scholarly journals Cervical intra-extradural meningioma with en-plaque, dumbbell-shaped, and an unusual calcified pattern in a young patient

2021 ◽  
Vol 12 ◽  
pp. 454
Author(s):  
Bao Quoc Nguyen ◽  
Duc Duy Tri Tran ◽  
Thuan Cong Dang ◽  
Thi Dang Mai ◽  
Hai Duong Pham ◽  
...  

Background: Most spinal meningiomas primarily grow in the intradural extramedullary location. Epidural meningiomas are uncommon; if detected, they usually coexist with intradural lesions. They inhere more aggressive and invasive characteristics compared with their counterparts inside the dura. Case Description: We report a 22-year-old female who was admitted to the hospital with weakness and numbness in both lower limbs. Her cervical magnetic resonance imaging revealed an en-plaque and dumbbell-shaped lesion located from C5 to C8. After gadolinium injection, the whole mass was enhanced and unveiled two portions: intradural and extradural. The bone window of the computed tomography scan revealed calcification inside the lesion. The patient underwent tumor removal surgery. The pathology findings showed a psammomatous meningioma. After 6 months of surgery, the patient has been able to walk with walkers. Conclusion: We should consider spinal meningioma as a differential diagnosis when encountering an extradural lesion in the cervical region. The optimal surgical treatment for young patient with epidural meningiomas is radical surgery with dura attachment removal.

2021 ◽  
Vol 12 ◽  
pp. 505
Author(s):  
Daniel Buchanan ◽  
Nikolay L. Martirosyan ◽  
Wei Yang ◽  
Russell I. Buchanan

Background: The incidence of spinal meningiomas is 0.33/100000 population, and ossified spinal meningiomas are even less commonly encountered. Case Description: A 64-year-old male presented with a progressive T4-level thoracic myelopathy. MR imaging revealed an intradural extramedullary mass that significantly compressed the spinal cord. The accompanying CT demonstrated hyperdensities within the lesion consistent with punctate calcification vs. ossification (i.e. consistent with histological bone formations within tumor). The patient underwent complete resection of the tumor resulting in a full recovery of neurological function within 6 postoperative weeks. The pathological specimen showed findings consistent with an ossified spinal meningioma. Conclusion: Here, we identified a rare case of an ossified thoracic T4 meningioma occurring in a 64-year-old male.


2021 ◽  
Vol 12 ◽  
pp. 409
Author(s):  
Uma V. Mahajan ◽  
Mohit Patel ◽  
Alia M. Hdeib

Background: Primary spinal tumors are rare and include schwannomas. In the cervical region, these lesions can cause pain, radiculopathy, and/or myelopathy. Case Description: A 53-year-old male presented with 9 months of chronic neck pain and left upper extremity radiculopathy/myelopathy. The MRI revealed an intradural extramedullary C6-C7 mass left-sided mass with foraminal extension. Following a C5-C7 laminectomy with C5-T2 instrumented fusion, the diagnosis of schwannoma with evidence of recent hemorrhage was confirmed by biopsy. Three weeks postoperatively, the patient was pain free, no longer taking opioids, and neurologically intact. Although the MR 6 months later showed no tumor, the MRI 15 months later documented a recurrent enhancing C6-C7 lesion. The patient elected to be treated with external beam radiotherapy and remained asymptomatic. Conclusion: A 53-year-old underwent resection of a cervical C6-C7 schwannoma with intratumoral hemorrhage. Fifteen months following C5-C7 laminectomy with C5-T2 fusion, the tumor recurred and required external beam radiation therapy.


2019 ◽  
Vol 67 (6) ◽  
pp. 1543
Author(s):  
Ketan Desai ◽  
AnshuC Warade ◽  
AshishK Jha ◽  
Sanjeev Pattankar ◽  
Chitra Madiwale ◽  
...  

