scholarly journals Study of Molecular Interaction for Antibiotic Drug with Sugar Solutions at Different Temperature

2020 ◽  
Vol 10 (01) ◽  
pp. 170-174 ◽  
Author(s):  
Sundus H. Merza ◽  
Nagham H. Abood ◽  
Ahamed M. Abbas
Keyword(s):  
Aqueous Solutions ◽  
Molar Volume ◽  
Atmospheric Pressure ◽  
Apparent Molar Volume ◽  
Viscosity Data ◽  
Free Energy Of Activation ◽  
Ternary Solutions ◽  
Antibiotic Drug ◽  
Solute Interactions ◽  
Molar Expansibility

The interactions of drug amoxicillin with maltose or galactose solutions with a variation of temperature have been discussed by taking in the volumetric and viscometric procedures. Physical properties [densities (ρ) and viscosities (η)] of amoxicillin (AMOX) aqueous solutions and aqueous solutions of two type saccharides (maltose and galactose 0.05m) have been measured at T = (298.15, 303.15 and 308.15) K under atmospheric pressure. The apparent molar volume (ϕv cm3mole-1) has been evaluated from density data and fitted to a Redlich-Mayer equation. The empirical parameters of the Mayer-Redlich equation and apparent molar volume at infinite dilution Ø°v were explicated in terms of interactions from type solute-solvent and solute–solute interactions. Transfer molar volume ΔtraØ°v for AMOX from water to aqueous maltose and galactose solutions were calculated to comprehend different interactions in the ternary solutions. Limiting apparent molar expansibility (Ø°E) and Hepler’s coefficient was also calculated to indicate the structure making ability of AMOX in the ternary solutions. Jones–Dole coefficient B and A have been calculated from viscosity data by employing the Jones–Dole equation. The free energy of activation of viscous flow per mole of the solute (Δμ°2*) and solvent (Δμ°1*) have been explained on the basis of the Eyring and Feakins equation.

scholarly journals Using Volumetric Method the Study of Molecular Interactions of NSAID (DP) in Water and Water + 1M Urea at Different Temperatures

2021 ◽  
Vol 12 (3) ◽  
pp. 3956-3965
Keyword(s):  
Molar Volume ◽  
Molecular Interactions ◽  
Apparent Molar Volume ◽  
Solvent Interactions ◽  
Different Temperatures ◽  
Solute Interactions ◽  
Hydrotropic Agent ◽  
First Time ◽  
Molar Expansibility ◽  
Experimental Density

Understanding possible interactions of drugs and the factors that command such interactions could be helpful to control their disadvantageous effects upon human health. In this study, volumetric properties for the solution of diclofenac potassium (DP), a non-steroidal anti-inflammatory drug (NSAID), were investigated for the first time to look into its molecular interactions at four different temperatures varying from 298.15 K to 313.15 K at 5 K intervals in water as well as aqueous hydrotropic agent urea (1M) solutions. Experimental density data obtained using a pycnometer have been taken to estimate apparent molar properties, i.e., limiting apparent molar volume (〖V_ɸ〗^0), apparent molar volume (V_ɸ), limiting apparent molar expansibility (〖E_ɸ〗^0) and apparent molar expansibility (E_ɸ). The results obtained were discussed in terms of solute-solvent and solute-solute interactions in the studied systems. The obtained results from volumetric data were explored in terms of the existence of solute-solvent interactions in aqueous systems of drug solutions.

scholarly journals Volumetric and Ultrasonic Velocity Studies of Urea and Thiourea in Aqueous Solution

2018 ◽  
Vol 34 (4) ◽  
pp. 1755-1764 ◽  
Author(s):  
Roksana Khatun ◽  
Rajia Sultana ◽  
Ranjit K. Nath
Keyword(s):  
Molar Volume ◽  
Sound Velocity ◽  
Apparent Molar Volume ◽  
Hydration Number ◽  
Adiabatic Compressibility ◽  
Anomalous Behavior ◽  
Ultrasonic Sound ◽  
Apparent Molar Adiabatic Compressibility ◽  
Solute Interactions ◽  
Molar Expansibility

