Application of fine nursing in the drug resistance of Klebsiella pneumoniae and its influence on immune function

2021 ◽  
Vol 7 (6) ◽  
pp. 6585-6596
Author(s):  
Ying xi ◽  
Lu Yang
Keyword(s):  
Drug Resistance ◽  
Klebsiella Pneumoniae ◽  
Immune Function ◽  
Clinical Efficacy ◽  
Antimicrobial Agents ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Nursing Satisfaction ◽  
The Difference

Objective To explore the application of meticulous nursing in the drug resistance of Klebsiella pneumoniae (KPN) in children and its effect on immune function. Methods 100 children with KPN infection in our hospital from January 2020 to January 2021 were selected and randomly divided into the control group (50 cases) and the observation group (50 cases). The control group was given routine nursing, while the observation group was given fine nursing on the basis of the control group for 2 weeks. The clinical efficacy, KPN resistance, CD4 +, CD8 +, CD4 + / CD8 +, IgA, IgG, IgM levels and satisfaction were compared between the two groups. Results Compared with the control group (72.00%), the total clinical effective rate of the observation group (90.00%) was significantly increased, the difference was statistically significant (P < 0.05). The drug resistance of the observation group to a variety of antimicrobial agents was significantly higher than that of the control group, the difference was statistically significant (P < 0.05). Compared with before nursing, CD4 +, CD4 + / CD8 + were significantly increased, CD8 +, IgA, IgG, IgM were significantly decreased, the difference was statistically significant (P < 0.05). Compared with the control group (76.00%), the nursing satisfaction of the observation group was significantly higher (P < 0.05). Conclusion Fine nursing not only has a good application effect in children with KPN resistance, but also can significantly improve the immune function of children, which is worthy of clinical reference.

scholarly journals Study on the clinical efficacy and mechanism of octreotide combined with thrombin in patients with liver

1970 ◽  
Vol 1 (1) ◽  
Author(s):  
Zhang Xiuqin
Keyword(s):  
Liver Cirrhosis ◽  
Liver Function ◽  
Clinical Efficacy ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Before And After ◽  
Octreotide Treatment ◽  
The Difference ◽  
Treatment Observation

Objective: To observe the clinical efficacy of octreotide and thrombin in the treatment of patients with liver cirrhosis, and to explore the mechanism of octreotide and thrombin. Methods: 53 patients with cirrhosis were randomly divided into control group and observation group from January 2014 to January 2016. The control group of 26 patients, given octreotide treatment. Observation group of 27 cases, given octreotide and thrombin combination therapy. Comparison of two groups of patients with clinical efficacy and changes in liver function before and after treatment. Results: The effective rate (88.89%) in the observation group was significantly higher than that in the control group (65.38%), the difference was statistically significant (p < 0.05). Before treatment, the difference of liver function between the two groups was not statistically significant (p > 0.05). After treatment, the liver function indexes of the two groups were improved, and the observation group was superior to the control group, the difference was statistically significant (p < 0.05).

scholarly journals Effect of Psychological Intervention on Emotion of Patients with Tumor Radiotherapy

2021 ◽  
Vol 5 (5) ◽  
pp. 172-176
Author(s):  
Chao Wang ◽  
Bo Xiang ◽  
Bo Han
Keyword(s):  
Immune Function ◽  
Psychological Intervention ◽  
Nursing Intervention ◽  
Control Group ◽  
Observation Group ◽  
Nursing Satisfaction ◽  
Widespread Application ◽  
Self Rating ◽  
Clinical Nursing ◽  
The Difference

