QUALITY OF LIFE IN A PATIENT POPULATION WITH THE DIAGNOSIS OF CHRONIC PANCREATITIS

Objective We aimed to describe the clinical characteristics of chronic pancreatitis (CP) and patient quality of life (QOL) in a resource-limited setting. Methods We performed a cross-sectional study including patients with clinical and radiological features of CP. We collected clinical data and assessed QOL using the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire. Results We included 103 patients (median age 44 years, 84 men). Median age at symptom onset was 36 (4–78) years. Around 70% of patients had diabetes mellitus and 62.1% had consumed alcohol; 36 (35%) were current smokers. The mean overall global QOL score was 68.7. Most patients (91.3%) sought treatment from multiple centers. Nineteen (18.5%) had pancreatic stone disease, 38 (36.9%) had persistent abdominal pain (median severity 7.8/10, 59 (57.3%) had steatorrhea, and 56 (54.4%) had jaundice. Poor QOL was significantly associated with weight loss, loss of appetite, and intractable pain. No correlation with age, sex, or alcohol consumption was noted. Conclusion A considerable proportion of patients with CP had troublesome symptoms. Intractable pain, loss of appetite, and weight loss were significantly associated with poor QOL. Further assessment is needed of patients’ psychosocial well-being and its association with QOL.

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PNL19 VALIDATING THE RESTLESS LEGS SYNDROME QUALITY OF LIFE QUESTIONNAIRE (RLSQOL) IN A TRIAL PATIENT POPULATION

Value in Health ◽

10.1016/s1098-3015(10)66125-6 ◽

2004 ◽

Vol 7 (6) ◽

pp. 793 ◽

Cited By ~ 2

Author(s):

L Abetz ◽

R Arbuckle ◽

R Allen ◽

E Mavraki ◽

J Kirsch

Keyword(s):

Quality Of Life ◽

Restless Legs Syndrome ◽

Patient Population ◽

Life Questionnaire ◽

Quality Of Life Questionnaire ◽

Restless Legs

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Strengthening the pharmacological potential of drug therapy in treatment of patients with chronic pancreatitis by using therapeutic physical factors

Fizioterapevt (Physiotherapist) ◽

10.33920/med-14-2012-01 ◽

2020 ◽

pp. 8-14

Author(s):

R. M. Mallaeva ◽

A. N. Makhinko ◽

M. B. Uzdenov

Keyword(s):

Quality Of Life ◽

Chronic Pancreatitis ◽

Drug Therapy ◽

Clinical Manifestations ◽

Medical Rehabilitation ◽

Control Group ◽

Physical Factors ◽

Standard Drug ◽

Pharmacological Potential

The purpose of the study is to improve rehabilitation treatment of patients with chronic pancreatitis (CP) at inpatient stage by strengthening pharmacological potential of drug therapy due to inclusion of therapeutic physical factors (TPF) in therapeutic programs. Materials and methods. 159 patients with acute CP were observed. By simple randomization, 4 groups were formed: the control group (MG, 39 people) received standard drug therapy; 1st comparison group (GC1; 38 people) additionally received TPF; GC2 (40 people) in addition to treatment in GC1 had drinking mineral water «Slavyanovskaya»; in main group (42 people) in addition to the treatment in GC2 got preformed peloidotherapy on the cervical-collar zone. All the patients underwent the evaluation of clinical score and quality of life before and after medical rehabilitation. Results. In MG, clinical symptomatology leveling was by 78,2% (p<0,01), in GC1 — by 71,5% (p<0,01), GC2 — by 62,3% (p<0,01), CG — by 57,2% (p<0,01) on average immediately after the treatment, which was in a clear correlation with indicators of quality of life. In the long term (in 6 and 12 months), the advantage of combination therapy was noted with the same validity, the preservation of the achieved positive result was mostly noted in the MG: after 6 months the improvement in physical health compared to the initial values was noted by 34,4% (p<0,01), after 12 months — by 24,0% (p<0,05); mental — by 32,3% (p<0,01) and 22,5% (p<0,05), respectively. In both comparison groups, positive dynamics was 10–12% lower, and in the control group, after 6 months, there was only a tendency to improve quality of life indicators. Conclusion. The inclusion of TPF in the programs of the inpatient stage of medical rehabilitation of patients with chronic pancreatitis by strengthening the pharmacological potential of drug therapy contributes to the leveling of clinical manifestations (abdominal pain, dyspepsia and diarrhea), the result of which is an improvement in the quality of life of this category of patients.

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Shared Symptoms and Putative Biological Mechanisms in Chronic Liver Disease

Biological Research For Nursing ◽

10.1177/1099800414541541 ◽

2014 ◽

Vol 17 (2) ◽

pp. 222-229 ◽

Cited By ~ 3

Author(s):

Victoria Menzies ◽

Nancy Jallo ◽

Patricia Kinser ◽

Jo Lynne W. Robins ◽

Kyungeh An ◽

...