The observations on the anomalous behavior of urea and the comparison between urea and thiourea in aqueous solutions have been examined by volumetric and ultrasonic sound velocity techniques at different temperature (298.15, 303.15, 308.15, 313.15, 318.15 and 323.15 K) , atmospheric pressure by using a high accuracy vibrating U-tube digital density and ultrasonic sound velocity analyzer. The apparent molar volume (ϕv) & apparent molar adiabatic compressibility (ϕk) have been calculated from experimental density and ultrasonic sound velocity data respectively and limiting apparent molar volume (ϕv0), limiting apparent molar adiabatic compressibility (ϕk0) have been evaluated from apparent molar volume vs. molality plot as intercept. Apparent molar expansibility (ϕE) was determined from apparent molar volume and hydration number (nH) from adiabatic compressibility. The results show very interesting information about strong solute-solvent & solute-solute interactions, and also elaborate the structure making or breaking behavior in the solution mixtures.

scholarly journals ThermodynamicProperties of Nicotinicacid in Dilute HCl and inaqueous NaCl solutions at (293.15, 298.15, 303.15 and 308.15)K

2013 ◽  
Vol 10 (2) ◽  
pp. 432-441 ◽  
Author(s):  
Baghdad Science Journal
Keyword(s):  
Nicotinic Acid ◽  
Molar Volume ◽  
Apparent Molar Volume ◽  
Infinite Dilution ◽  
Viscosity Data ◽  
Free Energies ◽  
Nacl Solution ◽  
Solute Interactions ◽  
Viscosity B Coefficient ◽  
Experimental Density

Apparent molar volume, V?, and viscosity B-coefficient of nicotinc acid in water and in aqueous NaCl solutions have been determined from density and viscosity measurements at (293.15, 298.15, 303.15 and 308.15) K. The experimental density data were evaluated by Masson equation, and the derived, apparent molar volume at infinite dilution, Vo?, and the slope Sv, were interpreted in term of solute-solvent and solute- solute interactions. Transfer apparent molar volumes at infinite dilution of nicotinic acid from water to NaCl solutions at various temperatures have been calculated.The viscosity data have been analyzed using Jones-Dole equation, and the derived parameters, Jones-Dolecoefficient, B,and Falkenhagen coefficient,A, have been also interpreted in terms of solute-solvent and solute-solute interactions respectively. The variation of B coefficient with temperature, (dB/dT), was also determined, the negative values indicate that nicotinic acid in aqueous NaCl solution is structure making. The results were interpreted in terms of complex vitamin-water-co-solute (NaCl) interactions. The free energy, enthalpy, andentropy of activation were calculated using the Nightingale, Benck, and Eyring equations. Free energies of activation of viscous flow ( *1) per mole, and, ( *2) per mole,of solvent and solute, respectively, were also calculated. The effects of soluteson the structure of water were interpreted in terms of viscositiesand the thermodynamic parameters.

Molecular Interactions Investigation of L-Histidine in Water and in Aqueous Citric Acid at Different Temperatures Using Volumetric and Acoustic Methods

2018 ◽  
Vol 232 (3) ◽  
pp. 393-408 ◽  
Author(s):  
Dinesh Kumar ◽  
Shashi Kant Sharma
Keyword(s):  
Citric Acid ◽  
Molar Volume ◽  
Atmospheric Pressure ◽  
Apparent Molar Volume ◽  
Adiabatic Compressibility ◽  
Acid Solutions ◽  
Solvent Interactions ◽  
Intermolecular Free Length ◽  
Acoustic Methods ◽  
Different Temperatures

