scholarly journals Ethical problems of mitochondrial replacement

Author(s):  
Е.В. Введенская

Применение любой новой вспомогательной репродуктивной технологии, связанной с манипуляциями человеческими половыми клетками и эмбрионами неизбежно будет спорным с этической точки зрения. Такой технологией является митохондриальное замещение, которое позволяет родить здорового ребенка женщине, страдающей митохондриальным заболеванием. The use of any new assisted reproductive technology related to the manipulation of human sex cells and embryos will inevitably be controversial from an ethical point of view. This technology is mitochondrial replacement, which allows a woman suffering from mitochondrial dysfunction to give birth to a healthy child.

The article researches ethical problems of realization of human calling. On the basis of ideas of the ethics of E. Levinas and their interpretations the author proves the importance of ethical dimension of evaluation of calling as a way of self-actualization of a personality. The purpose of the study is to determine of the conditions and requirements for understanding of calling by personality. However, from the ethical point of view those conditions and requirements appeared to be independent from the individual aims and visions of calling. Therefore, reveals itself the transcendence of the purpose of calling, devotion of a person to over-personal aims and values. The research analyzes the interrelations between the ideas of calling and mission or assignments of a man in the world. The ethical problem presents also the realization of the ethical obligations versus desires and will of calling. The article researches the problem of the purpose of life related to individual understanding of calling. The other issue of the study is the topic of a highest good as the aim and ethical dimension for calling. The theme of destiny and predestination researched as relevant for the experience of calling as well as the phenomenon of gift. Calling is a realization of given to a person and of his or her gifts. For the conclusion was determined the multidimensional character of values of human calling. In the essence of this phenomenon revealed the combination of personal and transcendent, over-personal motives. There is a hierarchy of levels of good in the experience of calling. The person must be able to build up and understand those levels by means of ethical thinking in order to realize calling in the life. There could not be an irresponsible calling of a person. It has to be a correlation of calling with responsibility to family, society and the world of higher ethical values.


Author(s):  
Weihua GUO

LANGUAGE NOTE | Document text in Chinese; abstract also in English.儒家倫理從“天道”的角度賦予人之生命以神聖性和超越性,而輔助生殖技術則通過技術使人之“生命”從神聖性、超越性的形上境遇被拋入到世俗境遇中,生命的“袪魅”成為這一趨勢的集中表現。並由此,引發了“生命”的形上界定和由技術展現世俗化的生命界定之間的矛盾和衝突。儒家倫理為技術干預下的“生命”進行道德辯護的關鍵在於:儒家倫理應以一種辯證、開放的態度為輔助生殖技術展現的世俗化的生命倫理提供形而上學的精神本源基礎。By profoundly intervening in human life, human assisted reproductive technology is challenging the convictions of all well-established ethics, Confucian ethics included. Through such technology, human life is thrown from the divine, transcendent metaphysical situation it has traditionally held into this-worldly circumstances. In particular, human assisted reproductive technology brings with it a series of ethical problems. First, the sanctity of life is put in jeopardy. From this perspective, every human life is unique and independent. However, human assisted reproductive technology has the potential to destroy such uniqueness and independence. Second, human subjectivity is lost. An essential attribute of human life is that humans exist as active subjects to be respected, rather than as passive objects to be manipulated. When human assisted reproductive technology is used to control human life, human subjectivity is thrown into crisis. Finally, the existence of human life is fragmented. Human beings are “group” animals, and they live in families built on the basis of blood and marriage. This basis is usually taken as the origin or foundation of Confucian ethics. However, human assisted reproductive technology (especially AIH and reproductive cloning technology) has broken the traditional family structure. It has caused a crisis in the notion of family as an ethical entity and life becomes nothing but “debris.”In the face of such moral crises, it is time to explore Confucian ethics to help people out of their plight. Traditionally, Confucian ethics has a profound and rich content. It takes human life as valuable, sacred, transcendent and eternal. From the Confucian perspective, human life means not only existence as a natural object, but also existence of value and significance in the universe. In developing a proper Confucian ethics to direct the application of human assisted reproductive technology and guide its technical intervention in human life, this essay argues that we must recognize the following crucial point: a dialectical exploration and an open attitude are needed to enable Confucian ethics to provide the Confucian spirit of metaphysical origins and concerns to a new bioethics of assisted reproductive technology. That is, on the one hand, a bridge must be built to connect the metaphysical condition of real life in Confucian ethics with the technical interference of human assisted reproductive technology. On the other hand, it must be noted that human assisted reproductive technology reveals that the problem domain is not merely a simple technology ethics, but also involves deep philosophical or ethical change. Such exploration provides formal support for considering the ethical problems of human assisted reproductive technology from a comic philosophical view that the Confucian bioethical discourse of life must undertake.DOWNLOAD HISTORY | This article has been downloaded 60 times in Digital Commons before migrating into this platform.


