scholarly journals ThermodynamicProperties of Nicotinicacid in Dilute HCl and inaqueous NaCl solutions at (293.15, 298.15, 303.15 and 308.15)K

2013 ◽  
Vol 10 (2) ◽  
pp. 432-441 ◽  
Author(s):  
Baghdad Science Journal
Keyword(s):  
Nicotinic Acid ◽  
Molar Volume ◽  
Apparent Molar Volume ◽  
Infinite Dilution ◽  
Viscosity Data ◽  
Free Energies ◽  
Nacl Solution ◽  
Solute Interactions ◽  
Viscosity B Coefficient ◽  
Experimental Density

Apparent molar volume, V?, and viscosity B-coefficient of nicotinc acid in water and in aqueous NaCl solutions have been determined from density and viscosity measurements at (293.15, 298.15, 303.15 and 308.15) K. The experimental density data were evaluated by Masson equation, and the derived, apparent molar volume at infinite dilution, Vo?, and the slope Sv, were interpreted in term of solute-solvent and solute- solute interactions. Transfer apparent molar volumes at infinite dilution of nicotinic acid from water to NaCl solutions at various temperatures have been calculated.The viscosity data have been analyzed using Jones-Dole equation, and the derived parameters, Jones-Dolecoefficient, B,and Falkenhagen coefficient,A, have been also interpreted in terms of solute-solvent and solute-solute interactions respectively. The variation of B coefficient with temperature, (dB/dT), was also determined, the negative values indicate that nicotinic acid in aqueous NaCl solution is structure making. The results were interpreted in terms of complex vitamin-water-co-solute (NaCl) interactions. The free energy, enthalpy, andentropy of activation were calculated using the Nightingale, Benck, and Eyring equations. Free energies of activation of viscous flow ( *1) per mole, and, ( *2) per mole,of solvent and solute, respectively, were also calculated. The effects of soluteson the structure of water were interpreted in terms of viscositiesand the thermodynamic parameters.

scholarly journals Study of Molecular Interaction for Antibiotic Drug with Sugar Solutions at Different Temperature

2020 ◽  
Vol 10 (01) ◽  
pp. 170-174 ◽  
Author(s):  
Sundus H. Merza ◽  
Nagham H. Abood ◽  
Ahamed M. Abbas
Keyword(s):  
Aqueous Solutions ◽  
Molar Volume ◽  
Atmospheric Pressure ◽  
Apparent Molar Volume ◽  
Viscosity Data ◽  
Free Energy Of Activation ◽  
Ternary Solutions ◽  
Antibiotic Drug ◽  
Solute Interactions ◽  
Molar Expansibility

The interactions of drug amoxicillin with maltose or galactose solutions with a variation of temperature have been discussed by taking in the volumetric and viscometric procedures. Physical properties [densities (ρ) and viscosities (η)] of amoxicillin (AMOX) aqueous solutions and aqueous solutions of two type saccharides (maltose and galactose 0.05m) have been measured at T = (298.15, 303.15 and 308.15) K under atmospheric pressure. The apparent molar volume (ϕv cm3mole-1) has been evaluated from density data and fitted to a Redlich-Mayer equation. The empirical parameters of the Mayer-Redlich equation and apparent molar volume at infinite dilution Ø°v were explicated in terms of interactions from type solute-solvent and solute–solute interactions. Transfer molar volume ΔtraØ°v for AMOX from water to aqueous maltose and galactose solutions were calculated to comprehend different interactions in the ternary solutions. Limiting apparent molar expansibility (Ø°E) and Hepler’s coefficient was also calculated to indicate the structure making ability of AMOX in the ternary solutions. Jones–Dole coefficient B and A have been calculated from viscosity data by employing the Jones–Dole equation. The free energy of activation of viscous flow per mole of the solute (Δμ°2*) and solvent (Δμ°1*) have been explained on the basis of the Eyring and Feakins equation.

scholarly journals Using Volumetric Method the Study of Molecular Interactions of NSAID (DP) in Water and Water + 1M Urea at Different Temperatures

