scholarly journals Observations on the clinical efficacy of rhaFGF combined with Vitamin B complex for patients with Severe Recurrent Aphthous Ulcer

2021 ◽  
Vol 37 (7) ◽  
Author(s):  
Hui Sun ◽  
Jie Gao ◽  
Dan Li ◽  
Bing Li
Keyword(s):  
Therapeutic Effect ◽  
Clinical Efficacy ◽  
Clinical Symptoms ◽  
Effective Rate ◽  
Healing Time ◽  
Aphthous Ulcer ◽  
Control Group ◽  
Vitamin B ◽  
Observation Group ◽  
Creative Commons

Objectives: To observe the therapeutic effect of rha FGF combined with vitamin B complex on severe recurrent aphthous ulcers (RAUs). Methods: Ninety patients with severe RAU (grade III and IV) admitted to Chinese PLA General Hospital from May 2018 to May 2019 were selected and divided into two groups using a random number table, 45 patients/group. Patients in the control group gargled with a mixture of vitamin B complex (250 ml of 9% normal saline +250 ml of vitamin B complex +160,000 U of gentamicin +25 ml of lidocaine) after oral cleaning; patients in the observation group gargled with a mixture of the same ratio after oral cleaning and then sprayed rhaFGF on their oral ulcers. The clinical symptoms and treatment effects of the 2 groups within 1 week of medication were compared. Results: The total effective rate of treatment was 97.78% in the observation group and 82.22% in the control group; the difference was statistically significant (P <0.05). The time to ulcer pain disappearance and eating recovery and the ulcer healing time in the observation group were significantly shorter than those in the control group (P <0.05). Conclusion: rhaFGF combined with vitamin B complex has a significant therapeutic effect for patients with severe RAU; it can relieve pain and illness faster and shorten the healing time of ulcers. doi: https://doi.org/10.12669/pjms.37.7.4364 How to cite this:Sun H, Gao J, Li D, Li B. Observations on the clinical efficacy of rhaFGF combined with Vitamin B complex for patients with Severe Recurrent Aphthous Ulcer. Pak J Med Sci. 2021;37(7):---------. doi: https://doi.org/10.12669/pjms.37.7.4364 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals The Efficacy of Tripterygium Glycosides Combined with LMWH in Treatment of HSPN in Children

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Yan Jin ◽  
Yanzheng Wang ◽  
Sai Wang ◽  
Qiongqiong Zhao ◽  
Donghua Zhang ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Clinical Symptoms ◽  
Effective Rate ◽  
Control Group ◽  
Clinical Effects ◽  
Observation Group ◽  
Significant Difference ◽  
Before And After ◽  
Qilu Hospital ◽  
Tripterygium Glycosides

Objective. This study aimed to explore the clinical efficacy and relevant mechanism of Tripterygium glycosides combined with low molecular weight heparin calcium (LMWH) in the treatment of Henoch–Schönlein purpura nephritis (HSPN) in children. Methods. 64 cases of children patients with HSPN treated at Qilu Hospital (Qingdao) from January 2015 to May 2020 were selected and randomly divided into the control group and the observation group and 32 cases in each group. Conventional medical treatment was applied in the two groups, besides which the control group was given LMWH while the observation group was given Tripterygium glycosides based on the control group. The clinical efficacy and the indexes of clinical symptoms of the two groups were compared. Immune globulin level, fibrinogen content (FIB), prothrombin time (PT), platelet level (PLT), and activated partial thromboplastin time (APTT) level of the two groups were compared before and after the treatment. Results. The total effective rate in the observation group was significantly higher than that of the control group, and the recurrence rate in the observation group was lower than that in the control group. After treatment, urine red blood cell count and 24 h urine protein were obviously better than those of the control group. There was no statistically significant difference in PT between the two groups of children before and after treatment. The levels of PLT and FIB in the two groups of patients after treatment were significantly lower than before treatment, and the PLT levels in the observation group were lower than those in the control group. Conclusion. The combination of Tripterygium glycosides and LMWH had good clinical effects in the treatment of children with HSPN, and it could improve the clinical symptoms, the mechanism of which might be related to the increase of PT, a decrease of PLT, and the improvement of coagulation function.

