scholarly journals Clinical Study of Xingnaojing Injection Combined with Craniocerebral Hypothermia Apparatus in the Treatment of Acute Hemorrhagic Stroke

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Xianfang Yue ◽  
Hua Zhou
Keyword(s):  
Clinical Efficacy ◽  
Daily Living ◽  
Hemorrhagic Stroke ◽  
Effective Rate ◽  
Control Group ◽  
Activity Of Daily Living ◽  
Observation Group ◽  
Nihss Score ◽  
Xingnaojing Injection ◽  
Acute Hemorrhagic Stroke

Objective: To investigate the clinical effect of Xingnaojing injection combined with craniocerebral hypothermia apparatus in the treatment of acute hemorrhagic stroke. Methods: Seventy-two patients with acute hemorrhagic stroke admitted to our hospital from March 2018 to September 2019 were randomly divided into two groups, with 36 cases in each group. The control group (n=36) was treated with craniocerebral hypothermia apparatus, and the observation group (n=36) was treated with Xingnaojing injection combined with craniocerebral hypothermia apparatus. The clinical efficacy, the National Institutes of Health Stroke Scale (NIHSS) score and the activity of daily living (MBI score) after 1 month of treatment were compared. Results: The effective rate of treatment in the observation group was higher than that in the control group (P < 0.05); NIHSS score was decreased in both groups (P < 0.05); MBI score was increased in both groups, and the change range of the observation group was greater than that of the control group, showing statistically significant differences (P < 0.05). Conclusion: Xingnaojing injection combined with craniocerebral hypothermia apparatus can improve the clinical efficacy, the neurological impairment and activity of daily living in the treatment of acute hemorrhagic stroke, which is worthy of clinical application.

scholarly journals Study on the clinical efficacy and mechanism of octreotide combined with thrombin in patients with liver

1970 ◽  
Vol 1 (1) ◽  
Author(s):  
Zhang Xiuqin
Keyword(s):  
Liver Cirrhosis ◽  
Liver Function ◽  
Clinical Efficacy ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Before And After ◽  
Octreotide Treatment ◽  
The Difference ◽  
Treatment Observation

Objective: To observe the clinical efficacy of octreotide and thrombin in the treatment of patients with liver cirrhosis, and to explore the mechanism of octreotide and thrombin. Methods: 53 patients with cirrhosis were randomly divided into control group and observation group from January 2014 to January 2016. The control group of 26 patients, given octreotide treatment. Observation group of 27 cases, given octreotide and thrombin combination therapy. Comparison of two groups of patients with clinical efficacy and changes in liver function before and after treatment. Results: The effective rate (88.89%) in the observation group was significantly higher than that in the control group (65.38%), the difference was statistically significant (p < 0.05). Before treatment, the difference of liver function between the two groups was not statistically significant (p > 0.05). After treatment, the liver function indexes of the two groups were improved, and the observation group was superior to the control group, the difference was statistically significant (p < 0.05).

scholarly journals The Efficacy of Tripterygium Glycosides Combined with LMWH in Treatment of HSPN in Children

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Yan Jin ◽  
Yanzheng Wang ◽  
Sai Wang ◽  
Qiongqiong Zhao ◽  
Donghua Zhang ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Clinical Symptoms ◽  
Effective Rate ◽  
Control Group ◽  
Clinical Effects ◽  
Observation Group ◽  
Significant Difference ◽  
Before And After ◽  
Qilu Hospital ◽  
Tripterygium Glycosides

Objective. This study aimed to explore the clinical efficacy and relevant mechanism of Tripterygium glycosides combined with low molecular weight heparin calcium (LMWH) in the treatment of Henoch–Schönlein purpura nephritis (HSPN) in children. Methods. 64 cases of children patients with HSPN treated at Qilu Hospital (Qingdao) from January 2015 to May 2020 were selected and randomly divided into the control group and the observation group and 32 cases in each group. Conventional medical treatment was applied in the two groups, besides which the control group was given LMWH while the observation group was given Tripterygium glycosides based on the control group. The clinical efficacy and the indexes of clinical symptoms of the two groups were compared. Immune globulin level, fibrinogen content (FIB), prothrombin time (PT), platelet level (PLT), and activated partial thromboplastin time (APTT) level of the two groups were compared before and after the treatment. Results. The total effective rate in the observation group was significantly higher than that of the control group, and the recurrence rate in the observation group was lower than that in the control group. After treatment, urine red blood cell count and 24 h urine protein were obviously better than those of the control group. There was no statistically significant difference in PT between the two groups of children before and after treatment. The levels of PLT and FIB in the two groups of patients after treatment were significantly lower than before treatment, and the PLT levels in the observation group were lower than those in the control group. Conclusion. The combination of Tripterygium glycosides and LMWH had good clinical effects in the treatment of children with HSPN, and it could improve the clinical symptoms, the mechanism of which might be related to the increase of PT, a decrease of PLT, and the improvement of coagulation function.