2021 ◽  
Vol 12 (3) ◽  
pp. 3956-3965
Keyword(s):  
Molar Volume ◽  
Molecular Interactions ◽  
Apparent Molar Volume ◽  
Solvent Interactions ◽  
Different Temperatures ◽  
Solute Interactions ◽  
Hydrotropic Agent ◽  
First Time ◽  
Molar Expansibility ◽  
Experimental Density

Understanding possible interactions of drugs and the factors that command such interactions could be helpful to control their disadvantageous effects upon human health. In this study, volumetric properties for the solution of diclofenac potassium (DP), a non-steroidal anti-inflammatory drug (NSAID), were investigated for the first time to look into its molecular interactions at four different temperatures varying from 298.15 K to 313.15 K at 5 K intervals in water as well as aqueous hydrotropic agent urea (1M) solutions. Experimental density data obtained using a pycnometer have been taken to estimate apparent molar properties, i.e., limiting apparent molar volume (〖V_ɸ〗^0), apparent molar volume (V_ɸ), limiting apparent molar expansibility (〖E_ɸ〗^0) and apparent molar expansibility (E_ɸ). The results obtained were discussed in terms of solute-solvent and solute-solute interactions in the studied systems. The obtained results from volumetric data were explored in terms of the existence of solute-solvent interactions in aqueous systems of drug solutions.

scholarly journals Apparent molar volume and coefficients of Jones-Dole equation for the evaluation of ion- solvent interactions of barium chloride in aqueous 1, 4-dioxane and ethylene glycol solutions at T= (298.15 K to 313.15) K and at atmospheric pressure

2020 ◽  
Vol 10 (4) ◽  
pp. 5901-5909 ◽  
Keyword(s):  
Ethylene Glycol ◽  
Molar Volume ◽  
Apparent Molar Volume ◽  
Activation Parameters ◽  
Barium Chloride ◽  
State Theory ◽  
Viscosity Data ◽  
Solvent Interactions ◽  
Viscosity B Coefficient ◽  
The Given

The viscosity and density of barium chloride have been measured at T= (298.15-313.15) K in aqueous solutions of 1, 4-Dioxane (1,4-DO) and Ethylene glycol (EG). Jones–Dole equation was used to analyze the viscosity data. The apparent molar volume, V_ϕ limiting apparent molar volume, V_ϕ^0 are calculated from the density data. Limiting apparent molar expansibilities, E_ϕ^0 have been used to describe the temperture dependency of V_ϕ^0. The standard volume of transfer, ΔtV_ϕ^0 and viscosity B-coefficient of transfer, ΔtB of barium chloride from water to aqueous 1, 4-DO and EG solutions were systematizing the different types of interactions in the given solutions. The structure making and breaking capacity of solute in solutions was interpreted with the help of Helper equation. The positive value of (∂2V_ϕ^0/∂T2)p suggests the structure making nature for BaCl2 in given solution. It is observed that Friedman-Krishnan co-sphere model explains the increase in the transfer volume of BaCl2 with an increase in 1,4-DO and EG concentrations. The activation parameters of the viscous flow of the given solutions were calculated and interpreted using transition state theory.

scholarly journals Exploration of Diverse Interactions of Some Vitamins in Aqueous Mixtures of Cysteine

2017 ◽  
Vol 58 (2) ◽  
Author(s):  
Mahendra Nath Roy ◽  
Palash Chakraborti
Keyword(s):  
Apparent Molar Volume ◽  
Adiabatic Compressibility ◽  
Viscosity Data ◽  
Aqueous Mixtures ◽  
Lorenz Equation ◽  
Solvent Interactions ◽  
Solute Interactions ◽  
Viscosity B Coefficient ◽  
Diverse Interactions ◽  
Apparent Molar Adiabatic Compressibilities

