scholarly journals Relationship between dermatoglyphics and cleft lip and/or palate: a review of literature

2017 ◽  
Vol 21 (2) ◽  
pp. 20-25
Author(s):  
Cristian Díaz ◽  
Habib Barhoum
Keyword(s):  
Environmental Factors ◽  
Cleft Palate ◽  
Key Words ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Embryonic Tissue ◽  
Review Of Literature ◽  
Orofacial Clefts ◽  
Genetic And Environmental Factors ◽  
Period Of Gestation

This article reviews the concepts associated with dermatoglyphs such as their classification, characteristics and applications. It also reviews orofacial clefts such as cleft lip and palate and proposes a possible relationship between dermatoglyphics and these orofacial clefts, entities that are considered isolated at first, but considering that they are derived from the same embryonic tissue, the ectoderm, and their development is in the same period of gestation, making genetic and environmental factors that would influence the development of the asyndromic lip and / or palate could be reflected in the fingerprints and the type of pattern that they follow. Key words: Cleft lip, dermatoglyphics, cleft palate, fingerprint.

Morphological Presentation of Orofacial Clefts: An Epidemiological Study of 5004 Patients in a Tertiary Care Hospital of Central India

2021 ◽  
pp. 105566562110577
Author(s):  
Jaideep Singh Chauhan ◽  
Sarwpriya Sharma
Keyword(s):  
Cleft Palate ◽  
Epidemiological Study ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Tertiary Care ◽  
Central India ◽  
Care Hospital ◽  
Orofacial Clefts ◽  
Chi Square ◽  
The Right

Objective: To analyse the morphological presentation of orofacial clefts, gender, syndromes and systemic anomalies associated with them. Design: This was an epidemiological study performed in the patients who were registered for cleft lip and palate surgeries in our centre. The data was evaluated both retrospectively as well as prospectively. Patients/ Participants: The patients registered from November 2006 to April 2021 were studied. Out of 5276 patients, data of 5004 cases were analysed, rest 272 patients were excluded due to lack of information. Statistical analysis and Chi square test were applied. Results: Cleft deformities were more common in males than females. Cleft lip with palate was the commonest phenotype (52.2%). It was followed by isolated cleft lip (22.9%), isolated cleft palate (22.1%), rare clefts (1.62%) and syndromic clefts (1.18%). Unilateral variants were more frequent than bilateral. In unilateral, left side was more common than the right side. Among bilateral, most of the cases had premaxillary protrusion. In the present study, 3.46% of all the patients had associated anomalies affecting their other organs. Less common cleft phenotypes like microform cleft lip and submucous cleft palate ± bifid uvula showed frequency of 0.62% and 0.64% respectively. Conclusion: Thorough examination of cleft deformity should be done as it may appear as an isolated deformity or part of a syndrome and have associated systemic anomalies. This may help us to deliver comprehensive care to the patients and can prevent potential operative complications.

Surgical Repair of Orofacial Clefts in North Kivu Province of Eastern Democratic Republic of Congo (DRC)

2020 ◽  
Vol 57 (11) ◽  
pp. 1314-1319
Author(s):  
Luc Malemo Kalisya ◽  
Jacques Fadhili Bake ◽  
Bake Elisee ◽  
Kavira Nyavandu ◽  
Robert Perry ◽  
...  
Keyword(s):  
Cleft Palate ◽  
Cleft Lip ◽  
Democratic Republic ◽  
Cleft Lip And Palate ◽  
Surgical Repair ◽  
Democratic Republic Of Congo ◽  
Orofacial Clefts ◽  
Republic Of Congo ◽  
General Surgeons ◽  
North Kivu

