A Prospective Study on Analysis of Histopathological Variations in Post Cholecystectomy Specimens Done for Benign Conditions in a Tertiary Care Hospital, Tirupati

2021 ◽  
Vol 8 (32) ◽  
pp. 2956-2961
Author(s):  
Gandikota Venkata Prakash ◽  
Ajay Babu K ◽  
Madan Sundar ◽  
Purushotham G ◽  
Saddi Tejaswi ◽  
...  
Keyword(s):  
Gall Bladder ◽  
Prospective Study ◽  
General Surgery ◽  
Care Hospital ◽  
Biliary Disease ◽  
Age Group ◽  
Female Ratio ◽  
Study Results ◽  
One Year ◽  
A Prospective Study

BACKGROUND Cholecystectomy is a common surgical procedure done worldwide for both benign and neoplastic conditions. Cholecystectomy for benign conditions is performed based on clinical signs, symptoms, Ultrasound, CT. Hence there is fair chance of missing early malignant lesions like carcinoma-in-situ and other early carcinomas. Aim: The aim of the study is to analyse histopathological variations in post cholecystectomy specimens done for benign lesions. METHODS The study was conducted in Department of General Surgery, SVRRGGH, Tirupati, for a period of one year, from March 2019 to April 2020. This is a prospective Study conducted among 100 Patients, conducted over a period of one year from time of IEC approval from March 2019 to April 2020. All patients who underwent cholecystectomy for benign biliary disease and gall stone were included in the study. All patients with pre-diagnosed empyema gallbladder, gallbladder malignancy, gallbladder mass, and gallstones associated with obstructive jaundice are excluded from the study. RESULTS In our study, 100 cases of gall bladder disease were studied in the age group of 18 – 70 years, for a period of 1 year from March 2019 in the department of General surgery, SVRRGGH. Occurrence is high in patients of age group 18 – 45 years (65 %). The male to female ratio is 0.5:1 with female preponderance. The most common histopathologic finding was chronic calculus cholecystitis (59 %).Adenocarcinoma of gall bladder (2 %) of the cases with no preoperative suspicion of malignancy. CONCLUSIONS The occurrence of Incidental GBC found in my study is 2 %. Due to high estimate of residual disease, re-resection is still a curative option and is to be considered for pT2 & pT3, but not CBD removal. Prognosis usually is dismal, and five-year survival rates have been reported to be less than 5 % for more advanced stages. KEYWORDS Histopathology, Variations, Cholecystectomy, Specimen, Benign

scholarly journals Halitosis: Its Aetiology and Psychosocial Impact- A Hospital Based Study

2021 ◽  
Vol 29 (2) ◽  
pp. 145-150
Author(s):  
Gopika Kalsotra ◽  
Monica Manhas ◽  
Sachin Gupta ◽  
Heemani Bhardwaj ◽  
Parmod Kalsotra ◽  
...  
Keyword(s):  
Social Life ◽  
Laryngopharyngeal Reflux ◽  
Systemic Disease ◽  
Tertiary Care ◽  
Neck Surgery ◽  
Psychosocial Impact ◽  
Care Hospital ◽  
Female Ratio ◽  
Study Results ◽  
A Prospective Study

Introduction Halitosis means bad or unpleasant odour from oral cavity. It causes embarrassment to the patients and affects their social life and communication. This study aims to find the causes of halitosis and to assess its psychosocial impact. Materials and Methods A prospective study was conducted in the department of Otorhinolaryngology and Head Neck Surgery in a tertiary care hospital. It included 165 patients, presenting to the ENT OPD with chief complains of oral malodour for at least 3 months. The patients in the age above 15 years and below 75 years, irrespective of gender, were included in the study. Results The age of the patients ranged from 15 to 75 years with a mean age of 52.24 ± 15.67 with male: female ratio of 7:10. The most common cause of halitosis in the present study included chronic rhinosinusitis (38.7%), gingivitis/periodontitis (19.39%), tonsillitis (4.84%), laryngopharyngeal reflux (2%), deep neck space infections (1.2%). In 23.56%, the halitosis was a symptom of an underlying malignancy. Conclusion Halitosis from an extra oral origin can be the sign of an underlying systemic disease or malignancy. The consultation should be done with the periodontist, ENT specialist and a physician.

