Penerapan Metode Kanguru Terhadap Kenaikan Berat Badan Pada Bayi Berat Lahir Rendah : Lirature Riview

One of the non-pharmacoiogicai therapies given to stabiiize low-weight newborns is the Kangaroo Care. This study aimed to describe the application of Kangaroo Care in lowweight newborns. The study was a literature review of three chosen articles taken from Google Scholar with the keywords "kangaroo method", "weight gain" and "low-weight newborns" .in the form of fulltext articles published during 2015 — 2018. The result showed that from 47 newborn who were treared as respondents, most of them (59,3%) were female, and 62,9% aged 1-3 days. The average body weight before being treated with the Kangaroo Care was 1876.83 grams and it raised to 2120.18 grams after the treatment. The conclusion was that the kangaroo care could increase body weight of low-weight newborns. Hence, health providers are expected to introduce the Kangaroo Care as an alternative of weight gain treatment for low weight newborn. Keywords: kangaroo method, weight gain, low-weight newborns AbstrakSalah satu terapi nonfarmakologis untuk menaikan berat badan bayi baru lahir rendah adalah perawatan metode kanguru. Penelitian ini bertujuan untuk menggambarkan perawatan metode kanguru pada bayi baru lahir rendah. Desain karya tulis ilmiah berupa literur review dengan jumlah tiga artikel diambil dari laman google scholar dengan kata kunci “metode kanguru” “kenaikan berat badan” dan “BBLR” berupa artikel full text, terbit tahun 2015-2018. Hasil analisa karakteristik responden dari tiga artikel menunjukkan jumlah responden 47, sebagian besar (59,3%) perempuan, 62,9% umur 1-3 hari. Nilai rata-rata berat badan sebelum dilakukan perawatan metode kanguru 1876,83 gram, setelah dilakukan perawatan metode kanguru 2120,18 gram. Kesimpulannya adalah perawatan metode kanguru dapat menaikan berat badan pada bayi baru lahir rendah. Saran bagi pelayanan kesehatan hendaknya mengedukasi tentang perawatan metode kanguru sebagai salah satu alternatife untuk kenaikan berat badan pada bayi baru lahir rendah.Kata kunci: metode kanguru, kenaikan berat badan, BBLR

The Role of SGLT-2 Inhibitors as an Adjuvant to Insulin Therapy in Type-1 Diabetes Mellitus- Literature Review

Background: Type 1 diabetes mellitus is the main risk factor for cardiovascular complications. Therefore, intensified insulin therapy might be needed to achieve better glycemic control in some patients. However, insulin therapy might lead to increase body weight and induce hypoglycemia. Increase body weight is directly correlated to insulin resistance, the main factor for cardiovascular risk. Objective: To assess the effectiveness of adding SGLT2 inhibitors to insulin therapy in type 1 diabetes mellitus. Methods: We searched in the PubMed database looking for relevant articles on the topic. We used Mesh words search, including SGLT2 inhibitor, sotagliflozin, type 1 diabetes mellitus, insulin treatment. Conclusion: Adding oral antidiabetic agents, such as SGLT2 or dual SGLT inhibitors to insulin regimen might be beneficial in improving insulin resistance. Thus, it achieved better insulin resistance by decrease daily insulin requirements and bodyweight control, leading to better cardiovascular outcomes among Type-1 diabetes patients.

Protective Effects of Almond Oil on Streptozotocin-Induced Diabetic Rats via Regulating Nrf2/HO-1 Pathway and Gut Microbiota

Almond oil has been used as a medicine substitution for its numerous health benefits. This study aimed to evaluate the effect of almond oil on streptozotocin- (STZ-) induced diabetic rats for 4 weeks. The results showed that the administration of almond oil could significantly increase body weight, attenuate abnormally elevated blood glucose, promote insulin secretion, and improve glucose tolerance. Almond oil treatment also suppressed oxidative stress, reduced inflammation reaction, improved liver and kidney function, upregulated the expressions of Nrf2, HO-1, and NQO1, while downregulating the expression of Keap1. Furthermore, almond oil reversed the gut microbiota change by STZ and regulated the gut microbiota associated with glucose metabolism. At the phylum level, the relative abundance of Firmicutes was decreased, while Bacteroidetes was increased by almond oil treatment. More importantly, the ratio of Firmicutes/Bacteroidetes was significantly increased. At the genus level, administration of almond oil increased the abundances of Lactobacillus, Bacteroides, and Lachnospiraceae_NK4A136_group, while decreased the abundances of Ruminococcaceae_UCG-014, Clostridium_sensu_stricto_1, and Fusicatenibacter. These results provided evidence for the regulating effect of almond oil on diabetic rats via the Nrf2/HO-1 pathway and gut microbiota.