Background: There is a high prevalence of orofacial clefts in low- and middle-income countries with significant unmet need, despite having 50% of the population younger than 18 years in countries such as the Democratic Republic of Congo (DRC). The purpose of this article is to report on the experience of general surgeons with orofacial clefts at a single institution. Methods: This is a retrospective study of patients treated for cleft lip/palate in the province of North Kivu, DRC between 2008 and 2017. Results: A total of 1112 procedures (122/year) were performed. All procedures were performed by general surgeons following training by an international nongovernmental aid organization. A total of 59.2% of patients were male and the median age was 3.4 years (interquartile range: 0.7-13 years). Average distance from surgical center to patient location was 242.6 km (range: 2-1375 km) with outreach performed for distances >200 kms. A majority (82.1%) of patients received general anesthesia (GA) with significant differences in use of GA, age, weight, and length of stay by major orofacial cleft category. Of the 1112 patients, 86.1% were reported to have cleft lip alone, 10.5% had cleft lip and palate, and 3.4% cleft palate alone. Despite this, only 5.3% of patients underwent surgical repair of cleft palate. Conclusions: Multiple factors including malnutrition, risk of bleeding, procedural complexity, and cosmetic results may contribute to the distribution of procedures performed where most cleft palates are not treated. Based on previously published estimates, unmet needs and social burden of cleft lip and palate are high in the DRC.

scholarly journals Incidence of Orofacial Clefts in Kumasi, Ghana

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
P. Agbenorku ◽  
M. Yore ◽  
K. A. Danso ◽  
C. Turpin
Keyword(s):  
Cleft Palate ◽  
Congenital Anomalies ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Orofacial Clefts ◽  
Female Ratio ◽  
Live Births ◽  
Male Female Ratio ◽  
Cleft Lip Palate ◽  
History Of

Background. Cleft lip and cleft palate are among the most common orofacial congenital anomalies. This study is to establish Orofacial Clefts Database for Kumasi, Ghana, with a view to extend it to other cities in future to obtain a national orofacial anomaly database. Methods. A descriptive prospective survey was carried out at eleven selected health facilities in Kumasi. Results. The total number of live births recorded was 27,449. Orofacial anomalies recorded were 36, giving an incidence of 1.31/1000 live births or 1 in 763 live births. The mean maternal age of cleft lip/palate babies was 29.85 years (range 18–40 years). The male : female ratio for the orofacial anomalies babies was 1.3 : 1; the male : female ratio was 0.5 : 1 in the cleft lip group, 1.3 : 1 in the cleft lip and palate group, and 4 : 1 in the cleft palate group. The majority of clefts were unilateral (69.4%, n=25), with females (n=14) outnumbering males (n=11). A family history of cleft was recorded with five babies (13.9%). Associated congenital anomalies were recorded in seven (19.4%) cleft lips and/or palates. Conclusion. The incidence of 1 in 763 live births found in this study indicates that cleft lip/palate is a common congenital anomaly in Kumasi.

scholarly journals Cárie Dentária em Indivíduos com Fissuras Labiopalatinas: Revisão de Literatura

UNICIÊNCIAS ◽  
2021 ◽  
Vol 24 (1) ◽  
pp. 112-117
Author(s):  
Andreza Maria Fábio Aranha ◽  
Amanda Alves de Oliveira ◽  
Alexandre Meireles Borba ◽  
Luiz Evaristo Ricci Volpato
Keyword(s):  
Oral Health ◽  
Dental Caries ◽  
Cleft Palate ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Public Health Practice ◽  
Well Being ◽  
Individualized Approach ◽  
Genetic And Environmental Factors ◽  
Isolated Cleft Palate