scholarly journals A prospective study of intestinal obstruction in paediatric age group

2017 ◽  
Vol 4 (6) ◽  
pp. 1979
Author(s):  
Amul Bhedi ◽  
Miten Prajapati ◽  
Arnab Sarkar
Keyword(s):  
Intestinal Obstruction ◽  
Prospective Study ◽  
Hypertrophic Pyloric Stenosis ◽  
Age Groups ◽  
Total Mortality ◽  
Infants And Children ◽  
Age Group ◽  
Female Ratio ◽  
Paediatric Age ◽  
A Prospective Study

Background: Intestinal obstruction can occur at any age in the paediatric population1-4. Bowel obstruction in children differs from that in adults in terms of etiology, presentation and even the management. The aim of the study was to find out various etiologies, clinical features, outcome and mortality of paediatric age groups with intestinal obstruction and their relation to age and sex distribution.Methods: This is a prospective study of 50 cases of paediatric age group with signs and symptoms of intestinal obstruction which were admitted in Sir Sayajirao Gaekwad Hospital, Vadodara, India during period of December 2004 to November 2006. Surgical intervention was carried out where indicated otherwise patients were managed conservatively. Data was analysed in SPSS version 10 statistical software for percentage and frequencies.Results: Total 50 patients were included in the study. Among these 30 were males and 20 were females with M: F ratio of 3:2. Majority of them were 25 neonates of age group of 1-7 days (50%), followed by 7 infants of 1 months- 1 years (14%) and 18 children aged 1 years-12 years (36%).  Out of 50 patients, 41 (82%) patients had congenital causes in which 21(42%) patients had imperforate anus followed by Hirschprung’s disease in 8(16%), Meckel’s diverticulum in 6(12%), jejunal atresia in 4(8%), hypertrophic pyloric stenosis in 2 patients (4%) and 9(18%) patients had acquired causes in which intussusception was in 5(10%) patients, abdominal tuberculosis in 2(4%) and gangrenous appendix in 2(4%) patients. Total mortality was 6 out of 25 neonates and there were no mortality in infants and children groups.Conclusions: Majority of patients were neonates than infants and children with slight male preponderance with male: female ratio of 3:2. Congenital causes of intestinal obstruction were more common (82%) than the acquired causes (18%). Postoperative septicaemia was more common and overall mortality was exclusively in neonates.

scholarly journals A PROSPECTIVE STUDY ON SEIZURES AMONG PEDIATRIC AGE GROUP IN TERTIARY CARE HOSPITAL

2020 ◽  
pp. 63-64
Author(s):  
Srenivas. A ◽  
Sathiya Suresh
Keyword(s):  
Tertiary Care ◽  
Age At Onset ◽  
Preterm Neonates ◽  
Care Hospital ◽  
Age Group ◽  
Neonatal Seizures ◽  
Female Ratio ◽  
Pediatric Age Group ◽  
Female Male Female ◽  
A Prospective Study

Seizures represent signal of neurological disease in the newborn period and these convulsive phenomena are the most frequent of the overt manifestation of neonatal neurological disorders.. The objective of this study was to study the incidence of pediatrics (0-12 years) seizures. To study the etiology and pattern of seizures. Methods: 200 Subjects who had seizures were included in the study. Relevant history was ascertained from a patient’s parents or a reliable relative or attendant, medical records and the referring physicians note, specifically from mother in case of neonatal seizures i.e. age at onset of seizures, seizure activity with special emphasis on occurrence of 1st seizures, duration of seizures, number and type of seizures, associated autonomic changes, medications required to control seizures, response time to medications, and possible causes for determination of etiology. A detailed antenatal, natal and postnatal history was taken. Results: Out of 200 study subjects 35.89% were in neonatal age group, of which 64.10% and 35.90% were male and female respectively and 64.11%. out of neonatal seizures, 64.10% neonates were male and 35.90% were female. Male: Female ratio was 1.79:1. The seizures were common in male neonates. Subtle seizures were the commonest type of seizures observed both in term and preterm neonates. Conclusions: The various types of seizure were compared with the preterm and term neonates and it was found statistically significant