scholarly journals Clinical Study of Acupotomy Trinity Lysis Combined with Rehabilitation Training for Spastic Paralysis after Stroke

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Fajin Wang ◽  
Jianyong Gao ◽  
Lifeng Ma ◽  
Yali Hu ◽  
Yumin Yan ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Barthel Index ◽  
Training Group ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Spastic Paralysis ◽  
Rehabilitation Training ◽  
Post Stroke ◽  
The Difference

Objective: To study the clinical efficacy of acupotomy trinity lysis combined with rehabilitation training in the treatment of spastic paralysis after stroke, and to provide guidance for clinical diagnosis and treatment. Methods: From July 2019 to November 2020, 119 patients with post-stroke spastic paralysis who were admitted to our hospital's encephalopathy department were selected as the research objects, and 61 patients were divided into acupuncture combined with rehabilitation training group as the observation group by random number table method. 58 patients were divided into the rehabilitation training group as the control group. After 21 days of treatment, they passed the modified Ashworth Spasm Scale (MAS) grading scale score, Clinical Spasm Index (clinical spasm index, CSI) assessment, Fugl-Meyer exercise function scale (FMA) ) Score, Modified Barthel Index Score, and compare the clinical efficacy after treatment. Results: After treatment, the total effective rate of the observation group (95.08%) was higher than that of the control group (86.21%), and the difference was statistically significant (P?0.05); Before treatment, the contrast difference of MAS, FMA, CSI scores and modified Barthel index scores of the two groups of patients is not statistically significant; After treatment, the MAS scores and CSI scores of the elbow and knee joints of the observation group [(1.52±0.81)(1.46±0.83)(5.87±2.12)] were significantly lower than those of the control group [(2.17±0.68) (2.03±0.79)( 8.36±2.41)]; FMA upper limb and lower limb scores and modified Barthel index [(51.87±4.41)(30.21±5.05)(72.41±5.81)] of the observation group were significantly higher than those of the control group [(44.26±4.78)(28.45) ±4.23) (68.65±6.09)], the difference was statistically significant (P<0.05). Conclusion: Acupotomy trinity lysis combined with rehabilitation training is effective in treating patients with post-stroke spastic paralysis. It provides a safe, reliable and clinically effective new program, which is worthy of popularization and application.

scholarly journals The Clinical Efficacy of Chemotherapy Combined with Traditional Chinese Medicine in the Treatment of Cervical Cancer and Its Influence on Cellular Immunity, Serum CEA, and TNF-α

2022 ◽  
Vol 2022 ◽  
pp. 1-7
Author(s):  
Qiannan Zhao ◽  
Juanjuan Liu ◽  
Sai Wang ◽  
Xiuqin Wang ◽  
Xiufang Jiang
Keyword(s):  
Cervical Cancer ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Clinical Efficacy ◽  
Treatment Method ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Sugar Chain ◽  
Tnf Α

Background. This study aims to investigate the clinical efficacy of chemotherapy combined with traditional Chinese medicine in patients with cervical cancer and its effect on cellular immunoglobulin, serum sugar chain antigen 125 (CA125), carcinoembryonic antigen (CEA), and tumor necrosis factor-α (TNF-α). Methods. Conventional chemotherapy was performed in control and observation groups. Meantime, the observation group received traditional Chinese medicine. Finally, the clinical efficacy, immunoglobulin, serum tumor markers, and serum TNF-α of the two groups were compared. Results. Compared with the control group, total effective rate in the observation group was increased. After treatment, serum CD8+, TNF-α, CA125, and CEA levels were reduced in the two groups, and the observation group was higher. In the two groups, CD3+ and CD4+ levels were enhanced after treatment, and the observation group was also higher. Compared with the control group, the immunoglobulin IgG, IgA, and IgM levels increased in the observation group. The incidence of adverse reactions in the observation group was reduced compared to the control group. Conclusion. Chemotherapy combined with traditional Chinese can help improve the clinical efficacy and immunity in patients with cervical cancer. Moreover, the safety and feasibility of the treatment method are relatively high.

