scholarly journals Hepatitis B and C Viral Infection in B-Thalassemic Children

2019 ◽  
Vol 10 (4) ◽  
pp. 3733-3737
Author(s):  
Mokhles Mahdi Abolewaikh Almayyahi ◽  
Flayyih Hassan Shnawa Al-Hameedawi
Keyword(s):  
Hepatitis C ◽  
Liver Injury ◽  
Hepatitis B ◽  
Viral Infection ◽  
Hepatitis A ◽  
Liver Enzymes ◽  
Female Ratio ◽  
Liver Functions

The main objective of this study is to show how both hepatitis B and C Viral Infection in B-Thalassemic patients occurs and a study of their liver functions. To define the occurrence of either hepatitis A or B and C viral infection across the B-Thalassemia key clients/patients in Thalassemia Center of AL-Diwanyia Maternity and Children hospital from 1st. Jan. –  1st.Nov.2017. To carry out the study, it enlisted 54 patients; 31 patients were male (57.4%) in which the male to the female ratio was 01.4:01. Results for this study revealed that 2 patients had Hepatitis B (3.7%), and 6 patients had Hepatitis C (11.1%). The Liver enzymes were significantly more in those patients having either Hepatitis B or C viral infection. According to this study, it was revealed that the occurrence of HBsAg seropositive in B-thalassemic patients was 307%, and Anti-HCV seropositive were 11.1%, and the rate is lower than reported in many countries. The occurrence of Anti-HCV seropositive is higher than that for HBsAg seropositive. Also, the probability of having liver injury was high for thalassemic patients whom were HBsAg positive & Anti-HCV positive than that of seronegative for HBsAg & Anti- HCV.

scholarly journals Changing Trends in Viral Hepatitis-Associated Hospitalizations in the American Indian/Alaska Native Population, 1995–2007

2011 ◽  
Vol 126 (6) ◽  
pp. 816-825 ◽  
Author(s):  
Kathy K. Byrd ◽  
John T. Redd ◽  
Robert C. Holman ◽  
Dana L. Haberling ◽  
James E. Cheek
Keyword(s):  
Health Care ◽  
Hepatitis C ◽  
Hepatitis B ◽  
American Indian ◽  
Viral Hepatitis ◽  
Alaska Native ◽  
Hepatitis A ◽  
Hospitalization Rate ◽  
Time Periods ◽  
Significant Change

Objective. We described the changing epidemiology of viral hepatitis among the American Indian/Alaska Native (AI/AN) population that uses Indian Health Service (IHS) health care. Methods. We used hospital discharge data from the IHS National Patient Information Reporting System to determine rates of hepatitis A-, B-, and C-associated hospitalization among AI/ANs using IHS health care from 1995–2007 and summary periods 1995–1997 and 2005–2007. Results. Hepatitis A-associated hospitalization rates among AI/AN people decreased from 4.9 per 100,000 population during 1995–1997 to 0.8 per 100,000 population during 2005–2007 (risk ratio [RR] = 0.2, 95% confidence interval [CI] 0.1, 0.2). While there was no significant change in the overall hepatitis B-associated hospitalization rate between time periods, the average annual rate in people aged 45–64 years increased by 109% (RR=2.1, 95% CI 1.4, 3.2). Between the two time periods, the hepatitis C-associated hospitalization rate rose from 13.0 to 55.0 per 100,000 population (RR=4.2, 95% CI 3.8, 4.7), an increase of 323%. The hepatitis C-associated hospitalization rate was highest among people aged 45–64 years, males, and those in the Alaska region. Conclusions. Hepatitis A has decreased to near-eradication levels among the AI/AN population using IHS health care. Hepatitis C-associated hospitalizations increased significantly; however, there was no significant change in hepatitis B-associated hospitalizations. Emphasis should be placed on continued universal childhood and adolescent hepatitis B vaccination and improved vaccination of high-risk adults. Prevention and education efforts should focus on decreasing hepatitis C risk behaviors and identifying people with hepatitis C infection so they may be referred for treatment.

scholarly journals Hepatitis viral en la gestación

1996 ◽  
Vol 47 (1) ◽  
pp. 47-50
Author(s):  
Pío Iván Gómez Sánchez
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Hepatitis A ◽  
Hepatitis E ◽  
Hepatitis Delta