scholarly journals THE SPECTRUM OF MALIGNANT SOLID PEDIATRIC TUMORS IN THE AGE GROUP OF 0-18 YEARS: A PROSPECTIVE STUDY

2020 ◽  
pp. 1-3
Author(s):  
Sandhya Bordia ◽  
Praveen Kumar Jain*
Keyword(s):  
Prospective Study ◽  
Pediatric Tumors ◽  
Age Group ◽  
Female Ratio ◽  
Spindle Cell Neoplasm ◽  
Medical College ◽  
Pediatric Age Group ◽  
Solid Malignancies ◽  
Male Female Ratio ◽  
A Prospective Study

OBJECTIVE: The purpose of this prospective study is to study the spectrum of pediatric solid malignancies at our institution. METHOD: This study is under taken to evaluate the incidence and morphological features of solid malignant paediatric tumors in eighteen years and below. The material for present study is obtained from FNAC in cytology and biopsy specimen in histology department of RNT Medical college, Udaipur. RESULT: A total number 60 cases of malignant solid pediatric tumors of age group 0-18 years were diagnosed in Department of Pathology RNT Medical college Udaipur, during a period of two years. The number of malignancies diagnosed by Cytology accounted for 53.33% while Histopathology contributed 46.67% respectively. The male: Female ratio of childhood solid malignancies was 1.73:1. In malignant solid pediatric tumors CNS tumors were the commonest constituting 30% followed by Lymphoma 23.33%, Bone tumors 11.67% and neuroblastoma, retinoblastoma & spindle cell neoplasm 3.33% each. CONCLUSION: Our study concluded that solid malignant pediatric tumors contribute also a health problem in Udaipur region affecting all pediatric age group but more prevalent in the age group 6-10 years & 15-18 years.

scholarly journals FAILURE OF THROMBOLYSIS WITH STREPTOKINASE IN ACUTE MYOCARDIAL INFARCTION USING ECG CRITERIA: AN OBSERVATIONAL STUDY

2020 ◽  
pp. 1-3
Author(s):  
Prabhat Kumar Sinha ◽  
Kumari Suruchi ◽  
Pradeep Kumar Sharma ◽  
Debarshi Jana
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Observational Study ◽  
Prospective Study ◽  
Diabetic Patients ◽  
Age Group ◽  
Medical College ◽  
One Year ◽  
A Prospective Study ◽  
Ecg Criteria

To Study failure of thrombolysis with streptokinase in acute myocardial infarction using E.C.G criteria a prospective study of patients presenting with acute myocardial infarction in Department of Medicine, Darbhanga Medical College and Hospital, Laheriasarai, Bihar for a period of one year from December 2018 to November 2019. A total of 220 patients who presented with acute myocardial infarction were included in the study. Out of 220 patients 193(87.7%) males and 27 (12.3%) females participated in the study. All the patients underwent thrombolysis with streptokinase. Out of 220 patients who were being thrombolysed with streptokinase, most of them (97; 41.1%) were in the age group of 56-65 years. Out of all the patients who underwent thrombolysis (n=220), thrombolytic failure was observed in 121 (55%) patients. Failure rate was significantly higher in the age group of 56-65 years (88; 72.7%). Significantly higher prevalence of thrombolytic failure with streptokinase was observed among diabetic patients (65.2% ) as compared to non diabetics (52.3%).

scholarly journals Analysis of enteric ileal perforation: a prospective study in a tertiary care hospital

