scholarly journals Unique Characteristics of Microsporum canis versus Trichophyton rubrum superficial skin infection.

Author(s):  
SUMANAS Bunyaratavej
2021 ◽  
Vol 4 (2) ◽  
Author(s):  
May Iyasya Sarumpaet ◽  
Dian Dwi Wahyuni

Dermatophytosis is a superficial skin infection caused by dermatophytes that infected keratinous skin tissue, dermatophytes form molecules that bind to keratin as a source of nutrients in the formation of colonization. Dermatophytes that cause dermatophytosis are Tricophyton sp, Epidermophyton sp and Microsporum sp. To find out the Profile of dermatophytes in patients with dermatophytosis in the Polyclinic of Dermatology and Venerology Dr. Ferdinand Lumbantobing Sibolga in 2019 conducted observational research with cross sectional design. The sample of this study were 75 patients who were new patients and had not used antifungal drugs. This sample is then examined by examination of KOH and cultured and then identified by Scotch-tape Preparation in a microscope. The prevalence of dermatophytosis in this study was 23% of skin cases. The majority of dermatophytosis patients are women (52%), the most age group is 46-65 years (30.7%) and is most often found in housewives (24%). The dermatophytes species found were Trichophyton rubrum, Trichophyton mentagrophytes and Microsporum canis with the most species Trichophyton rubrum (37.3%), which was then followed by Trichophyton mentagrophytes (16%). Tinea corporis, tinea cruris, tinea capitis, tinea pedis and tinea unguinum are dermatophytosis cases that were found in this study. It can be concluded that Trichophyton rubrum is the most common cause of dermatophytosis in Dr. Ferdinand Lumbantobing Sibolga with Tinea corporis is the most classified classification of dermatophytosis.


2020 ◽  
Vol 1 (1) ◽  
pp. 31-40
Author(s):  
Desi Harnis ◽  
Rusmawardiana ◽  
, Fifa Argentina

Background Superficial mycoses is a fungal infection of the skin, nails and hair thatcaused by dematophytes, yeast and mold. Superficial mycoses infections are commonlyfound in high temperature and humidity area such as Indonesia. Palembang is one ofregions in Indonesia has a high temperature and humidity, considered the incidenceof this disease is high. A retrospective study of new cases of superficial mycoses, datataken from medical records and register book at Policlinic of Dermatology andVenereology Dr. Moh. Hoesin Palembang during 5 years from January 2014-December2018. There were 1,236 (17.1%) new cases of superficial mycoses. Incidence ofsuperficial mycoses varies with range 6.9%-23%. The most common superficialmycoses is dermatophytes (38,3%). Microsporum canis, Trichophyton rubrum danTricophyton hmentagrophytes are frequent isolates in this study. The most age groupis 36-45 years (17.6%) with male more than female. Superficial mycoses are often foundin students (26.9%), followed by unskilled workers (20.8%). Of the 1,236 new cases,125 patients had comorbidities, such as malignancy 21 (16.8%) patients,cerebrovascular disease and diabetes mellitus each 16 patients (7.4%). Inguinal andabdomen are the most commonly infected regions. 656 (53.1%) patients was giventopical antifungal. The most common topical antifungal was ketoconazole 2% cream(62%) and systemic antifungal was itraconazole (55,3%).Conclusion: Cases ofsuperficial mycoses, especially dermatophytosis and Malassezia were still commonlyfound, especially in Palembang.