Analysis on Nursing Effect of Octreotide on Acute Pancreatitis

2021 ◽  
Vol 7 (4) ◽  
pp. 300-307
Author(s):  
Chenxia Wu ◽  
Li He
Keyword(s):  
Acute Pancreatitis ◽  
Clinical Symptoms ◽  
Nursing Intervention ◽  
Effective Rate ◽  
Occurrence Rate ◽  
Control Group ◽  
Observation Group ◽  
Clinical Value ◽  
Nursing Satisfaction ◽  
Satisfaction Scale

To explore the clinical value of octreotide therapy and nursing intervention in patients with acute pancreatitis. 120 patients with acute pancreatitis admitted to the Department of Digestive Medicine from June 2018 to August 2019 were selected. Two groups of patients were treated with octreotide. They were randomly divided into observation group (intensive nursing intervention) and control group (routine nursing) with 60 patients in each group. Compared with the control group (81.67%), the total effective rate (93.33%) was higher in the observation group (P<0.05%); After treatment, C reactive protein, lactate dehydrogenase, WBC and hemodiastase of patients in the observation group were better than those in the control group (P<0.05); compared with the control group (18.33%), the occurrence rate of hypoglycemia in the observation group (6.67%) was lower (P<0.05%); At the same time, the Nursing Satisfaction Scale of the observation group (95.00%) was higher than that of the control group (78.33%), (P<0.05%). Patients with acute pancreatitis treated with octreotide and strengthened nursing intervention can obtain more obvious therapeutic effect, so that the clinical symptoms and related laboratory indicators of patients have been significantly improved. At the same time, the clinical value was significant with a lower occurrence rate of hypoglycemia and higher nursing satisfaction scale.

scholarly journals Study on the clinical efficacy and mechanism of octreotide combined with thrombin in patients with liver

1970 ◽  
Vol 1 (1) ◽  
Author(s):  
Zhang Xiuqin
Keyword(s):  
Liver Cirrhosis ◽  
Liver Function ◽  
Clinical Efficacy ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Before And After ◽  
Octreotide Treatment ◽  
The Difference ◽  
Treatment Observation

Objective: To observe the clinical efficacy of octreotide and thrombin in the treatment of patients with liver cirrhosis, and to explore the mechanism of octreotide and thrombin. Methods: 53 patients with cirrhosis were randomly divided into control group and observation group from January 2014 to January 2016. The control group of 26 patients, given octreotide treatment. Observation group of 27 cases, given octreotide and thrombin combination therapy. Comparison of two groups of patients with clinical efficacy and changes in liver function before and after treatment. Results: The effective rate (88.89%) in the observation group was significantly higher than that in the control group (65.38%), the difference was statistically significant (p < 0.05). Before treatment, the difference of liver function between the two groups was not statistically significant (p > 0.05). After treatment, the liver function indexes of the two groups were improved, and the observation group was superior to the control group, the difference was statistically significant (p < 0.05).

scholarly journals Clinical Study of Xingnaojing Injection Combined with Craniocerebral Hypothermia Apparatus in the Treatment of Acute Hemorrhagic Stroke

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Xianfang Yue ◽  
Hua Zhou
Keyword(s):  
Clinical Efficacy ◽  
Daily Living ◽  
Hemorrhagic Stroke ◽  
Effective Rate ◽  
Control Group ◽  
Activity Of Daily Living ◽  
Observation Group ◽  
Nihss Score ◽  
Xingnaojing Injection ◽  
Acute Hemorrhagic Stroke