2017 ◽  
Vol 4 (3) ◽  
pp. 899
Author(s):  
Prabu Shankar S. ◽  
Sudarshan P.B. ◽  
Sundaravadanan B.S.
Keyword(s):  
Prospective Study ◽  
Tertiary Care ◽  
Wound Dehiscence ◽  
Fecal Fistula ◽  
High Morbidity ◽  
Care Hospital ◽  
Female Ratio ◽  
Ileal Perforation ◽  
Delay In Diagnosis ◽  
A Prospective Study

Background: Intestinal perforation as a complication of enteric fever is still a serious problem in developing nations. Enteric ileal perforation is associated with high morbidity and mortality and many patients present in a severe toxic state because of delay in diagnosis and late presentation to hospital.Methods: A prospective study was conducted to assess the prognostic factors in enteric ileal perforation. Observations were made regarding symptoms, signs, duration of illness and presentation of patients to the hospital after acute episode. Per operative findings regarding site, size and number of perforations were recorded. Operative procedures were simple closure, ileostomy, or resection of diseased segment including right hemicolectomy done for associated caecal perforation and entero enteric anastomosis. Post-operative complications like wound infection, wound dehiscence, residual abscess, faecal fistula and deaths were documented.Results: There were 50 enteric ileal perforation cases with a age range of 13-80 with a mean age of 30.7. Male: female ratio was 11: 1. 85% of patients presented within 48 hrs of onset of symptoms of perforation and there is significant mortality in patients who presented more than 48 hrs of onset of symptoms of perforation (57.14%). Mortality was high in multiple perforation group (40%) and also higher incidences of fecal fistula and wound dehiscence.Conclusions: Age and sex have no bearing on the outcome. Perforation presentation interval, delay in surgery, number of perforations are important prognostic markers for typhoid ileal perforation. 

scholarly journals A prospective study of 20 cases of maternal outcome in morbidly adherent placenta in tertiary care hospital

2017 ◽  
Vol 6 (2) ◽  
pp. 571
Author(s):  
Krishna Vora ◽  
Pallavi Chandana ◽  
Amrita Patel ◽  
Mahima Jain
Keyword(s):  
Prospective Study ◽  
Maternal Outcome ◽  
Placenta Praevia ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Care Hospital ◽  
Morbidly Adherent Placenta ◽  
Adherent Placenta ◽  
One Year ◽  
A Prospective Study

Background: Morbidly adherent placenta with its variants is one of the most feared complication causing high morbidity and mortality in obstetrics. Aim of this study is to help in identifying high risk pregnancies, planning line of management of morbidly adherent placenta. The objective of the study wad to evaluate the risk factors, different modes of management, maternal outcome in case of morbidly adherent placenta.Methods: A prospective study for one year was done to describe the incidence, causes, treatment, complications, and maternal morbidity and mortality associated with morbidly adherent placenta.Results: A total of 20 cases of morbidly adherent placenta were studied over one-year span at our Institute. Most of the women with morbidly adherent placenta were in the age group of 26-30years (55%).The most common aetiology of morbidly adherent placenta was previous caesarean scar with placenta praevia (85%). In majority, placenta accreta found. Total abdominal hysterectomy done in 12 patient and subtotal hysterectomy in 6 cases. Trial haemostasis with uterine sparing in 2 cases out of which one case underwent total hysterectomy due to massive haemorrhage on same day. Associated Bladder repair in adherent placenta with invasion of bladder was needed in 10% cases. There was 1 maternal death noted in this study.Conclusions: Leading cause of morbidly adherent placenta is previous caesarean section with placenta praevia, high index of suspicion, early antenatal diagnosis, planned surgery at high care centre with multi-disciplinary expertise, anticipation of blood volume transfusion, Delivery of foetus without manipulating placenta are key steps to reduce morbidity and mortality in morbidly adherent placenta. The decision to perform hysterectomy and conservative management to be individualized. Timely decision is the key to get success in morbidly adherent placenta as in other obstetric emergencies.