scholarly journals Clinical Effect and Effective Rate of Laparoscopic Cholecystectomy for Gallstones Complicated with Gallbladder Polyps

2021 ◽  
Vol 271 ◽  
pp. 03046
Author(s):  
Xiaoming Deng ◽  
Jinjun Jiang
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Clinical Efficacy ◽  
Complication Rate ◽  
Open Cholecystectomy ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Clinical Indicators ◽  
Gallbladder Polyps ◽  
Operation Duration

This paperA total of 62 patients with gallstones and gallbladder polyps were selected from May 2019 to May 2020, who were divided into the observation group (n=31, laparoscopic cholecystectomy) and the control group (n=31, open cholecystectomy) in a 1:1 ratio. The clinical indicators, clinical efficacy, level of pain and complication rate of the two groups were recorded and compared. Results Indicators such as the operation duration (38.64±14.42min), blood loss (30.42±8.21ml), length of stay (4.71±1.82 d), first anal exhaust (21.82±6.65min), drainage volume (72.02±4.21ml), length of incision and the time for the recovery of gastrointestinal functions in the observation group were better than the control group (P<0.05). The clinical efficacy of the observation group (96.77%) was higher than that of the control group (80.65%), with statistical value =4.0260 (P<0.05). The level of pain of the observation group was lower than that of control group (P<0.05), while the complication rate in the observation group (3.22%) was also lower than that of the control group (22.58%) (P<0.05). Laparoscopic cholecystectomy is an effective treatment of gallstones complicated with gallbladder polyps, which can alleviate pain and improve the prognosis, and is thus worthy of promotion.

scholarly journals Butyphthalide in the treatment of massive Cerebral Infarction

2019 ◽  
Vol 35 (1) ◽  
Author(s):  
Xinmin Wang ◽  
Yingjun Sun ◽  
Shugang Dong ◽  
Xiaoying Liu ◽  
Jinming Ji
Keyword(s):  
Treatment Group ◽  
Cerebral Infarction ◽  
Daily Living ◽  
Statistical Significance ◽  
Response Rates ◽  
Control Group ◽  
Activity Of Daily Living ◽  
Nihss Score ◽  
Before And After ◽  
The Difference

Objective: To evaluate the effect of butyphthalide in the treatment of massive cerebral infarction. Methods: One hundred and twenty patients with massive cerebral infarction who were admitted to the hospital between January 2017 and December 2017 were selected and divided into a treatment group (n = 60) and a control group (n = 60) using random number table, 80 each group. Patients in the control group were given conventional cerebral infarction therapy, while patients in the treatment group were given butyphthalide injection besides the conventional treatment. The National Institutes of Health Stroke Scale (NIHSS) score, score of activity of daily living (ADL), lipoprotein-associated phospholipase A2 (LP-PLA2) and prognosis were recorded and compared between the two groups. The response rates of the two groups were recorded. Results: The total response rates of the control group and treatment group were 73.85% and 93.85% respectively at the postoperative 21st day, and the difference had statistical significance (P<0.05). The NIHSS score of the two groups obviously decreased, and the ADL score significantly increased after treatment; the differences of NIHSS score and ADL score before and after treatment in the same group had statistical significance (P<0.05). The improvement of the indexes of the treatment group was obviously superior to that of the control group, and the differences between the two groups had statistical significance (P<0.05). The level of LP-PLA2 of both groups significantly decreased at the postoperative 21st day, and the difference before and after treatment in the same group was statistically significant (P<0.05); the treatment group had a significantly lower level of LP-PLA2 than the control group, and the difference had statistical significance (P<0.05). The treatment group had significantly higher positive outcome rate and lower mortality rate than the control group at the postoperative 90th day, and the differences had statistical significance (P<0.05). The incidence of adverse events of the treatment group and control group was 8.3% (5/60) and 5.0% (3/60) respectively, suggesting no significant difference (P>0.05). Conclusion: Butyphthalide has a favourable effect in treating massive cerebral infarction. It can repair neurologic impairment, improve activity of daily living, and adjust the level of LP-PLA2, suggesting favourable application values. How to cite this:Wang X, Sun Y, Dong S, Liu X, Ji J. Butyphthalide in the treatment of massive Cerebral Infarction. Pak J Med Sci. 2019;35(1):---------. doi: https://doi.org/10.12669/pjms.35.1.320 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Effects of integrated traditional Chinese and western medicine on the vision recovery and serum trace elements of patients with herpes simplex keratitis

