The Value Of Computer Perimetry In Determining Tolerant Intraocular Pressure In Juvenile Glaucoma In Combination With High Degree Myopia

2020 ◽  
pp. 97-98
Author(s):  
A.M. Iuldashev ◽  
Keyword(s):  
Intraocular Pressure ◽  
Juvenile Glaucoma ◽  
High Degree

scholarly journals Twenty-Years of Experience in Childhood Glaucoma Surgery

2021 ◽  
Vol 10 (24) ◽  
pp. 5720
Author(s):  
Felix Mathias Wagner ◽  
Alexander Karl-Georg Schuster ◽  
Franz Grehn ◽  
Lukas Urbanek ◽  
Norbert Pfeiffer ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Medical Center ◽  
Glaucoma Surgery ◽  
Congenital Glaucoma ◽  
Surgical Interventions ◽  
Surgical Success ◽  
Different Types ◽  
Juvenile Glaucoma

To quantify the results of childhood glaucoma treatment over time in a cohort of children with different types of childhood glaucoma. A retrospective cohort study of consecutive cases involving children with primary congenital glaucoma, primary juvenile, and secondary juvenile glaucoma at the Childhood Glaucoma Center, University Medical Center Mainz, Germany from 1995 to 2015 was conducted. The main outcome measure was the long-term development of intraocular pressure. Further parameters such as surgical success, refraction, corneal diameter, axial length, and surgical procedure in children with different types of childhood glaucoma were evaluated. Surgical success was defined as IOP < 21 mmHg in eyes without a need for further intervention for pressure reduction. A total of 93 glaucomatous eyes of 61 childhood glaucoma patients with a mean age of 3.7 ± 5.1 years were included. The overall mean intraocular pressure at first visit was 32.8 ± 10.2 mmHg and decreased to 15.5 ± 7.3 mmHg at the last visit. In the median follow-up time of 78.2 months, 271 surgical interventions were performed (130 of these were cyclophotocoagulations). Many (61.9%) of the eyes that underwent surgery achieved complete surgical success without additional medication. Qualified surgical success (with or without additional medication) was reached by 84.5% of the eyes.

scholarly journals Hubungan antara Panjang Aksial Bola Mata dan Derajat Miopia dengan Tekanan Intraokular

2020 ◽  
Vol 4 (1) ◽  
pp. 13-18
Author(s):  
Bella Aliviana
Keyword(s):  
Intraocular Pressure ◽  
Axial Length ◽  
Open Angle Glaucoma ◽  
Pearson Correlation ◽  
Sampling Technique ◽  
Cross Sectional ◽  
Correlation Test ◽  
Pearson Correlation Test ◽  
Cross Sectional Design ◽  
High Degree

Some studies reported that myopia especially high myopia has long axial length. This condition showed with higher intraocular pressure (IOP) and become one of the risk factor of primary open angle glaucoma. However, some other studies reported axial length and degree of myopia don’t have any correlation with intraocular pressure. This study aims to determine whether there is a relationship between the axial length of the eyeball and the degree of myopia with intraocular pressure at Sumatera Eye Center (SMEC), Samarinda. This study began on November to Desember 2019. This research method was analytic research with cross sectional design. The sample in this study was 91 eyes using a purposive sampling technique. Analyzes were performed with the Pearson Correlation test. The result showed the age of IOP increased at 31, 32, and 33 years old, respectively 1 eye. Pearson correlation test showed that IOP did not seem to have any correlation with the axial length, low myopia and high degree of myopia. But, IOP have correlation with moderate myopia (r=0,019).

scholarly journals Transpalpebral tonometry after penetrating keratoplasty

2020 ◽  
Vol 20 (4) ◽  
pp. 175-179
Author(s):  
E.V. Karlova ◽  
◽  
A.V. Zolotarev ◽  
E.S. Milyudin ◽  
A.E. Pershakova ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Penetrating Keratoplasty ◽  
Early Postoperative Period ◽  
Second Step ◽  
Negative Effects ◽  
Transpalpebral Tonometry ◽  
Applanation Tonometer ◽  
Iop Measurement ◽  
High Degree ◽  
High Repeatability