Objective: To investigate the clinical effect of Xingnaojing injection combined with craniocerebral hypothermia apparatus in the treatment of acute hemorrhagic stroke. Methods: Seventy-two patients with acute hemorrhagic stroke admitted to our hospital from March 2018 to September 2019 were randomly divided into two groups, with 36 cases in each group. The control group (n=36) was treated with craniocerebral hypothermia apparatus, and the observation group (n=36) was treated with Xingnaojing injection combined with craniocerebral hypothermia apparatus. The clinical efficacy, the National Institutes of Health Stroke Scale (NIHSS) score and the activity of daily living (MBI score) after 1 month of treatment were compared. Results: The effective rate of treatment in the observation group was higher than that in the control group (P < 0.05); NIHSS score was decreased in both groups (P < 0.05); MBI score was increased in both groups, and the change range of the observation group was greater than that of the control group, showing statistically significant differences (P < 0.05). Conclusion: Xingnaojing injection combined with craniocerebral hypothermia apparatus can improve the clinical efficacy, the neurological impairment and activity of daily living in the treatment of acute hemorrhagic stroke, which is worthy of clinical application.

scholarly journals Clinical Observation of Self-Made Yin-Tonifying Ophiopogonis Decoction Combined with Rehabilitation New Liquid in the Treatment of Reflux Esophagitis with Deficiency of Stomach Yin

2021 ◽  
Vol 5 (4) ◽  
pp. 112-116
Author(s):  
Liang Wang ◽  
Li Liu ◽  
Zhenghui Liu
Keyword(s):  
Reflux Esophagitis ◽  
Clinical Effect ◽  
Clinical Observation ◽  
Random Number ◽  
Clinical Symptoms ◽  
Total Effective Rate ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Random Number Table

Objective: To observe the efficacy of Yin-tonifying Ophiopogonis Decoction combined with Rehabilitation New Liquid in the treatment of reflux esophagitis (RE). Methods: Seventy-four patients with RE were included in the study and they were divided into an observation group and a control group using the random number table method with 37 cases in each group. The patients in the control group were given oral Yin-tonifying Ophiopogonis Decoction whereas the patients in the observation group were additionally treated with the Rehabilitation New Liquid. The clinical efficacy, traditional Chinese medicine (TCM) symptoms, and the efficiency of gastroscopy were compared between the two groups. Results: The total effective rate of clinical symptoms, TCM symptoms, and gastroscopy results between the observation group and the control group were significantly different (P < 0.05) and were statistically significant. Conclusion: The clinical effect of Yin-tonifying Ophiopogonis Decoction combined with the Rehabilitation New Liquid in the treatment of RE is significant.

Clinical Analysis of Qinglongdingchuan Decoction on Acute Exacerbation of Chronic Obstructive Pulmonary Disease

2021 ◽  
Vol 7 (5) ◽  
pp. 1357-1364
Author(s):  
Xiujiang Wang ◽  
Bo Yang ◽  
Rui Shi ◽  
Lixiu Zhang
Keyword(s):  
Treatment Group ◽  
Clinical Symptoms ◽  
Blood Gas Analysis ◽  
Effective Rate ◽  
Gas Analysis ◽  
Inflammatory Factors ◽  
Control Group ◽  
Chronic Obstructive ◽  
Observation Group ◽  
Obstructive Pulmonary Disease

Objective To explore the clinical effect of QinglongDingchuan Decoction on patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and analyze its mechanism. Methods From June 2017 to June 2019, patients with AECOPD were randomly divided into the observation group and the control group according to the time sequence of treatment, 40 cases in each group were observed. Control group: conventional western medicine treatment (controlled oxygen therapy, antibiotics, expectorants, bronchodilators, etc.), observation group: QinglongDingchuan decoction. 6 days is a course of observation. The routine pulmonary function, blood gas analysis, serum inflammatory factors, clinical symptoms and signs were observed. Results The observation group was superior to the control group in clinical control rate and effective rate (P < 0.05), suggesting that the treatment group was superior to the control group in overall effective rate. There were differences in symptoms, physical signs and total symptom scores between the two groups before and after treatment. The improvement of serum inflammatory factors in the treatment group was better than that in the control group. The improvement of PaC02 and Pa02 in the treatment group was better than that in the control group. Conclusion QinglongDingchuan decoction can better improve the clinical symptoms, physical signs, blood gas analysis indicators, improve the overall efficiency, and has a better effect on patients with fever AECOPD.