La primera causa de ictericia en el embarazo es la hepatitis viral que puede ser causada por lo menos por cinco virus (A, B, C, D y E). El descubrimiento del virus de la hepatitis C y Delta prácticamente eliminó las antes denominadas Hepatitis No A No B y aún existe la posibilidad de descubrir nuevos virus.En este artículo se presenta un caso clínico de hepatitis B y se revisa etiología, diagnóstico, profilaxis y tratamiento de las diferentes hepatitis virales, haciendo énfasis en el diagnóstico, tratamiento y profilaxis del hijo de madre con hepatitis B, por la morbimortalidad que representa. Se revisa la hepatitis Delta, importante en Colombia, por tener zonas endémicas de este virus que requiere la infección previa o simultánea de hepatitis B. Por último se revisa la hepatitis E, de características similares a la hepatitis A, pero que afecta preferencialmente a la mujer gestante y en ella tiene mayor índice de morbimortalidad.

PERANCANGAN SISTEM PENDIAGNOSA PENYAKIT HEPATITIS DENGAN METODE CASE BASED REASONING (CBR)

2019 ◽  
Vol 1 (2) ◽  
Author(s):  
Darsin Darsin ◽  
Mira Febriana Sesunan
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Hepatitis A ◽  
Hepatitis E ◽  
Case Based Reasoning ◽  
Virus Hepatitis ◽  
Case Based

Penyakit Hepatitis adalah penyakit yang disebabkan oleh beberapa jenis virus yang menyerang dan menyebabkan peradangan serta merusak sel-sel organ hati manusia. Hepatitis dikategorikan dalam beberapa golongan, diantaranya hepatitis A, B, C, D dan E. Hepatitis dibagi menjadi 2 yaitu hepatitis akut yang  berlangsung kurang dari 6 bulan ditularkan melalui fecal oral lewat makanan dan hepatitis kronis yang berlangsung lebih dari 6 bulan ditularkan lewat cairan parenrral, seksual, plasenta. Hepatitis akut terdiri dari virus hepatitis A dan virus hepatitis E, sedangkan hepatitis kronis terdiri dari virus hepatitis B dan virus hepatitis C. Di Indonesia penyakit Hepatitis yang paling banyak di derita adalah hepatitis A, B dan hepatitis C. Sedangkan mengidentifikasi serangan penyakit pemyakit hepatitis, dapat dilakukan dengan cara melihat fisik secara langsung pada setiap bagian tubuh, baik kulit, mata, air seni. Dalam penelitian ini, dilakukan identifikasi penyakit hepatitis A, B, C, D, E. Sistem penalaran komputer berbasis kasus case based reasoning (CBR) merupakan sistem yang bertujuan untuk menyelesaikan suatu kasus baru dengan cara mengadaptasi solusi-solusi yang terdapat kasus-kasus sebelumnya yang mirip dengan kasus baru tersebut.

scholarly journals Biochemical Parameters in Common Viral Hepatitis

1970 ◽  
Vol 11 (1) ◽  
pp. 42-45 ◽  
Author(s):  
Md Ashraf-Uz-Zaman ◽  
Bilquis Ara Begum ◽  
Humaira Binte Asad ◽  
Shafia Sharmin Moutoshi ◽  
Md Nasiruddin
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Biochemical Parameters ◽  
Hepatitis A ◽  
Serum Alkaline Phosphatase ◽  
Hepatitis E ◽  
Mean Value ◽  
Serum Bilirubin Level ◽  
Hepatitis D