Vitamin D and Alcohol Differentially Effect Weight Gain in Older Female Mice

Objectives Serum calcidiol is inversely associated with BMI in obese individuals and murine research has shown that vitamin D deficient diets (VDD) increase body weight. Alcohol intake doesn't necessarily increase body weight despite its caloric density but has been associated with VDD. The objective of this study was to determine the effect of vitamin D deficiency with or without alcohol on body weight, body composition, glucose tolerance, and energy expenditure in seven-month-old female mice. Methods Seven-month-old female retired breeder C57BL/6J mice (n = 40) were weight-matched and randomized to one of four diets: control (normal purified AIN-93 diet), vitamin D deficient (VDD, 0 intake of vitamin D), alcohol (Alc, 10% ethanol), or vitamin D deficient and alcohol (VDD + Alc). Mice were fed ad libitum for 8 weeks. Body weight and food intake were recorded weekly and body composition was measured at baseline and final time points using EchoMRI. Glucose tolerance and energy expenditure (EE) were assessed by an oral glucose tolerance test (OGTT) and Oxymax/CLAMS unit at week 8. Results Body weight at baseline was 27.4 ± 1.8 g and did not differ between groups. Mice drinking alcohol had a decreased food intake (p < 0.001). When liquid calories were accounted for, total caloric intake did not differ between groups. Weight gain throughout the study increased more in the VDD groups (p < 0.05). Increases in weight were 0.81 ± 2.9, 0.82 ± 2.0, 2.0 ± 1.7, and 3.6 ± 2.9 g, in the control, Alc, VDD, and VDD + Alc groups, respectively (p < 0.05). Lean body mass was also increased due to VDD (p < 0.05). The total fat mass did not differ significantly between groups, however, VDD groups gained more fat mass over time (p < 0.05). Two-way ANOVA showed an interaction between vitamin D and alcohol for EE (p < 0.05). Positive incremental area under the curve (IAUC) for blood glucose was decreased due to alcohol intake (p < 0.05). Conclusions In conclusion, alcohol intake decreased blood glucose and food intake, but there was no effect on total caloric intake, body weight or body composition. VDD led to greater increases in body weight and soft tissue compartments compared to other groups that were not explained by caloric intake or EE. Understanding mechanisms that are causing excess weight gain due to VDD is currently a focus in the lab. Funding Sources USDA-NIFA (NJAES).

The Effect of Baby Massage on Improvement Baby Weight

The problem experienced by toddlers is that growth disorders in Indonesia have started to emerge from children aged 1-6 months, so that efforts are needed to reduce the rate of growth disorders or to or to increase weight presentation. Increasing body weight is an indicator of infant health that can be used as a benchmark for infant growth. Body weight is the most important anthropometric measure and is most often used in newborns (neonates). One of the treatments that can be done to increase body weight is by giving massage to babies. Baby massage can stimulate the penvernaan hormones insulin and gaselin, so that food absorption becomes better. This causes babies to feel hungry quickly so they eat more often and gain weight. The purpose of this study was to determine the effect of infant massage on infant weight gain. The method in this study is a literature review, which tries to explore how the effect of infant massage on infant weight gain. The results in this study indicate that the results of 6 previous studies indicate that there is a significant effect of infant massage on the increase in infant body weight. The conclusion in this study is that massage in infants can increase the baby's weight. This is because the massage that is carried out regularly on babies is used to massage the legs, stomach, chest, hands, back, and stretching movements can increase the baby's weight. The massage will cause nerve action potential that stimulates the vagus nerve.