The apparent molar volume (<em>Φ<sub>V</sub></em>), viscosity B-coefficient, molal refraction (<em>R</em>) and adiabatic compressibility (<em>Φ<sub>K</sub></em>) of Nicotinic Acid, Ascorbic Acid, and Folic Acid have been determined in 0.01, 0.03, 0.05 mol∙dm<sup>-3</sup> aqueous Cysteine solutions at 298.15 K from density (<em>ρ</em>), viscosity (<em>η</em>), refractive index (<em><em>n<sub>D</sub></em></em>) and speed of sound (<em>u</em>) respectively. The limiting apparent molar volumes (<em>Φ<sup>0</sup><sub>V</sub></em>) and experimental slopes (<em>S*<sub>V</sub></em>), derived from the Masson equation, have been interpreted in terms of solute-solvent and solute-solute interactions respectively. The viscosity data were analyzed using the Jones-Dole equation and the derived parameters <em>A</em> and <em>B</em> have also been interpreted in terms of solute-solute and solute-solvent interactions respectively in the solutions. Using the Lorentz-Lorenz equation, molal refractions (<em>R</em>) have been calculated. At infinite dilution, limiting apparent molar adiabatic compressibilities (<em>Φ<sup>0</sup><sub>K</sub></em>) of these vitamins were evaluated and discussed.

scholarly journals Excess molar volume and isentropic compressibility for binary or ternary ionic liquid systems

2010 ◽  
Author(s):  
◽  
Indra Bahadur
Keyword(s):  
Ethyl Acetate ◽  
Molar Volume ◽  
Apparent Molar Volume ◽  
Infinite Dilution ◽  
Methyl Acetate ◽  
Isentropic Compressibility ◽  
Solvent Interactions ◽  
Binary Solutions ◽  
Pure Solvent ◽  
Experimental Density

The thermodynamic properties of mixtures involving ionic liquids (ILs) with alcohols or alkyl acetate or nitromethane at different temperatures were determined. The ILs used were methyl trioctylammonium bis(trifluoromethylsulfonyl)imide ([MOA]+[Tf2N]-) and 1-butyl-3- methylimidazolium methyl sulphate [BMIM]+[MeSO4]-. The ternary excess molar volumes (�������� E ) for the mixtures {methyl trioctylammonium bis (trifluoromethylsulfonyl)imide + methanol or ethanol + methyl acetate or ethyl acetate}and (1-butyl-3-methylimidazolium methylsulfate + methanol or ethanol or 1-propanol + nitromethane) were calculated from experimental density values, at T = (298.15, 303.15 and 313.15) K and T = 298.15, respectively. The Cibulka equation was used to correlate the ternary excess molar volume data using binary data from literature. The �������� E values for both IL ternary systems were negative at each temperature. The negative contribution of �������� E values are due to the packing effect and/or strong intermolecular interactions (ion-dipole) between the different molecules. The density and speed of sound of the binary solutions ([MOA]+[Tf2N]- + methyl acetate or ethyl acetate or methanol or ethanol), (methanol + methyl acetate or ethyl acetate) and (ethanol + methyl acetate or ethyl acetate) were also measured at T = ( 298.15, 303.15, 308.15 and 313.15) K and at atmospheric pressure. The apparent molar volume, Vφ , and the apparent molar isentropic compressibility, κφ , were evaluated from the experimental density and speed of sound data. A Redlich-Mayer type equation was fitted to the apparent molar volume and apparent molar isentropic compressibility data. The results are discussed in terms of solute-solute, solute- solvent and solvent-solvent interactions. The apparent molar volume and apparent molar isentropic compressibility at infinite dilution, ��φ �� and κφ ��, respectively of the binary solutions have been calculated at each temperature. The ��φ �� values for the binary v systems ([MOA]+[Tf2N]- + methyl acetate or ethyl acetate or methanol or ethanol) and (methanol + methyl acetate or ethyl acetate) and (ethanol + methyl acetate or ethyl acetate) are positive and increase with an increase in temperature. For the (methanol + methyl acetate or ethyl acetate) systems ��φ �� values indicate that the (ion-solvent) interactions are weaker. The κφ �� is both positive and negative. Positive κφ ��, for ([MOA] + [Tf2N]- + ethyl acetate or ethanol), (methanol + ethyl acetate) and (ethanol + methyl acetate or ethyl acetate) can be attributed to the predominance of solvent intrinsic compressibility effect over the effect of penetration of ions of IL or methanol or ethanol. The positive κφ �� values can be interpreted in terms of increase in the compressibility of the solution compared to the pure solvent methyl acetate or ethyl acetate or ethanol. The κφ �� values increase with an increase in temperature. Negative κφ ��, for ([MOA] + [Tf2N]- + methyl acetate or methanol), and (methanol + methyl acetate) can be attributed to the predominance of penetration effect of solvent molecules into the intra-ionic free space of IL or methanol molecules over the effect of their solvent intrinsic compressibility. Negative κφ �� indicate that the solvent surrounding the IL or methanol would present greater resistance to compression than the bulk solvent. The φ �� values decrease with an increase in the temperature. The infinite dilution apparent molar expansibility, ��φ �� , values for the binary systems (IL + methyl acetate or ethyl acetate or methanol or ethanol) and (methanol + methyl acetate or ethyl acetate) and (ethanol + methyl acetate or ethyl acetate) are positive and decrease with an increase in temperature due to the solution volume increasing less rapidly than the pure solvent. For (IL + methyl acetate or ethyl acetate or methanol or ethanol) systems ��φ �� indicates that the interaction between (IL + methyl acetate) is stronger than that of the (IL + ethanol) or (IL + methanol) or (IL + ethyl acetate) solution. For the (methanol + methyl acetate or ethyl acetate) systems ��φ �� values vi indicate that the interactions are stronger than (ethanol + methyl acetate or ethyl acetate) systems.

