scholarly journals HUBUNGAN PEMANFAATAN TUMBUHAN PASAK BUMI (Eurycoma longifolia Jack.) SEBAGAI OBAT TRADISIONAL DAN BIOAKTIVITASNYA

2019 ◽  
Vol 10 (2) ◽  
pp. 109
Author(s):  
Marina Silalahi
Keyword(s):  
Erectile Dysfunction ◽  
Traditional Medicine ◽  
Production Quality ◽  
Activity Increase ◽  
Cultivation Method ◽  
Eurycoma Longifolia ◽  
Review Articles ◽  
On Line ◽  
Eurycoma Longifolia Jack ◽  
The Relationship

Pasak bumi (Eurycoma longifolia Jack.) is a species belonging Simarobuaceae has been long used as traditional medicine, which known very well as aphrosidiac. The studies have been conducted to reveal the benefits of E. longifolia through ethnobotany, phytochemical, and bioessay approaches, but the review articles on the its utilization and bioactivity limited. This article is based on scientific articles published on line or off-line, then synthesized so that to be information the relationship between use and bioactivity. Ethnobotany of E. longifolia have been used as a medicine for fever, malaria, improve stamina, antimalarial, antidiabetic, anticancer, aphrodisiac, overcoming erectile dysfunction. Bioactivity of E. longifolia is antiosteoporotic, antimicrobial, aphrodisiac, anticancer, angiogenesis, and hepatoprotective. Eurycomanone has activity as an antimalaria, antipyretic, aphrodisiac, and cytotoxic. The quassinoids, coumarin and glycosides of El have activity increase the production, quality, totality, synthesis and release of spermatozoa. Eurycoma longifolia is very potential to be developed as an antiosteoporotic and aprosidiac drug, but until now most of it is harvested directly from the forest, so to preserve it, we need to study the cultivation method.

scholarly journals Relationships For The Utilization Of Pasak Bumi Plants (eurycoma longifolia Jack.) As A Traditional Medicine And Its Bioactivity

2020 ◽  
Vol 1 (2) ◽  
pp. 36-43
Author(s):  
Marina Silalahi
Keyword(s):  
Traditional Medicine ◽  
Production Quality ◽  
Cultivation Method ◽  
Eurycoma Longifolia ◽  
Review Articles ◽  
On Line ◽  
Eurycoma Longifolia Jack

Pasak bumi (Eurycoma longifolia Jack.) is a species belonging Simarobuaceae hasbeen long used as traditional medicine, which known very well as aphrosidiac. Thestudies have been conducted to reveal the benefits of E. longifolia throughethnobotany, phyto- chemical, and bioessay approaches, but the review articles on theits utilization and bioactivity limited. This article is based on scien- tific articlespublished on line or off line, then synthesized so that to be information the relationshipbetween use and bioactivity. Ethno- botanyof E. longifolia have been used as amedicine for fever, ma- laria, improve stamina, diabetic, cancer, aphrodisiac, erectiledys- function. Bioactivity of E. longifolia is antiosteoporotic, antimicro- bial,aphrodisiac, anticancer, angiogenesis, and hepatoprotective. Eurycomanone issecondary metabolites in E, longifolia has activi- ty as an antimalaria, antipyretic,aphrodisiac, and cytotoxic. The quassinoids, coumarin and glycosides of El haveactivity increase the production, quality, totality, synthesis and release of spermato-zoa. Eurycoma longifolia is very potential to be developed as an antiosteoporotic andaprosidiac drug, but until now most of it is harvested directly from the forest, so topreserve it, we need to study the cultivation method.

scholarly journals Penambatan Molekul Kandungan Eurycoma longifolia Jack. (Pasak bumi) terhadap Human Phosphodiesterase 5