2021 ◽  
Vol 66 (Special Issue) ◽  
pp. 40-40
Author(s):  
Emma Capulli ◽  
◽  
Elvira Passaro ◽  
◽  

"The procuring of eggs and compensatory measures for donors today present unresolved ethical and conceptual issues, which fuel the growth of the assisted reproductive technology (ART) industry. The speech proposes a problematization of the phenomenon from a legal point of view, supported by a rhetorical-argumentative analysis of the legal institutions. The legal provision of oocytes admits the only donation. It was deduced by analogy from the legislative provisions of available of organs and tissues (law no. 458 of 1967; law no. 301 of 1993; law no. 91 of 1999; law no. 483 of 1999), which provides for the balance between impairment of the psycho-physical sphere and goods that benefit from it. Is this balance comparable to the available of oocytes? Or does it need an autonomous redefinition? The various national regulations show that in Europe the term donation includes not only solutions of substantial gratuity, but also various forms of compensation. On one side this shows the fragility of the definition of donation, rhetorically constructed through the Aristotelian argument of the dissociation between reimbursement and remuneration, and on the other it makes clear the need to use logical-argumentative tools to disclose the criterion of hierarchization of values in game. It remains to be understood how ethical reflection, led by an argumentative legal analysis, can provide the tools to improve the functioning of a system that seems to render donors’ rights unfit for use. "


2015 ◽  
Vol 68 (9-10) ◽  
pp. 353-357 ◽  
Author(s):  
Artur Bjelica ◽  
Svetlana Nikolic

History of marital infertility is as long as the history of human civilization. Becoming aware about the importance of procreation, as well as the problems with which people may confront, has been the subject of interest since the moment of the first human community creation. Historically, each stage of social development, hence the development of science, has carried within itself certain findings more or less acceptable from today?s point of view. The development of human awareness and acquisition of findings based on empirical evidence have contributed to understanding and solution of the problem which was considered to be a result of force majeure until that moment and therefore could not be influenced. This paper deals with the previously mentioned issues through the review of historical development of assisted reproductive technology and its importance. The authors? intention was to present the developmental road of assisted reproductive technology through history succinctly with a special emphasis on the moments which have been of the crucial importance and which have marked certain stages of its development.


2016 ◽  
pp. 73-76
Author(s):  
B.M. Ventskivskiy ◽  
◽  
I.V. Poladych ◽  
S.O. Avramenko ◽  
◽  
...  

In recent years there has been an increase in the frequency of multiple pregnancies and the associated perinatal losses. It is a result of multiple pregnancy in ART refers to a high-risk gestation, at which premature births occur in 2 times more often than in singleton pregnancies. The objective: to determine the role of pro-inflammatory cytokines in the pathogenesis of premature labor in multiple pregnancy, as a result of assisted reproductive technology. Patients and methods. to determine the pro-inflammatory cytokines that all pregnant with bagtopliddyam held immunosorbent assay, defined concentrations of interleukin (IL) in serum and cervical mucus. Results. The analysis of the levels of pro-inflammatory cytokines (IL-1, IL-8) in the test environment, found high concentrations in the surveyed women with multiple pregnancy, due to the use of ART, compared with spontaneous multiple and singleton pregnancy. Increased concentration of proinflammatory cytokines in patients with multiple pregnancy by ART is associated with their synthesis at the system level, it stimulated foci of inflammation in the female genitals and extragenital localization. This correlates with the clinical data and statistical analysis, patients with multiple pregnancy as a result of ART had weighed infectious-inflammatory history. Conclusion. The study showed that elevated levels of proinflammatory cytokines in the systemic and local level in patients with multiple pregnancy due to ART, typical for women with miscarriage, because of the physiological course of pregnancy characterized by the predominance of anti-inflammatory cytokines that prevent rejection of the fetus as a foreign factor. Based on the data obtained proved the role of systemic inflammatory factors in the genesis of preterm labor in women with a multiple pregnancy, as a result of assisted reproductive technology. Key words: multiple pregnancy, assisted reproductive technology, premature birth, interleukine-1, interleukine-8.


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