scholarly journals "Self-Cholesterol Measuring Devices Mission and CardioChek: Total Cholesterol, Triglycerides, High Density Lipoprotein (HDL)-Cholesterol Estimations in Whole Blood Samples"

2021 ◽  
Vol 35 (4) ◽  
Author(s):  
J Bolodeoku
Keyword(s):  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
Whole Blood ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
High Density ◽  
Blood Samples ◽  
Measuring Devices ◽  
Whole Blood Samples

Essential Data Derived from Biological Variation for Establishment and Use of Lipid Analyses

1989 ◽  
Vol 26 (3) ◽  
pp. 281-285 ◽  
Author(s):  
Robert P Ford
Keyword(s):  
General Population ◽  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Population Based ◽  
Reference Intervals ◽  
High Density ◽  
Healthy Individuals ◽  
Apparently Healthy

The analytical and biological components of variation of total cholesterol, high density lipoprotein (HDL) cholesterol, HDL3 cholesterol, HDL2 cholesterol and apolipoproteins A-I and B in serum were assessed in 12 apparently healthy individuals. All analytes showed marked individuality and therefore conventional population based reference intervals are of little use. The differences required for serial results to have changed significantly for these assays were calculated. The data presented confirm that the assays studied have limited value in screening the general population.

Procoagulant activities of plasma factor VIIc and factor Xc are positively and independently associated with concentrations of the high-density lipoprotein apolipoprotein, apo A-II

2008 ◽  
Vol 100 (09) ◽  
pp. 391-396 ◽  
Author(s):  
Maria Atta ◽  
David Crook ◽  
Faria Shafique ◽  
Desmond G. Johnston ◽  
Ian F. Godsland
Keyword(s):  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
Multivariable Analysis ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
High Density ◽  
Plasma Lipoproteins ◽  
In Vivo Studies ◽  
Plasma Factor

SummaryThe pro- and antiatherogenic roles of apolipoproteins B andA-I, respectively, are well-established although the importance of apolipoprotein A-II remains unclear. There is extensive evidence for the involvement of plasma lipoproteins in haemostatic function. However, in-vivo studies of relationships between haemostatic variables and apolipoprotein concentrations are very limited. Plasma fibrinogen, factors VIIc and Xc (FVIIc and FXc, respectively), apolipoproteins (apo) A-I, A-II and B, triglycerides, total, low-density and high-density lipoprotein (HDL) cholesterol, and cholesterol in HDL subfractions 2 and 3 were measured in 186 apparently healthy Caucasian men (aged 26–78 years; body mass index 19.9–37.8 kg/m2).Associations between haemostatic, apolipoprotein,lipid and lipoprotein variables were explored in uni- and multivariable analyses. Fibrinogen did not correlate with any of the lipid-related variables. FVIIc and FXc were significant positive univariate correlates of total cholesterol (correlation coefficients 0.26,p<0.001 and 0.19,p<0.05,respectively) triglycerides (0.37, p<0.001 and 0.36, p<0.001), and apoB (0.21, p<0.01 and 0.17, p<0.05) and apoA-II (0.19, p<0.05 and 0.29, p<0.001). HDL2 subfraction cholesterol correlated negatively with FVIIc and FXc (-0.20, p<0.01 and –0.22, p<0.01, respectively). In multivariable analysis, only the associations of FVIIc and FXc with total cholesterol, triglycerides and apoA-II remained statistically significant. In conclusion, total cholesterol and triglycerides were the major independent lipid correlates of FVIIc and FXc. The independent and positive associations of apoA-II with FVIIc and FXc suggest a prothrombotic involvement for this apolipoprotein

scholarly journals High-density-lipoprotein-cholesterol in protein–energy malnutrition

1982 ◽  
Vol 47 (3) ◽  
pp. 489-494 ◽  
Author(s):  
G. Oladunni Taylor ◽  
E. O. Agbedana ◽  
A. O. K. Johnson
Keyword(s):  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
Geometric Mean ◽  
Protein Energy Malnutrition ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
High Density ◽  
Low Density ◽  
Mean Values ◽  
Protein Energy

