scholarly journals Anesthetic Effect of Sufentanil Combined with Remifentanil in Patients Undergoing Radical Gastrectomy

2021 ◽  
Vol 5 (4) ◽  
pp. 225-228
Author(s):  
Jianyue Wang
Keyword(s):  
Gastric Cancer ◽  
Postoperative Pain ◽  
Control Group ◽  
Study Group ◽  
Radical Gastrectomy ◽  
Research Subjects ◽  
Clinical Value ◽  
Anesthetic Effect ◽  
Before And After ◽  
Better Than

Objective: To explore and analyze the anesthetic effect of sufentanil combined with remifentanil in patients undergoing radical gastrectomy for gastric cancer. Methods: In this study, 100 patients receiving radical gastrectomy for gastric cancer in our hospital were selected as the research subjects, and the period from June 2019 to February 2021 was divided into different anesthesia regimens. Fifty patients receiving remifentanil anesthesia were used as the control group, and 50 patients receiving remifentanil combined with sufentanil anesthesia were used as the research group. The anesthetic effect of the two groups of patients was analyzed and compared. Results: The HR and MAP of the study group at different time after intubation were lower than those of the control group (P<0.05). The changes of HR and MAP before and after intubation in two groups were significant compared with those before intubation (P<0.05). The postoperative VAS score of the study group was significantly better than that of the control group (P<0.05). Conclusions: In radical gastrectomy for gastric cancer, the choice of sufentanil and remifentanil as the anesthesia scheme can effectively stabilize the hemodynamics of patients, relieve the degree of postoperative pain, with obvious clinical value.

scholarly journals Anesthetic Effect of Compound Artevacaine Hydrochloride in Patients Undergoing Oral Implantation

2021 ◽  
Vol 5 (4) ◽  
pp. 220-224
Author(s):  
Chengxi Chi ◽  
Mengmeng Zhao ◽  
Jiajing He ◽  
Yanli Wang
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Operation Time ◽  
Control Group ◽  
Study Group ◽  
Research Subjects ◽  
Implant Surgery ◽  
Anesthetic Effect ◽  
Significant Difference ◽  
Oral Implant

Objective: To investigate and analyze the anesthetic effect of compound artevacaine hydrochloride in patients undergoing oral implantation. Methods: In this study, 60 patients receiving oral implant surgery in our hospital were selected as the research subjects, and the operation time was from July 2019 to March 2021. Patients were randomly selected and divided into groups for the study. 30 patients receiving lidocaine hydrochloride anesthesia were used as the control group, and 30 patients receiving compound artevacaine hydrochloride anesthesia were used as the research group. The anesthetic effect and safety of the two groups were compared and analyzed. Results: The anesthetic effect of the study group was significantly better than that of the control group (P < 0.05). The blood pressure and heart rate in the study group were significantly lower than those in the control group (P < 0.05). There was no significant difference in blood pressure and heart rate between the two groups before anesthesia (P > 0.05). There was no significant difference in the incidence of ADR between the two groups (P > 0.05). Conclusions: For patients undergoing oral implant surgery, choosing compound artevacaine hydrochloride as anesthetic drug has obvious anesthetic effect and can stabilize patients' life indexes. The anesthetic effect is obvious, and there is no obvious adverse reaction, and the clinical value is obvious.

Effect of psychological nursing combined with medication on postoperative pain in patients with mixed hemorrhoids

2021 ◽  
Vol 7 (6) ◽  
pp. 6437-6444
Author(s):  
Jing Chen ◽  
Xiuna Qu ◽  
Huimin Wang ◽  
Xiaoyan Zhou
Keyword(s):  
Patient Satisfaction ◽  
Postoperative Pain ◽  
Pain Score ◽  
Pain Control ◽  
Control Group ◽  
Observation Group ◽  
Research Subjects ◽  
Anal Eczema ◽  
Perianal Eczema ◽  
Better Than

