The Link between Smoking and Covid 19 — A Short Review

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 931-933
Author(s):  
Swapnaja Gosavi ◽  
Sunita Shrivastav ◽  
Ranjit kamble ◽  
Pallavi Daigavane ◽  
Suchitra Gosavi
Keyword(s):  
Cardiovascular Disease ◽  
Chronic Obstructive Pulmonary Disease ◽  
Risk Factor ◽  
Short Review ◽  
Present Condition ◽  
Health Conditions ◽  
Chronic Obstructive ◽  
Detailed Knowledge ◽  
Obstructive Pulmonary Disease

Smoking is always said to be a risk factor in many of the health conditions. Smokers are always at a higher risk. COVID 19 is a whole new chapter of its own. Recent research has stated that in COVID-19 smokers are 14 times more prone to death. Awareness in Indians is lacking, and they do not know the effects of smoking. Literature refers to the comorbidities like smoking, cancer, cardiovascular disease, chronic obstructive pulmonary disease diabetes etc. as "pre-existing conditions”. The term coronavirus is used because of their appearance to a crown-like structure having long spikes of transmembrane glycoproteins. The link between coronavirus and smokers is still unknown. the role of angiotensin in smokers and its link-up with coronavirus needs to be understood. However, clarification regarding the casual link of these comorbidities to COVID-19 does not exist in the present literature. This article focuses on the link between smoking and COVID 19 and its effects. It provides detailed knowledge regarding the link between coronavirus and smokers, which is the need of the hour as awareness is necessary for the present condition. This article focuses on the present condition as well as the link between smokers and the coronavirus.

scholarly journals The Potential Roles of Extracellular Vesicles in Cigarette Smoke-Associated Diseases

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
A-Reum Ryu ◽  
Do Hyun Kim ◽  
Eunjoo Kim ◽  
Mi Young Lee
Keyword(s):  
Lung Cancer ◽  
Cardiovascular Disease ◽  
Chronic Obstructive Pulmonary Disease ◽  
Cigarette Smoke ◽  
Extracellular Vesicles ◽  
Chronic Obstructive ◽  
Future Prospects ◽  
Obstructive Pulmonary Disease ◽  
Diagnostic Biomarkers

Cigarette smoke contains more than 4,500 chemicals; most of which are highly reactive free radicals, which induce proinflammatory and carcinogenic reactions. Numerous efforts have focused extensively on the role of cigarette smoking as a cause of many diseases. Extracellular vesicles and exosomes have recently received increasing interest for their diagnostic and therapeutic roles in many diseases. However, research done on the role of extracellular vesicles and exosomes on cigarette smoke-induced chronic disease is still in its infancy. In this review, we summarize the recently addressed roles of extracellular vesicles and exosomes in the pathogenesis of cigarette smoke-related diseases, such as chronic obstructive pulmonary disease, cardiovascular disease, lung cancer, and oral cancer. Moreover, their potential utilization and future prospects as diagnostic biomarkers for cigarette smoke-related diseases are described.

scholarly journals Insights into Chronic Obstructive Pulmonary Disease as Critical Risk Factor for Cardiovascular Disease

2020 ◽  
Vol Volume 15 ◽  
pp. 755-764
Author(s):  
Pere Almagro ◽  
Ramon Boixeda ◽  
Jesús Diez-Manglano ◽  
María Gómez-Antúnez ◽  
Franciso López-García ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Chronic Obstructive Pulmonary Disease ◽  
Risk Factor ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease

Role of exhaled nitric oxide in predicting steroid response in chronic obstructive pulmonary disease

2010 ◽  
Vol 151 (51) ◽  
pp. 2083-2088 ◽  
Author(s):  
Balázs Antus
Keyword(s):  
Nitric Oxide ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Exhaled Nitric Oxide ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Steroid Response

A kilégzett levegőben mérhető nitrogén-monoxid a legszélesebb körben vizsgált légúti biomarker. A stabil állapotú krónikus obstruktív tüdőbetegségben a kilégzett nitrogén-monoxid-szint hasonló vagy csak kismértékben emelkedett az egészségesekhez képest. Mivel a nitrogén-monoxid-szint szoros összefüggést mutat a légúti eosinophilia mértékével, és mivel az eosinophil típusú légúti gyulladás szteroidokra érzékenyebb, az emelkedett nitrogén-monoxid-szinttel rendelkező betegek jobb válaszkészséget mutatnak az inhalációs vagy szisztémás kortikoszteroidkezelésre. A krónikus obstruktív tüdőbetegség akut exacerbatiója során a kilégzett nitrogén-monoxid szintje megemelkedik, majd ennek kezelése után csökken. Mivel a nitrogén-monoxid-szint és a kezelés során elért légzésfunkciós javulás szoros korrelációt mutat egymással, a nitrogén-monoxid-méréssel a terápiás válasz megjósolható. Összefoglalva: a nitrogén-monoxid-méréssel a krónikus obstruktív tüdőbetegségben szenvedő betegek olyan alcsoportját lehet elkülöníteni, amelynek szteroidérzékenysége nagyobb. Orv. Hetil., 2010, 151, 2083–2088.

Participation of ABCA1 transporter in development of chronic obstructive pulmonary disease

2020 ◽  
Vol 28 (3) ◽  
pp. 360-370
Author(s):  
Stanislav N. Kotlyarov ◽  
Anna A. Kotlyarova
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Significant Contribution ◽  
Modern Medicine ◽  
Lipid Homeostasis ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Reverse Transport ◽  
Current Paradigm

Despite all achievements of the modern medicine, the problem of chronic obstructive pulmonary disease (COPD) does not lose its relevance. The current paradigm suggests a key role of macrophages in inflammation in COPD. Macrophages are known to be heterogeneous in their functions. This heterogeneity is determined by their immunometabolic profile and also by peculiarities of lipid homeostasis of cells. Aim. To analyze the role of the ABCA1 transporter, a member of the ABC A subfamily, in the pathogenesis of COPD. The expression of ABCA1 in lung tissues is on the second place after the liver, which shows the important role of the carrier and of lipid homeostasis in the function of lungs. Analysis of the literature shows that participation of the transporter in inflammation consists in regulation of the content of cholesterol in the lipid rafts of the membranes, in phagocytosis and apoptosis. Conclusion. Through regulation of the process of reverse transport of cholesterol in macrophages of lungs, ABCA1 can change their inflammatory response, which makes a significant contribution to the pathogenesis of COPD.

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