Aim: to assess the efficacy and safety of EASYTON transpalpebral intraocular pressure (IOP) tonometer in the early postoperative period after penetrating keratoplasty (PK).Patients and Methods: 43 patients after unilateral PK were enrolled. IOP measurements with palpation and EASYTON transpalpebral IOP tonometer in the operated eye were performed daily for 7 days. In addition, IOP measurements with palpation, EASYTON, and the Goldmann applanation tonometer (GAT) in the fellow (non-operated) eye were performed.Results: Bland-Altman plots demonstrated a rather high degree of the similarity of IOP measurements with palpation, GAT, and EASYTON in the non-operated eyes. Therefore, IOP measurement by palpation is a rather informative technique and can be used to compare the accuracy of EASYTON in the operated eyes of the same patients. During the second step, a high degree of the similarity of IOP measurements with palpation and EASYTON was demonstrated in the operated eyes after PK. Mean IOP spread (as demonstrated by three consecutive IOP measurements with EASYTON) was 1.32 mm Hg thus showing a high degree of repeatability. The lack of the negative effects of IOP measurements with EASYTON supports its safety.Conclusion: EASYTON transpalpebral IOP tonometer prevents the subjectivity of IOP measurements after PK and makes tonometry available to the general public. The lack of the contact with the cornea, a rather high accuracy, a high repeatability, and the lack of negative effects allow for using this device after PK.Keywords: transpalpebral IOP tonometer, intraocular pressure, penetrating keratoplasty, instrumental tonometry, EASYTON, non-contact tonometry.For citation: Karlova E.V., Zolotarev A.V., Milyudin E.S., Pershakova A.E. Transpalpebral tonometry after penetrating keratoplasty. Russian Journal of Clinical Ophthalmology. 2020;20(4):175–179. DOI: 10.32364/2311-7729-2020-20-4-175-179.

Tissue section lifting for electron microscopy

1978 ◽  
Vol 36 (2) ◽  
pp. 86-87
Author(s):  
Adrian F. van Dellen
Keyword(s):  
Infectious Disease ◽  
Electron Microscopy ◽  
Tissue Culture ◽  
Organ System ◽  
Surrounding Tissue ◽  
Paraffin Sections ◽  
Surface Areas ◽  
Specific Determination ◽  
High Degree ◽  
Accuracy And Repeatability

The morphologic pathologist may require information on the ultrastructure of a non-specific lesion seen under the light microscope before he can make a specific determination. Such lesions, when caused by infectious disease agents, may be sparsely distributed in any organ system. Tissue culture systems, too, may only have widely dispersed foci suitable for ultrastructural study. In these situations, when only a few, small foci in large tissue areas are useful for electron microscopy, it is advantageous to employ a methodology which rapidly selects a single tissue focus that is expected to yield beneficial ultrastructural data from amongst the surrounding tissue. This is in essence what "LIFTING" accomplishes. We have developed LIFTING to a high degree of accuracy and repeatability utilizing the Microlift (Fig 1), and have successfully applied it to tissue culture monolayers, histologic paraffin sections, and tissue blocks with large surface areas that had been initially fixed for either light or electron microscopy.

Electron Microscopy in Molecular Biology

1967 ◽  
Vol 25 ◽  
pp. 2-3
Author(s):  
Cecil E. Hall
Keyword(s):  
Electron Microscopy ◽  
Molecular Biology ◽  
Noise Level ◽  
Molecular Structures ◽  
Material Structure ◽  
The Arts ◽  
Shadow Casting ◽  
Electron Image ◽  
High Degree ◽  
Very High

The visualization of organic macromolecules such as proteins, nucleic acids, viruses and virus components has reached its high degree of effectiveness owing to refinements and reliability of instruments and to the invention of methods for enhancing the structure of these materials within the electron image. The latter techniques have been most important because what can be seen depends upon the molecular and atomic character of the object as modified which is rarely evident in the pristine material. Structure may thus be displayed by the arts of positive and negative staining, shadow casting, replication and other techniques. Enhancement of contrast, which delineates bounds of isolated macromolecules has been effected progressively over the years as illustrated in Figs. 1, 2, 3 and 4 by these methods. We now look to the future wondering what other visions are waiting to be seen. The instrument designers will need to exact from the arts of fabrication the performance that theory has prescribed as well as methods for phase and interference contrast with explorations of the potentialities of very high and very low voltages. Chemistry must play an increasingly important part in future progress by providing specific stain molecules of high visibility, substrates of vanishing “noise” level and means for preservation of molecular structures that usually exist in a solvated condition.

A High Angle, Double Tilting Cold Stage for the AEI EM7

1974 ◽  
Vol 32 ◽  
pp. 450-451
Author(s):  
P.R. Swann ◽  
A.E. Lloyd
Keyword(s):  
Habit Plane ◽  
Temperature Control ◽  
Tilt Angle ◽  
Cooling System ◽  
Thermal Drift ◽  
High Angle ◽  
Cold Stage ◽  
High Degree ◽  
Better Than

Figure 1 shows the design of a specimen stage used for the in situ observation of phase transformations in the temperature range between ambient and −160°C. The design has the following features a high degree of specimen stability during tilting linear tilt actuation about two orthogonal axes for accurate control of tilt angle read-out high angle tilt range for stereo work and habit plane determination simple, robust construction temperature control of better than ±0.5°C minimum thermal drift and transmission of vibration from the cooling system.

