scholarly journals Leukocyte Count, CRP and Bilirubin Level in Complicated and Non-Complicated Appendicitis: Cross Sectional Study

2017 ◽  
Vol 4 (3) ◽  
Author(s):  
Caloska-Ivanov V
2017 ◽  
Vol 8 (2) ◽  
pp. 56-58
Author(s):  
Garima Biyani ◽  
Swapan Kumar Ray ◽  
Kripasindhu Chatterjee ◽  
Sukanta Sen ◽  
Pradyut Kumar Mandal ◽  
...  

Background: Febrile convulsion (FC) is the most common seizure disorder in childhood. White blood cell (WBC) and C reactive protein (CRP) are commonly measured in FC. Add a paragraph on Aims and Objectives of the study.Aims and Objectives: To compare WBC and CRP in febrile children, aged 6 months to five years, with and without FC, in order to determine whether leukocytosis and elevated CRP can be used as diagnostic tool for febrile seizure.Materials and Methods: In this cross sectional study 214 children (112 with FC), aged 6 months to 5 years, admitted to in the first 48 hours of their febrile disease, either with or without seizure, were evaluated over a 12 months period. Age, sex, temperature; WBC, CRP and hemoglobin were recorded in all children. There was a significant increase of WBC (P<0.001) in children with FC so we can deduct that leukocytosis encountered in children with FC can be due to convulsion in itself.Results: When comparing FC and non-FC children, we encountered a significant increase of WBC (P =0.0005) in children with FC, measured at the time of admission to pediatric medicine ward. There was no significant difference regarding CRP between the two groups. In fact, elevated CRP is a result of underlying pathology.Conclusion: In stable patients, if there’s no reason to suspect a bacterial infection or who don’t have any indication of lumbar puncture, there’s no need to assess WBC as an indicator of underlying infection. Any child with febrile seizure with a high CRP value should be evaluated for infection.Asian Journal of Medical Sciences Vol.8(2) 2017 56-58


Author(s):  
Poonam Kumari ◽  
Ram Gopal Nautiyal ◽  
HK Thakar

Introduction: Asthma is a heterogenic disease, commonly divided into allergic and nonallergic asthma. It affects people of all age group and is associated with impaired lung function. Previously, it was thought that asthma is a disease of developed countries but at present, world scenario has changed and its prevalence in developing countries is rapidly increasing. Asthma shows large geographical variations in terms of prevalence, severity and mortality. Aim: To establish the prevalence of allergic and nonallergic asthma in adults of Kumaun region of Uttarakhand (India) and to evaluate whether the peripheral blood cell count is associated with the severity of lung impairment in both the subtypes (allergic and nonallergic) of asthma. Materials and Methods: This cross-sectional study was carried out jointly in Department of Physiology and Department of Respiratory Medicine, Government Medical College, Haldwani, Uttarakhand (India), during the period from October 2015 to January 2017. A total of 125 patients of both sexes age above 18 years, who attended the OPD of Respiratory Medicine and diagnosed asthma by the physician were enrolled in the study. The patients associated with tuberculosis, worm infestations, other allergic diseases and systemic diseases were excluded. History of Allergic Rhino-Conjunctivitis (ARC) was used for allergic sensitisation and to define allergic asthma. Classification of severity of airflow limitation was done according to Global Initiative for Asthma (GINA) guidelines. Absolute Leukocyte Counts was determined by using the formula: Absolute leukocyte count=Differential leukocyte count/100×Total leukocyte count. One-way ANOVA followed by Tukey HSD post-hoc analysis and Chi-square was done. Level of statistical significance was set at p-value <0.05. Results: The prevalence of allergic asthma was more in 79 patients (63.2%), in comparison to nonallergic asthma in 46 (36.8%) and it (allergic asthma) was more common in males than females (54:25). Mean age of allergic and nonallergic group asthma patients were 51.00±14.31 and 56.11±13.14 years, respectively. In allergic asthma patients, blood eosinophil count increased significantly (p=0.001) the severity of lung impairment increased and no significant changes were observed in other blood cell counts while in nonallergic asthma over-all neutrophil count was significantly high (p=0.044) with increase in severity. Nonallergic asthma also showed increasing trend of eosinophil count as the severity of airway obstruction increased but there were no significant changes in other counts. Conclusion: The prevalence of allergic asthma is high in comparison to nonallergic asthma among adults of Kumaun region of Uttarakhand, India and it is more prevalent among males in both the groups. Peripheral blood leukocyte count might be used as biological marker to differentiate allergic asthma from nonallergic asthma.


2021 ◽  
Vol 6 (1) ◽  
pp. 43-47
Author(s):  
Reza Hajebi ◽  
Hadi Ahmadi Amoli ◽  
Hossein Zabihi Mahmoudabadi ◽  
Ehsan Rahimpour ◽  
Khosro Najjari ◽  
...  