scholarly journals A study of hypertensive disorders of pregnancy and the fetal outcome in a tertiary care hospital: a prospective study

2020 ◽  
Vol 9 (8) ◽  
pp. 3275
Author(s):  
Sangamesh S. Mathapati ◽  
Aruna M. Biradar ◽  
Laxmi S. Sangolli ◽  
Nidhi A. Mangalwadi ◽  
Gamini B. S. ◽  
...  
Keyword(s):  
Prospective Study ◽  
Laboratory Evaluation ◽  
Research Centre ◽  
Hypertensive Disorder ◽  
Care Hospital ◽  
Age Group ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders ◽  
A Prospective Study ◽  
In Pregnancy

Background: Pregnancy induced hypertension is one of the major causes of feto maternal morbidity and mortality in pregnancy. The exact cause of PIH is unknown certain factors are known to increase the risk of PIH such as risk factor includes that young women with first pregnancy.Methods: The objective of this study was to assess the socio-demographic and clinico-pathological profile of the patients with hypertensive disorders of pregnancy and its associated fetal outcomes. A prospective study was conducted in department of obstetrics and gynecology Shri B. M. Patil Medical College, Hospital and Research Centre, BLDE (Deemed to be University), Vijayapura Karnataka from 15th July to 15th December 2018. All women admitted to labour ward with diagnosis of hypertensive disorders of pregnancy were included in the study after ruling out the exclusion criteria and thorough history, examination and laboratory evaluation were done and followed till delivery.Results: A total of 123 pregnant women with hypertensive disorder of pregnancy were enrolled in the study. Most of the participants were in the age group of 20 to 30 years. The PIH was seen mostly in primigravida, lower socioeconomic status and with lower educational levels. Emergency LSCS is the most common mode of delivery.Conclusions: The hypertensive disorder in pregnancy affects the majorly younger age group. It is most commonly seen in low socio-economic and uneducated population. Hence, there should be provided with proper antenatal care, early detection of hypertensive disorders for better feto-maternal outcome.

scholarly journals Efficacy of topical 5% fluorouracil (5%- FU) needling in vitiligo: فعالية الحقن الموضعي بالإبر الدقيقة لـ fluorouracil  5% في علاج البهاق

2021 ◽  
Vol 5 (4) ◽  
pp. 34-28
Author(s):  
Mai Abdulkhaliq Ibrahiem, Mohammed Adel Ismaiel Mai Abdulkhaliq Ibrahiem, Mohammed Adel Ismaiel
Keyword(s):  
Side Effects ◽  
Prospective Study ◽  
The Body ◽  
University Hospital ◽  
Safe Method ◽  
Study Results ◽  
One Year ◽  
A Prospective Study ◽  
Treatment Improvement

Objective: The aim of this study is to assess the efficacy of topical 5- fluorouracil (5%- FU) with micro needling in treating stable vitiligo. In addition to, assessment the side effects of the treatment. Patients and Methods: A Prospective study (Before& After) conducted for the period one year (April 2019- April2020)at Tishreen University Hospital in Lattakia- Syria, 31 patients with stable vitiligo who received treatment with micro needling and topical 5- fluorouracil (5%- FU) were included in this study. Results : The median age was 36 years, 67.70% of patients were female. Focal type was found in 61.3%, and most common sites of vitiligo involvement were hand and feet (33.7%), followed by trunk (24.8%)and extremities (24.8%). After 6 months of treatment, improvement was excellent in 63.4%, and very good in 23.8%. The lesions of neck and trunk were responded better to treatment than those in other parts of the body. Regarding of side effects, pain, erythema, and itching were reported in 100% followed by ulceration in (16.1%). Conclusion: Topical 5%- fluorouracil (5%- FU) with needling appears to be an effective and safe method in treating stable vitiligo. Except of pain, erythema, and itching after procedure, significant complications not occurred in most patients.

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