scholarly journals Efficacy of topical 5% fluorouracil (5%- FU) needling in vitiligo: فعالية الحقن الموضعي بالإبر الدقيقة لـ fluorouracil  5% في علاج البهاق

2021 ◽  
Vol 5 (4) ◽  
pp. 34-28
Author(s):  
Mai Abdulkhaliq Ibrahiem, Mohammed Adel Ismaiel Mai Abdulkhaliq Ibrahiem, Mohammed Adel Ismaiel
Keyword(s):  
Side Effects ◽  
Prospective Study ◽  
The Body ◽  
University Hospital ◽  
Safe Method ◽  
Study Results ◽  
One Year ◽  
A Prospective Study ◽  
Treatment Improvement

Objective: The aim of this study is to assess the efficacy of topical 5- fluorouracil (5%- FU) with micro needling in treating stable vitiligo. In addition to, assessment the side effects of the treatment. Patients and Methods: A Prospective study (Before& After) conducted for the period one year (April 2019- April2020)at Tishreen University Hospital in Lattakia- Syria, 31 patients with stable vitiligo who received treatment with micro needling and topical 5- fluorouracil (5%- FU) were included in this study. Results : The median age was 36 years, 67.70% of patients were female. Focal type was found in 61.3%, and most common sites of vitiligo involvement were hand and feet (33.7%), followed by trunk (24.8%)and extremities (24.8%). After 6 months of treatment, improvement was excellent in 63.4%, and very good in 23.8%. The lesions of neck and trunk were responded better to treatment than those in other parts of the body. Regarding of side effects, pain, erythema, and itching were reported in 100% followed by ulceration in (16.1%). Conclusion: Topical 5%- fluorouracil (5%- FU) with needling appears to be an effective and safe method in treating stable vitiligo. Except of pain, erythema, and itching after procedure, significant complications not occurred in most patients.

TREATMENT OF TRIGGER FINGERS BY INJECTION OF METHYLPREDNISOLONE ACETATE AND LIDOCAINE (DEPO-MEDROL®)

Hand Surgery ◽  
1996 ◽  
Vol 01 (02) ◽  
pp. 103-105
Author(s):  
J. Joris Hage ◽  
Jaap D.K. Munting
Keyword(s):  
Side Effects ◽  
Prospective Study ◽  
Success Rate ◽  
Adult Patients ◽  
Methylprednisolone Acetate ◽  
Short Term ◽  
Local Injections ◽  
One Year ◽  
A Prospective Study

Thirty-six adult patients with 44 trigger fingers of less than four months' duration entered a prospective study on the efficiency of treatment with local injections of a combination of corticosteroids and lidocaine. From this study it may be concluded that the short-term success rate (93%) of one to three injections of methylprednisolone and lidocaine 2% (Depo-Medrol®) is comparable to that achieved by surgical or percutaneous tenolysis. At one year of follow-up, this success rate still amounted to 86%. In our hands, this therapy is without complications or side effects.

scholarly journals Ultrasound guided intralesional bleomycin therapy for cystic lymphangioma in childhood

2017 ◽  
Vol 4 (4) ◽  
pp. 1496
Author(s):  
Pradyumna Pan
Keyword(s):  
Aqueous Solution ◽  
Side Effects ◽  
Prospective Study ◽  
Complete Resolution ◽  
Poor Response ◽  
Cystic Lymphangioma ◽  
The Body ◽  
Intralesional Injection ◽  
Ultrasound Guided ◽  
A Prospective Study

Background: Lymphangiomas are benign hamartomatous lymphatic tumors, characterized by multiple communicating lymphatic channels and cystic spaces. They occur in nearly all regions of the body but are most frequently seen in the neck (75%), axilla (20%), and inguinal areas (2%). This study aims to evaluate the effectiveness of intralesional bleomycin sclerotherapy in the treatment of cystic lymphangioma in children and to determine the incidence of complications in the treatment.Methods: This is a prospective study of 36 children diagnosed with cystic lymphangioma and treated with intralesional injection of bleomycin aqueous solution from 2008 to 2015.Results: Complete resolution was seen in (16/36) of lesions, (17/36) had a good response and (3/36) had a poor response. The tumour recurred in 3 patients. No other serious complications or side effects were observed.Conclusions: Intralesional bleomycin therapy was very effective in the treatment of cystic lymphangioma. Our results were comparable to other published studies. Bleomycin administered as intralesional injection was found to be safe as there was no serious complication or side effect observed in this study. 

