Meta / Dia Zwei unterschiedliche Zugänge zum Medialen

2010 ◽  
Vol 1 (2) ◽  
pp. 185-208 ◽  
Author(s):  
Dieter Mersch
Keyword(s):  
Literal Sense ◽  
Media Philosophy ◽  
Similar Vein

In media philosophy since Benjamin, the concept of medium is conceived in terms of »translation« or »transport«. In a similar vein, Christoph Tholen has brought the literal sense of »metaphor« as »meta-pherein« into focus. In my paper I argue that Tholen's approach misses the »meta« (»in the middle« or »beyond«) of »metaphor«, corresponding to the Latin »trans«. This is contrasted with the greek »dia« that allows the development of a performative notion of medium, which orients itself at material practices of transition.

scholarly journals The EBV-Encoded Oncoprotein, LMP1, Recruits and Transforms Fibroblasts via an ERK-MAPK-Dependent Mechanism

Pathogens ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 982
Author(s):  
Alexandra M Davis ◽  
Abigail Rapley ◽  
Christopher W Dawson ◽  
Lawrence S Young ◽  
Mhairi A Morris
Keyword(s):  
Tumour Microenvironment ◽  
Barr Virus ◽  
Erk Mapk ◽  
Lmp1 Expression ◽  
Epstein Barr ◽  
Similar Vein ◽  
Oncogenic Protein ◽  
Intense Debate ◽  
Dependent Mechanism

Latent membrane protein 1 (LMP1), the major oncoprotein encoded by Epstein–Barr virus (EBV), is expressed at widely variable levels in undifferentiated nasopharyngeal carcinoma (NPC) biopsies, fueling intense debate in the field as to the importance of this oncogenic protein in disease pathogenesis. LMP1-positive NPCs are reportedly more aggressive, and in a similar vein, the presence of cancer-associated fibroblasts (CAFs) surrounding “nests” of tumour cells in NPC serve as indicators of poor prognosis. However, there is currently no evidence linking LMP1 expression and the presence of CAFs in NPC. In this study, we demonstrate the ability of LMP1 to recruit fibroblasts in vitro in an ERK-MAPK-dependent mechanism, along with enhanced viability, invasiveness and transformation to a myofibroblast-like phenotype. Taken together, these findings support a putative role for LMP1 in recruiting CAFs to the tumour microenvironment in NPC, ultimately contributing to metastatic disease.

THE FLOW OF FLUIDS THROUGH ACTIVATED CARBON RODS.

1952 ◽  
Vol 30 (4) ◽  
pp. 348-371 ◽  
Author(s):  
E. A. Flood ◽  
R. H. Tomlinson ◽  
A. E. Leger
Keyword(s):  
Activated Carbon ◽  
Relative Pressure ◽  
End Effects ◽  
Flow Rates ◽  
Frequency Distributions ◽  
Literal Sense ◽  
Fine Grained ◽  
Porous Bodies ◽  
Carbon Rods ◽  
Flow Through

The flow rates of the vapors of benzene, ethyl chloride, diethyl ether, methanol, and water through activated carbon rods have been found to exceed, considerably, flow rates calculated by classical equations. The excess flow rates show maxima in widely different relative pressure regions and are ascribed to flow of adsorbed material. An empirical equation is presented which correlates the observed flow rates with relevant adsorption isotherms. Classical equations of flow through elliptical and rectangular pipes are discussed with reference to flow through fine-grained porous materials. It is shown that equations of the Adzumi type are roughly valid as applied to fine-grained porous bodies, but that without a knowledge of the frequency distributions of pore sizes and shapes, flow data cannot be related to pore dimensions in any literal sense. End effects are discussed.

Field and isotopic evidence for a c. 750 Ma tectonothermal event in Moine rocks in the Central Highland region of the Scottish Caledonides

1983 ◽  
Vol 73 (3) ◽  
pp. 119-134 ◽  
Author(s):  
M. A. J. Piasecki ◽  
O. van Breemen
Keyword(s):  
Crustal Rocks ◽  
Highland Region ◽  
Ductile Shearing ◽  
Central Highland ◽  
Isotopic Studies ◽  
Previous Hypothesis ◽  
Moine Rocks ◽  
Early Palaeozoic ◽  
Similar Vein ◽  
Tectonothermal Event

