scholarly journals The use of lenticular tissue in corneal refractive surgery

2021 ◽  
pp. 68-72
Author(s):  
S.V. Kostenev ◽  
◽  
S.A. Borzenok ◽  
V.G. Lee ◽  
P.O. Nosirov ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Key Words ◽  
Refractive Surgery ◽  
Future Research ◽  
Corneal Tissue ◽  
Corneal Perforation ◽  
The Future ◽  
Corneal Refractive Surgery

Purpose. To identify the problems of using lenticular tissue, its storage, obtaining cell-free scaffolds in corneal tissue engineering, and the possibility of predicting refraction. The unique advantage of Relex Smile technology is that it is a potentially reversible procedure that allows preserve the extracted lenticules and opens up broad possibilities for the use of lenticules in ophthalmic practice in the future. Research in this area demonstrated the potential for implanted autologous and allogeneic lenticules after creating an intracorneal pocket for treating diseases such as presbyopia, corneal perforation, corneal keratectasia, progressive pterygium, progressive keratoconus. In addition, this article presents the results of recent studies describing protocols for cryopreservation and decellularization of lenticules as the most promising methods in tissue engineering in conditions a shortage of donor's cornea. Key words: Relex Smile, lenticule, implantation, cryopreservation, decellularization, tissue engineering.

scholarly journals COVID-19 Contact Tracing Applications: Design and Operations

2021 ◽  
Vol 11 (4) ◽  
pp. 1-11
Author(s):  
Pulkit Verma ◽  
Neeraj Kumar
Keyword(s):  
Key Words ◽  
Open Source ◽  
Information Storage ◽  
Contact Tracing ◽  
Handheld Devices ◽  
Future Research ◽  
Digital Footprint ◽  
The Future ◽  
Security Concerns ◽  
Made In

The Digital footprint we create in our modern lives through hour handheld devices and wearable gadgets is enormous. It was little known that, in the light of the recent outburst of the pandemic, this digital footprint would play an important role in contact tracing of the infected patients. This digital encounter tracing came into existence in order to relieve the Heath Authorities from the burden of manually tracking the contacts. Different countries developed a number of contact tracing apps based on the different architectures for the same purpose. This paper analyses the different intricacies of the architectures currently in use from the perspective of information storage, division of processing, capabilities and possible security concerns. Effort has been made in order to touch upon the possible attacks in each of the architectures. The paper concludes with the future research efforts in possible optimization of the architecture and the protocols, which in turn may lead to better contact tracing and containment of pandemic. Key words: Digital Proximity, Contact Tracing, Bluetooth, GPS, DP, encryption, Anonymized, Decentralized, Open Source, PACT, DESIRE.

scholarly journals Time-varying regularity of changes in biomechanical properties of the corneas after removal of anterior corneal tissue

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Di Zhang ◽  
Xiao Qin ◽  
Haixia Zhang ◽  
Lin Li
Keyword(s):  
Elastic Modulus ◽  
Stress Relaxation ◽  
Refractive Surgery ◽  
Biomechanical Properties ◽  
Collagen Fibrils ◽  
Uniaxial Tensile ◽  
Control Group ◽  
Corneal Tissue ◽  
Corneal Refractive Surgery ◽  
Corneal Biomechanical Properties

Abstract Background The corneal biomechanical properties with the prolongation of time after corneal refractive surgery are important for providing a mechanical basis for the occurrence of clinical phenomena such as iatrogenic keratectasia and refractive regression. The aim of this study was to explore the changes of corneal elastic modulus, and stress relaxation properties from the 6-month follow-up observations of rabbits after a removal of anterior corneal tissue in simulation to corneal refractive surgery. Methods The anterior corneal tissue, 6 mm in diameter and 30–50% of the original corneal thickness, the left eye of the rabbit was removed, and the right eye was kept as the control. The rabbits were normally raised and nursed for 6 months, during which corneal morphology data, and both of corneal hysteresis (CH) and corneal resistance factor (CRF) were gathered. Uniaxial tensile tests of corneal strips were performed at months 1, 3, and 6 from 7 animals, and corneal collagen fibrils were observed at months 1, 3, and 6 from 1 rabbit, respectively. Results Compared with the control group, there were statistical differences in the curvature radius at week 2 and month 3, and both CH and CRF at months 1, 2, and 6 in experiment group; there were statistical differences in elastic modulus at 1, 3, and month 6, and stress relaxation degree at month 3 in experiment group. The differences in corneal elastic modulus, stress relaxation degree and the total number of collagen fibrils between experiment and control groups varied gradually with time, and showed significant changes at the 3rd month after the treatment. Conclusions Corneas after a removal of anterior corneal tissue undergo dynamic changes in corneal morphology and biomechanical properties. The first 3 months after treatment could be a critical period. The variation of corneal biomechanical properties is worth considering in predicting corneal deformation after a removal of anterior corneal tissue.

scholarly journals Research Progress of the Application of Hypothermia in the Eye

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Lei Xi
Keyword(s):  
Low Temperature ◽  
Allergic Conjunctivitis ◽  
Refractive Surgery ◽  
Retinal Ischemia ◽  
Nerve Tissue ◽  
Research Progress ◽  
Corneal Transplant ◽  
Corneal Tissue ◽  
Ophthalmic Surgery ◽  
Corneal Refractive Surgery

