scholarly journals Abnormal values of trace elements and blood metals in patients with metabolic syndrome, depending on its components

2019 ◽  
Vol 91 (10) ◽  
pp. 70-75
Author(s):  
V I Podzolkov ◽  
T V Korolyova ◽  
M G Kudryavtseva
Keyword(s):  
Metabolic Syndrome ◽  
Trace Elements ◽  
Inductively Coupled Plasma ◽  
Average Duration ◽  
Atomic Emission ◽  
Control Group ◽  
Positive Correlation ◽  
Inductively Coupled

Aim. To study the level of “toxic” (Al, Cd, Pb) and “essential” (Fe, Cu, Zn, Co, Cr, Ni, and Se) trace elements (TE) and blood metals (BM) in patients with metabolic syndrome (MS), depending on its individual components. Materials and methods. 112 patients with MS were examined (45 men and 67 women; average age 61.4±7.2 years, average duration of MS 8.7±5.2 years). The study of BM was carried out by atomic emission spectrophotometry with inductively coupled plasma . Results and discussion. To study the amount of TE and BM in the group of MS patients,it was significantly higher levels of “toxic” MEs - Al, Cd, Pb - were revealed along with a decrease in the content of the “essential” Zn element as compared to the control group. At the same time, a pronounced positive correlation between the fact of the presence of MS and the level of “toxic” microelements - Al (r=0.71; p

scholarly journals Levels of Trace Elements in Erythrocytes as Endocrine Disruptors in Obese and Nonobese Women with Polycystic Ovary Syndrome

2022 ◽  
Vol 19 (2) ◽  
pp. 976
Author(s):  
Kamila Pokorska-Niewiada ◽  
Agnieszka Brodowska ◽  
Jacek Brodowski ◽  
Małgorzata Szczuko
Keyword(s):  
Trace Elements ◽  
Polycystic Ovary Syndrome ◽  
Inductively Coupled Plasma ◽  
Polycystic Ovary ◽  
Atomic Emission ◽  
Thyroid Stimulating Hormone ◽  
Control Group ◽  
Obese Women ◽  
Ovary Syndrome ◽  
Inductively Coupled

Introduction: Polycystic ovary syndrome (PCOS) is one of the most commonly recognized endocrinopathies in women. The literature lacks clear data that allow any meaningful conclusions to be drawn about the influence of trace elements in erythrocytes on the biochemical parameters of PCOS. Materials and methods: This study was conducted among 47 women meeting the Rotterdam criteria for the diagnosis of polycystic ovary syndrome. The research groups included women with PCOS with different BMI values (body mass index): obese women with PCOS (PCOS with BMI ≥ 30, mean BMI index 35.4 ± 4.4 kg/m2), nonobese PCOS women (PCOS with BMI < 30, mean BMI index 25.2 ± 2.8 kg/m2), and healthy control group (CG) with a mean BMI of 23.57 ± 0.9 kg/m2. The contents of trace elements in erythrocytes were determined with an inductively coupled plasma atomic emission spectrometer. Results: The only trace element showing significant differences in concentration between the studied groups was nickel (Ni). The level of nickel in the obese women with PCOS (BMI ≥ 30) was significantly higher than in nonobese women (BMI < 30). The content of other trace elements in erythrocytes did not differ significantly between the studied groups. Several significant correlations were found within each of the studied PCOS groups: in the group of obese women, the content of zinc (Zn) in erythrocytes positively correlated with prolactin, the content of magnesium (Mg) positively correlated with testosterone, and the content of manganese (Mn) negatively correlated with thyroid-stimulating hormone. In the group of nonobese women, Zn content correlated positively with testosterone, Ni with luteinizing hormone (LH) and estradiol, and Mg negatively correlated with estradiol. Conclusions: The relationship between the level of trace elements and the level of hormones suggests that, in obese women with PCOS, nickel may play a role in inhibiting the processes of folliculogenesis and ovulation. Research on trace elements and their relationship to ovulatory cycles and the development of PCOS may contribute to reducing the consequences of PCOS and, therefore, should be extended.

scholarly journals Trace elements in patients with aortic valve sclerosis

2021 ◽  
Vol 15 ◽  
pp. 175394472098598
Author(s):  
Hataw Al-Taesh ◽  
Abuzer Çelekli ◽  
Murat Sucu ◽  
Seyithan Taysi
Keyword(s):  
Trace Elements ◽  
Aortic Valve ◽  
Inductively Coupled Plasma ◽  
Healthy Subjects ◽  
Serum Zinc ◽  
Serum Levels ◽  
Control Group ◽  
Aortic Valve Sclerosis ◽  
Inductively Coupled ◽  
Significant Difference

