scholarly journals Theological aspects of educational postulates of Ludwika Jeleńska (1885–1961) in the light of contemporary interdisciplinary discourses of theology with education sciences

2021 ◽  
Vol 21 ◽  
Author(s):  
Leszek Waga
Keyword(s):  
Close Association ◽  
Modern Science ◽  
Contemporary Christian

The main purpose of the paper is to present the contemporary perspectives of interdisciplinary discourse between theology and education sciences. The basis of the considerations is the concept of integral pedagogy reconstructed on the basis of the educational postulates presented by a Polish educator, Ludwika Jeleńska (1885–1961). The originality and relevance of this concept is not so much due to the association of education with faith content; it's actually due to the close association of pedagogy with theology, and theory with practice. In Jeleńska's works, theology – in a precursory manner, characteristic of contemporary Christian pedagogy – does not merely act as a normative conveyor of Christian values and ideas, but is an element that inspires the development of modern science and broadly understood culture.

scholarly journals Interventional Efects of the Topical of “Sanse Powder” Essential Oils Nanoemulsion on Knee Osteoarthritis in Rats by Targeting the ERS/TXNIP/NLRP3 Signaling Axis

2021 ◽  
Vol 12 ◽  
Author(s):  
Zixiu Liu ◽  
Taiyang Liao ◽  
Nan Yang ◽  
Liang Ding ◽  
Xiaochen Li ◽  
...  
Keyword(s):  
Essential Oil ◽  
Knee Osteoarthritis ◽  
Close Association ◽  
Modern Science ◽  
Synovial Inflammation ◽  
Signaling Axis ◽  
Traditional Natural ◽  
Effective Drugs

Purpose: Our recent research is dedicated to finding effective drugs for the treatment of knee osteoarthritis (KOA) from traditional Chinese medicine and trying to make full use of modern science and technology to uncover the mechanisms and targets behind them. Synovial inflammation is one of the key pathological features of KOA, and a growing number of researchers realize that early intervention of synovial inflammation may be able to reverse disease progression. The close association of traditional natural products with modern nanotechnology may be important for improving the anti-synovitis efficacy. The purpose of our research was to explore the anti-synovitis mechanism of NEs-SP-EO that might be associated with the ERS/TXNIP/NLRP3 signalling axis.Methods: Chemical composition of “Sanse Powder” essential oil (SP-EO) and NEs-SP-EO were analyzed by GC-MS. NEs-SP-EO were prepared and characterized by nanoparticle tracking analysis, polydispersity index (PDI), zeta potential (ZP), ultraviolet-visible spectroscopy, and transmission electronic microscopy. The CCK8 assay for cell viability of NEs-SP-EO was performed on fibroblast-like synovial cells (FLSs) and the inflammatory environment was stimulated by LPS to explore the therapeutic mechanisms in vitro. Experiments of NEs-SP-EO in vivo were performed in male SD rats.Results: The GC-MS results showed that 30 compounds were present in SP-EO and 11 components of NEs-SP-EO were identified. The results also showed that the formulation of NEs-SP-EO exhibited suitable particle size, negative charge, and stable system. In vitro and vivo testing, NEs-SP-EO produced anti-synovitis efficacy by reduced the induction of the ERS/TXNIP/NLRP3 signaling axis as well as regulating the overproduction of IL-1β, IL-18.Conclusion: We have developed a new type of essential oil nanoemulsion from “Sanse Powder” and demonstrated that it can managing synovitis of KOA. Besides, we have initially explored the anti-inflammatory mechanism that may be related to the ERS/TXNIP/NLRP3 signaling axis.

Immunocytochemical Localization of Amyloid Protein AA in the “Dense Fibrillar Inclusions” of the Reticuloendothelical Cells

1977 ◽  
Vol 35 ◽  
pp. 438-439
Author(s):  
T. Shirahama ◽  
M. Skinner ◽  
A.S. Cohen
Keyword(s):  
Amyloid Fibril ◽  
Close Association ◽  
Gel Filtration ◽  
Fibril Formation ◽  
Amyloid Protein ◽  
Electron Microscopic ◽  
Amyloid Deposits ◽  
Amyloid Fibril Formation ◽  
Electron Microscopic Technique ◽  
Lysosomal System

A1thought the mechanisms of amyloidogenesis have not been entirely clarified, proteolysis of the parent proteins may be one of the important steps in the amyloid fibril formation. Recently, we reported that "dense fibrillar inclusions" (DFI), which had the characteristics of lysosomes and contained organized fibrillar profiles as well, were observed in the reticuloendothelial cells in close association with the foci of new amyloid deposits. We considered the findings as evidence for the involvement of lysosomal system in amyloid fibril formation (l). In the present study, we attempted to determine the identity of the contents of the DFI by the use of antisera against the amyloid protein (AA) and an immuno-electron microscopic technique.Amyloidosis was induced in CBA/J mice by daily injections of casein (l). AA was isolated from amyloid-laden spleens by gel filtration and antibody to it was produced in rabbits (2). For immunocytochemistry, the unlabeled antibody enzyme method (3) was employed.