2020 ◽  
Vol 7 (1) ◽  
pp. 19
Author(s):  
Sun Yan ◽  
Ling Feng ◽  
Xin Xiang-yang
Keyword(s):  
Trace Elements ◽  
Herpes Simplex ◽  
Clinical Efficacy ◽  
Western Medicine ◽  
Effective Rate ◽  
Control Group ◽  
Eye Drops ◽  
Observation Group ◽  
Immune Factor ◽  
Serum Trace Elements

Objective: To explore the effects of integrated traditional Chinese and western Medicine on the vision recovery and serum trace elements in patients with herpes simplex keratitis.Methods: A total of 86 cases of HSK patients admitted in Baogang Hospital of Inner Mongolia from January 2015 to October 2016 were selected and divided randomly into the observation group (n = 43) and the control group (n = 43) according to the random number table. The control group was treated with ganciclovir eye drops and chondroitin sulfate eye drops, and the observation group was treated with Qinggan Mingmu Decoction on the basis of the control group. The 2 groups were treated for 4 weeks continuously. The clinical efficacy was compared between two groups. The vision recovery, serum trace elements and tear immune factor levels were also compared between two groups before and after treatment.Results: After treatment, the effective rate of treatment in the observation group was significantly higher than that in the control group (p < .05); in the observation group of patients, visual analogue scale (VAS) score and visual acuity after treatment were obviously higher than those before treatment, and also remarkably higher than those in the control group of patients (p < .05); after treatment, the levels of Fe, Ca and Cu ions in the observation group were significantly lower than those in the control group and before treatment (p < .05); after treatment, the level of zinc ions in the serum in the observation group was significantly higher than that before treatment and in the control group (p < .05); after treatment, the levels of tear IgA, IgG and C3 in the observation group were prominently higher than those before treatment and in the control group (p < .05).Conclusions: In the treatment of HSK, integrated traditional Chinese and western medicine can promote effectively the vision recovery, regulate the level of trace elements in the serum and enhance the level of tear immune factors, with the clinical efficacy better than the treatment of western medicine alone.

scholarly journals Observations on the clinical efficacy of rhaFGF combined with Vitamin B complex for patients with Severe Recurrent Aphthous Ulcer

2021 ◽  
Vol 37 (7) ◽  
Author(s):  
Hui Sun ◽  
Jie Gao ◽  
Dan Li ◽  
Bing Li
Keyword(s):  
Therapeutic Effect ◽  
Clinical Efficacy ◽  
Clinical Symptoms ◽  
Effective Rate ◽  
Healing Time ◽  
Aphthous Ulcer ◽  
Control Group ◽  
Vitamin B ◽  
Observation Group ◽  
Creative Commons

Objectives: To observe the therapeutic effect of rha FGF combined with vitamin B complex on severe recurrent aphthous ulcers (RAUs). Methods: Ninety patients with severe RAU (grade III and IV) admitted to Chinese PLA General Hospital from May 2018 to May 2019 were selected and divided into two groups using a random number table, 45 patients/group. Patients in the control group gargled with a mixture of vitamin B complex (250 ml of 9% normal saline +250 ml of vitamin B complex +160,000 U of gentamicin +25 ml of lidocaine) after oral cleaning; patients in the observation group gargled with a mixture of the same ratio after oral cleaning and then sprayed rhaFGF on their oral ulcers. The clinical symptoms and treatment effects of the 2 groups within 1 week of medication were compared. Results: The total effective rate of treatment was 97.78% in the observation group and 82.22% in the control group; the difference was statistically significant (P <0.05). The time to ulcer pain disappearance and eating recovery and the ulcer healing time in the observation group were significantly shorter than those in the control group (P <0.05). Conclusion: rhaFGF combined with vitamin B complex has a significant therapeutic effect for patients with severe RAU; it can relieve pain and illness faster and shorten the healing time of ulcers. doi: https://doi.org/10.12669/pjms.37.7.4364 How to cite this:Sun H, Gao J, Li D, Li B. Observations on the clinical efficacy of rhaFGF combined with Vitamin B complex for patients with Severe Recurrent Aphthous Ulcer. Pak J Med Sci. 2021;37(7):---------. doi: https://doi.org/10.12669/pjms.37.7.4364 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Application of fine nursing in the drug resistance of Klebsiella pneumoniae and its influence on immune function