The study analyzes the practical effect of applying psychological nursing combined with medication to relieve pain in patients with mixed sore after surgery. A total of 60 patients with mixed sores treated in our hospital from April 2017 to April 2018 were selected as research subjects. All patients were divided into observers and control groups using random number methods. The control group was treated with routine nursing and in the treatment group, the observation group was treated with psychological nursing combined with medication, and the postoperative pain scores, patient satisfaction with pain control, post-anal eczema, and psycho-emotional score were compared between the two groups. In the pain score of 24 hours after surgery and the defecation pain score of 5 days after surgery, the observation group was significantly lower than the control group (P <0.05). In terms of patient satisfaction with pain control, the observation group was significantly better than the control group (P <0.05).), The perianal eczema in the observation group was significantly lower than that in the control group (P <0.05); the psychological and emotional score of the observation group was significantly better than that in the control group (P <0.05), and the differences were statistically significant. For patients with mixed sores, the application of psychological nursing combined with drug treatment has significant effects, significantly reducing the pain of defecation after 24 hours and 5 days after surgery. Patients are more satisfied with pain control, which is worthy of promotion and application in clinical treatment and nursing.

scholarly journals Study on the Regulation of Qinxitong Combined with Methotrexate Tablets on Multiple Inflammatory Indicators and Mechanism Factors in Rheumatoid Arthritis

2021 ◽  
Vol 5 (6) ◽  
pp. 113-117
Author(s):  
Zhaoyang Dong ◽  
Jichao Yin
Keyword(s):  
Rheumatoid Arthritis ◽  
Control Group ◽  
Study Group ◽  
Observation Group ◽  
Regulatory Effect ◽  
Inflammatory Index ◽  
Normal People ◽  
Before And After ◽  
And Control ◽  
Better Than

Objective: To study the changes of several inflammatory index mechanism factors in the clinical efficacy of tablet and methotrexate in rheumatoid arthritis. Methods: 20 patients with rheumatoid arthritis were randomly divided into observation (n =10) and control (n =10), then normal people as normal (n=10), all three groups were given methotrexate and the observation group were treated with Qin interest pain tablets. Expression of inflammatory index mechanism factors in each group. Results: After treatment, inflammatory index mechanism factors were detected; a significant decrease of IFN-g, IL-1b, IL-10, IL-37, TNF-a and other factors was found before and after combination treatment (P <0); IL-8 and IL-13 expression (P <0); the CRP, ESR score of the study group was lower than the control group (P <0.05); and the inflammatory index mechanism factors were affected by drug combination. Conclusion: Tablets combined with methotrexate in rheumatoid arthritis patients is better than methotrexate. It obviously changed the expression of the patient’s inflammatory index mechanistic factors, which has a regulatory effect on the inflammatory mechanistic factors.

scholarly journals Short-Term Efficacy and Quality of Life of Gastric Cancer Patients Undergoing Radical Gastrectomy Assisted by External Vision

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Jian Zheng ◽  
Yingwei Xue ◽  
Chunfeng Li
Keyword(s):  
Quality Of Life ◽  
Gastric Cancer ◽  
Cancer Patients ◽  
Control Group ◽  
Observation Group ◽  
Radical Gastrectomy ◽  
The Difference ◽  
Gastric Cancer Patients ◽  
Better Than

Objective. To evaluate the clinical effects and survival prognosis of radical gastrectomy assisted by external vision in gastric cancer. Methods. A total of 60 hospitalized gastric cancer patients from June 2016 to December 2018 were selected and divided into the observation group and control group according to different surgical procedures. The control group was treated with traditional open radical gastrectomy, while the observation group was treated with radical gastrectomy assisted by an external vision microscope. Relevant surgical indicators, visual analogue scale (VAS), postoperative complications, and life quality assessment were analyzed and compared between the two groups. Results. The incision length and intraoperative blood loss in the observation group were smaller than those in the control group, and the difference was statistically significant ( P < 0.05 ); compared with the control group, the observation group had significantly shorter hospital stay, earlier postoperative first exhaust time, and lower gastric fluid volume at the 3rd day after surgery ( P < 0.05 ). The pain scores of the observation group at 1, 4, and 12 weeks after surgery were lower than those of the control group ( P < 0.05 ), and the difference was significant. The quality of life scores at the 1st week and 12th week after surgery showed that the dysphagia symptom scores of the observation group and the control group were significantly reduced but the two groups had significant differences in fatigue, physical function, pain score, postoperative pain, and overall quality of life. The observation group was significantly better than the control group ( P < 0.05 ). Follow-up studies showed no significant difference between mortality and cancer recurrence ( P > 0.05 ); the patients recovered well at postoperation, and the diet of the observation group was better than that of the control group ( P < 0.05 ); gastric reflux and knife pain were less than those of the control group ( P < 0.05 ). Conclusion. Radical gastrectomy assisted by external vision for gastric cancer yields clinical benefits for gastric cancer patients, which not only dramatically shortened the length of hospital stay but also effectively ameliorated the quality of life of patients, all indicating that external vision-assisted surgery was significantly better than traditional gastrectomy in improving the postoperative quality of life of gastric cancer patients in the absence of increasing the risk of adverse events.

