Study of effect of maternal haemoglobin level on cord blood haematological profile (HB, Retic count, PCV) in newborn delivered in PIMS and R Hospital Urun Islampur, Sangli Maharashtra.

Background: While it is customary to apply the same haematological reference ranges, variations exist between populations. This study was conducted to determine hematologic profiles among a local population of north-western Tanzania.Methods: This was a cross sectional study, which enrolled healthy adult blood donors in Mwanza, Tanzania. Collected blood samples were put in EDTA-coated tubes and haematological indices were determined using Auto Hematology-Analyzer. Results are summarized in medians plus 95% interquartile ranges and compared using either Mann–Whitney U or Kruskal–Wallis tests depending on appropriateness.Results: A total of 163 (143 males and 20 females) adult healthy blood donors (median age= 31 years) were enrolled. We found a median haemoglobin level of 15.1 g/dL [10.5-23.8], erythrocytes of 5.3x106/µL [4.1-8.3 x106], haematocrit of 44.0 % [32.4-71.4], total leucocytes of 4300 cells/μL [1700-8500], lymphocytes 1700/μL [800-3000], neutrophils 2100/μL [300-5300]; mid-sized cells (monocytes, eosinophils and basophils) of 400/μL [100-1400] and platelets of 194x103/μL [55.2-379.0 x103]. We observed significantly higher haemoglobin level (P = 0.017) as well as erythrocytes (P = 0.012) and haematocrit (p = 0.006) among males than females. Conclusion: The percentile range (2.5%-97.5%) which can be used to determine the higher and lower values of haematological profile normal ranges for most indices differ from Western adopted reference values. Therefore, we recommend a large study to establish local normal hematologic reference values.

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Hematological profile including alkali resistant hemoglobin of neonates at birth using cord blood in relation to gestational age and maternal diseases

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20164535 ◽

2016 ◽

Vol 5 (1) ◽

pp. 131

Author(s):

Debashis Bhattacharya ◽

Sharmistha Chatterjee ◽

Gargi Sen

Keyword(s):

Cord Blood ◽

Cell Count ◽

Gestational Age ◽

White Cell Count ◽

Tertiary Care ◽

Cord Blood Sample ◽

Care Hospital ◽

Cross Sectional ◽

Hematological Profile ◽

Haematological Profile

Background: The importance of complete hemogram along with the hematological indices in the diagnosis of neonatal health cannot be overemphasized. There is a severe paucity of relevant data regarding neonatal hematological profile in relation to gestational age and maternal diseases in this part of the country. With this perspective, the authors intended to do a pilot study to analyse the haematological profile of neonates of different gestational ages and different maternal diseases born in a teriary care hospital in Eastern India.Methods: This is a cross sectional study design based on cord blood sample of newborns and their mothers recruited from those admitted in the gynae and obstetric department in IPGME&R. The umbilical cord blood was collected from the newborn babies and then examined for different haematological parameters. The data obtained was statistically analysed.Results: While there has been a sequential rise of fetal red cell count, hemoglobin and the total white cell count neutrophils with gestational age, the mean corpuscular cell volume decreased. All these values were comprised to varying degrees in maternal diseases except for nucleated rell blood cells which conspicuously increased in neonates of diabetic mothers.Conclusions: In this study, a small attempt was made to assess the haematological profile (including alkali resistant hemoglobin) of the newborns in relation to gestational age and maternal diseases in the population attending a tertiary care hospital in Eastern India.

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