2021 ◽  
Vol 7 (6) ◽  
pp. 6585-6596
Author(s):  
Ying xi ◽  
Lu Yang
Keyword(s):  
Drug Resistance ◽  
Klebsiella Pneumoniae ◽  
Immune Function ◽  
Clinical Efficacy ◽  
Antimicrobial Agents ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Nursing Satisfaction ◽  
The Difference

Objective To explore the application of meticulous nursing in the drug resistance of Klebsiella pneumoniae (KPN) in children and its effect on immune function. Methods 100 children with KPN infection in our hospital from January 2020 to January 2021 were selected and randomly divided into the control group (50 cases) and the observation group (50 cases). The control group was given routine nursing, while the observation group was given fine nursing on the basis of the control group for 2 weeks. The clinical efficacy, KPN resistance, CD4 +, CD8 +, CD4 + / CD8 +, IgA, IgG, IgM levels and satisfaction were compared between the two groups. Results Compared with the control group (72.00%), the total clinical effective rate of the observation group (90.00%) was significantly increased, the difference was statistically significant (P < 0.05). The drug resistance of the observation group to a variety of antimicrobial agents was significantly higher than that of the control group, the difference was statistically significant (P < 0.05). Compared with before nursing, CD4 +, CD4 + / CD8 + were significantly increased, CD8 +, IgA, IgG, IgM were significantly decreased, the difference was statistically significant (P < 0.05). Compared with the control group (76.00%), the nursing satisfaction of the observation group was significantly higher (P < 0.05). Conclusion Fine nursing not only has a good application effect in children with KPN resistance, but also can significantly improve the immune function of children, which is worthy of clinical reference.

scholarly journals Clinical Efficacy of Neurointerventional Catheter Thrombolysis for Cerebral Infarction

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Qiangyuan Tian ◽  
Guangchao Zhu ◽  
Shugang Dong
Keyword(s):  
Cerebral Infarction ◽  
Clinical Efficacy ◽  
Neurological Deficit ◽  
Arterial Catheter ◽  
Control Group ◽  
Observation Group ◽  
Nihss Score ◽  
Before And After ◽  
Catheter Thrombolysis ◽  
Better Than

Objective: To analyze the clinical efficacy of neurointerventional catheter thrombolysis for cerebral infarction. METHODS: A total of 56 patients with cerebral infarction admitted to our hospital from April 2018 to June 2019 were enrolled for the experimental study. Two different treatments were applied to patients, and patients were divided into observation groups and controls according to different treatment methods. After grouped into two groups the control group was treated with intravenous thrombolysis. The observation group was treated with neurointerventional arterial catheter thrombolysis. The treatment effect, NIHSS score and BI index, neurological deficit score before and after treatment, and coagulation index were compared between the two groups. RESULTS: The therapeutic effect of the observation group (92.86%) was significantly different from that of the control group (67.86%), and the observation group was higher than the control group. The data of the observation group in the NIHSS score and the BI index were 5.42±1.77 and 95.64±2.15, respectively, which were better than the control group. The neurological deficit scores of the observation group before and after treatment were 19.88±6.24 and 9.14±5.81, respectively. After treatment, the difference was significant compared with the control group, p<0.05. The coagulation indexes of the observation group in FIB, PT, TT, etc. were respectively 3.68±1.04, 11.46±1.62, 15.37±2.46, all were better than the control group (2.13±0.47, 13.72±2.72, 19.85±2.62), P<0.05. Conclusion: the clinical efficacy of neurointerventional arterial catheter thrombolysis for cerebral infarction is significant, it can effectively promote the recovery of various functional conditions of patients with cerebral infarction, which is worthy of further application and promotion.

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