1. Plasma total cholesterol, high-density-lipoprotein (HDL)-cholesterol total protein, albumin and globulin levels were estimated in blood samples from thirty children with kwashiorkor, thirty-five with marasmus, twenty-eight with marasmic-kwashiorkor and twenty-seven control children.2. HDL-cholesterol was estimated after the very-low-density and low-density lipoproteins were precipitated from the plasma with heparin and manganese chloride.3. The distribution of HDL-cholesterol in the control and in the children with PEM was skewed and the range of values was wide. The values were independent of age and sex.4. After logarithmic transformation of the HDL-cholesterol and HDL-cholesterol: total cholesterol values, the geometric mean values for the three groups of children with PEM were significantly decreased when compared with values for the control children.5. The decrease in the mean HDL-cholesterol value for the children with kwashiorkor was more than for children with marasmus and marasmic-kwashiorkor.

Endurance training increased HDL cholesteryl ester metabolism in rats

1991 ◽  
Vol 70 (4) ◽  
pp. 1743-1747
Author(s):  
A. E. Pels ◽  
A. H. Terpstra ◽  
T. P. White
Keyword(s):  
High Density Lipoprotein ◽  
Cholesteryl Ester ◽  
Endurance Training ◽  
Residence Time ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
High Density ◽  
Cholesteryl Esters ◽  
Blood Samples ◽  
Significant Change

We studied the effects of endurance training on the metabolism of high-density lipoprotein (HDL, 1.063 less than density less than 1.15 kg/l) cholesteryl ester and proteins in rats fed a cholesterol-rich (1%) semipurified diet. The HDL were labeled with 131I in the apoproteins and with cholesteryl-[1-14C]oleate in the esters. The HDL were intravenously administered to endurance-trained (n = 10) and cage-sedentary (n = 10) rats. Blood samples were taken over the next 36 h while the rats were conscious and feeding. The trained rats had higher plasma HDL cholesterol (0.72 vs. 0.28 mM) and HDL apoprotein (461 vs. 267 mg/l) concentrations than the sedentary rats. The production or disposal rate of HDL cholesteryl ester was higher in the trained rats (1.36 mumol/h) than in the sedentary rats (0.72 mumol/h), whereas the production or disposal rate of HDL apoproteins was similar in the trained (0.64 mg/h) and sedentary (0.60 mg/h) rats. The residence time of the HDL cholesteryl esters (4.72 +/- 0.22 vs. 3.37 +/- 0.21 h) and HDL apoprotein (7.65 +/- 0.36 vs. 4.55 +/- 0.28 h) was longer for the trained than for the sedentary rats. These data indicate that endurance training resulted in a significant change in the metabolism of HDL cholesteryl esters and apoproteins as well as an increase in their concentrations.

scholarly journals Pre- and Post-Treatment Values of HDL Cholesterol and Total: HDL Cholesterol Ratio in Hyperlipoproteinaemic Subjects

1981 ◽  
Vol 18 (2) ◽  
pp. 71-75 ◽  
Author(s):  
John K Sale ◽  
James H Johnstone
Keyword(s):  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Blood Samples ◽  
Male And Female ◽  
Cholesterol Ratio ◽  
Type Iv ◽  
Cholesterol Levels ◽  
The Mean

High-density lipoprotein (HDL) cholesterol, total cholesterol, and triglyceride concentrations were measured in fasting blood samples from 74 controls and 185 patients with untreated primary hyperlipoproteinaemia. The mean HDL cholesterol levels and the total cholesterol: HDL cholesterol ratios were significantly different between male and female subjects. Only patients with Fredrickson type IV hyperlipoproteinaemia had HDL cholesterol concentrations significantly lower than the controls, but all subjects with hyperlipoproteinaemia had total: HDL cholesterol ratios significantly higher than control values. Subsequent investigations were performed on 31 patients during treatment of the hyperlipoproteinaemia by diet alone or in combination with clofibrate. Responses were variable, but generally improvements in the concentrations of triglyceride and total cholesterol were accompanied by an unchanged or decreased total: HDL cholesterol ratio, although there was not necessarily an increase in the HDL cholesterol itself.