Efficiency the Utilization of Folow up Palm Plants foor Increasing Production Beef Cattle in District Pasaman Barat

The main problem in the development of cattle business people in palm plantation, one exeption availibility of forage animal feed whether in quantity n quality. Other side the existence of palm leaves the midrib has been waste of a disturbing and not been utilized by farmers. To the touch technological innovations feed in te form of silage then palm leaves the midrib has been animal feed worthy of in eating of cattle. The purpose of this research is identify the effects the provisio of feed based silage palm leaves midrib increased body weight on cattle beef and analyzing efficiency the cost of animal feed. Research in farmer group Tanjung Keramat in district Kinali, Pasaman Barat in february until april 2017. Respondent are set down in purposive sampling. This research used 18 tail local bulls created the average 2 until 2, 5 years. Treatment provides was P1 control grass field is 10% from body weght (25 Kg) + bran is 10% from body weght (2,5 Kg) , P2 granting of silage then palm leaves (10 kg) + bran (1,5 Kg) + gliserida ( 2 Kg). In an analysis using t tableindependent sample t-testα=5%. Result of research shows P1 increase body weight cattle 0,68 kg/tail/day and P2 0,81 kg/ tail/ day . Provision of feed based silage then palm leaves significant compared feed control t test (-6,9) > t tabel (2,4). With efficiency cost feed during 90 days P1 (Rp. 967.500,-/cattle) and P2 (Rp. 675.500,-/cattle). So, with provision palm leaves besides increasing body weight cattle, can also reducing the grass that drain time dan energy can reduce the cost daily cattle feed.

Effects Of Orally Administered Recombinant Lactobacillus Casei Expressing HN Protein On Early Growth Performance, Intestinal Health And Protection Against NDV Challenge In Chickens

Backgroud: Newcastle disease virus (NDV) is considered one of the most important diseases among chickens. In this study, we generated recombinant surface-displayed Lactobacillus casei (L.casei) expressing the hemagglutinin-neuraminidase (HN) of NDV and a live vector pPG alone (named Lc-pPG-HN and Lc-pPG), and evaluated their effects on early growth development, intestinal health and protection against NDV challenge in chickens. 270 chickens were randomly divided into three groups: Lc-pPG-HN, Lc-pPG and physiological saline (control) group, and chickens from each group were respectively immunized with Lc-pPG-HN, Lc-pPG and physiological saline on 1 and 10 days. Results: Recombinant L.casei expressing the HN protein of NDV (Lc-pPG-HN) was successfully constructed. Orally immunized with Lc-pPG-HN could significantly increase body weight (BW) and immune organs index. Moreover, Lc-pPG-HN improved secretory immunoglobulin A (SIgA) in jejunum, the relative abundance of flora in cecum, histomorphological development of small intestine. In addition, the similar enhancement effects were also observed with hemaggluti-nation inhibition (HI) antibody titer and the expression of cytokines in the serum. The oral administration of Lc-pPG-HN also provided effective protection and alleviated the symptoms of NDV challenge.Conclusions: Thus, a recombinant L.casei vaccine expressing HN may be a potential therapeutic candidate against NDV and improve chickens growth and development.

Sistematik Review: Kriteria dan Peran Pengawas Menelan Obat Pasien Tuberculosis di Indonesia

Indonesia falls into the category of countries with the highest TB case burden. This number will continue to increase if the number of TB patient care is not implemented properly. Non- compliance with treatment is a separate problem in the success of TB elimination. The role of Supervisor for Drug Swallowing/Pengawas Menelan Obat (PMO) is one of the factors that support the success of TB treatment. The purpose of this study was to determine the criteria and role of supervisors to swallow drugs in tuberculosis patients in Indonesia. Two article search engines were used, namely GARUDA (Garba Rujukan Digital) and Neliti. There are 14 types of research identified, with details of 10 quantitative studies and 4 qualitative studies. The expected criteria of the Supervisor for Drug Swallowing/Pengawas Menelan Obat (PMO) are over 17 years old, female, not working, minimum high school education having kinship relations, living at home, and if the supervisor swallows drugs is a health worker then has better knowledge about tuberculosis treatment and empowerment of TB patients to form a self group. The role of Supervisor for Drug Swallowing/Pengawas Menelan Obat (PMO) in Indonesia includes ensuring patients swallow drugs every day, become educators, accompany control patients to health care centers, remind patients to check recurrent phlegm, provide moral support to patients, take patients to health care centers if drug side effects occur, improve preventive behavior and increase body weight.