ABSTRACTEvidence is presented for a late Proterozoic, tectonothermal event which affected the rocks of the Moine assemblage in the Central Highland region of the Scottish Caledonides c. 750 Ma ago. This is about 200 Ma before the early Palaeozoic Grampian orogeny, whose effects are superimposed on the Moine rocks as well as dominating the tectonism in the Dalradian Supergroup.Field and isotopic studies are integrated in zones of ductile thrusting (sliding) which are typified by belts of tectonic schists with related swarms of quartz and muscovite-bearing pegmatite veins. Of particular significance is a ductile thrust (the Grampian slide) which separates deeper crustal rocks (the Central Highland division), interpreted as showing the imprint of the Grenville orogeny, from shallower rocks (the Grampian division) representing a supracrustal assemblage formed between the Grenville and the c. 750 Ma events.The Grampian slide is the structurally highest member of a system of related, previously unrecorded slides affecting the Central Highland division. New structural, petrographic and Rb-Sr isotopic data, obtained largely from a recently recognised inlier of the Central Highland division at Laggan, bear out that the quartz and pegmatite veins are segregations formed during ductile shearing under amphibolite facies conditions. Muscovites from these veins yield ages between 780 and 730 Ma, and a regression analysis of tectonic schists and the muscovites gives an age of 740 ± 40 Ma. These data substantiate our previous hypothesis that the deeper-seated Moine rocks were affected by a distinct orogenic event at 750 ± 30 Ma.In the Northern Highlands, similar vein swarms are related to the Sgurr Beag slide and to belts of previously unrecorded tectonic schists in the Glenfinnan division of the Moine assemblage. A new, 755 ± 8 Ma age obtained from such a tectonic schist at Kinloch Hourn, combined with previous, similar age data from lensoid pegmatites, imply that the c. 750 Ma event may have also affected the Morar and Glenfinnan divisions.

Human Performance Evaluation of a Metaphor Graphic Display for Respiratory Data

1994 ◽  
Vol 33 (04) ◽  
pp. 390-396 ◽  
Author(s):  
J. G. Stewart ◽  
W. G. Cole
Keyword(s):  
Performance Evaluation ◽  
Human Performance ◽  
Pattern Detection ◽  
Data Sets ◽  
Complex Task ◽  
Graphic Display ◽  
Literal Sense ◽  
Single Number ◽  
The Impact ◽  
Human Problem

Abstract:Metaphor graphics are data displays designed to look like corresponding variables in the real world, but in a non-literal sense of “look like”. Evaluation of the impact of these graphics on human problem solving has twice been carried out, but with conflicting results. The present experiment attempted to clarify the discrepancies between these findings by using a complex task in which expert subjects interpreted respiratory data. The metaphor graphic display led to interpretations twice as fast as a tabular (flowsheet) format, suggesting that conflict between earlier studies is due either to differences in training or to differences in goodness of metaphor, Findings to date indicate that metaphor graphics work with complex as well as simple data sets, pattern detection as well as single number reporting tasks, and with expert as well as novice subjects.

Psycho-Physical Union: The Problem of the Person in Descartes

Dialogue ◽  
1983 ◽  
Vol 22 (1) ◽  
pp. 23-46
Author(s):  
Murray Lewis Miles
Keyword(s):  
Philosophy Of Mind ◽  
Philosophy Of Nature ◽  
Literal Sense ◽  
Point Of Intersection ◽  
The Mind

The problem of the person may be described as the crux of Descartes' philosophy in the fairly obvious literal sense that it is the point of intersection of the two chief axes of the system, the Philosophy of Nature and the Philosophy of Mind. The actual, if not professed aim of the former is the ousting of the occult powers and faculties of Scholastic-Aristotelian physics by the mechanical concept of force or action-by-contact. The chief tenet of the latter is that mind, whose essence is thinking, is clearly and distinctly conceivable apart from matter, the essence of which is extension. From this, by an illicit inference which need not concern us further, Descartes concludes that the mind is “really distinct” from matter, that is, a substance capable of existing apart from body in its own right. Where these two lines of thought meet, the problem of the person constitutes itself in the following manner.