As fissuras labiopalatinas (FLP) são as malformações congênitas mais comuns da região craniofacial e apresentam diferentes fenótipos e características clínicas, que diferem entre si de acordo com as estruturas anatômicas envolvidas: fissura de lábio, fissura de lábio e palato e fissura de palato isolada. A etiologia das FLP é multifatorial e inclui fatores genéticos e ambientais. O objetivo do presente estudo foi investigar o papel das fissuras labiopalatinas na prevalência de cárie dentária por meio de uma revisão na literatura. O defeito anatômico que envolve o rebordo alveolar e/ou o palato pode resultar em agenesias dentárias, dentes supranumerários, anomalias de forma e estrutura, bem como atresia maxilar, mordidas cruzadas posteriores e apinhamentos dentários. Também, a presença da FLP pode resultar aos indivíduos problemas durante alimentação, pronúncia de alguns fonemas, audição e integração social, o que poderia afetar a qualidade de vida do indivíduo e da dinâmica familiar. Quando a saúde bucal de crianças e adolescentes com FLP foi investigada, maior retenção do biofilme microbiano nas superfícies dentárias, de inflamação gengival e maior ocorrência de cárie dentária foram observados. Para um diagnóstico e tratamento adequados, é fundamental uma abordagem multidisciplinar, individualizada, para orientação e planejamento do tratamento dos indivíduos com a malformação, desde o nascimento até a fase adulta. O conhecimento dos efeitos da FLP na saúde bucal e no bem-estar dos indivíduos e das famílias afetadas é fundamental para mudanças nas políticas públicas das práticas de saúde e redução da sobrecarga da presença da malformação congênita.   Palavras-chave: Cárie Dentária. Fenda Labial. Fissura Palatina. Saúde Bucal   Abstract Cleft lip and palate (CLP) are the most common congenital malformations of the craniofacial region and they present different phenotypes and clinical characteristics, which differ according to the anatomical structures involved: cleft lip, cleft lip and palate and isolated cleft palate. The etiology of CLP is multifactorial and includes genetic and environmental factors. The aim of this study was to investigate the role of cleft lip and palate in the prevalence of dental caries through a literature review. The anatomical defect involving the alveolar ridge and / or the palate can result in dental agenesis, supernumerary teeth, anomalies in shape and structure, as well as maxillary atresia, posterior cross bites and dental crowding. Also, the presence of CLP can result in problems for individuals during feeding, pronunciation of some phonemes, hearing and social integration, which could affect the individual's quality of life and family dynamics. When the oral health of children and adolescents with CLP was investigated, greater retention of microbial biofilm on dental surfaces, gingival inflammation and the occurrence of dental caries were observed. For an adequate diagnosis and treatment, a multidisciplinary and individualized approach is essential to guide and plan the treatment of individuals with the malformation, from birth to adulthood. The knowledge of the effects of FLP on oral health and on the well-being of affected individuals and families is fundamental to changes in public health practice policies and to reduce the burden of the presence of the congenital malformation.   Keywords:  Cleft Lip. Cleft Palate. Dental Caries. Oral Health.

scholarly journals Fatores de Riscos na Fissura Labiopalatina Não Sindrômica

UNICIÊNCIAS ◽  
2021 ◽  
Vol 24 (1) ◽  
pp. 86-93
Author(s):  
Carla Meliso Rodrigues Silvestre ◽  
Renata Cristina Giroto Ferreira da Silva ◽  
Ageo Mario Candido da Silva ◽  
Walkiria Shimoya Bittencourt ◽  
Yolanda Benedita Abadia Martins de Barros ◽  
...  
Keyword(s):  
Risk Factors ◽  
Environmental Factors ◽  
Literature Review ◽  
Cleft Palate ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
First Trimester ◽  
Human Beings ◽  
Factors Associated ◽  
Narrative Literature Review