2019 ◽  
Vol 27 (1) ◽  
Author(s):  
Serapio Romero Gavilán

Trabajo de investigación desarrollado con el objetivo de conocer la frecuencia de la dermatofitosis humana en una comunidad con desigualdad social. Hipótesis: la dermatofitosis humana es una afección fúngica muy frecuente en comunidades con desigualdad social. Zona de estudio: comunidad con desigualdad social periurbana de la ciudad de Ayacucho. Tipo de estudio: no experimental. Diseño de estudio: descriptivo-transversal. Muestra: no probabilística, individuos con signos de afecciones compatibles a micosis superficial. Metodología: muestras de escamas de piel, pelos, fragmentos de uñas de pies y manos, escamas de planta, espacios interdigitales y otras partes de cuerpo, fueron tomadas con una hoja de bisturí de filo romo o con el borde de un portaobjetos previa desinfección con alcohol al 70% y colocadas en sobres de papel oscuro etiquetados, en el laboratorio de Epidemiología y Micología de la Universidad Nacional de San Cristóbal de Huamanga, se realizó la observación directa con KOH al 20% y la siembra en placas Petri conteniendo Agar Sabouraud y Agar selectivo para hongos patógenos, después de una incubación a 25ºC por hasta 14 días; las colonias coincidentes con dermatofitos fueron observados al microscopio para identificarlos. Resultados: se ha encontrado que 85/153 (55,5%) presentaron diversas formas de dermatofitosis, no se observó preferencia de la dermatofitosis humana con relación al género (p> 0,05), los factores asociados a la dermatofitosis determinados estadísticamente (p< 0,05) fueron la higiene, el piso de la vivienda y la crianza de animales, se han identificado las especies de Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum canis y Microsporum gypseum.


Mycoses ◽  
2020 ◽  
Vol 63 (7) ◽  
pp. 683-693
Author(s):  
Hailin Zheng ◽  
Oliver Blechert ◽  
Huan Mei ◽  
Liyu Ge ◽  
Jia Liu ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Yunus Oc ◽  
Bekir Eray Kilinc ◽  
Sahin Cennet ◽  
Mehmet Metin Boyacioglu ◽  
Rodi Ertugrul ◽  
...  

Background. Osteoid osteoma (OO) is one of the most commonly occurring benign bone tumors. It constitutes 10-12% of benign bone tumors and 2-3% of primary bone tumors. In radiofrequency ablation (RFA) treatment, the cells of the tumor are thermally inactivated by the help of electrodes shaped like needles. In our study, we aimed to show the major and minor complications in patients undergoing RFA and to show what should be done to prevent these complications. Methods. The study was carried out as a prospective study on the follow-up of 87 osteoid osteoma patients treated between 2015 and 2017. The youngest of the patients was 1 year old and the oldest was 42 years old. The RFA procedure lasted 10 min on average, excluding anesthesia and preparation. All lesions were ablated at 90 degrees for 7 minutes with the heat increased gradually. All patients were followed up for 1 day in the orthopedics clinic. Results. Complications were observed in 7 patients. The lesions with the most complications were observed to be in the tibia, second-degree burns were seen in 2 patients, and superficial skin infection was observed in 2 patients. In 1 patient, the probe tip was broken and remained within the bone. Intramuscular hematoma was detected in 1 lesion located in the proximal femur. A complaint of numbness in the fingers developed in a lesion located in the metacarpus. Conclusion. Preventive measures should be taken before the procedure in order to prevent minor complications, and, for major complications, close follow-up should be done after the procedure and patients should be kept away from heavy physical activities for the first 3 months.


2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Rui-Na Zhang ◽  
Jun-Ying Zhao ◽  
Lin-Feng Li

Trichophyton rubrum is one of the most common types of dermatophyte, causing superficial skin mycosis in human populations. Although laser treatment of onychomycosis has been proven to be effective in the clinic, the underlying mechanism of the effect of the laser on fungal growth is not clear. The objective of the present study was to observe the ultrastructural changes of Trichophyton rubrum following laser irradiation and compare the transcriptome differences between the laser irradiation group and control group. In the present study, scanning electron microscopy and transmission electron microscopy were used to observe the ultrastructural changes following the laser irradiation of Trichophyton rubrum. We also performed RNA-seq to investigate the effects of laser irradiation on Trichophyton rubrum by comparing the transcriptome pattern with the control. Morphological observation with electron microscopy indicated that laser irradiation resulted in the destruction of the cell membrane system. A significant induction of apoptosis was noted compared with the control group, which was confirmed by the formation of the myeloid body and protein aggregates in the cytoplasm. RNA-seq demonstrated that the expression levels of Acyl-CoA N-acyltransferase and S-adenosyl-L-methionine-dependent methyltransferase were increased in the laser irradiation group. This result indicated that laser irradiation triggered the initiation of the damage repair pathway. In conclusion, the present study suggested that laser irradiation caused physiological injury and therefore inhibited the growth of Trichophyton rubrum.


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