Effect of Bundle Management in the Reduction of EN Complications in Patients Receiving Enteral Nutrition (EN) in the ICU

2021 ◽  
Vol 7 (5) ◽  
pp. 3063-3067
Author(s):  
Jiaoping Zhang ◽  
Pei Zhang
Keyword(s):  
Enteral Nutrition ◽  
Random Number ◽  
Family Members ◽  
Control Group ◽  
Study Group ◽  
Clinical Value ◽  
Nursing Outcomes ◽  
Management Measures ◽  
Significant Difference ◽  
Better Than

To investigate the efficacy of bundle management in reducing EN complications in ICU enteral nutrition (EN) patients. Methods: In this study, 90 patients with enteral nutrition who were admitted to our hospital and ICU from January 2018 to January 2021 were randomly divided into two groups by random number method: control group (n = 45) treated with routine nursing management and study group (n = 45) treated with bundle management by random number method. The nursing outcomes of the two groups were compared. Results: The incidence rate of enteral nutrition complications in the study group was significantly lower than that in the control group (P<0.05). The nutritional indexes after intervention in the study group were significantly better than those in the control group (P<0.05). There was no significant difference in the relative ratio of nutritional indexes before intervention between the two groups (P>0.05). The satisfaction degree of the patients’ family members in the study group was significantly better than that of the patients’ family members in the control group (P<0.05). Conclusion: Bundle management measures for patients with enteral nutrition in ICU can effectively improve the nutritional index of patients and the satisfaction of their family members, and reduce the incidence of complications of enteral nutrition, which has obvious clinical value.

Effect of Bundle Management in the Reduction of EN Complications in Patients Receiving Enteral Nutrition (EN) in the ICU

2021 ◽  
Vol 7 (4) ◽  
pp. 417-421
Author(s):  
Jiaoping Zhang ◽  
Pei Zhang
Keyword(s):  
Enteral Nutrition ◽  
Random Number ◽  
Family Members ◽  
Control Group ◽  
Study Group ◽  
Clinical Value ◽  
Nursing Outcomes ◽  
Management Measures ◽  
Significant Difference ◽  
Better Than

To investigate the efficacy of bundle management in reducing EN complications in ICU enteral nutrition (EN) patients. Methods: In this study, 90 patients with enteral nutrition who were admitted to our hospital and ICU from January 2018 to January 2021 were randomly divided into two groups by random number method: control group (n = 45) treated with routine nursing management and study group (n = 45) treated with bundle management by random number method. The nursing outcomes of the two groups were compared. Results: The incidence rate of enteral nutrition complications in the study group was significantly lower than that in the control group (P<0.05). The nutritional indexes after intervention in the study group were significantly better than those in the control group (P<0.05). There was no significant difference in the relative ratio of nutritional indexes before intervention between the two groups (P>0.05). The satisfaction degree of the patients' family members in the study group was significantly better than that of the patients' family members in the control group (P<0.05). Conclusion: Bundle management measures for patients with enteral nutrition in ICU can effectively improve the nutritional index of patients and the satisfaction of their family members, and reduce the incidence of complications of enteral nutrition, which has obvious clinical value.