As anomalias craniofaciais representam um grupo amplo de malformações congênitas que afetam uma grande proporção da sociedade mundial. Entre essas se encontram as fissuras de lábio e/ou de palato, anomalia orofacial mais frequente entre os seres humanos que ocasionam problemas estéticos e funcionais nos indivíduos afetados.  A etiologia das fissuras labiopalatinas isoladas ou não-sindrômicas é complexa e multifatorial, associadas à fatores hereditários e ambientais. Este estudo teve como objetivo relatar os fatores genéticos e ambientais associados à etiologia desse tipo de malformação, através de uma revisão narrativa de literatura, a partir das bases de dados: PubMed e Scielo. Os descritores utilizados foram: cleft palate AND cleft lip AND etiology AND risk factors. Incluíram-se artigos nos idiomas inglês e português publicados em periódicos nacionais e internacionais acerca da temática da pesquisa. Baseado na revisão de literatura se pode identificar que os fatores ambientais como: fumo, consumo de álcool, consumo de medicamentos, o não uso de suplementação com polivitamínicos e ácido fólico, exposição a agrotóxicos, idade dos genitores podem aumentar a chance de ocorrência das fissuras labiopalatinas. O acompanhamento gestacional durante o primeiro trimestre gestacional se faz necessário, a fim de monitorar os fatores de risco associados com as fissuras labiopalatinas não sindrômicas.   Palavras-chave: Fissura Palatina. Fenda Labial. Etiologia. Fatores de Risco.   Abstract Craniofacial anomalies represent a broad group of congenital malformations that affect a large proportion of world society. Among them are cleft lip and / or palate, the most frequent orofacial anomaly among human beings that cause aesthetic and functional problems in the affected individuals. The etiology of isolated or non-syndromic cleft lip and palate is complex and multifactorial, associated with hereditary and environmental factors. This study aimed to report the genetic and environmental factors associated with the etiology of this type of malformation through a narrative literature review conducted in October 2020, using the PubMed and Scielo databases. The keywords used were cleft palate AND cleft lip AND etiology AND risk factors. Articles in English and Portuguese published in national and international journals about the research theme were included. Based on the literature review, it can be identified that environmental factors such as smoking, alcohol consumption, medication consumption, the non-use of supplementation with multivitamins and folic acid, exposure to pesticides, age of parents can increase the chance of cleft lip and palate occurrence. Gestational monitoring during the first trimester of pregnancy is necessary in order to monitor the risk factors associated with non-syndromic cleft lip and palate.   Keywords: Cleft Palate. Cleft Lip. Etiology. Risk Factors.

scholarly journals Orofacial Closure Defects: Forty-Five Genes Associated Cleft Lip and Palate

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Sahar Ashouri ◽  
Hamidreza Khorramkhorshid ◽  
Asghar Ebadifar
Keyword(s):  
Environmental Factors ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Data Extraction ◽  
Scientific Information ◽  
Facial Growth ◽  
The Face ◽  
Genetic And Environmental Factors ◽  
High Level ◽  
National Databases

Context: Cleft lip and palate (CLP) is the most common congenital malformations in the face and neck. Given that the inheritance of this disease is multifactorial and both genetic and environmental factors play crucial roles in its creation, studying these factors may be a step toward reducing the prevalence of the disease in future generations. Method: For this study, we looked through several national and international databases, consisting of Scientific Information Database, IranDoc, ScienceDirect, Google Scholar, PubMed, and Scopus. Based on our search method, we found 800 published articles, of which 750 were obtained from the international databases, and the remaining 50 were extracted from the national databases. After data refining, 600 articles with eligible criteria remained for data extraction, and data related to embryological origin, classification and etiology, genes and environmental factors, and complications caused by CLP were collected. Results: The CLP etiology was multifactorial and involved both genetic and environmental risk factors. The primary purpose of this review was to give the reader an overview of studies on multifactorial causes of this congenital disability. The functions of genes are very different, indicating a high level of vulnerability in the cranial and facial growth pathways. Conclusions: These findings have advanced our understanding of genes associated with CLP and genetic polymorphisms involved in orofacial closure defects. The findings can create new clinical and molecular research opportunities.

scholarly journals Desenvolvimento dental e idade cronológica em pacientes com fissuras labiopalatinas: uma revisão de literatura

2020 ◽  
Vol 8 (9) ◽  
Author(s):  
Andressa Cavalcanti Pires ◽  
Marina Tavares Costa Nóbrega ◽  
Tânia Braga Ramos ◽  
Rosa Helena Wanderley Lacerda
Keyword(s):  
Cleft Palate ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Maxillofacial Surgery ◽  
Epidemiologic Study ◽  
Sao Paulo ◽  
Oral And Maxillofacial Surgery ◽  
São Paulo ◽  
Orofacial Clefts ◽  
Dental Maturation