Hypothermia is widely used in the medical field to protect organs or tissues from damage. Different research fields have different explanations of the protection mechanism of hypothermia. Hypothermia is also widely used in the field of ophthalmology, for example, in the eye bank, the preservation of corneal tissue and the preservation of the eyeball. Low temperature can also be applied to some ophthalmic diseases, such as allergic conjunctivitis, retinal ischemia, and retinal hypoxia. It is used to relieve eye symptoms or reduce tissue damage. Hypothermic techniques have important applications in ophthalmic surgery, such as corneal refractive surgery, vitrectomy surgery, and ciliary body cryotherapy for end-stage glaucoma. Hypothermia can reduce the inflammation of the cornea and protect the retinal tissue. The eyeball is a complex organ, including collagen tissue of the eyeball wall and retinal nerve tissue and retinal blood vessels. The mechanism of low temperature protecting eye tissue is complicated. It is important to understand the mechanism of hypothermia and its applications in ophthalmology. This review introduces the mechanism of hypothermia and its application in the eye banks, eye diseases (allergic conjunctivitis, retinal ischemia, and hypoxia), and eye surgeries (corneal transplant surgery, corneal refractive surgery, and vitrectomy).

The Designment of Double-Roll Cake Breaker

2013 ◽  
Vol 734-737 ◽  
pp. 2694-2698
Author(s):  
Ke Qiang Yu
Keyword(s):  
Key Words ◽  
Structural Design ◽  
Theoretical Foundation ◽  
Future Research ◽  
Actual Situation ◽  
The Future ◽  
Soybean Cake ◽  
Efficient Processing ◽  
Soybean Processing

This paper combined the actual situation of crushed soybean processing, for the The double-roll cake breaker and structural design of the shafts, gears, gear plate and flexible institutions were discussed and final using UG software animation simulation,Provides a theoretical foundation for the future research for efficient processing of soybean cake breaker. Key words: double-roller, cake breaker,design.

scholarly journals The Effect of Corneal Refractive Surgery on Glaucoma

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Vassilios Kozobolis ◽  
Aristeidis Konstantinidis ◽  
Haris Sideroudi ◽  
G. Labiris
Keyword(s):  
Refractive Surgery ◽  
Anterior Segment ◽  
Cataract Extraction ◽  
Posterior Pole ◽  
Imaging Modalities ◽  
Glaucomatous Patient ◽  
Need For Treatment ◽  
The Future ◽  
Corneal Refractive Surgery

Laser-assisted refractive procedures have become very popular in the last two decades. As a result, a “generation” of patients with altered corneal properties is emerging. These patients will require both cataract extraction and glaucoma follow-up in the future. Since the glaucoma examination largely depends on the corneal properties, the reshaped postrefractive surgery cornea poses a challenge in the diagnosis, follow-up, and management of the glaucomatous patient. In order to overcome this problem, every patient who is planned to undergo corneal refractive surgery must have a thorough glaucoma examination in order for the ophthalmologist to be able to monitor their patients for possible glaucoma development and/or progression. Some examinations such as tonometry are largely affected by the corneal properties, while others such as the evaluation of the structures of the posterior pole remain unaffected. However, the new imaging modalities of the anterior segment in combination with the most recent advances in tonometry can accurately assess the risk for glaucoma and the need for treatment.

Current Postvention Research and Priorities for the Future

Crisis ◽  
2017 ◽  
Vol 38 (3) ◽  
pp. 202-206 ◽  
Author(s):  
Karl Andriessen ◽  
Dolores Angela Castelli Dransart ◽  
Julie Cerel ◽  
Myfanwy Maple
Keyword(s):  
Social Life ◽  
Online Survey ◽  
Research Priorities ◽  
Future Research ◽  
Physical And Mental Health ◽  
Intercultural Collaboration ◽  
The Social ◽  
The Future ◽  
Suicide Bereavement ◽  
Ethical Approval

Abstract. Background: Suicide can have a lasting impact on the social life as well as the physical and mental health of the bereaved. Targeted research is needed to better understand the nature of suicide bereavement and the effectiveness of support. Aims: To take stock of ongoing studies, and to inquire about future research priorities regarding suicide bereavement and postvention. Method: In March 2015, an online survey was widely disseminated in the suicidology community. Results: The questionnaire was accessed 77 times, and 22 records were included in the analysis. The respondents provided valuable information regarding current research projects and recommendations for the future. Limitations: Bearing in mind the modest number of replies, all from respondents in Westernized countries, it is not known how representative the findings are. Conclusion: The survey generated three strategies for future postvention research: increase intercultural collaboration, increase theory-driven research, and build bonds between research and practice. Future surveys should include experiences with obtaining research grants and ethical approval for postvention studies.

The Knowledge Creation Organization: The Case of Alphana

2012 ◽  
pp. 78-90
Author(s):  
Thang Nguyen Ngoc
Keyword(s):  
Competitive Advantage ◽  
Knowledge Creation ◽  
Future Research ◽  
Sustainable Competitive Advantage ◽  
Knowledge Based ◽  
The Future

Knowledge and the capability to create and utilize knowledge today are consid- ered to be the most important sources of a firm’s sustainable competitive advantage. This paper aims to advance understanding of the knowledge creation of firm in Vietnam by studying Alphanam Company. The case illustrates how knowledge- based management pursues a vision for the future based on ideals that consider the relationships of people in society. The finding shows that the case succeeded because of their flexibility and mobility to keep meeting to the changing needs of the customers or stakeholders. The paper also provided some suggestions for future research to examine knowledge-based management of the companies in a different industry segments and companies originating in other countries

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