scholarly journals Mutual Comparison Studies of Mono and Di Cations in Binary and Ternary Aqueous Electrolytes Solution at 298.15 K

2021 ◽  
Vol 2 (1) ◽  
pp. 30-36
Author(s):  
Yasmin Akhtar
Keyword(s):  
Molar Volume ◽  
Apparent Molar Volume ◽  
Viscosity Measurement ◽  
Free Energies ◽  
Solvent Interactions ◽  
Bonding Effect ◽  
Mutual Comparison ◽  
Hydrogen Bonding Effect ◽  
B Coefficients ◽  
Dehydration Effect

Densities and viscosities of binary and ternary electrolytes solution have been determined experimentally at 298.15 K.  The results obtained from density and viscosity measurement have been used to calculate apparent molar volume φv partial molar volume φov at infinite dilution, relative viscosities hrel, A and B coefficients, and free energies of activation of viscous flow of solvent Δ µ10# and solute Δ µ20. The results are discussed in terms of the dehydration effect of the weak ion-ion and strong ion-solvent interactions. The properties of these systems are discussed in terms of the charge, size, and hydrogen bonding effect.

scholarly journals Volumetric and Ultrasonic Velocity Studies of Urea and Thiourea in Aqueous Solution

2018 ◽  
Vol 34 (4) ◽  
pp. 1755-1764 ◽  
Author(s):  
Roksana Khatun ◽  
Rajia Sultana ◽  
Ranjit K. Nath
Keyword(s):  
Molar Volume ◽  
Sound Velocity ◽  
Apparent Molar Volume ◽  
Hydration Number ◽  
Adiabatic Compressibility ◽  
Anomalous Behavior ◽  
Ultrasonic Sound ◽  
Apparent Molar Adiabatic Compressibility ◽  
Solute Interactions ◽  
Molar Expansibility

The observations on the anomalous behavior of urea and the comparison between urea and thiourea in aqueous solutions have been examined by volumetric and ultrasonic sound velocity techniques at different temperature (298.15, 303.15, 308.15, 313.15, 318.15 and 323.15 K) , atmospheric pressure by using a high accuracy vibrating U-tube digital density and ultrasonic sound velocity analyzer. The apparent molar volume (ϕv) & apparent molar adiabatic compressibility (ϕk) have been calculated from experimental density and ultrasonic sound velocity data respectively and limiting apparent molar volume (ϕv0), limiting apparent molar adiabatic compressibility (ϕk0) have been evaluated from apparent molar volume vs. molality plot as intercept. Apparent molar expansibility (ϕE) was determined from apparent molar volume and hydration number (nH) from adiabatic compressibility. The results show very interesting information about strong solute-solvent & solute-solute interactions, and also elaborate the structure making or breaking behavior in the solution mixtures.