Objective: To explore the emotional impact of psychological nursing intervention on patients with malignant tumor radiotherapy, and further verify the specific application value of this nursing model in the oncology department. Methods: A total of 129 patients with tumor radiotherapy admitted to our hospital from June 2018 to June 2021 were selected as subjects, and they were divided into control group and observation group by random number method. Among them, 64 cases in the control group received routine clinical nursing. 65 cases in the observation group received psychological nursing intervention. Then, the clinical nursing effect, self-rating anxiety scale (SAS) score, self-rating depression scale (SDS) score, immune function level change condition and clinical nursing satisfaction were compared under the two nursing modes, in order to fully verify the clinical application value of psychological nursing intervention mode for patients with cancer radiotherapy. Results: Comparing the clinical indexes of the two groups, SDS and SAS scores of the observation group were significantly lower than those of the control group. In terms of nursing satisfaction, the observation group is 96.92% and the control group is 90.62%, the difference was significant, and had clinical statistical significance (P < 0.05); After the comprehensive evaluation of the immune function of the two groups, it was found that the observation group was significantly better than the control group, and the difference between the two groups was statistically significant (P < 0.05). Conclusion: In the mode of psychological nursing, medical staff can carry out precise psychological nursing intervention and nutritional nursing for patients according to the specific conditions and treatment process of patients, which can greatly promote the psychological stability of patients, significantly reduce patients’ negative emotions. In addition, the scientific implementation of psychological nursing intervention in the treatment of tumor radiotherapy patients can effectively strengthen the improvement of the immune function of patients, which has a very important application value to improve the physical function of patients, promotes the patient’s body rehabilitation, and is worth in the field of widespread application.

scholarly journals Clinical Study of Acupotomy Trinity Lysis Combined with Rehabilitation Training for Spastic Paralysis after Stroke

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Fajin Wang ◽  
Jianyong Gao ◽  
Lifeng Ma ◽  
Yali Hu ◽  
Yumin Yan ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Barthel Index ◽  
Training Group ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Spastic Paralysis ◽  
Rehabilitation Training ◽  
Post Stroke ◽  
The Difference

Objective: To study the clinical efficacy of acupotomy trinity lysis combined with rehabilitation training in the treatment of spastic paralysis after stroke, and to provide guidance for clinical diagnosis and treatment. Methods: From July 2019 to November 2020, 119 patients with post-stroke spastic paralysis who were admitted to our hospital's encephalopathy department were selected as the research objects, and 61 patients were divided into acupuncture combined with rehabilitation training group as the observation group by random number table method. 58 patients were divided into the rehabilitation training group as the control group. After 21 days of treatment, they passed the modified Ashworth Spasm Scale (MAS) grading scale score, Clinical Spasm Index (clinical spasm index, CSI) assessment, Fugl-Meyer exercise function scale (FMA) ) Score, Modified Barthel Index Score, and compare the clinical efficacy after treatment. Results: After treatment, the total effective rate of the observation group (95.08%) was higher than that of the control group (86.21%), and the difference was statistically significant (P?0.05); Before treatment, the contrast difference of MAS, FMA, CSI scores and modified Barthel index scores of the two groups of patients is not statistically significant; After treatment, the MAS scores and CSI scores of the elbow and knee joints of the observation group [(1.52±0.81)(1.46±0.83)(5.87±2.12)] were significantly lower than those of the control group [(2.17±0.68) (2.03±0.79)( 8.36±2.41)]; FMA upper limb and lower limb scores and modified Barthel index [(51.87±4.41)(30.21±5.05)(72.41±5.81)] of the observation group were significantly higher than those of the control group [(44.26±4.78)(28.45) ±4.23) (68.65±6.09)], the difference was statistically significant (P<0.05). Conclusion: Acupotomy trinity lysis combined with rehabilitation training is effective in treating patients with post-stroke spastic paralysis. It provides a safe, reliable and clinically effective new program, which is worthy of popularization and application.