Background: Using hematologic profiles including leukocyte count have been considered as prognostic factor for some cancers. We have been assessed the predictive value of leukocytosis before surgery in colorectal cancers.Methods: This cross-sectional study has been conducted on patients with colorectal cancer who underwent surgery from 2017 to 2019 in Sina hospital, Tehran. The patients were divided in two groups based on high and low leukocyte count before surgery. Results: A total of 84 patients were studied with colorectal cancers including 46 males (55.4%) and 37 females (44.6%) with the average age of 55.2 (± 13.63) years. 36.1% of patients had leukocytosis in laboratory data before surgery. There was a significant association between tumor’s grade and the incidence of leukocytosis before surgery (P <0.001). The existence of leukocytosis is highly associated with poorly differentiated tumor. Also, the relationship between the location of the tumor and leukocytosis was seen which the location was distal, the possibility of leukocytosis decreased significantly (P <0.005). Conclusion: Our findings suggest that the location of the tumor and its degree of tumor differentiation are related with leukocytosis. This current study by considering leukocytosis before surgery aimed to use this variable as a prognostic factor in patients with colorectal cancer alongside with other variables.


Author(s):  
ARUN SINGH TEJAVATH ◽  
AMIT MATHUR ◽  
PRATIMA SINGH ◽  
SUPRIYA SUMAN ◽  
PREETI RAJ ◽  
...  

Objective: The objective of the study was to describe, evaluate, and analyze neurological manifestation in human immunodeficiency virus HIV positive patients admitted to a tertiary care center. Methods: The study was a prospective cross-sectional study, in which 103 HIV patients were analyzed. All patients were interviewed face to face and evaluated by the investigator with particular reference to neurological manifestations. They were classified into various stages of HIV using the World Health Organization staging system. Results: The mean age in males was 37 (standard deviation [SD] 8.0) years and in females 35 (SD 7.0) years. A greater proportion of females were diagnosed in the asymptomatic state during screening, either during pregnancy or when the spouse was found to be positive. Headache was the most common neurologic symptom and fundus abnormalities were the most common neurological sign documented in patients. The mean CD4 counts in males are 156.5/mm3 and in females are 229.57/mm3 whereas the mean absolute leukocyte count in males is 1088.30/mm3 and in females is 1473.52/mm3. The CD4 counts showed a better correlation with the occurrence of neurological manifestations than absolute leukocyte count. Conclusion: Headache was a significant predictor of the occurrence of neurological complications (p=0.01). CD4 counts were significantly lower in patients with neurological complications and most of the neurological manifestations; on the contrary, all the opportunistic infections were documented in patients with CD4 counts below 200/mm3. Neurological complications did not show any correlation with the patient being on anti-retroviral therapy.


2020 ◽  
Vol 9 (30) ◽  
pp. 2129-2132
Author(s):  
Sreeramulu Patrapalli Nadipanna ◽  
Shashidhar Kurpad Nagaraj ◽  
Varsha Anand

2021 ◽  
Vol 28 (5) ◽  
pp. 130-136
Author(s):  
Hamzah Sukiman ◽  
◽  
Abdul Malek Mohamad ◽  
Muhammad Firdaus Nasution Raduan ◽  
Mohd Nur Afiq Mohd Yasim ◽  
...  

Background: Appendicitis is common and delayed presentation results in complicated appendicitis with increased morbidity. This study investigates the effect of the Movement Control Order (MCO) during the COVID-19 pandemic on the presentation and severity of appendicitis. Methods: A cross-sectional study including 193 patients diagnosed with appendicitis was conducted at four hospitals in Pahang, Malaysia. Those who presented between 1 February 2020 and 17 March 2020 were included in the pre-MCO group and those between 18 March 2020 and 30 April 2020 in the MCO group. The definitions of simple and complicated appendicitis were based on the Sunshine Appendicitis Grading Score. The primary outcome was the incidence of complicated appendicitis, and the secondary outcomes were length of stay, a composite of surgical morbidities and a composite of organ failure. Results: A total of 105 patients in the pre-MCO group and 88 in the MCO group were analysed. The incidence of complicated appendicitis was 33% and it was higher in the MCO than in the pre-MCO group (44% versus 23%, P = 0.002). The MCO period was independently associated with complicated appendicitis in the logistic regression (P = 0.001). It was also associated with prolonged length of stay (3.5 days versus 2.4 days, P < 0.001) and higher overall surgical morbidity (19% versus 5%, P = 0.002). Conclusion: The MCO imposed during the COVID-19 pandemic was associated with a higher incidence of complicated appendicitis and surgical morbidity.


2016 ◽  
Vol 25 ◽  
pp. 109-113 ◽  
Author(s):  
F.A. Alvarez-Alvarez ◽  
V.M. Maciel-Gutierrez ◽  
A.D. Rocha-Muñoz ◽  
J.H. Lujan ◽  
C.F. Ploneda-Valencia

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