scholarly journals The Effect of Pepper Nigrum, Olea Europaea Mouthwash with Non Surgical Periodontal Therapy on Clinical Outcome And Oxidative Stress in Chronic Periodontitis Patients

2021 ◽  
Vol 24 (2) ◽  
pp. 103-113
Author(s):  
Suzan Taha ◽  
◽  
Najla Issa ◽  
Saeed Mohammed ◽  
◽  
...  
2019 ◽  
Vol 8 (4) ◽  
pp. 148 ◽  
Author(s):  
Maryam Moghimian ◽  
Hamed Shoorei ◽  
Majid Shokoohi ◽  
Malihe Soltani ◽  
Seyed-Hosein Abtahi-Eivary ◽  
...  

2012 ◽  
Vol 32 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Swati Pradeep Patel ◽  
Nishanth S. Rao ◽  
A. R. Pradeep

Background: Plasma glutathione peroxidase (eGPx) is an important selenium containing antioxidant in human defense against oxidative stress. While crevicular fluid (GCF) eGPx levels and its association with periodontal disease is well documented, there is no data on correlation of GCF and serum eGPx levels in chronic periodontitis. Hence this study was undertaken to further probe into the role of oxidative stress in periodontal diseases and effect of nonsurgical periodontal therapy (NSPT) by correlating GCF and serum levels of eGPx.Materials and methods: Thirty subjects (16-Males and 14-Females; age: 30–38 years) participated in the study. The subjects were divided, based on gingival index, probing pocket depth and clinical attachment level into: Healthy (group-1,n=10), Gingivitis (group-2,n=10) and Periodontitis (group-3,n=10). Chronic periodontitis patients after NSPT constituted group 4. GCF and serum samples collected from each subject were quantified for eGPx levels using Enzyme linked Immunosorbent Assay.Results: The mean eGPx concentrations increased from health (14.01 ng/μl and 78.26 ng/ml) to gingivitis (22.86 ng/μl and 90.44 ng/ml) and then to periodontitis (29.89 ng/μl and 103.43 ng/ml), in GCF and serum respectively. After NSPT, there was statistically significant reduction in eGPx concentration in GCF and serum (19.41 ng/μl and 85.21 ng/ml). Further, all the GCF eGPx values showed a positive correlation to that of serum eGPx level.Conclusion: Thus, increased eGPx concentration in GCF can be considered as an indicator of local increase in oxidative stress. While, increase in serum eGPx levels indicates that periodontal disease can also lead to increased oxidative stress at the systemic level.


2014 ◽  
Vol 3 (2) ◽  
pp. 153 ◽  
Author(s):  
Oguz Kose ◽  
Varol Canakci ◽  
Cenk Canakci ◽  
Abdulkadir Yildirim ◽  
Eda Kermen ◽  
...  

2019 ◽  
Vol 10 ◽  
Author(s):  
Alberto Marco Del Pino ◽  
Luca Regni ◽  
Roberto D’Amato ◽  
Emma Tedeschini ◽  
Daniela Businelli ◽  
...  

2019 ◽  
Vol 111 ◽  
pp. 676-685 ◽  
Author(s):  
Haifa A.S. ALHaithloul ◽  
Mohammed F. Alotaibi ◽  
May Bin-Jumah ◽  
Hassan Elgebaly ◽  
Ayman M. Mahmoud

Antioxidants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 226
Author(s):  
Maria-Alexandra Martu ◽  
Petra Surlin ◽  
Luminita Lazar ◽  
George Alexandru Maftei ◽  
Ionut Luchian ◽  
...  

(1) Background: The aim of this split-mouth design study was to analyze the clinical periodontal indexes and oxidative stress markers in gingival crevicular fluid modifications after three periodontal disease treatment possibilities (scaling and root planning—SRP; SRP and diode laser—L; SRP and photodynamic therapy—PDT). (2) Methods: The study was conducted on 52 patients: systemically healthy subjects with periodontal disease—non-RA (n = 26); and test group (n = 26) subjects with rheumatoid arthritis and periodontal disease—RA. Clinical periodontal measurements (probing depth—PD; Löe and Silness gingival index—GI; papillary bleeding index—PBI; and periodontal community index of treatment needs—CPITN) and oxidative stress markers (8-hydroxy-2’-deoxyguanosine (8-OHdG) and 4 hydroxynonenal (4-HNE)) were analyzed at baseline (T0), after three sessions of periodontal treatment (T1), and 6 months after treatment (T2). (3) Results: Periodontal therapy improved clinical periodontal measurements and oxidative stress markers in both analyzed groups, with supplementary benefits for laser- and PDT-treated periodontal pockets. (4) Conclusions: The analyzed oxidative stress markers decreased significantly following non-surgical periodontal therapy in both rheumatoid arthritis and systemically healthy patients. All the periodontal disease treatment possibilities analyzed in this study offered clinical and paraclinical improvements; however, the association of laser with SRP and photodisinfection with SRP yielded the best clinical and paraclinical outcomes when compared to SRP alone.


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