Molecular interaction investigation of some alkaline earth metal salts in aqueous citric acid at various temperatures by physiochemical studies

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Manish Kumar ◽  
Shashi Kant ◽  
Deepika Kaushal
Keyword(s):  
Citric Acid ◽  
Molar Volume ◽  
Apparent Molar Volume ◽  
Alkaline Earth ◽  
Relative Viscosity ◽  
Earth Metal ◽  
Metal Salts ◽  
Alkaline Earth Metal ◽  
Viscosity Data ◽  
Metal Chlorides

Abstract Densities, ultrasonic velocity, conductance and viscosity of some alkaline earth metal chlorides such as magnesium chloride (MgCl2) and calcium chloride (CaCl2) were calculated in the concentration range (0.01–0.12 mol kg−1) in 0.01 mol kg−1 aqueous solution of citric acid (CA + H2O) at four varying temperatures T 1 = 303.15 K, T 2 = 308.15 K, T 3 = 313.15 K and T 4 = 318.15 K. The parameters like apparent molar volume (ϕ v ), limiting apparent molar volume ( ϕ v o ${\phi }_{v}^{o}$ ) and transfer volume (Δtr ϕ v o ${\phi }_{v}^{o}$ ) were calculated from density data. Viscosity data have been employed to calculate Falkenhagen coefficient (A), Jone–Dole’s coefficient (B), relative viscosity (η r ), and relaxation time (τ) whereas limiting molar conductance ( Λ m o ${{\Lambda}}_{m}^{o}$ ) has been evaluated from conductance studies. Using these parameters, various type of interactions occurred in the molecules have been discussed. Values of Hepler’s constant (d 2 ϕ v o ${\phi }_{v}^{o}$ /dT 2) p , (dB/dT) and d( Λ m o ${{\Lambda}}_{m}^{o}$ η o )/dT suggests that both MgCl2 and CaCl2 behave as structure breaker in (CA + H2O) system. The positive value of transfer volume exclusively tells about solute–solvent interactions which further indicate that both metal chlorides distort the structure of water and act as structure breaker. These studies are helpful in understanding the nature of interactions occurs in biological systems as CA and metal salts are essential for normal functioning of body.

Determination of solute-solute and solute-solvent interaction of pyrimidine5-carbonitrile in aqueous DMSO at 298.15 K.

2020 ◽  
Vol 10 ◽  
Author(s):  
Jayraj S. Aher ◽  
Anant V. Kardel ◽  
Dnyneshawar D. Lokhande ◽  
Manoj R. Gaware ◽  
Arun M. Bhagare
Keyword(s):  
Molar Volume ◽  
Apparent Molar Volume ◽  
Solvent Interaction ◽  
Solvent Interactions ◽  
Aqueous Dmso ◽  
Viscosity Study ◽  
Solute Interactions ◽  
Semi Empirical ◽  
High Electronegativity

Introduction: In this reported work, we have used 80 % aqueous dimethyl sulphoxide (DMSO) for density and viscosity measurement of pyrimidine-5-carbonitrile at 298.15 K. The obtained experimental results shows that as concentration increases density and viscosity increases. From the results of density and viscosity, we have found apparent molar volume, limiting apparent molar volume, semi-empirical parameters, Falkenhagen coefficients and Jones Dole coefficients. Method: The apparent molar volume and limiting apparent molar volume having negative values indicated electostrictive solvation of ions and weak or absence of ion solvent interactions respectively. Result & Discussion : Falkenhagen coefficients is independent of concentration having positive value has shown strong solute-solute interactions and Jones-Dole coefficients having negative value has shown weak solute-solvent interactions. The strong solute-solute interactions were presents in A-1 as compared to A-2 compound because high electronegativity of oxygen atom. These parameters had given idea about molecular interactions such as solute-solute, solute-solvent and solvent-solvent. Conclusion: We have reported density and viscosity study of 4-amino-2-hydroxy-6-phenylpyrimidine-5-carbonitrile and 4- amino-2-mercapto-6-phenylpyrimidine-5-carbonitrile in 80 % aqueous DMSO solution at 298.15 K temperature. It has been observed that Strong molecular association in A-2 as compared to A-1 due to negative values of Øv.

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