2020 ◽  
Vol 7 (2) ◽  
pp. 36
Author(s):  
Samsul Hadi ◽  
Khoerul Anwar ◽  
Amalia Khairunnisa ◽  
Noer Komari
Keyword(s):  
Erectile Dysfunction ◽  
Molecular Docking ◽  
Traditional Medicine ◽  
Molecular Mechanism ◽  
Method Validation ◽  
Validation Method ◽  
Eurycoma Longifolia ◽  
Eurycoma Longifolia Jack ◽  
Phosphodiesterase 5

Pasak bumi sebagai obat tradisional pria telah digunakan oleh masyarakat melayu, khususnya orang Sumatra dan kalimantan, akan tetapi mekanisme secara molekuler belum dikatahui dengan jelas. Salah satu pendekatan yang dapat digunakan untuk mengetahui mekanisme pasak bumi sebagai obat tradisional yang bermanfaat mengatasi disfungsi ereksi adalah penambatan molekul. Penambatan melekul dilakukan dengan cara melihat interaksi ligand dengan reseptor. Ligand yang berasal dari pasak bumi adalah 5-methoxycanthin-6-one, 9-methoxycanthin-6-one, eurycomalactone, eurycomalide A, eurycomanone, eurycomaoside, laurycolactone A, longilactone, niloticin, picrasidine O. Sehingga kesepuluh ligand ini didocking menggunakan salah satu aplikasi docking yaitu PLANTS 1.1 untuk melihat ikatan dengan PDE5. Sebelum dilakukan docking terhadap ligand pasak bumi, terlebih dahulu dilakukan docking terhadap ligand Sildenafil untuk melhat nilai RMSD. RMSD ini diperlukan sebagai alat validasi metode, berdasarkan percobaan, nilai RMSD dari Sildenafil adalah 1,2517 A0. Hasil terbaik dari penambatan molekul pasak bumi adalah niloticin dengan skor doking -97,8802, sehingga nilai interaksinya terhadap reseptor sebesar 93,71% dari Sildenafil.Pasak bumi as traditional male medicine has been used by Malay people, especially Sumatra and Borneo people, but the molecular mechanism is not yet known clearly. One approach that can be used to determine the mechanism of the Pasak Bumi as a traditional medicine that is useful to overcome erectile dysfunction is docking molecules. Molecular docking is done by looking at the interaction of ligands with receptors. Ligands originating from the Pasak Bumi are 5-methoxycanthin-6-one, 9-methoxycanthin-6-one, eurycomalactone, eurycomalide A, eurycomanone, eurycomaoside, laurycolactone A, longilactone, niloticin, picrasidine O. docking application namely PLANTS 1.1 to see the bond with PDE5. Before docking Pasak Bumi ligand, it is first docking Sildenafil ligand to see the RMSD value. The RMSD is needed as a method validation method, based on experiments, the RMSD value of Sildenafil is 1.2517 A0. The best results from docking of the Pasak bumi molecule is niloticin with a doctor score of -97.8802, so interaction skor to the receptor is 93.71% of Sildenafil.Keywords: Pasak Bumi, PDE5, PLANTS

scholarly journals Page Header User You are logged in as... mike My Journals My Profile Log Out Notifications View (8 new) Manage Journal Content Search Search Scope Browse By Issue By Author By Title Other Journals TOOLS Flag Counter Keywords Bax Clopidogrel Eurycoma longifolia Jack root adherence analysis antiplatelet antithrombotic aspirin atenolol breast cancer co-chemotherapy cream customer satisfaction freshwater fish hypertension liposome orally disintegrating tablet (ODT) ratio of total cholesterol/HDL sodium starch glycolate sonication ticlopidine About The Authors Sesilia Effendy Universitas Sanata Dharma Indonesia Maria Felicia Gunawan Universitas Sanata Dharma Indonesia Daniel Lintang Adhi Argoputra Universitas Sanata Dharma Indonesia YB Abraham Universitas Sanata Dharma Indonesia Patricia Dian Anggraeni Universitas Sanata Dharma Indonesia Fenty Fenty Universitas Sanata Dharma Indonesia Home About User Home Search Current Archives Announcements Contact Home > Vol 15, No 1 (2018) > Effendy THE RELATIONSHIP BETWEEN PHYSICAL ACTIVITY AND OBESITY BASED ON BODY FAT PERCENTAGE IN BANJAROYO VILLAGE, KALIBAWANG, KULON PROGO, D.I. YOGYAKARTA