New Aspects in the Design of Electron Optical Magnification Systems

1972 ◽  
Vol 30 ◽  
pp. 606-607
Author(s):  
Willem H.J. Andersen
Keyword(s):  
Electron Microscope ◽  
Imaging System ◽  
Chromatic Aberration ◽  
Research Tool ◽  
Energy Losses ◽  
Objective Lens ◽  
Theoretical Limit ◽  
Optical Magnification ◽  
Chromatic Aberrations ◽  
High Degree

Electron microscope design, and particularly the design of the imaging system, has reached a high degree of perfection. Present objective lenses perform up to their theoretical limit, while the whole imaging system, consisting of three or four lenses, provides very wide ranges of magnification and diffraction camera length with virtually no distortion of the image. Evolution of the electron microscope in to a routine research tool in which objects of steadily increasing thickness are investigated, has made it necessary for the designer to pay special attention to the chromatic aberrations of the magnification system (as distinct from the chromatic aberration of the objective lens). These chromatic aberrations cause edge un-sharpness of the image due to electrons which have suffered energy losses in the object.There exist two kinds of chromatic aberration of the magnification system; the chromatic change of magnification, characterized by the coefficient Cm, and the chromatic change of rotation given by Cp.

Cytoplasmic Organization in the Receptor Cells of the Crista Ampullaris

1972 ◽  
Vol 30 ◽  
pp. 60-61 ◽  
Author(s):  
Robert F. Dunn
Keyword(s):  
Fine Particles ◽  
Apical Cell ◽  
Apical Region ◽  
Receptor Cells ◽  
Cuticular Plate ◽  
Morphological Organization ◽  
Crista Ampullaris ◽  
Cytoplasmic Organization ◽  
High Degree ◽  
General Appearance

Receptor cells of the cristae in the vestibular labyrinth of the bullfrog, Rana catesbiana, show a high degree of morphological organization. Four specialized regions may be distinguished: the apical region, the supranuclear region, the paranuclear region, and the basilar region.The apical region includes a single kinocilium, approximately 40 stereocilia, and many small microvilli all projecting from the apical cell surface into the lumen of the ampulla. A cuticular plate, located at the base of the stereocilia, contains filamentous attachments of the stereocilia, and has the general appearance of a homogeneous aggregation of fine particles (Fig. 1). An accumulation of mitochondria is located within the cytoplasm basal to the cuticular plate.

Computer Reconstruction of the Cellular Architecture of the Daphnia Magna Optic Ganglion

1975 ◽  
Vol 33 ◽  
pp. 284-285
Author(s):  
E. R. Macagno ◽  
C. Levinthal
Keyword(s):  
Daphnia Magna ◽  
Genetic Background ◽  
Compound Eye ◽  
Synaptic Connectivity ◽  
Serial Sections ◽  
Cross Sectional ◽  
Small Crustacean ◽  
Optic Ganglion ◽  
Structural Invariance ◽  
High Degree

The optic ganglion of Daphnia Magna, a small crustacean that reproduces parthenogenetically contains about three hundred neurons: 110 neurons in the Lamina or anterior region and about 190 neurons in the Medulla or posterior region. The ganglion lies in the midplane of the organism and shows a high degree of left-right symmetry in its structures. The Lamina neurons form the first projection of the visual output from 176 retinula cells in the compound eye. In order to answer questions about structural invariance under constant genetic background, we have begun to reconstruct in detail the morphology and synaptic connectivity of various neurons in this ganglion from electron micrographs of serial sections (1). The ganglion is sectioned in a dorso-ventra1 direction so as to minimize the cross-sectional area photographed in each section. This area is about 60 μm x 120 μm, and hence most of the ganglion fit in a single 70 mm micrograph at the lowest magnification (685x) available on our Zeiss EM9-S.

Feasibility of Molecular Structure Determination With a High Resolution Electron Microscope

1968 ◽  
Vol 26 ◽  
pp. 338-339
Author(s):  
T. A. Welton
Keyword(s):  
Electron Microscope ◽  
Substrate Surface ◽  
Helical Axis ◽  
Base Plane ◽  
Resolution Electron ◽  
High Resolution Electron Microscope ◽  
High Degree ◽  
Degree Of Order ◽  
Purine Pyrimidine

An ultimate design goal for an improved electron microscope, aimed at biological applications, is the determination of the structure of complex bio-molecules. As a prototype of this class of problems, we propose to examine the possibility of reading DNA sequence by an imaginable instrument design. This problem ideally combines absolute importance and relative simplicity, in as much as the problem of enzyme structure seems to be a much more difficult one.The proposed technique involves the deposition on a thin graphite lamina of intact double helical DNA rods. If the structure can be maintained under vacuum conditions, we can then make use of the high degree of order to greatly reduce the work involved in discriminating between the four possible purine-pyrimidine arrangements in each base plane. The phosphorus atoms of the back bone form in projection (the helical axis being necessarily parallel to the substrate surface) two intertwined sinusoids. If these phosphorus atoms have been located up to a certain point on the molecule, we have available excellent information on the orientation of the base plane at that point, and can then locate in projection the key atoms for discrimination of the four alternatives.

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