“Precondition for Victory”: Women’s Liberation in Mozambique and Guinea-Bissau

1978 ◽  
Vol 8 (1) ◽  
pp. 25-31
Author(s):  
Stephanie Urdang
Keyword(s):  
The Other ◽  
Women's Liberation ◽  
Guinea Bissau ◽  
Women’S Liberation ◽  
Participation Of Women ◽  
Full Participation ◽  
Similar Vein

A striking aspect of the on-going revolution in Mozambique and Guinea-Bissau is the insistence on the need for the liberation of women to be an explicit and integral part of that process. “Liberation of women,” reads an oft-quoted statement of Samora Machel, FRELIMO president, “is a fundamental necessity for our revolution; a guarantee of its continuity and a precondition for victory.” In a similar vein, Amilcar Cabral, assassinated leader of PAIGC, used to state firmly that their revolution could not be successful unless it ensured the full participation of women, or, “In Guinea-Bissau we say that women are fighting two colonialisms; one against the Portuguese and the other against men.”

Could there Be More than One Almighty?

1993 ◽  
Vol 29 (4) ◽  
pp. 465-495 ◽  
Author(s):  
T. W. Bartel
Keyword(s):  
Holy Spirit ◽  
Christian Doctrine ◽  
Literal Sense ◽  
The Past ◽  
The Holy Spirit ◽  
Doctrine Of The Trinity ◽  
The Trinity

If proof is required that yesterday's scandal can become today's fashion, we need look no further than recent discussions of the Christian doctrine of the Trinity. Just a generation ago, Trinitarians typically insisted that the members of the Godhead are not distinct persons in any literal sense. But during the past few years, more and more philosophically sophisticated Christians have unblushingly maintained that the Father, the Son, and the Holy Spirit are not just different persons, but different individuals – that the Trinity consists of three divine beings.

Sustainable Development in a Global Context: A Success or a Nuisance?

2015 ◽  
Vol 9 (1) ◽  
Author(s):  
Mohamed El-Kamel Bakari
Keyword(s):  
Sustainable Development ◽  
Trade Liberalization ◽  
Global Governance ◽  
Global Trade ◽  
Special Focus ◽  
Governance System ◽  
Global Context ◽  
The North ◽  
Similar Vein ◽  
The One

AbstractThis article argues that the evolution of, and challenges to, sustainable development cannot be understood completely outside its contemporary global context, consisting mainly of three interconnected spheres, i.e., the global governance system, the North-South debate, and global trade liberalization. As the boundaries of these three spheres get more and more blurred in a context of an intensifying globalization, the project of sustainable development is very often faced with obstacles that set back its evolution and might very well bring it to a halt. Above all, sustainable development is now caught in the crossfire between the push for exponential economic growth, on the one hand, and a compelling need to reverse catastrophic ecological threats and social exigencies, on the other. More often than not, the current structure and scope of global governance constitutes more of a hindrance than a help to the emerging paradigm of sustainable development. Accordingly, this article seeks to pinpoint the different challenges to the implementation of sustainable development in the field of global governance and to discuss to what extent these challenges are inherent in the structure and scope of this system. In a similar vein, this article examines and discusses the challenges to sustainability within two other highly interrelated spheres, namely global trade and the North-South politics. With this end in view, a special focus is placed throughout this paper on the interconnectedness of, and overlap between, these three global spheres and the determinant role played by the major actors therein.

Regionale Kompetenzzyklen – Zur Bedeutung von Produktlebenszyklus- und Clusteransätzen im regionalen Kontext

2001 ◽  
Vol 45 (1) ◽  
Author(s):  
Gunther Tichy
Keyword(s):  
Multiple Equilibria ◽  
New Product ◽  
The Other ◽  
Lower Probability ◽  
Product Cycle ◽  
Literal Sense ◽  
Information Density ◽  
Accelerating Expansion ◽  
Starting Conditions ◽  
Regional Product

AbstractModelling the path of the regional product cycle and adding dynamic and stochastic aspects suggests the likelihood of multiple equilibria; bunches of divergent paths of the product cycle may result, depending on starting conditions and parameter size. Narrow clusters of traditional products based on localisation economies, for instance, are quite likely to age, following the traditional bell-shaped path: accelerating expansion, congestion and Saturation, sclerosis and decline. Clusters based on urbanisation economies, on the other hand, face a much lower probability of aging, and if they do, they tend to pass the stages more slowly; their greater adaptability results from the higher information density of the region. Regions characterised by coexistence of several clusters are the ones most likely to avoid aging. Neither theoretical arguments nor historical examples, however, can be found in favour of a regional cycle in literal sense: a new product cycle following the declining one necessarily or at least with some likelihood.

Sign in / Sign up

Export Citation Format

Share Document