2006 ◽  
Vol 5 (1) ◽  
pp. 76-78 ◽  
Author(s):  
Eric M. Horn ◽  
Vivek R. Deshmukh ◽  
Gregory P. Lekovic ◽  
Curtis A. Dickman

✓ The management of spinal meningiomas with extensive involvement of the dura mater is controversial. The principal difficulty in performing a resection is the potential for complications associated with this approach. The authors present the case of a pregnant 35-year-old woman in whom bilateral lower-extremity numbness, weakness, gait ataxia, and myelopathy developed. Magnetic resonance imaging showed a recurrent thoracic meningioma with extensive infiltration of the dura mater. Durectomy, complete resection, and reconstruction were performed. The patient has not experienced a recurrence 21 months after her treatment. This case illustrates that thoracic spinal meningiomas with extensive dural involvement can be resected safely with a complete durectomy. The novel dural reconstruction involving the implantation of a fascia lata and bovine pericardium allograft is an effective way to reconstruct the dura to create an adequate barrier to cerebrospinal fluid.


2016 ◽  
Vol 7 (01) ◽  
pp. 125-127 ◽  
Author(s):  
Sharad Pandey ◽  
Kulwant Singh ◽  
Vivek Sharma ◽  
Amrita Ghosh ◽  
Saurabh Suman

ABSTRACTMeningiomas are benign in nature and arise from the arachnoid cells. They are mostly situated in the intracranial compartment, whereas spinal meningiomas are rare. Approximately, in 10% of cases, an extradural component is seen but an exclusively extradural meningioma is quite uncommon. However, WHO Grade II (atypical) and Grade III (anaplastic) tumors can behave aggressively. We reported a case of purely extradural psammomatous meningioma in an adult male affecting the dorsal spine although uncommon meningiomas should be included in the differential diagnosis of extradural intraspinal masses.


2019 ◽  
Vol 1 (Supplement_2) ◽  
pp. ii38-ii38
Author(s):  
Yuki Takeshima ◽  
Tatsuya Takezaki ◽  
Tadashi Hamasaki ◽  
Seiji Tajiri ◽  
Akitake Mukasa

Abstract Schwannomas are the most common intradural extramedullary spinal tumors. However, they are usually solid tumors, and totally cystic changes are rare. Herein, we report a case of a 46-year-old male presenting with numbness of right limbs, right hemiplegia, and posterior neck pain for one year. MRI revealed a well-defined cystic long-segment, from C1 to C6, intradural extramedullary mass. The lesion showed hypointense on T1WI, hyperintense on T2WI, hyperintense on DWI, and it was marginally enhanced on the contrast image with Gd-DTPA. C1 laminectomy and hemi-laminectomy from C2 to C6 was performed for tumor resection. The tumor was found to be totally cystic and tensed with a jelly-like content. It was completely resected with the attachment of the C3 dorsal root. Histopathological examination confirmed it to be a schwannoma. The mechanism of cyst formation in schwannoma is considered as results of ischemic necrosis associated with tumor growth, or cystosis due to degeneration of Antoni-type B region. The long-segment, totally cystic intradural cervical schwannoma is rare, bit it should be included in the differential diagnosis of a cystic mass in the spinal region. It can be difficult to distinguish cystic spinal schwannomas from other cystic lesions like arachnoid cyst, epidermoid cyst, and neurenteric cyst. Contrast enhanced MRI is useful by enhancing the margin of the tumor.


