3D Printing of a Novel Humic Acid and Polyquaternium-10 Polyelectrolyte Complex for Oral Controlled Drug Release Application

2016 ◽  
Author(s):  
Margaret Siyawamwaya
Keyword(s):  
Humic Acid ◽  
3D Printing ◽  
Drug Release ◽  
Polyelectrolyte Complex ◽  
Controlled Drug Release

A humic acid-polyquaternium-10 stoichiometric self-assembled fibrilla polyelectrolyte complex: Effect of pH on synthesis, characterization, and drug release

2016 ◽  
Vol 65 (11) ◽  
pp. 550-560 ◽  
Author(s):  
Margaret Siyawamwaya ◽  
Yahya E. Choonara ◽  
Pradeep Kumar ◽  
Pierre P. D. Kondiah ◽  
Lisa C. du Toit ◽  
...  
Keyword(s):  
Humic Acid ◽  
Drug Release ◽  
Polyelectrolyte Complex ◽  
Effect Of Ph ◽  
Complex Effect ◽  
Self Assembled

Synthesis of thermo-sensitive polyelectrolyte complex nanoparticles from CS-g-PNIPAM and SA-g-PNIPAM for controlled drug release

2014 ◽  
Vol 22 (9) ◽  
pp. 1004-1011 ◽  
Author(s):  
Minyi Qi ◽  
Guiying Li ◽  
Nana Yu ◽  
Yanfeng Meng ◽  
Xunyong Liu
Keyword(s):  
Drug Release ◽  
Polyelectrolyte Complex ◽  
Controlled Drug Release

scholarly journals A Study Based on Controlled Drug Release by 3D Printed Aloe-Vera Bi-Layer Tablet

2021 ◽  
pp. 522-531
Author(s):  
Anurag Verma ◽  
Piyush Mittal ◽  
Milind S. Pande ◽  
Neelanchal Trivedi
Keyword(s):  
3D Printing ◽  
Drug Release ◽  
Integral Functional ◽  
Aloe Vera ◽  
Controlled Drug Release ◽  
Immediate Release ◽  
Aloe Barbadensis ◽  
3D Printed ◽  
Medicinal Properties ◽  
Printing Techniques

Aloe-Vera or Aloe barbadensis (botanical name) is a plant with many medicinal properties and have great importance in Ayurveda. Its leaves are succulent, erect, forming a thick rosette. The internal translucent pulp of Aloe-Vera is bound to a waxy crust or cuticle, and its vascular tissues transport minerals as well as water from the soil. Aloe Vera is being used as a major skin rejuvenating product, although it has varied medicinal properties also. In the present study, an attempt to make a method to create bi-layer tablets of Aloe-Vera, utilizing 3D printing techniques is presented. The method created doesnt affect the integral functional characteristics of the tablet. The method here contains creating an immediate release and sustained release tablet for making the Aloe-Vera to be used directly by the person for its numerous health effects. The tablet is designed so to be consumed by vegans as well since it is completely herbal.

Surface charge-reversible polyelectrolyte complex nanoparticles for hepatoma-targeting delivery of doxorubicin

2015 ◽  
Vol 3 (30) ◽  
pp. 6185-6193 ◽  
Author(s):  
Xubo Zhao ◽  
Peng Liu ◽  
Qilei Song ◽  
Nan Gong ◽  
Liangwei Yang ◽  
...  
Keyword(s):  
Drug Release ◽  
Surface Charge ◽  
Polyelectrolyte Complex ◽  
Polymeric Nanoparticles ◽  
Controlled Drug Release ◽  
Targeting Delivery

Polymeric nanoparticles are greatly advancing the field of nanomedicine due to their ability for targeted and controlled drug release.

scholarly journals 3D printing of bioinspired compartmentalized capsular structure for controlled drug release

2021 ◽  
Vol 22 (12) ◽  
pp. 1022-1033
Author(s):  
Jingwen Li ◽  
Mingxin Wu ◽  
Wenhui Chen ◽  
Haiyang Liu ◽  
Di Tan ◽  
...  
Keyword(s):  
3D Printing ◽  
Drug Release ◽  
Controlled Drug Release

scholarly journals 3D Printing of Thermoresponsive Hydrogel Laden with an Antimicrobial Agent towards Wound Healing Applications

2021 ◽  
Vol 8 (6) ◽  
pp. 79
Author(s):  
Martyna Nizioł ◽  
Justyna Paleczny ◽  
Adam Junka ◽  
Amin Shavandi ◽  
Anna Dawiec-Liśniewska ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
3D Printing ◽  
Drug Release ◽  
Antimicrobial Agent ◽  
External Solution ◽  
Controlled Drug Release ◽  
Wound Dressings ◽  
Hydrogel Scaffolds ◽  
Thermoresponsive Hydrogel ◽  
Octenidine Dihydrochloride

Thermoresponsive hydrogel-based wound dressings with an incorporated antimicrobial agent can be fabricated employing 3D printing technology. A novel printable ink containing poly(N-isopropylacrylamide) (PNIPAAm) precursors, sodium alginate (ALG), methylcellulose (MC) that is laden with a mixture of octenidine dihydrochloride and 2-phenoxyethanol (Octenisept®, OCT) possess accurate printability and shape fidelity. This study also provides the protocol of ink’s use for the 3D printing of hydrogel scaffolds. The hydrogel’s physicochemical properties and drug release profiles from the hydrogel specimens to the external solution have been determined at two temperatures (20 and 37 °C). The release test showed a sustained OCT delivery into ultrapure water and the PBS solution. The temperature-responsive hydrogel exhibited antimicrobial activity against Staphylococcus aureus, Candida albicans, and Pseudomonas aeruginosa and demonstrated non-cytotoxicity towards fibroblasts. The thermoresponsive behavior along with biocompatibility, antimicrobial activity, and controlled drug release make this hydrogel a promising class of materials for wound dressing applications.

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