Analysis on Nursing Effect of Octreotide on Acute Pancreatitis

2021 ◽  
Vol 7 (4) ◽  
pp. 300-307
Author(s):  
Chenxia Wu ◽  
Li He
Keyword(s):  
Acute Pancreatitis ◽  
Clinical Symptoms ◽  
Nursing Intervention ◽  
Effective Rate ◽  
Occurrence Rate ◽  
Control Group ◽  
Observation Group ◽  
Clinical Value ◽  
Nursing Satisfaction ◽  
Satisfaction Scale

To explore the clinical value of octreotide therapy and nursing intervention in patients with acute pancreatitis. 120 patients with acute pancreatitis admitted to the Department of Digestive Medicine from June 2018 to August 2019 were selected. Two groups of patients were treated with octreotide. They were randomly divided into observation group (intensive nursing intervention) and control group (routine nursing) with 60 patients in each group. Compared with the control group (81.67%), the total effective rate (93.33%) was higher in the observation group (P<0.05%); After treatment, C reactive protein, lactate dehydrogenase, WBC and hemodiastase of patients in the observation group were better than those in the control group (P<0.05); compared with the control group (18.33%), the occurrence rate of hypoglycemia in the observation group (6.67%) was lower (P<0.05%); At the same time, the Nursing Satisfaction Scale of the observation group (95.00%) was higher than that of the control group (78.33%), (P<0.05%). Patients with acute pancreatitis treated with octreotide and strengthened nursing intervention can obtain more obvious therapeutic effect, so that the clinical symptoms and related laboratory indicators of patients have been significantly improved. At the same time, the clinical value was significant with a lower occurrence rate of hypoglycemia and higher nursing satisfaction scale.

scholarly journals Clinical Observation of Zhuang Medicine Crystal Sugar Ye’An Decoction in Treating Senile Skin Pruritus and Its Effects on Serum IgE

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Yun Zhang ◽  
Yuying Lan
Keyword(s):  
Adverse Reactions ◽  
Clinical Observation ◽  
Skin Lesions ◽  
Effective Rate ◽  
Inflammatory Factors ◽  
Control Group ◽  
Observation Group ◽  
Serum Ige ◽  
The Difference ◽  
Lesion Severity

Objective: To discuss the specific application of Zhuang Medicine Crystal Sugar Ye’An Decoction in senile skin pruritus and its effects on serum IgE detection level. Methods: 90 patients with senile skin pruritus admitted to our hospital from February 2019 to April 2020 were randomly grouped. The general treatment effect, itching, secondary skin lesion severity, serum IL-6, IgE level and adverse reactions between 45 patients treated with Chlorcyclizine Hydrochloride Tablets (The control group) and 45 patients treated with Crystal Sugar Ye’An Decoction were compared. Results: The total effective rate of the treatment in the observation group was 93.33%, much higher than that in the control group, 75.56%. The difference was verified and statistically significant (P<0.05). Before the treatment, the itching area, frequency, duration and severity of secondary skin lesions were at the same level (P>0.05). After the treatment, the above data were all reduced, and the reduction of the observation group was more significant than that of the control group, indicating the difference was statistically significant (P<0.05). Before the treatment, there was no difference in serum IL-6 and IgE test data between the two groups (P>0.05). After the treatment, the tendency all declined, and that of the observation group was more obvious, indicating the difference was statistically significant (P<0.05). During the experiment, no obvious adverse reactions were observed in both groups. Conclusion: In the treatment of patients with senile pruritus, the application of Zhuang Medicine Crystal Sugar Ye’An Decoction is not only safe and reliable, but can promote the improvement of patients’ symptoms, adjust the level of inflammatory factors, and enhance clinical efficacy.

Arthroscopic Debridement Combined with Rehabilitation Training in the Treatment of Knee Osteoarthritis

2021 ◽  
Vol 7 (5) ◽  
pp. 3384-3388
Author(s):  
Wei Sun ◽  
Wenjie Yu ◽  
Yanhua Wang ◽  
Guangliang Hu
Keyword(s):  
Knee Osteoarthritis ◽  
Total Effective Rate ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Arthroscopic Debridement ◽  
Rehabilitation Training ◽  
The Difference ◽  
Score Result ◽  
Better Than