2018 ◽  
Vol 15 (1) ◽  
pp. 29-36
Author(s):  
Sesilia Effendy ◽  
Maria Felicia Gunawan ◽  
Daniel Lintang Adhi Argoputra ◽  
YB Abraham ◽  
Patricia Dian Anggraeni ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Orally Disintegrating Tablet ◽  
Eurycoma Longifolia ◽  
Sodium Starch Glycolate ◽  
Content Search ◽  
Eurycoma Longifolia Jack ◽  
Journal Content ◽  
The Relationship

scholarly journals Kajian Ekologi dan Potensi Pasak Bumi (Eurycoma longifolia Jack.) di Kelompok Hutan Sungai Manna-Sungai Nasal, Bengkulu

2016 ◽  
Vol 12 (2) ◽  
pp. 69
Author(s):  
N. M. Heriyanto ◽  
Reny Sawitri ◽  
Endro Subiandono
Keyword(s):  
Traditional Medicine ◽  
Diversity Index ◽  
Local People ◽  
Eurycoma Longifolia ◽  
The Third ◽  
Predominant Species ◽  
Dry Areas ◽  
Eurycoma Longifolia Jack ◽  
Index Value

<p>The study indicated that 88 species found belonged to 29 families. The predominant species was Shorea parvifolia (meranti) and Dipterocarpus costulatus (keruing). The highest dominance value belonged to second transect (0,0998) and the lowest dominant value was the fourth transect (0,0526). The highest diversity index value belonged to fifth transect (2,28) and the lowest of diversity index value was fourth transect (1,41). The abundance of pasak bumi was different in transect, for trees level it was 2 individuals/ha (first transect and third transect), however, in the second, fourth and fifth transect were none. For belta level, it was 10 individuals/ha (the first transect), 20 individuals/ha (the third transect) and 20 individuals/ ha (the fifth transect), while in the second and fourth transect were none. For seedling level it was 280 individuals/ ha (the third transect), 60 individuals/ha (the fourth transect) and 100 individuals/ha (the fifth transect), while in the first and the second were none. This intolerant species was adapted in slope and dry areas. The rarity of pasak bumi was not affecting local people because they were seldom used for traditional medicine.</p><p> </p><p><strong>Abstrak</strong></p><p>Dari hasil penelitian dijumpai 88 jenis tumbuhan yang termasuk ke dalam 29 famili. Jenis tumbuhan yang mendominasi tegakan adalah Shorea parvifolia (meranti) dan Dipterocarpus costulatus (keruing). Nilai dominansi tertinggi tingkat pohon dimiliki oleh jalur II (0,0998) dan terendah pada jalur IV (0,0526). Nilai indeks keanekaragaman jenis tertinggi di tingkat ini dimiliki oleh jalur V (2,28) dan terendah pada jalur IV (1,41). Kelimpahan pasak bumi pada setiap jalur berbeda-beda, untuk tingkat pohon adalah 2 pohon/ha pada jalur I dan jalur III. Pada jalur II, IV, dan V tidak dijumpai jenis pohon pasak bumi. Pada tingkat belta dijumpai 10 individu/ha pada jalur I, 20 individu/ha pada jalur III, dan 20 individu/ha pada jalur V. Pada jalur II dan IV tidak dijumpai jenis pasak bumi. Pada tingkat semai dijumpai 280 individu/ha pada jalur III, 60 individu/ ha pada jalur IV, dan jalur V memiliki kelimpahan 100 individu/ha. Pada jalur I dan II tidak dijumpai jenis pasak bumi. Tempat tumbuh yang disukai oleh pasak bumi adalah tanah miring dan tidak pernah tergenang air. Tumbuhan muda tidak toleran pada cahaya langsung. Ancaman terhadap kelangkaan pasak bumi di Bengkulu tidak terlalu merisaukan karena masyarakat setempat jarang yang memanfaatkannya untuk obat tradisional.</p><p> </p>