Pengaruh pemanfaatan ampas kedelai dan onggok terfermentasi rhizopus sp dalam konsentrat domba Merino terhadap pertambahan bobot badan dan konsumsi pakan

ABSTRACT This study aims to determine the benefits of soybean husk and onggok fermented rhizopus sp in feed merino sheep concentrate of body weight gain and feed intake. Materials used in the study is as much as 12 merino sheep and the methods used by the randomized trial (RAK) using the PO as controls (100% concentrate); P1 (AOT concentrate 90% + 10%); P2 (AOT concentrate 80% + 20%); P3 (AOT Concentrate 70% + 30%). The results of the study with 30% of AOT gift giving weight increase of 25.3 g / tail significantly different (F count> F table) and feed consumption P0 :. 215, 27g / tail, P1 : 203, 13g / eco, P2: 219,24g / tail, P3: 190.72 not significantly different (F arithmetic <F table 0.05), it can be concluded that the AOT replace concentrate when substituted have the same content to concentrate on P0 , P1, P2, and P3. From the results of this study cuncluded that the addition soybean husk and onggok fermented rhizopus sp in feed merino sheep concentrate can increase body weight gain and low consumption level but have a good nutrition with the level of gift 30%. ABSTRAK Penelitian ini bertujuan untuk mengetahui manfaat dari kulit kedelai dan onggok fermentasi Rhizopus sp dalam pakan merino domba konsentrat dari bobot badan dan konsumsi pakan. Bahan yang digunakan dalam penelitian ini adalah sebanyak 12 domba dan metode yang digunakan oleh uji coba secara acak (RAK) dengan menggunakan PO sebagai kontrol (100% konsentrat); P1 (AOT berkonsentrasi 90% + 10%); P2 (AOT berkonsentrasi 80% + 20%); P3 (AOT Konsentrat 70% + 30%). Hasil penelitian dengan 30% dari hadiah AOT memberikan peningkatan berat 25,3 g / ekor yang berbeda secara signifikan (F hitung> F tabel) dan pakan P0 konsumsi:. 215, 27g / ekor, P1: 203, 13 g / eco, P2: 219,24g / ekor, P3: 190,72 tidak berbeda nyata (F hitung <F tabel 0,05), dapat disimpulkan bahwa AOT menggantikan konsentrat ketika diganti memiliki konten yang sama untuk berkonsentrasi pada P0, P1, P2, dan P3. Dari hasil penelitian ini diaimpilkan bahwa penambahan kulit kedelai dan onggok fermentasi Rhizopus sp dalam pakan konsentrat domba merino dapat meningkatkan bobot badan dan tingkat konsumsi yang rendah tetapi memiliki gizi yang baik dengan tingkat pemberian 30%.

PENGARUH SUPLEMENTASI DL-METIONIN DAN L-LISIN HCL PADA PAKAN STANDAR KAFETARIA TERHADAP BERAT BADAN, ORGAN DALAM DAN ORGAN REPRODUKSI AYAM KAMPUNG FASE PULLET

The aim of this study was to determine the effect of the supplementation of dl-methionine and l-lysine HCl to diet based on cafeteria standards of native chickens on body weight, internal organs and reproductive organs of native chicken at pullet phase. A total of 128 fourteen weeks-old native chickens were used in this study. The native chickens were divided into 4 treatments with 4 replications. The dietary treatments were: T0 (ration based on cafeteria standard), T1 (ration based on protein standard of NRC), T2 (cafeteria ration+0.09% DL-Methionine+0.22% L-Lysine HCl), T3 (cafeteria ration+0.19% dl-methionine+0.42% l-lysine HCl). The data collected were body weight, liver and bile, pancreas, gizzard, testicular and ovary weight of native chickens aged 20 weeks. The result of this study for T0, T1, T2 and T3 showed that body weight of chickens were 1418.60; 1431.59; 1503.88 and 1556.41 g/bird, liver and bile weights were 22.44; 21.79; 24.49 dan 25.93 g/bird, pancreas weights were 2.33; 2.28; 2.50 and 2.70 g/bird, gizzard weight were 25.31; 23.91; 25.38 and 26.86 g/bird, testicular weight were 3.66; 3.86; 9.55 and 9.46 g/bird, testicular volume were 3.81; 3.38; 9.13 and 9.16 and ovary weight were 1.12; 1.32; 3.14 and 4.61 g/bird, respectively. The results showed that supplementation of DL-Methionine and L-Lysine HCl gave significantly effect (P<0.05) upon body weight, liver and bile weight, pancreas weight, testicular weight and volume and ovary weight, but it did not effected to gizzard weight. It can be concluded that supplementation of 0.27% dl-methionine and 0.79% l-lysine HCl increase body weight, internal organs weight and reproductive organs weight of native chickens. Keywords: Cafeteria, DL-Methionine, L-Lysine HCl, Native Chicken, Supplementation.