Introdução: A idade dentária representa um aliado na avaliação da idade fisiológica, que comparada a idade cronológica, podem orientar quanto as alterações de desenvolvimento. Objetivo: Avaliar o atraso de desenvolvimento dental relacionado a idade cronológica do indivíduo portador de fissura labiopalatina. Material e método: Para realização da revisão da literatura foi utilizada abordagem indutiva e técnica documental baseada na literatura pré-existente sobre o assunto. A pesquisa abrange a busca de artigos publicados nas bases de referências bibliográficas PUBMED, Portal de Periódicos CAPES, SCIELO e BIREME. Utilizou-se como descritores: “odontogênese”, “fissura labial”, “fissura palatina”, “odontogenesis”, “cleft lip” e “cleft palate”. Resultados: Após excluídas as duplicatas, 34 artigos foram encontrados nas bases de dados selecionadas. Sendo 32 na base Pubmed, 25 na base Bireme, 04 no Portal de Periódicos CAPES e nenhum na base Scielo. Destes, 04 foram selecionados para análise. Conclusão: Pode-se concluir com esse trabalho que existe um atraso no desenvolvimento dentário de pacientes com fissura lábiopalatina em relação aos pacientes não fissurados e um atraso no desenvolvimento dentário de 6 meses deve ser considerado ao planejar o tratamento e cirurgias. É inconclusiva a diferença relacionada ao gênero.Descritores: Odontogênese; Fissura Labial; Fissura Palatina.ReferênciasVellini-Ferreira F. Ortodontia: Diagnóstico e Planejamento Clínico. 7. ed. São Paulo: Artes Médicas Ltda; 2008.Carrara CFC. Estudo da cronologia e sequência de erupção e das agenesias dos dentes permanentes em indivíduos brasileiros, leucodermas, portadores de fissura transforame incisivo unilateral [dissertação]. Bauru: Faculdade de Odontologia de Bauru - USP; 2000.Carvalho AAF, Carvalho A, Santos Pinto MC. Estudo radiográfico do desenvolvimento da dentição permanente de crianças brasileiras com idade cronológica variando entre 84 e 131 meses. Rev. Odonto UNESP. 1990;19:(1):31-9.Toledo OA. Aspectos da cronologia de erupção dos dentes permanentes. Considerações sobre o efeito da urbanização na alteração da cronologia eruptiva. Rev. Odontol Araçatuba.1965;1:47-64.Loevy HT, Aduss H. Tooth maturation in cleft lip, cleft palate, or both. Cleft Palate J.1988; 25(4):343-47.Ellis III. Management of Patients with Orofacial Clefts. In: Hupp, Ellis III, Tucker. Contemporary oral and maxillofacial surgery, 6ª th. Misssouri: Elsevier; 2014.Freitas e Silva DS, Mauro LDL, Oliveira LB, Ardenghi TM, Bönecker M. Estudo descritivo das fissuras lábio-palatinas relacionadas a fatores individuais, sistêmicos e sociais. RGO. 2008;56(4):387-91.Conway JC, Taub PJ, King R, Oberoi K, Doucette J, Jabs EW. Ten-year experience of more than 35,000 orofacial clefts in Africa. BMC Pediatr. 2015;15:8.Faraj JORA, André M. Alterações dimensionais transversas do arco dentário com fissura labiopalatina, no estágio de dentadura decídua. R Dental Press Ortodon Ortop Facial. 2007; 12(5):100-8.Silva Filho OG, Freitas JAS. Caracterização Morfológica e Origem Embriológica. In: Trindade IEK, Silva Filho OG (orgs). Fissuras labiopalatinas: uma abordagem interdisciplinar. São Paulo: Santos; 2007.p.17-49.Watson ACH. Embriologia, etiologia e incidência. In: Watson ACH, Sell DA, Grunwell P (orgs). Tratamento de fissura labial e fenda palatina. São Paulo: Santos; 2005.p.3-15Lages EMB, Marcos B, Pordeus IA. Oral health of individuals with cleft lip, cleft palate, or both. Cleft Palate-Craniofac J. 2004;41(1):59-63.Zandi M, HeidarI A. An epidemiologic study of orofacial clefts in Hamedan city, Iran: a 15-year study. Cleft Palate–Craniofac J. 2011;48(4 ):483-89.Coutinho ALF, Lima MC, Kitamura MAP, Ferreira Neto J, Pereira RM. Perfil epidemiológico dos portadores de fissuras orofaciais atendidos em um Centro de Referência do Nordeste do Brasil. Rev. Bras Saúde Mater Infant. 2009;9(2):149-56.Tan EL, Yow M, Kuek MC, Wong HC. Dental maturation of unilateral cleft lip and palate. Ann Maxillofac Surg. 2012;2(2):158-62.Lakatos EM, Marconi MA. Fundamentos de metodologia científica. 7 ed. São Paulo: Atlas, 2010.Borodkin AF, Feigal RJ, Beiraghi S, Moller KT, Hodges JS. Permanent tooth development in children with cleft lip and palate. Pediatr Dent. 2008; 30:408-13.Lai MC, King NM, Wong HM. Dental development of Chinese children with cleft lip and palate. Cleft Palate Craniofac J. 2008; 45:289-96.Tan ELY, Kuek MC, Wong HC, Yow M. Longitudinal dental maturation of children with complete unilateral cleft lip and palate: a case-control cohort study.Orthod Craniofac Res.2017; 20(4):189-95.Celebi AA, Ucar FI, Sekerci AE, Caglaroglu M, Tan E. Effects of cleft lip and palate on the development of permanent upper central incisors: a cone-beam computed tomography study. Eur J Orthod. 2015; 37(5):544-49.Ranta R. A comparative study of tooth formation in the permanent dentition of Finnish children with cleft lip and palate. Proc Fin Dent Soc. 1972;68(2):58-66.