The relationship between serum irisin levels and erectile dysfunction in diabetic men (irisin and erectile dysfunction in diabetic patients)

Andrologia ◽  
2021 ◽  
Author(s):  
Şükrü Kumsar ◽  
Özlem Ciğerli ◽  
Eray Hasırcı ◽  
Ali F. Akay ◽  
Levent Peşkircioğlu
Keyword(s):  
Erectile Dysfunction ◽  
Diabetic Patients ◽  
The Relationship

scholarly journals System for Visualizing Surface Potential Distribution to Eliminate Electrostatic Charge

Sensors ◽  
2021 ◽  
Vol 21 (13) ◽  
pp. 4397
Author(s):  
Kazuya Kikunaga
Keyword(s):  
Surface Potential ◽  
Potential Distribution ◽  
Measurement Accuracy ◽  
High Spatial Resolution ◽  
Scanning Speed ◽  
Electrostatic Charge ◽  
Production Quality ◽  
Array Sensor ◽  
The Relationship ◽  
Non Destructive

A mixture of positive and negative static charges exists in the same plane on an insulator surface, and this can cause production quality problems at manufacturing sites. This study developed a system with a vibration array sensor to rapidly measure the surface potential distribution of an object in a non-contact and non-destructive manner and with a high spatial resolution of 1 mm. The measurement accuracy differed greatly depending on the scanning speed of the array sensor, and an optimum scanning speed of 10 mm/s enabled rapid measurements (within <3 s) of the surface potential distribution of a charged insulator (area of 30 mm × 30 mm) with an accuracy of 15%. The relationship between charge and dust on the surface was clarified to easily visualize the uneven static charges present on it and thereby eliminate static electricity.

scholarly journals The Animation of Gamers and the Gamers as Animators in Sierra On-Line’s Adventure Games

Animation ◽  
2021 ◽  
Vol 16 (1-2) ◽  
pp. 83-95
Author(s):  
Raz Greenberg
Keyword(s):  
Video Games ◽  
Digital Games ◽  
Free Play ◽  
Digital Gaming ◽  
Adventure Game ◽  
Adventure Games ◽  
Software Publisher ◽  
On Line ◽  
The Relationship

Produced throughout the 1980s using the company’s Adventure Game Interpreter engine, the digital adventure games created by American software publisher Sierra On-Line played an important and largely overlooked role in the development of animation as an integral part of the digital gaming experience. While the little historical and theoretical discussion of the company’s games of the era focuses on their genre, it ignores these games’ contribution to the relationship between the animated avatars and the gamers that control them – a relationship that, as argued in this article, in essence turns gamers into animators. If we consider Chris Pallant’s (2019) argument in ‘Video games and animation’ that animation is essential to the sense of immersion within a digital game, then the great freedom provided to the gamers in animating their avatars within Sierra On-Line’s adventure games paved the way to the same sense of immersion in digital. And, if we refer to Gonzalo Frasca’s (1999) divide of digital games to narrative-led or free-play (ludus versus paidea) in ‘Ludology meets narratology: Similitude and differences between (video) games and narrative’, then the company’s adventure games served as an important early example of balance between the two elements through the gamers’ ability to animate their avatars. Furthermore, Sierra On-Line’s adventure games have tapped into the traditional tension between the animator and the character it animated, as observed by Scott Bukatman in ‘The poetics of Slumberland: Animated spirits and the animated spirit (2012), when he challenged the traditional divide between animators, the characters they animate and the audience. All these contributions, as this articles aims to demonstrate, continue to influence the role of animation in digital games to this very day.

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