A STUDY ON THE VARIATION IN CA 72-4 LEVELS OF THE GASTRIC CANCER’S PATIENTS BEFORE AND AFTER SURGERY TREATMENT

2011 ◽  
pp. 81-87
Author(s):  
Thi Thu Huong Hoang ◽  
Minh Vuong Nguyen
Keyword(s):  
Gastric Cancer ◽  
Study Groups ◽  
University Hospital ◽  
Control Group ◽  
Central Hospital ◽  
Before And After

Objectives: Studying on the variation in CA 72-4 levels of the gastric cancer’s patients before and after 10 days and 30 days surgery treatment. Materials and methods: The studying group included 42 gastric cancer’s patients who were examinated and treated in cancerology service of Hue University Hospital and gastroenterology service of Hue Central Hospital. The control group included 30 healthy normal examinated at Hue University Hospital. The study groups were clinical, endoscopic anatopathologic examination diagnosed with gastric cancer and quantitative levels of CA 72-4 in three times points: before surgerying, after surgerying 10 days and 30 days postoperatively. Rerults: The concentration of CA 72-4 in gastric cancer’s patients was 10.06 ± 16.49 U/ml. Clearly higher than the control group 1.2 ± 0.4 U/ml(p <0.01). The rate increased levels of CA 72-4 in gastric cancer’s patients before surgerying was 27.5% and the control group was 0%. After 10 days of surgery, CA 72-4 level was 5.56 ± 8.55 U/ml; 82.5% of patients have reduced levels of CA 72-4 and 17.5% no changes; there are 0% increased cases. After 30 days of surgery, CA 72-4 level was 3.79 ± 6,52 U/ml. CA 72-4 level 10 days after surgering have decreased significantly compared to before surgery (p < 0.05) and 30 days after surgery have decreased significantly compared to after 10 days (p < 0.05). 30 days postoperatively, 90% patients had reduced levels of CA 72-4, 10% no changes, no patient had increased levels of CA 72-4 and no patient be relapsed after 30 days of treatment. Conclusions: CA 72-4 concentrations before surgerying increased 27.5%, after surgery 10 days and 30 days reduced step by step, no case have increased CA 72-4 levels, no case relapsed after 30 days.

Comparison of Analgesic Effect of Levobupivacaine with Dexmedetomidine and Levobupivacaine for Scalp Block before Supratentorial Craniotomy: A Randomized Controlled Trial

2020 ◽  
Vol 103 (10) ◽  
pp. 1028-1035
Keyword(s):  
Postoperative Pain ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Control Group ◽  
Study Group ◽  
Analgesic Requirement ◽  
Supratentorial Craniotomy ◽  
Numerical Rating ◽  
Fentanyl Consumption ◽  
Scalp Block

Background: Craniotomy causes acute and chronic pain. Uncontrolled postoperative pain may lead to adverse events. Perioperative scalp nerves block is not only effective in reducing intraoperative hemodynamic response, but it also reduces postoperative pain and postoperative analgesia requirement. Objective: To compare the benefits of adding dexmedetomidine to levobupivacaine in scalp nerves block before craniotomy for the duration of analgesia in supratentorial craniotomy. Materials and Methods: After approval by the Committee for Research, 50 supratentorial craniotomy patients were randomized into two groups. The control group received 30 mL scalp nerves block with 0.25% levobupivacaine with adrenaline 1:200,000, whereas the study group received 30 mL scalp nerves block with 0.25% levobupivacaine with adrenaline 1:200,000 plus dexmedetomidine 1 mcg/kg. The primary outcome was the time to first analgesic requirement postoperatively. The secondary outcomes included intraoperative fentanyl consumption, verbal numerical rating scale, tramadol consumption, and complications during the first 24 hours postoperatively. Results: Patients in the study group had significantly increase time to the first analgesic requirement in postoperative period and reduced intraoperative fentanyl consumption. The median time to first analgesic requirement was 555 (360 to 1,035) minutes in the study group versus 405 (300 to 520) minutes in the control group (p=0.023). Intraoperative fentanyl consumption 125 (75 to 175) mcg in the study group was significantly lower than 200 (150 to 250) mcg in the control group (p=0.02). The verbal numerical rating scale at 1, 4, 8, 12 and 24 hours postoperatively, tramadol consumption, and complications during the first 24 hours postoperatively were not statistically significant different. Conclusion: Preoperative scalp nerves block with 0.25% levobupivacaine with adrenaline (1:200,000) with dexmedetomidine 1 mcg/kg significantly increased the time to first analgesic requirement and reduced intraoperative fentanyl consumption compared to 0.25% levobupivacaine with adrenaline (1:200,000) without perioperative complications. Keywords: Scalp block, Dexmedetomidine, Post-craniotomy analgesia, Supratentorial tumor, Levobupivacaine