scholarly journals PAX7, PAX9 and RYK Expression in Cleft Affected Tissue

Medicina ◽  
2021 ◽  
Vol 57 (10) ◽  
pp. 1075
Author(s):  
Mārtiņš Vaivads ◽  
Ilze Akota ◽  
Māra Pilmane
Keyword(s):  
Cleft Palate ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Rank Correlation ◽  
Control Group ◽  
Orofacial Clefts ◽  
Spearman’S Rank Correlation ◽  
Morphological Studies ◽  
Affected Tissue ◽  
Isolated Cleft Palate

Background and Objectives: Cleft lip with or without cleft palate is one of the most common types of congenital malformations. Transcription factors paired box 7 and 9 (PAX7, PAX9) and receptor-like tyrosine kinase (RYK) have been previously associated with the formation of orofacial clefts but their exact possible involvement and interactions in the tissue of specific cleft types remains uncertain. There is a limited number of morphological studies analyzing these specific factors in cleft affected tissue due to ethical aspects and the limited amount of available tissue material. This study analyses the presence of PAX7, PAX9, and RYK immunopositive structures within different cleft affected tissue to assess their possible involvement in cleft morphopathogenesis. Materials and Methods: Cleft affected tissue was collected from non-syndromic orofacial cleft patients during cleft correcting surgery (36 patients with unilateral cleft lip, 13 patients with bilateral cleft lip, 26 patients with isolated cleft palate). Control group oral cavity tissue was obtained from 7 patients without cleft lip and palate. To evaluate the number of immunopositive structures in the cleft affected tissue and the control group, a semiquantitative counting method was used. Non-parametric statistical methods (Kruskal–Wallis H test, Mann–Whitney U test, and Spearman’s rank correlation) were used. Results: Statistically significant differences for the number of PAX7, PAX9, and RYK-positive cells were notified between the controls and the patient groups. Multiple statistically significant correlations between the factors were found in each cleft affected tissue group. Conclusions: PAX7, PAX9, and RYK have a variable involvement and interaction in postnatal morphopathogenesis of orofacial clefts. PAX7 is more associated with the formation of unilateral cleft lip, while PAX9 relates more towards the isolated cleft palate. The stable presence of RYK in all cleft types indicates its possible participation in different facial cleft formations.