Clinical Impact of eCASH Combined with Nano-Silver Dressings for the Treatment of II Burn Wounds

2021 ◽  
Vol 11 (3) ◽  
pp. 359-365
Author(s):  
Minlie Yang ◽  
Xiaojin Zhou ◽  
Xian Ding ◽  
Yugang Zhu ◽  
Donglin Jiang ◽  
...  
Keyword(s):  
Effective Rate ◽  
Healing Time ◽  
Control Group ◽  
Observation Group ◽  
Bacterial Detection ◽  
Nano Silver ◽  
Burn Wounds ◽  
Degree Burn ◽  
Positive Rate ◽  
Second Degree

92 cases of second degree burn wounds treated in our hospital from January 2019 to December 2019 were selected as the research objects, and the clinical effect of eCASH concept treatment combined with nano silver dressing on the second degree burn wounds was studied. The patients were randomly divided into control group (n = 46) and observation group (n = 46). The control group was treated with conventional treatment combined with eCASH concept nursing, and the observation group was treated with eCASH concept combined with nano silver dressing. We found that the effective rate of the observation group was 95.65% higher than that of the control group (76.09%); the wound healing time of the observation group was significantly lower than that of the control group; the average VAS pain score of the observation group during wound treatment was significantly lower than that of the control group The total positive rate of bacterial detection in the observation group was 8.70%, which was lower than 28.26% in the control group; the incidence of complications in the observation group was 2.17% lower than that in the control group (17.39%); the differences were statistically significant (all P < 0.05). These results indicate that eCASH concept combined with nano silver dressing in the treatment of second degree burn wounds has a significant effect, which can accelerate the recovery, reduce the pain, and effectively reduce the total positive rate of bacterial detection and the incidence of complications.

CT Image Analysis of Large Bone Flap Craniotomy for Severe Traumatic Brain Injury

2019 ◽  
Vol 9 (8) ◽  
pp. 1741-1745
Author(s):  
Lihong Hu ◽  
Bo Yin ◽  
Ning Yin ◽  
Aiping Tan
Keyword(s):  
Therapeutic Effect ◽  
Total Effective Rate ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Craniocerebral Injury ◽  
Language Function ◽  
Function Score ◽  
Ct Image Analysis ◽  
Large Bone

Objective: To explore the therapeutic effect of large traumatic craniotomy for severe craniocerebral injury and examine recovery using CT image analysis. Methods: 86 patients with severe craniocerebral injury admitted to our hospital were selected and divided into control group (n = 43) and observation group (n = 43). The observation group was treated with modified large traumatic craniotomy, while the control group was treated with standard large traumatic craniotomy. After the experiment, we analyzed the CT images before and after the operation, as well as the therapeutic effect, including the total effective rate of drugs, the incidence of complications, intracranial pressure, neurological deficit, language function score and motor function score, and analyzed their medical value. Results: The medical total effective rate, language function score and motor function score of the observation group were higher than those of the control group, and the incidence of complications, intracranial pressure and neurological deficits were lower than those of the control group, with statistical significance (P < 0.05). CT images also showed that the patient condition was improved and recovery was good. Conclusion: Compared with standard craniotomy, the craniotomy with large bone flaps can achieve better therapeutic effect. The incidence of complications is reduced and the recovery is good. This type of procedure is beneficial to improve the prognosis and neurological function of patients.

scholarly journals Investigation of Therapeutic Effect of Traditional Mongolian Osteopathy Manual Reduction with Medicinal Wine Spraying Massage and Small Splint External Fixation Therapy for Treatment of Neerll-type Distal Humerus Fracture