Effect of Pre-admission "Quasi-collective" Education on Health Education for Patients With Ophthalmic Day Surgery

2021 ◽  
Author(s):  
Li-Hua Zhang ◽  
Rong-Yan Yu ◽  
Ya-Fen Ying, ◽  
Jing Yin ◽  
Na Li ◽  
...  
Keyword(s):  
Health Education ◽  
Postoperative Care ◽  
Day Surgery ◽  
Control Group ◽  
Observation Group ◽  
Research Subjects ◽  
Better Than ◽  
Preoperative Medication

Objective: The present study aimed to explore the effect of pre-admission “quasi-collective” health education for patients with ophthalmic day surgery. Methods: For this study, a total of 200 patients undergoing ophthalmic day surgery from February 2019 to December 2019 were enrolled as the research subjects. The patients were divided randomly into the observation group and the control group, with 100 cases in each group. For the control group, conventional health education was conducted after admission. On the day of admission, the admission education and peri-operative health education were performed. For the observation group, pre-admission health education was provided to the patients, and detailed education on the admission instructions, pre-operative precautions, and simulation of the intra-operative process were given by the nurses. On the day of admission, the understanding of the education was evaluated, and any weaknesses in the health education were addressed. The anxiety status, method of handwashing, method of administering the drug to the eye, preoperative preparations, intra-operative training, preoperative medication, diet guidance, and postoperative care were compared between the two groups of patients. Results: Before discharge, there were significant differences in the anxiety scores, impact, and satisfaction of health education between the two groups of patients, all of which were statistically significant (P < 0.05). Conclusion: The pre-admission "quasi-collective" health education for patients undergoing day surgery in ophthalmology was better than conventional health education.

The effects of breathing exercises on respiratory functions, functional capacity and quality of life in vehicle spray painters

2021 ◽  
Vol 28 (12) ◽  
pp. 1-8
Author(s):  
Burak Yilmaz ◽  
Cagtay Maden ◽  
Begümhan Turhan
Keyword(s):  
Quality Of Life ◽  
Functional Capacity ◽  
Control Group ◽  
Study Group ◽  
Breathing Exercises ◽  
Sf 36 ◽  
Significant Difference ◽  
Before And After ◽  
Respiratory Exercises

Background/aims Workers engaged in vehicle spray painting are at a risk of developing respiratory problems because of the solvents in the spray paints. Changes in respiratory functions and functional capacities caused by spray painting can be improved with respiratory exercises. The aim of this study was to examine the effects of respiratory exercises on the respiratory functions, functional capacity and quality of life in vehicle spray painters. Methods A total of 70 volunteers with similar characteristics participated in the study. The groups were divided into two groups randomly (35 study group, 35 control group). Respiratory functions (value of forced expiratory volume percentage in 1 second [FEV1]), forced vital capacity percentage [FVC], FEV1/FVC percentage, peak expiratory flow percentage [PEF (%)] and maximum voluntary ventilation percentage [MVV (%)]), functional capacity (6-Minute Walk Test) and quality of life (Short Form Health Survey [SF-36]) were evaluated. The study group undertook supervised breathing exercises 3 days a week for 6 weeks. The same exercises were given to the control group as a home programme. Home programmes were followed up by telephone calls. Evaluations were performed again after 6 weeks. Results In the study group, FEV1 (%) increased more than in the control group (P<0.05). The increase in PEF (%) was similar in both groups (P>0.05). In the study group, FEV1/FVC (%) and MVV (%) were significantly different before and after the intervention (P<0.05), but there was no difference in the control group (P>0.05). There was a greater increase in the study group than in the control group (P<0.05). 6-Minute Walk Test distance (m) before and after the intervention in both groups were similar (P>0.05). Before and after the intervention, a significant difference was found in the vitality and the social function domains of the SF-36 in the study group. In the comparisons of groups, a significant difference was found in the study group in the role-emotional, social function and bodily pain domains of the SF-36 after the intervention (P<0.05). Conclusions Breathing exercises can be recommended for vehicle spray painters to avoid an increase in respiratory resistance and to improve their quality of life.

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