A Prospective Study on Analysis of Histopathological Variations in Post Cholecystectomy Specimens Done for Benign Conditions in a Tertiary Care Hospital, Tirupati

2021 ◽  
Vol 8 (32) ◽  
pp. 2956-2961
Author(s):  
Gandikota Venkata Prakash ◽  
Ajay Babu K ◽  
Madan Sundar ◽  
Purushotham G ◽  
Saddi Tejaswi ◽  
...  
Keyword(s):  
Gall Bladder ◽  
Prospective Study ◽  
General Surgery ◽  
Care Hospital ◽  
Biliary Disease ◽  
Age Group ◽  
Female Ratio ◽  
Study Results ◽  
One Year ◽  
A Prospective Study

BACKGROUND Cholecystectomy is a common surgical procedure done worldwide for both benign and neoplastic conditions. Cholecystectomy for benign conditions is performed based on clinical signs, symptoms, Ultrasound, CT. Hence there is fair chance of missing early malignant lesions like carcinoma-in-situ and other early carcinomas. Aim: The aim of the study is to analyse histopathological variations in post cholecystectomy specimens done for benign lesions. METHODS The study was conducted in Department of General Surgery, SVRRGGH, Tirupati, for a period of one year, from March 2019 to April 2020. This is a prospective Study conducted among 100 Patients, conducted over a period of one year from time of IEC approval from March 2019 to April 2020. All patients who underwent cholecystectomy for benign biliary disease and gall stone were included in the study. All patients with pre-diagnosed empyema gallbladder, gallbladder malignancy, gallbladder mass, and gallstones associated with obstructive jaundice are excluded from the study. RESULTS In our study, 100 cases of gall bladder disease were studied in the age group of 18 – 70 years, for a period of 1 year from March 2019 in the department of General surgery, SVRRGGH. Occurrence is high in patients of age group 18 – 45 years (65 %). The male to female ratio is 0.5:1 with female preponderance. The most common histopathologic finding was chronic calculus cholecystitis (59 %).Adenocarcinoma of gall bladder (2 %) of the cases with no preoperative suspicion of malignancy. CONCLUSIONS The occurrence of Incidental GBC found in my study is 2 %. Due to high estimate of residual disease, re-resection is still a curative option and is to be considered for pT2 & pT3, but not CBD removal. Prognosis usually is dismal, and five-year survival rates have been reported to be less than 5 % for more advanced stages. KEYWORDS Histopathology, Variations, Cholecystectomy, Specimen, Benign

The role of blood inflammatory markers in the diagnosis of appendicitis in children: a prospective study from a University Hospital in Greece

2020 ◽  
Vol 178 (11) ◽  
Author(s):  
George Sakellaris ◽  
Dimitra Dimopoulou ◽  
Maria Niniraki ◽  
Anastasia Dimopoulou ◽  
Athanasios Alegakis ◽  
...  
Keyword(s):  
Prospective Study ◽  
Inflammatory Markers ◽  
University Hospital ◽  
A Prospective Study

Customised gold weight eyelid implantation in paralytic lagophthalmos

2008 ◽  
Vol 122 (10) ◽  
pp. 1088-1091 ◽  
Author(s):  
N Jayashankar ◽  
K P Morwani ◽  
M J Shaan ◽  
S R Bhatia ◽  
K T Patil
Keyword(s):  
Visual Acuity ◽  
Prospective Study ◽  
Study Design ◽  
Study Group ◽  
Upper Eyelid ◽  
Eyelid Closure ◽  
Gold Weight ◽  
One Year ◽  
A Prospective Study

AbstractGold eyelid implantation is widely considered the procedure of choice to reanimate the upper eyelid in paralytic lagophthalmos. Commercially supplied implants are not readily available in all places and are sometimes cumbersome to import.Objective:We aimed to devise a method whereby every surgeon performing gold eyelid implantation could have easy and quick access to the implant. Furthermore, we aimed to develop a means of creating an implant of the exact weight required for complete eyelid closure.Study design and setting:A prospective study was performed from 1997 to 2005 in a tertiary research hospital, involving 50 subjects requiring gold upper eyelid implantation and using the technique in question.Results:Only patients with a minimum follow up of one year were included in the study group. Symptoms improved in 96 per cent of subjects, who were able to dispense with eyedrops and eye ointments. Visual acuity improved in 92 per cent of patients. There were two extrusions amongst the early cases.Conclusion and significance:Customised gold eyelid implantation offers an alternative in regions where commercial implants are not easily obtained.

scholarly journals Fungal rhinosinusitis: A prospective study in a University hospital of Uttar Pradesh

2013 ◽  
Vol 31 (3) ◽  
pp. 266 ◽  
Author(s):  
G Banerjee ◽  
P Gupta ◽  
M Singh ◽  
MM Goel ◽  
V Verma ◽  
...  
Keyword(s):  
Prospective Study ◽  
Uttar Pradesh ◽  
University Hospital ◽  
Fungal Rhinosinusitis ◽  
A Prospective Study
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