2019 ◽  
Vol 3 (5) ◽  
Author(s):  
Tianhu Wei ◽  
Bada Rihu
Keyword(s):  
External Fixation ◽  
Therapeutic Effect ◽  
Total Effective Rate ◽  
Distal Humerus ◽  
Effective Rate ◽  
Humerus Fracture ◽  
Control Group ◽  
Observation Group ◽  
Distal Humerus Fracture ◽  
Manual Reduction

Objectives: To investigate the effect of traditional Mongolian osteopathy manual reduction with medicinal wine spraying massage and small splint external fixation therapy for treatment of Neerll-type distal humerus fractures. Methods: Sample selection was carried out during time period from November 2014 to May 2019. Sixty-six patients admitted to our hospital were selected as sample patients. The control group was given plaster treatment, while the observation group was given traditional Mongolian osteopathy manual reduction with medicinal wine spraying massage and small splint external fixation therapy. Efficacy for the two groups of patients was observed. Results: In this study, the total effective rate of observation group patients with treatment of traditional Mongolian osteopathy manual reduction with medicinal wine spraying massage and small splint external fixation therapy was 100%. Meanwhile, total effective rate of patients in control group was 87.88%. The difference was significant, p<0.05. Conclusions: In this study of clinical treatment, traditional Mongolian osteopathy manual reduction with medicinal wine spraying massage and small splint external fixation therapy could provide better therapeutic effect for treatment of patients with Neerll-type distal humerus fracture. At the same time, it reduces economic burden of patients. It has higher promotion value for clinical practice.

scholarly journals Clinical Study of Acupotomy Trinity Lysis Combined with Rehabilitation Training for Spastic Paralysis after Stroke

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Fajin Wang ◽  
Jianyong Gao ◽  
Lifeng Ma ◽  
Yali Hu ◽  
Yumin Yan ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Barthel Index ◽  
Training Group ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Spastic Paralysis ◽  
Rehabilitation Training ◽  
Post Stroke ◽  
The Difference

Objective: To study the clinical efficacy of acupotomy trinity lysis combined with rehabilitation training in the treatment of spastic paralysis after stroke, and to provide guidance for clinical diagnosis and treatment. Methods: From July 2019 to November 2020, 119 patients with post-stroke spastic paralysis who were admitted to our hospital's encephalopathy department were selected as the research objects, and 61 patients were divided into acupuncture combined with rehabilitation training group as the observation group by random number table method. 58 patients were divided into the rehabilitation training group as the control group. After 21 days of treatment, they passed the modified Ashworth Spasm Scale (MAS) grading scale score, Clinical Spasm Index (clinical spasm index, CSI) assessment, Fugl-Meyer exercise function scale (FMA) ) Score, Modified Barthel Index Score, and compare the clinical efficacy after treatment. Results: After treatment, the total effective rate of the observation group (95.08%) was higher than that of the control group (86.21%), and the difference was statistically significant (P?0.05); Before treatment, the contrast difference of MAS, FMA, CSI scores and modified Barthel index scores of the two groups of patients is not statistically significant; After treatment, the MAS scores and CSI scores of the elbow and knee joints of the observation group [(1.52±0.81)(1.46±0.83)(5.87±2.12)] were significantly lower than those of the control group [(2.17±0.68) (2.03±0.79)( 8.36±2.41)]; FMA upper limb and lower limb scores and modified Barthel index [(51.87±4.41)(30.21±5.05)(72.41±5.81)] of the observation group were significantly higher than those of the control group [(44.26±4.78)(28.45) ±4.23) (68.65±6.09)], the difference was statistically significant (P<0.05). Conclusion: Acupotomy trinity lysis combined with rehabilitation training is effective in treating patients with post-stroke spastic paralysis. It provides a safe, reliable and clinically effective new program, which is worthy of popularization and application.

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