Background: Aortic valve sclerosis (AVSc) is defined as the thickening and calcification of aortic valve cusps, in the absence of obstruction of ventricular outflow. AVSc is linked with a clear imbalance in some trace elements. Aims: The objective of this study was to investigate the relationship between AVSc and serum levels of iron (Fe), zinc (Zn), selenium (Se), and copper (Cu). Additionally, this research aimed to explore the clinical significance of human serum zinc, selenium, copper, and iron concentrations as a potential new biomarker for AVSc patients and to clarify the pathophysiological role in individuals at risk of developing AVSc. Patients and methods: The study included 40 subjects with AVSc (25% male and 75% female) who were compared with a healthy control group with the same gender ratio. AVSc was based on comprehensive echocardiographic assessments. Blood samples were taken and Zn and Cu concentrations were determined through the use of atomic absorption spectroscopy. Se was measured using an inductively coupled plasma mass spectrometry device and Fe was measured using a Beckman Coulter instrument. Results: There was a significant difference in the prevalence of diabetes, blood pressure levels, and body mass index between the patients and the healthy subjects ( p < 0.05). The differences between the serum Fe, Se, and Cu levels of the AVSc patients and the healthy subjects ( p > 0.05) were recorded. The serum Zn of AVSc patients when compared was significantly lower compared with that of the control group ( p < 0.01). Conclusion: Patients with AVSc had an imbalance in some of the trace elements in their blood. The patient group’s valves had higher serum Cu levels and lower serum Se, Zn, and Fe concentrations compared with the healthy group’s valves. In the valve patients as compared, AVSc had a high prevalence of obesity, hypertension, and diabetes.

scholarly journals Trace elements and rat pouchitis.

2012 ◽  
Vol 59 (4) ◽  
Author(s):  
Sławomira Drzymała-Czyż ◽  
Tomasz Banasiewicz ◽  
Stanisław Walas ◽  
Tomasz Kościński ◽  
Ewa Wenska-Chyży ◽  
...  
Keyword(s):  
Trace Elements ◽  
Restorative Proctocolectomy ◽  
Inductively Coupled Plasma ◽  
Complete Removal ◽  
Control Group ◽  
Slight Reduction ◽  
Inductively Coupled ◽  
The Status ◽  
Plasma Mass Spectrometry ◽  
Inflammatory Changes

The procedure of restorative proctocolectomy is associated with a complete removal of the colon and slight reduction of ileum length, which together can lead to systemic shortages of trace elements. Inflammatory changes in the pouch mucosa may also have some impact. However, there is no data on trace elements in pouchitis. Therefore, in the present study we aimed to assess the effect of acute pouchitis on the status of selected trace elements in rats. Restorative proctocolectomy with the construction of intestinal J-pouch was performed in twenty-four Wistar rats. Three weeks after the surgery, pouchitis was induced. Eight untreated rats created the control group. Liver concentrations of selected micronutrients (Zn, Cu, Co, Mn, Se) were measured in both groups six weeks later, using inductively coupled plasma mass spectrometry. Liver concentrations of trace elements did not differ between the study and the control groups. However, copper, cobalt and selenium concentrations [μg/g] were statistically lower (p

A Comprehensive Review of Minerals, Trace Elements, and Heavy Metals in Saffron

2022 ◽  
Vol 23 ◽  
Author(s):  
Sayyed Mohammad Ali Noori ◽  
Mohammad Hashemi ◽  
Sajjad Ghasemi
Keyword(s):  
Heavy Metals ◽  
Trace Elements ◽  
Inductively Coupled Plasma ◽  
Chemical Elements ◽  
Absorption Spectrometry ◽  
Atomic Emission ◽  
Emission Spectrometry ◽  
Inductively Coupled ◽  
Wide Range ◽  
The World

Abstract: Saffron is one of the most expensive spices in the world, and its popularity as a tasty food additive is spreading rapidly through many cultures and cuisines. Minerals and heavy metals are minor components found in saffron, which play a key role in the identification of the geographical origin, quality control, and food traceability, while they also affect human health. The chemical elements in saffron are measured using various analytical methods, such as techniques based on spectrometry or spectroscopy, including atomic emission spectrometry, atomic absorption spectrometry, inductively coupled plasma optical emission spectrometry, and inductively coupled plasma mass spectrometry. The present study aimed to review the published articles about heavy metals and minerals in saffron across the world. To date, 64 chemical elements have been found in different types of saffron, which could be divided into three groups of macro-elements, trace elements, and heavy metals (trace elements with a lower gravity/greater than five times that of water and other inorganic sources). Furthermore, the chemical elements in the saffron samples of different countries have a wide range of concentrations. These differences may be affected by geographical condition such as physicochemical properties of the soil, weather and other environmental conditions like saffron cultivation and its genotype.

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