scholarly journals Spirulina platensis effects on the levels of total cholesterol, HDL and triacylglycerols in rabbits fed with a hypercholesterolemic diet

2008 ◽  
Vol 51 (2) ◽  
pp. 405-411 ◽  
Author(s):  
Luciane Maria Colla ◽  
Ana Luiza Muccillo-Baisch ◽  
Jorge Alberto Vieira Costa
Keyword(s):  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
Spirulina Platensis ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
High Density ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Hypercholesterolemic Diet

In this work, hypercholesterolemia was induced in rabbits by feeding them a high cholesterol diet (CD, 350 mg/d) and the effects of supplementing this diet with 0.5 g/d Spirulina platensis was evaluated by measuring the levels of serum total-cholesterol (TC), triacylglycerols (TAG) and high-density lipoprotein (HDL-cholesterol) at the start of the experiment and after 30 d and 60 d. It was found that the levels of serum cholesterol decreased from 1,054±101 mg.dL-1 in the rabbits fed a CD without S. platensis to 516±163 mg.dL-1 to those fed with a high cholesterol diet supplemented with S. platensis (significant at p <0.0001). The addition of Spirulina to the cholesterolemic diet did not cause significative decrease on the levels of triacylglycerols in the animals. The levels of serum high-density lipoprotein (HDL-cholesterol) was 73±31 mg.dL-1 for rabbits fed a CD without S. platensis as compared to 91.0±15.7 mg.dL-1 in those fed a CD supplemented with S. platensis (significant at p=0.1533).

scholarly journals Importance of time interval between repeated measurements of total or high-density lipoprotein cholesterol when estimating an individual's baseline concentrations.

1987 ◽  
Vol 33 (10) ◽  
pp. 1913-1915 ◽  
Author(s):  
E P Rotterdam ◽  
M B Katan ◽  
J T Knuiman
Keyword(s):  
High Density Lipoprotein ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Repeated Measurements ◽  
High Density ◽  
Time Interval ◽  
Blood Samples ◽  
Asymptomatic Subject ◽  
Baseline Concentrations ◽  
Multiple Measurements

Abstract We studied intra-individual variation in total and high-density lipoprotein (HDL) cholesterol in healthy volunteers (22 men and 19 women, ages 19 to 62 years) on controlled natural diets. The within-person coefficient of variation (CV) depended on the interval between blood samples, increasing from about 2% to 3% for measurements made 24 h apart to 4% to 5% for measurements made at four-day intervals or longer. We conclude that within-subject fluctuations in total and HDL cholesterol have a time constant of several days. Multiple measurements are generally needed to decide whether an asymptomatic subject exceeds a certain concentration of total or HDL cholesterol; we recommend that such measurements be made at least four days apart.

Effect of time between measurements on within-subject variability for total cholesterol and high-density lipoprotein cholesterol in women

1994 ◽  
Vol 40 (5) ◽  
pp. 710-715 ◽  
Author(s):  
N Choudhury ◽  
P M Wall ◽  
A S Truswell
Keyword(s):  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Blood Cholesterol ◽  
Blood Samples ◽  
Sampling Intervals ◽  
Menstruating Women

Abstract A single blood cholesterol measurement may not accurately reflect an individual's true mean concentration. If duplicate blood samples are taken, what number of days between sampling gives the best chance of detecting the maximum within-subject variation? In this study, we analyzed 20 serial blood samples obtained from each of 13 healthy, menstruating women over 35 days. Variability was calculated as the semivariogram, which gives the average squared difference between replicate samples taken over a range of sampling intervals. Data were available for a complete set of intervals from 1 to 26 days. Variability in total cholesterol (TC) increased as the interval between sampling increased from 1 to 12 days. With high-density lipoprotein cholesterol (HDL-C), variability increased from 1- to 7-day intervals. In practice, our results suggest that, irrespective of the time of menstruation, the minimal interval for collecting a second blood sample for TC and HDL-C assays is approximately 2 weeks.

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