2020 ◽  
Vol 1 (4) ◽  
Author(s):  
Dra. Marcela Cherner Kevorkian ◽  
Dra. Inmaculada Navarro Hidalgo ◽  
Dr. Severino Rey Nodar ◽  
Dra. Belén Roig Espert

Ectopic Cushing syndrome is an infrequent cause of hypercortisolism characterized by the secretion of adrenocorticotropic hormone (ACTH) by tumors with neuroendocrine differentiation, such as small cell carcinoma of the lung, bronchial carcinoid, medullary carcinoma thyroid, thymic carcinoma and pancreatic neuroendocrine tumors, among others. The ACTH-dependent Cushing syndrome due to an ectopic tumor accounts for approximately 15% of endogenous Cushing syndrome and, depending on the aggressiveness of the tumor, the manifestations of hypercortisolism may be evident or not. We report a 61-year-old man who consulted for edema of the face and lower limbs, asthenia and cutaneous herpes zoster in the cervical region which during the clinical-radiological studies was diagnoses of two large retroperitoneal masses histologically corresponding to an ACTH-producing neuroendocrine tumor. Key words: Cushing's syndrome, ectopic ACTH, neuroendocrine tumor


Neurosurgery ◽  
1989 ◽  
Vol 25 (2) ◽  
pp. 153-160 ◽  
Author(s):  
Carlo L. Solero ◽  
Maurizio Fornari ◽  
Sergio Giombini ◽  
Giovanni Lasio ◽  
Giuseppe Oliveri ◽  
...  

Abstract The long-term results obtained in a series of 174 patients operated on for spinal meningiomas are critically analyzed. This series was similar to those of other authors with regard to age, sex, location of the tumors, and clinical presentation. Before surgery, about 70% of the patients were included in Groups I and II (mild neurological impairment), and about 30% of the patients were classified in Groups III and IV (significant to severe neurological impairment, up to paraplegia). Complete tumor removal was achieved in 96.5% of the patients, and surgical mortality was about 1%. Microsurgical technique, which was adopted in the last 29 cases, proved to be very effective in reducing undue damage to the spinal cord and in minimizing the postoperative neurological deficits. Of the 174 patients who underwent surgery, 156 underwent late follow-up study for an average of 15 years (2 patients died in the immediate postoperative period, and 16 patients were lost to follow-up). Twenty-nine patients died of causes unrelated to the spinal meningioma; of the remaining 126 patients, 92% were categorized in Groups I and II, and only 8% in Groups III and IV. The rate of recurrence was 6% (9 patients) among the 150 patients who had complete tumor removal, and the rate of regrowth was 17% (1 patient with anaplastic meningioma) among the 6 patients treated by subtotal removal. The early diagnosis of the disease and the use of microsurgical technique appeared as the most relevant factors for further improvement of the surgical results.


2021 ◽  
Author(s):  
Tulio Marcos Coimbra ◽  
Sara Terrim ◽  
Guilherme Diogo Silva

Context: Acute flaccid paralysis (AFP) is characterized by progressive weakness with signs of impairment of the lower motoneuron. Secondary hyperkalemic paralysis is a cause of AFP that must be quickly recognized to prevent cardiac and neurological deterioration. Case report: We present a 69-years-old man admitted to the emergency department due to hyperacute weakness. The patient walked normally to the hospital’s laboratory, where he sat down to wait for the collection of laboratory exams for the investigation of a thrombocytopenia. He was unable to get up from his chair when he was asked to collect the exams. The neurological examination showed symmetrical tetraparesis. Weakness was proximal grade II and distal grade III in the lower limbs. Upper limb weakness was grade IV. Reflexes were abolished in lower limbs and hypoactive in upper limbs. The sensitivity and cranial pairs were normal. Our patient denied bladder or bowel complaints. He also presented intense fasciculations in the cervical region and in the proximal muscles of the upper limbs. Initial laboratory showed potassium of 9.3 mEq/dL. The correction of hyperkalemia led to a complete reversal of weakness and fasciculations. During hospitalization, the patient was diagnosed with systemic lupus erythematosus. Renal impairment led to hyperkalemia. Conclusions: Characterization of the motor examination, sensitivity and of reflexes allow the topographic diagnosis in AFPs. Secondary hyperkalemic paralysis manifests as symmetrical tetraparesis with a proximal predominance with hypoactive and abolished reflexes. Sensory examination is normal. The hyperacute manifestation and the presence of fasciculations reinforce this diagnosis as the cause of AFP.


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