Objective: The clinical effect of arthroscopic debridement combined with rehabilitation training in the treatment of knee arthritis was studied and analyzed. Methods: A total of 90 patients with knee osteoarthritis treated in our hospital from August 2017 to August 2018 were selected as the research objects. All patients were divided into the observation group and the control group by using the random number method. The control group was treated by arthroscopic cleaning operation, and the observation group was treated by combined rehabilitation training on the basis of the treatment in the control group. The total effective rate and simple McGill pain of the two groups were compared Score and lyshoim score. Result: The total effective rate of the observation group was significantly higher than that of the control group (P < 0.05), the difference was statistically significant; after treatment, the simple McGill pain score of the observation group was significantly lower than that of the control group (P < 0.05), the difference was statistically significant, the lyshoim score of the observation group was significantly better than that of the control group (P < 0.05), the difference was statistically significant. Conclusion: In the treatment of knee osteoarthritis, arthroscopic debridement combined with rehabilitation training has a significant effect, which can significantly reduce the pain and improve the prognosis of patients. It is worth popularizing in clinical treatment.

Application and Statistical Health Analysis of Predictive Nursing in Orthopedic Nursing

2019 ◽  
Vol 9 (8) ◽  
pp. 1547-1552
Author(s):  
Fuqin Bao ◽  
Dapeng Wang ◽  
Hongyan Zhao ◽  
Bo Xu
Keyword(s):  
Preventive Measures ◽  
Control Group ◽  
Nursing Interventions ◽  
Observation Group ◽  
Nursing Satisfaction ◽  
Effective Manner ◽  
Orthopedic Care ◽  
The Difference ◽  
Nursing Guidelines ◽  
And Control

Objective: To investigate the application of predictive nursing guidelines in orthopedic care based on medical imaging and health statistics. Methods: 140 patients were divided into two groups: observation and control. The patients in the control group received routine nursing. The patients in the observation group received the guidance of predictive nursing on the basis of routine nursing. The nursing effects of the two groups were observed. Results: After the implementation of nursing interventions, the complication rate was 4.3% in the observation group and 20.0% in the control group. The difference between the groups was statistically significant (P < 0.05). The satisfaction rate was 97.1%, and the nursing satisfaction of the control group was 90.0%. The difference between the groups was statistically significant (P < 0.05). Discussion: Through observation of patient satisfaction and treatment, especially in orthopedics, patients are differentiated according to different diseases, and predictive care can effectively prevent complications. Conclusion: Predictive care provides preventive measures by comprehensively understanding and comprehensively assessing the patient's condition and developing care measures in a timely and effective manner.

scholarly journals Analysis of Clinical Effect of Treating Arrhythmia with Stable Heart Granules

2013 ◽  
Vol 2 ◽  
pp. 7
Author(s):  
Li Liu
Keyword(s):  
Clinical Practice ◽  
Adverse Reactions ◽  
Clinical Effect ◽  
Total Effective Rate ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
The Difference ◽  
And Control ◽  
Group Observation

<p><strong>Objective: </strong>To study the clinical effect on the treatment of cardiac arrhythmia, and further guide the clinical treatment. <strong>Method: </strong>From January 2011 to January 2013, 100 patients with arrhythmia were randomly divided into observation group and control group with 50 cases in each group. Observation group patients given oral Stable heart granule treatment, while control group was treated with oral propafenone treatment. The therapeutic effect and adverse reactions of the two groups were observed and compared. <strong>Results: </strong>The total effective rate of the observation group was higher than control group and incidence of adverse reactions was lower than control group, the difference was statistically significant, <em>p</em> &lt; 0.05. The use of stable heart particles in the treatment of arrhythmia produce significant effect. <strong>Conclusion: </strong>Clinical effect for Stable heart granule on arrhythmia was significant and should widely entrenched in clinical practice.</p>

scholarly journals Effect of Combining Early Chemotherapy with Zhipu Liujunzi Decoction under the Concept of Strengthening and Consolidating Body Resistance for Gastric Cancer Patients and Nursing Strategy