Keyword(s):

Quality Of Life ◽

Liver Disease ◽

Chronic Liver Disease ◽

Symptom Management ◽

Patient Population ◽

The United States ◽

Chronic Liver ◽

Biological Mechanisms ◽

Management Interventions

Liver disease affects over 25 million people in the United States and, despite advances in medical management resulting in increased survival, a majority of these individuals report multiple co-occurring symptoms that severely impair functioning and quality of life. The purpose of this review is to (1) propose defining these co-occurring symptoms as a symptom cluster of chronic liver disease (CLD), (2) discuss putative underlying biological mechanisms related to CLD, including the liver–gut–brain axis and influence of the microbiome, and (3) discuss the implications for biobehavioral research in this patient population. Biobehavioral research focusing on the interrelated, and possibly synergistic, mechanisms of these symptoms may lead to the development and testing of targeted symptom management interventions for improving function and quality of life in this growing patient population.

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QUALITY OF LIFE IN PATIENTS WITH CHRONIC PANCREATITIS IN THE MOSCOW REGION

Almanac of Clinical Medicine ◽

10.18786/2072-0505-2015-40-64-71 ◽

2016 ◽

pp. 64-71

Author(s):

S. V. Belyakova ◽

E. A. Belousova

Keyword(s):

Quality Of Life ◽

Chronic Pancreatitis ◽

Moscow Region

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Tobacco Smoking and Motivation to Quit in Psychiatric Patients

European Psychiatry ◽

10.1016/s0924-9338(09)70653-4 ◽

2009 ◽

Vol 24 (S1) ◽

pp. 1-1

Author(s):

I. Ganhão ◽

E. Gonçalves ◽

A. Paixão ◽

M. Trigo

Keyword(s):

Quality Of Life ◽

Risk Factors ◽

Patient Population ◽

Psychiatric Patients ◽

Major Health ◽

Smoking Restrictions ◽

Motivation To Quit ◽

Smoking Quantity ◽

Heavy Smokers

Introduction:Smoking is a major health risk in the population in general with significantly increased morbility/mortality with severe consequences on the quality of life and tremendous economic burden on society. It is well known that psychiatric patients have an even higher prevalence of smoking, of heavy smokers and of other risk factors that contribute to the same illnesses.Non-smoking campaigns/smoking restrictions have flourished and it appears that more people are quitting or seriously contemplating the idea. When once, many non-smokers tolerated smokers, today the stigma associated with smoking is undeniable. Psychiatric patients, already greatly stigmatized, risk even becoming more so. Furthermore, smoking cessation programs and interventions frequently are not available, exclude many psychiatric patients and/or are ill-adapted to the special needs in this patient population.Aim:To establish the prevalence of smoking, quantity of tobacco smoked, other factors of dependence by psychiatric diagnosis in a portuguese psychiatric hospital.Establish the motivation of these patients to seek help by professionals and motivation to quit.Methods:Application of questionnaires including Fagerstrom's Modified Questionnaire to patients under care by one team of a Psychaitric hospital in Lisbon, Portugal (CHPL - Sector A).Discussion and conclusions:The study is under way therefore, there are no valid conclusions yet.Certainly it will be possible to confirm high levels of smoking tobacco in this patient population. Hopefully, we may also conclude that there is the desire to change smoking habits making cessation programs a needed and welcomed intervention in psychiatric settings.

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Quality of life comparison in chronic pancreatitis patients: A case-control study

Pancreatology ◽

10.1016/j.pan.2015.05.257 ◽

2015 ◽

Vol 15 (3) ◽

pp. S68 ◽

Cited By ~ 1

Author(s):

Samuel Han ◽

Yoel Carrasquillo ◽

Julien Fahed ◽

Joan Kheder ◽

Wahid Wassef

Keyword(s):

Quality Of Life ◽

Chronic Pancreatitis ◽

Case Control Study ◽

Case Control ◽

Control Study

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A Modern Review of the Operative Management of Chronic Pancreatitis

The American Surgeon ◽

10.1177/000313481007601010 ◽

2010 ◽

Vol 76 (10) ◽

pp. 1071-1074 ◽

Cited By ~ 4

Author(s):

Jonathan C. King ◽

Shannon Abeywardina ◽

James J. Farrell ◽

Howard A. Reber ◽

O. Joe Hines

Keyword(s):

Quality Of Life ◽

Chronic Pancreatitis ◽

Short Form ◽

Operative Management ◽

Poor Quality ◽

Whipple Procedure ◽

Life Questionnaire ◽

Historical Controls

Chronic pancreatitis is a debilitating disease resulting in pain, intestinal malabsorption, endocrine dysfunction, and poor quality of life (QoL). Our aim was to analyze surgical outcomes for patients with chronic pancreatitis. Data for patients undergoing operations for chronic pancreatitis between 1990 and 2009 were reviewed. Demographics, operative and perioperative data, and survival were catalogued. QoL was determined (Short Form 36 and European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire + PAN-26) and compared with historical controls. The mean age was 51 ± 2 years, 38 patients were male (53%), the most common indication was pain (71%), the etiology of pancreatitis often was alcohol, and most patients underwent a Whipple procedure (56%). Operative time was 316 ± 17 minutes and blood loss was 363 ± 75 mL. There were 34 complications in 30 patients (42%) and one death. QoL surveys were administered for 25 of 55 (45%) surviving patients at a mean follow-up of 72 ± 16 months. Mean survival was 99 ± 9 months, whereas 5- and 10-year survival were 86 and 75 per cent. QoL scores were uniformly better than historical controls. Our data demonstrate that operations for chronic pancreatitis can be performed with acceptable morbidity and mortality. Patients have excellent survival and improved QoL compared with historical controls. Surgery is an effective and durable treatment option for patients with chronic pancreatitis.

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