AbstractDensities,ρand ultrasonic speeds, u of L-histidine (0.02–0.12 mol·kg−1) in water and 0.1 mol·kg−1aqueous citric acid solutions were measured over the temperature range (298.15–313.15) K with interval of 5 K at atmospheric pressure. From these experimental data apparent molar volume ΦV, limiting apparent molar volume ΦVOand the slopeSV, partial molar expansibilities ΦEO, Hepler’s constant, adiabatic compressibilityβ, transfer volume ΦV, trO, intermolecular free length (Lf), specific acoustic impedance (Z) and molar compressibility (W) were calculated. The results are interpreted in terms of solute–solute and solute–solvent interactions in these systems. It has also been observed that L-histidine act as structure maker in water and aqueous citric acid.

Study of Intermolecular Interactions of CTAB with Amino Acids at Different Temperatures: A Multi Technique Approach

2019 ◽  
Vol 233 (2) ◽  
pp. 167-182 ◽  
Author(s):  
Anwar Ali ◽  
Nizamul Haque Ansari ◽  
Ummer Farooq ◽  
Shadma Tasneem ◽  
Firdosa Nabi
Keyword(s):  
Molar Volume ◽  
Intermolecular Interactions ◽  
Cetyltrimethylammonium Bromide ◽  
Complete Characterization ◽  
Viscosity Data ◽  
Viscosity Coefficients ◽  
Free Energy Of Activation ◽  
Different Temperatures ◽  
Amino Acid Solutions

Abstract The densities, ρ, viscosities, η and specific conductivities κ, of (0.0002, 0.0004, 0.0006 and 0.0008 m) CTAB in 0.1 m aqueous valine, leucine and isoleucine were measured at different temperatures. The measured data were used to calculate various useful thermodynamic parameters. A complete characterization of any mixture can be performed by means of these thermodynamic properties. The apparent molar volume, ϕv, partial molar volume, $\phi _v^0$ and partial molar isobaric expansibilities, $\phi _E^0,$ were calculated using density data. The viscosity data were analyzed using Jones–Dole equation to obtain viscosity coefficients, A- and B-, free energy of activation per mole of solvent, Δμ1°∗, and solute, Δμ2°∗, enthalpy, ΔH∗ and entropy, ΔS∗ of activation of viscous flow. Measuring the changes in these properties has been found to be an excellent qualitative and quantitative way to obtain information regarding the molecular structure and intermolecular interactions occurring in these mixtures. Various structure-making/breaking ability of solute (cetyltrimethylammonium bromide) in presence of aqueous amino acid solutions were discussed. In addition, fluorescence study using pyrene as a photophysical probe has been carried out, the results of which support the conclusions obtained from other techniques.

Characterizaton and Volumetric Studies of Magnetite (Fe3O4) Nanofluids at Different Temperatures

2015 ◽  
Vol 37 ◽  
pp. 28-35 ◽  
Author(s):  
Muhammad Asghar Jamal ◽  
Ammar Bin Yousaf ◽  
Muhammad Kaleem Khosa ◽  
Muhammad Usman ◽  
Majid Khan
Keyword(s):  
Particle Size ◽  
Molar Volume ◽  
Atmospheric Pressure ◽  
Apparent Molar Volume ◽  
Isentropic Compressibility ◽  
Size Difference ◽  
Volumetric Properties ◽  
Practical Applications ◽  
Different Temperatures ◽  
Uv Visible

Magnetite nanofluid has been prepared in citric acid based medium. Their stability and polydispersity level have been characterized by UV-visible spectrophotometry.The volumetric properties such as apparent molar volume, partial molar volume and isentropic compressibility of nanofluid have been measured at temperature range from 298.15K to 313.15K at atmospheric pressure. The obtained results were interpreted in terms of particle-particle and particle-fluid interactions, and compared with commercially available magnetite nanofluid in terms of particle size difference. It was observed that the influence of particle size on measured volumetric parameters is significant for any practical applications of fluid flow. The differences in measured quantities were determined qualitatively by considering the state of aggregation / particle size distribution of the nanofluids.

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