Viral hepatitis is the inflammation of the liver caused by hepatitis viruses. The most common causes of viral hepatitis are the five unrelated hepatotropic viruses Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D, and Hepatitis E. The aim of this study is to assess the biochemical parameters in viral hepatitis which varies with respect to the different types of viral hepatitis. Sex of the patient affected by Hepatitis A was almost similar in male and female, being 9 (45%) and 11 (55%) in respectively. But in contrast, more than eighty per cent (85%) Hepatitis-E affected population was male. Similar scenario was found in Hepatitis B And C infection (Male- 75%,67%, Female 25,35%). Mean value with standard deviation (±SD) of serum bilirubin level was highest in Hepatitis E (251 ± 125.19 ìmol/l). Value of serum ALT in hepatitis E was found to be 1794 U/l (highest), hepatitis B 1362 U/l hepatitis C are 135.45 U/L,. Serum aspartate aminotransferase (S.AST) is also raised in all types of vira hepatitis but more in Hepatitis E (765 U/l) and Hepatitis B (430 U/l). Serum Alkaline Phosphatase (ALP) was raised significantly in Hepatitis B (240 U/l). The prothombin time was more altered in Hepatitis-E (22.7seconds) and Hepatitis-B (18.5 seconds). There was no significant alteration in serum protein level. So, it can be concluded that derangement of biochemical parameters in patients suffering from common types of viral hepatitis is more in HEV and HBV and comparatively less in HAV and HCV. Keywords: Viral hepatitis, hepatitis A, hepatitis B, hepatitis C, hepatitis D, hepatitis E DOI:10.3329/jom.v11i1.4268 J Medicine 2010: 11: 42-45

Role of occult hepatitis B virus in chronic hepatitis C patients with flare of liver enzymes

2011 ◽  
Vol 22 (2) ◽  
pp. 187-190 ◽  
Author(s):  
Heba S. Selim ◽  
Hadia A. Abou-Donia ◽  
Hossam A. Taha ◽  
Gasser I. El Azab ◽  
Ahmed F. Bakry
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Liver Enzymes ◽  
Occult Hepatitis ◽  
B Virus ◽  
Occult Hepatitis B ◽  
Chronic Hepatitis C Patients

scholarly journals An outbreak of acute jaundice syndrome (AJS) among the Rohingya refugees in Cox’s Bazar, Bangladesh: Findings from enhanced epidemiological surveillance

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250505
Author(s):  
Md Khadimul Anam Mazhar ◽  
Flavio Finger ◽  
Egmond Samir Evers ◽  
Anna Kuehne ◽  
Melissa Ivey ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Disease Surveillance ◽  
Large Scale ◽  
Hepatitis A ◽  
Hepatitis A Virus ◽  
Hepatitis E ◽  
Case Definition ◽  
Epidemiological Surveillance ◽  
Enzyme Linked Immunosorbent Assay

In the summer of 2017, an estimated 745,000 Rohingya fled to Bangladesh in what has been described as one of the largest and fastest growing refugee crises in the world. Among numerous health concerns, an outbreak of acute jaundice syndrome (AJS) was detected by the disease surveillance system in early 2018 among the refugee population. This paper describes the investigation into the increase in AJS cases, the process and results of the investigation, which were strongly suggestive of a large outbreak due to hepatitis A virus (HAV). An enhanced serological investigation was conducted between 28 February to 26 March 2018 to determine the etiologies and risk factors associated with the outbreak. A total of 275 samples were collected from 18 health facilities reporting AJS cases. Blood samples were collected from all patients fulfilling the study specific case definition and inclusion criteria, and tested for antibody responses using enzyme-linked immunosorbent assay (ELISA). Out of the 275 samples, 206 were positive for one of the agents tested. The laboratory results confirmed multiple etiologies including 154 (56%) samples tested positive for hepatitis A, 1 (0.4%) positive for hepatitis E, 36 (13%) positive for hepatitis B, 25 (9%) positive for hepatitis C, and 14 (5%) positive for leptospirosis. Among all specimens tested 24 (9%) showed evidence of co-infections with multiple etiologies. Hepatitis A and E are commonly found in refugee camps and have similar clinical presentations. In the absence of robust testing capacity when the epidemic was identified through syndromic reporting, a particular concern was that of a hepatitis E outbreak, for which immunity tends to be limited, and which may be particularly severe among pregnant women. This report highlights the challenges of identifying causative agents in such settings and the resources required to do so. Results from the month-long enhanced investigation did not point out widespread hepatitis E virus (HEV) transmission, but instead strongly suggested a large-scale hepatitis A outbreak of milder consequences, and highlighted a number of other concomitant causes of AJS (acute hepatitis B, hepatitis C, Leptospirosis), albeit most likely at sporadic level. Results strengthen the need for further water and sanitation interventions and are a stark reminder of the risk of other epidemics transmitted through similar routes in such settings, particularly dysentery and cholera. It also highlights the need to ensure clinical management capacity for potentially chronic conditions in this vulnerable population.

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