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Min Wang ◽  
Shujuan Wang ◽  
Qiang Su ◽  
Tian Ma
Keyword(s):  
Gastric Cancer ◽  
Immune Function ◽  
Cancer Patients ◽  
Remission Rate ◽  
Effective Rate ◽  
Control Group ◽  
Nursing Satisfaction ◽  
Body Resistance ◽  
Gastric Cancer Patients ◽  
Experimental Group

Objective. To explore the clinical efficacy of combining early chemotherapy with Zhipu Liujunzi decoction under the concept of strengthening and consolidating body resistance for gastric cancer patients and nursing strategy. Methods. The clinical data of 100 patients undergoing radical gastrectomy in our hospital from July 2019 to July 2020 were selected for the retrospective analysis, and the patients were divided into the control group and experimental group according to different treatment methods, with 50 cases in each group. Early chemotherapy after surgery was given to patients in the control group, and on the basis of the aforesaid treatment and under the concept of strengthening and consolidating body resistance, patients in the experimental group took Zhipu Liujunzi decoction and received the nursing strategy, so as to compare their effective rate, adverse reaction rate (ARR), immune function indicators, KPS scores, and nursing satisfaction scores. Results. After treatment, the experimental group obtained significantly higher objective remission rate (ORR) and disease control rate (DCR) ( P < 0.05 ), lower carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) levels ( P < 0.001 ), higher immune parameters levels ( P < 0.001 ), higher KPS scores and lower TCM symptom scores ( P < 0.001 ), lower PSQI scores, SAS scores, and SDS scores ( P < 0.001 ) and higher nursing satisfaction scores ( P < 0.001 ), and lower total accidence rate of toxic side effects ( P < 0.05 ) than the control group. Conclusion. Under the concept of strengthening and consolidating body resistance, combining early chemotherapy with Zhipu Liujunzi decoction is a reliable method for improving the immune function and quality of life for gastric cancer patients with higher safety. Such a strategy greatly reduces the tumor marker levels in patients. Further research will be conducive to establishing a better solution for gastric cancer patients.

scholarly journals The Efficacy of Tripterygium Glycosides Combined with LMWH in Treatment of HSPN in Children

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Yan Jin ◽  
Yanzheng Wang ◽  
Sai Wang ◽  
Qiongqiong Zhao ◽  
Donghua Zhang ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Clinical Symptoms ◽  
Effective Rate ◽  
Control Group ◽  
Clinical Effects ◽  
Observation Group ◽  
Significant Difference ◽  
Before And After ◽  
Qilu Hospital ◽  
Tripterygium Glycosides

Objective. This study aimed to explore the clinical efficacy and relevant mechanism of Tripterygium glycosides combined with low molecular weight heparin calcium (LMWH) in the treatment of Henoch–Schönlein purpura nephritis (HSPN) in children. Methods. 64 cases of children patients with HSPN treated at Qilu Hospital (Qingdao) from January 2015 to May 2020 were selected and randomly divided into the control group and the observation group and 32 cases in each group. Conventional medical treatment was applied in the two groups, besides which the control group was given LMWH while the observation group was given Tripterygium glycosides based on the control group. The clinical efficacy and the indexes of clinical symptoms of the two groups were compared. Immune globulin level, fibrinogen content (FIB), prothrombin time (PT), platelet level (PLT), and activated partial thromboplastin time (APTT) level of the two groups were compared before and after the treatment. Results. The total effective rate in the observation group was significantly higher than that of the control group, and the recurrence rate in the observation group was lower than that in the control group. After treatment, urine red blood cell count and 24 h urine protein were obviously better than those of the control group. There was no statistically significant difference in PT between the two groups of children before and after treatment. The levels of PLT and FIB in the two groups of patients after treatment were significantly lower than before treatment, and the PLT levels in the observation group were lower than those in the control group. Conclusion. The combination of Tripterygium glycosides and LMWH had good clinical effects in the treatment of children with HSPN, and it could improve the clinical symptoms, the mechanism of which might be related to the increase of PT, a decrease of PLT, and the improvement of coagulation function.

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