽  
Pharmaceutical Chemistry ◽  
Peg 400 ◽  
Modified Method ◽  
Pharmaceutical Technology ◽  
Peg 4000 ◽  
Cell Carriers ◽  
Modified Media ◽  
Modified Forms

Introduction. Employees of the Department of Pharmaceutical Chemistry and Pharmaceutical Technology have obtained modified forms of terpino-indole alkaloids (ТIA) and vinbristine (VCR) and vinblastine (VBL) known in the treatment of cancer diseases by incorporating them into the erythrocyte carriers (EN) by the modified method of hypoosmotic lysis in the modified (aprotic solvent dimethyl sulfoxide (DMSO) and polyethylene glycol (PEG 4000) and unmodified media.Aim. The aim of the work was to study the desorption and release of terpene-indole vincristine and vinblastine alkaloids from previously obtained cellular erythrocyte carriers.Materials and methods. In the experiment performed, the release characteristics of encapsulated preparations from erythrocytes were determined. TIA preparations were released from erythrocyte form in 6 hours: VCR – 54.5305%, VCR : PEG-4000 (1:5) – 53.3305%, VCR : PEG-4000 (1:10) – 40.1283%, VCR : PEG-4000 (1:20) – 39.9869%, VCR : DMSO (2 mg/ml) – 54.2354%, VBL – 68.0656%; VBL : PEG-4000 (1:10) – 63.8941%; VBL : PEG-4000 (1:20) – 60.7455%; VBL : PEG-400 (1:20) – 60.3529%; VBL : DMSO (2 mg/ml) – 64.5006%. The rate of release from an erythrocyte form encapsulated in a medium modified with DMSO is significantly higher than that encapsulated in an unmodified medium. The average rate of TIA release from erythrocyte forms encapsulated in PEG medium is approximately the same.Results and discussion. The results show that the release of hemoglobin from TIA encapsulated erythrocytes compared with non-encapsulated EN is small. The results show that, on average, 8.242 ± 0.3135% of hemoglobin is released from TIA encapsulated with EN, compared to control erythrocytes – 7.53% after 6 h of incubation at 37 °C. The release of hemoglobin from the TIA of encapsulated erythrocytes in modified media is less than that encapsulated in unmodified medium.Conclusion. Based on these results, it can be suggested that PEG can bind to the erythrocyte membrane and stabilize it.

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