scholarly journals THE SPEECH SOUND ERRORS AND LITERACY SKILLS IN CHILDREN WITH OROFACIAL CLEFTS

2021 ◽  
Vol 71 (6) ◽  
pp. 1976-80
Author(s):  
Arooj Karim Khan ◽  
Aasma Yousaf ◽  
Sharmeen Aslam Tarer ◽  
Rukhsana Kausar
Keyword(s):  
Cleft Palate ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Writing Skills ◽  
Speech Sound ◽  
Sampling Strategy ◽  
Literacy Skills ◽  
P Value ◽  
Orofacial Clefts ◽  
Cross Sectional

Objective: To investigate the speech sound errors and literacy skills in children with orofacial clefts (cleft palate& cleft lip and palate). Study Design: Comparative cross-sectional study. Place and Duration of Study: Centre for Clinical Psychology, University of the Punjab, Lahore, from Mar 2016 to Feb 2017. Methodology: A sample of 42 participants (cleft lip & palate: n=18 and cleft palate: n=24) was collected. Two stage sampling strategy was used. Each child was individually screened through Slosson intelligence test revised checklist of orofacial cleft and diagnostic statistical Manual-V checklist. Then children were provided with assessment measures which included demographic informational questionnaire, community developed VPI Screener, word list for articulation and phonological processes, annual status of education report (ASER) and curriculum-based measurement (Written Expression). Manual SODA (substitution, omission, distortion and addition) analysis was done to know about the type of speech sound errors. Results: Independent sample t-test was used to compare the differences of speech sound errors (52.11 ± 25.08), (47.29 ± 25.38), reading skills (3.67 ± 1.14), (3.75 ± 1.26) and writing skills (14.61 ± 13.49), (25.14 ± 29.16) in cleft lip & palate and cleft palate respectively, indicated that there were no differences; with p-value: p=0.54, 0.83, 0.13. Conclusion: Results indicated no significant differences in speech sound errors, reading, writing skills and resonance between children with cleft lip & palate and cleft palate.

scholarly journals OROFACIAL CLEFTING –AN EXTENSIVE REVIEW

2021 ◽  
Vol 5 (9) ◽  
Author(s):  
T. Ashiq ◽  
Srikrishnan Rajendran Sri Ramkumar ◽  
N. Mugunthan ◽  
R.S. Uma ◽  
Iyyanar Jayaraj ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Cleft Palate ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Clinical Manifestations ◽  
The United States ◽  
World Health ◽  
Upper Respiratory Tract ◽  
Facial Cleft ◽  
Facial Clefts

Groove in the palatal vault makes an abnormal communication between oral and nasal cavity is known as oro-facial cleft. It is an uncommon presentation in day-to-day clinical practice. According to World Health Organization, children with the complaint of oro-facial clefts found to be high in India. Children are commonly suffering from functional and aesthetical problems due to Oro-facial clefting. Globally, an estimated 200,000 babies are born with a cleft lip, palate or both each year in the United States. Etiology may be congenital or acquired. Palatal and Alveolar cleft defects are the most common etiological factors. Cleft lip and cleft palate can sometimes develop in combination with a syndrome due to genetic causes. The acquired causes may be infections, trauma, postsurgical complications, neoplasms, periapical pathology, radio and chemo necrosis. Clinical features like defective speech, and upper respiratory tract and ear infections, fetid odor, bad taste, nasal regurgitation of food are the associated consequences of oro-nasal communication. Therefore, this malformation syndrome is an important public health problem. Many cleft palate and cleft lip develops due to the combination of genetic and environmental factors. There are more than 400 genes linked to formation of cleft lip and palate. Some environmental factors associated with cleft include medications, deficiency of folic acid, and cigarette, drugs or alcohol conception   during pregnancy. In this article we review the anatomy, embryology, epidemiology clinical manifestations and treatment options of the oro-facial cleft Key words: Oro-facial Cleft, Classification, , Anatomy , Embryology, Morphology, Incidence, Congenital Anomaly        

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