Linear Arrays of Helical Polyribosomes in Cells Exposed to Antitumor Drug Vincristine Sulfate

1969 ◽  
Vol 27 ◽  
pp. 358-359
Author(s):  
Awtar Krishan
Keyword(s):  
Close Association ◽  
Annulate Lamellae ◽  
Large Array ◽  
Vincristine Sulfate ◽  
Linear Arrays ◽  
Golgi Membranes ◽  
Related Drug ◽  
Drug Leads ◽  
Lethal Doses ◽  
Vinblastine Sulfate

Earle's L-929 fibroblasts treated with mitosis-arresting but sub-lethal doses of vinblastine sulfate (VLB) show hypertrophy of the granular endoplasmic reticulum and annulate lamellae. Exposure of the cells to heavier doses of vincristine sulfate (VCR), a VLB-related drug, leads to the accumulation of large amounts of helical polyribosomes, Golgi membranes and crystals in the cytoplasm. In many of these cells a large number of helical polyribosomes are arranged in prominent linear rows, some of which may be up to 5 micrometers in length. Figure 1 shows a large array of helical polyribosomes near a crystalline mass (CRS) in an Earle's L-929 fibroblast exposed to VCR (5ϒ/ml.) for 3 hours At a higher magnification, as seen in figure 2, the helical polyribosomes are seen arranged in parallel rows. In favorably cut sections, a prominent backbone like "stalk" of finely granular material, measuring approximately 300Å in width is seen in close association with the linear rows of helical polyribosomes.

SEM analysis of fish scale cross sections: A technique study

1992 ◽  
Vol 50 (1) ◽  
pp. 744-745
Author(s):  
M.E. Lee ◽  
A. Moller ◽  
P.S.O. Fouche ◽  
I.G Gaigher
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Cross Sections ◽  
Soft Tissues ◽  
Close Association ◽  
Sem Analysis ◽  
Fish Scale ◽  
Fish Scales ◽  
Micro Structures ◽  
Scanning Electron

Scanning electron microscopy of fish scales has facilitated the application of micro-structures to systematics. Electron microscopy studies have added more information on the structure of the scale and the associated cells, many problems still remain unsolved, because of our incomplete knowledge of the process of calcification. One of the main purposes of these studies has been to study the histology, histochemistry, and ultrastructure of both calcified and decalcified scales, and associated cells, and to obtain more information on the mechanism of calcification in the scales. The study of a calcified scale with the electron microscope is complicated by the difficulty in sectioning this material because of the close association of very hard tissue with very soft tissues. Sections often shatter and blemishes are difficult to avoid. Therefore the aim of this study is firstly to develop techniques for the preparation of cross sections of fish scales for scanning electron microscopy and secondly the application of these techniques for the determination of the structures and calcification of fish scales.

The Rise of Early Modern Science

2003 ◽  
Author(s):  
Toby E. Huff
Keyword(s):  
Early Modern ◽  
Modern Science ◽  
Early Modern Science

The Chemical Works of Faraday in Relation to Modern Science

1892 ◽  
Vol 33 (854supp) ◽  
pp. 13653-13654
Author(s):  
Dewar
Keyword(s):  
Modern Science

"Marketocentric" Economics Is Obsolete

2004 ◽  
pp. 36-49 ◽  
Author(s):  
A. Buzgalin ◽  
A. Kolganov
Keyword(s):  
Economic Theory ◽  
Middle Ages ◽  
Modern Science ◽  
Economic Systems ◽  
Main Mode ◽  
Post Market ◽  
Market Relations ◽  
Post Industrial ◽  
The 19Th Century ◽  
The Universe

The "marketocentric" economic theory is now dominating in modern science (similar to Ptolemeus geocentric model of the Universe in the Middle Ages). But market economy is only one of different types of economic systems which became the main mode of resources allocation and motivation only in the end of the 19th century. Authors point to the necessity of the analysis of both pre-market and post-market relations. Transition towards the post-industrial neoeconomy requires "Copernical revolution" in economic theory, rejection of marketocentric orientation, which has become now not only less fruitful, but also dogmatically dangerous, leading to the conservation and reproduction of "market fundamentalism".

PASTURE ESTABLISHMENT ON EAST COAST NORTH ISLAND HILL COUNTRY

1984 ◽  
pp. 216-218
Author(s):  
B.J. Arnst ◽  
O.L. Park
Keyword(s):  
White Clover ◽  
Carrying Capacity ◽  
Return On Investment ◽  
East Coast ◽  
Close Association ◽  
Development Programme ◽  
Low Fertility ◽  
Stock Management ◽  
Hill Country

Large areas of North Island hill country are producing below potential as a result of low fertility and poor pasture composition. Removal of undesirable species and replacement with a higher producing pasture is essential for increased productivity but is difficult to achieve. A development programme is described where the use of glyphosate in close association with oversowing and stock management has allowed rapid pasture establishment, marked increase in carrying capacity and a quick return on investment. Keywords: Pasture establishment, glyphosate, oversowing, white clover, subdivision, productivity.

Paleoecological study of bottom sediments of the lake Goluboye (Karelian Isthmus) according to the results of diatom analysis

2019 ◽  
pp. 265-269
Author(s):  
Angelina E. Shatalova ◽  
Uriy A. Kublitsky ◽  
Dmitry A. Subetto ◽  
Anna V. Ludikova ◽  
Alar Rosentau ◽  
...  
Keyword(s):  
Baltic Sea ◽  
Bottom Sediments ◽  
Modern Science ◽  
Karelian Isthmus ◽  
The Baltic Sea ◽  
Diatom Analysis ◽  
North West ◽  
The North ◽  
Important Direction ◽  
The Baltic

The study of paleogeography of lakes is an actual and important direction in modern science. As part of the study of lakes in the North-West of the Karelian Isthmus, this analysis will establish the dynamics of salinity of objects, which will allow to reconstruct changes in the level of the Baltic Sea in the Holocene.

Sign in / Sign up

Export Citation Format

Share Document