scholarly journals A Case Report of Multibacillary Leprosy Presenting with Multiple Outbreaks of Erythema Nodosum Leprosum

2019 ◽  
Vol 77 (1) ◽  
pp. 67-72
Author(s):  
R. Bouceiro-Mendes ◽  
A. Ortins-Pina ◽  
T. Marques ◽  
M. Viveiros ◽  
D. Machado ◽  
...  
Keyword(s):  
Erythema Nodosum ◽  
Mycobacterium Leprae ◽  
Endemic Region ◽  
Appropriate Care ◽  
Erythema Nodosum Leprosum ◽  
Mucous Membranes ◽  
Atypical Presentations ◽  
Multibacillary Leprosy ◽  
Skin Phototype

Leprosy is a chronic granulomatous disease with a long incubation period caused by Mycobacterium leprae that mainly affects the skin, mucous membranes and the peripheral nervous system. It carries the risk of per-manent sequels with a significant impact on the patient’s quality of life. It has a considerable clinically diver-sity and possible atypical presentations. We present a case of a 31-year-old, skin phototype V woman with multibacillary leprosy characterized by multiple outbreaks of erythema nodosum leprosum, as an inaugural manifestation of the disease. The disease was acquired within a group of children and adolescents from an endemic region of Africa, evolved untreated for 3 years, and presented with unusual features and remarkable lymphatic involvement. We highlight the importance of building and maintaining collaboration between expert centers and institutional partnerships in order to provide the adequate diagnostic resources and appropriate care to the affected populations.

scholarly journals A Retrospective Study: Epidemiology, Onset, and Duration of Erythema Nodosum Leprosum in Surabaya, Indonesia

2021 ◽  
Vol 33 (1) ◽  
pp. 8
Author(s):  
Cindy Fransisca ◽  
Iskandar Zulkarnain ◽  
Evy Ervianti ◽  
Damayanti Damayanti ◽  
Maylita Sari ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Retrospective Study ◽  
Erythema Nodosum ◽  
First Year ◽  
Erythema Nodosum Leprosum ◽  
Regular Control ◽  
Leprosy Patients ◽  
Multibacillary Leprosy

Background: Erythema nodosum leprosum (ENL) has a chronic and recurrent nature which could reduce patient’s quality of life in addition to the onset of ENL that occurs before, during, or after multidrug treatment, further emphasizing the importance of regular control and education.Purpose:This study aimed to evaluate the epidemiology, onset, duration, and recurrence of ENL. Methods:Data from medical records were obtained for a 3-year retrospective study of multibacillary leprosy patients at the Leprosy Division of the Dermatology and Venereology Outpatient Department, Dr. Soetomo General Hospital Surabaya, with a minimum of 2–5 years follow-up period.Result:The prevalence of  ENL continued to increase almost every year especially in 2017 (32% in 2015; 32% in 2016; and 36% in 2017). ENL most often occurs during the first year of multi-drug therapy (MDT) administration followed by after the release from treatment (RFT) with the latest onset occurring 4 years after RFT. The majority of patients experienced chronic and recurrent reactions with the longest reactions lasting up to 4.5 years (55 months). Conclusion:Knowledge about the onset, duration, and recurrences of ENL are essential, and strict supervision for routine control shall be encouraged to increase the patients’ compliance so as to increase their quality of life.

Unusual non-trophic ulcerations in leprosy: A case series of 17 patients

2021 ◽  
pp. 004947552199849
Author(s):  
Prakriti Shukla ◽  
Kiran Preet Malhotra ◽  
Parul Verma ◽  
Swastika Suvirya ◽  
Abir Saraswat ◽  
...  
Keyword(s):  
Erythema Nodosum ◽  
Case Series ◽  
Lepromatous Leprosy ◽  
Sweet Syndrome ◽  
Erythema Nodosum Leprosum ◽  
Leprosy Patients ◽  
Atypical Presentations ◽  
Neuropathic Ulcers

Non-neuropathic ulcers in leprosy patients are infrequently seen, and atypical presentations are prone to misdiagnosis. We evaluated diagnosed cases of leprosy between January 2017 and January 2020 for the presence of cutaneous ulceration, Ridley–Jopling subtype of leprosy, reactions and histologic features of these ulcerations. Treatment was given as WHO recommended multi-bacillary multi-drug therapy. We found 17/386 leprosy patients with non-neuropathic ulcers. We describe three causes – spontaneous cutaneous ulceration in lepromatous leprosy (one nodular and one diffuse), lepra reactions (five patients with type 1; nine with type 2, further categorised into ulcerated Sweet syndrome-like who also had pseudoepitheliomatous hyperplasia, pustulo-necrotic and necrotic erythema nodosum leprosum) and Lucio phenomenon (one patient). Our series draws attention towards the different faces of non-neuropathic ulcers in leprosy, including some atypical and novel presentations.

scholarly journals Health-Related Quality of Life amongst people affected by Erythema Nodosum Leprosum in Bangladesh: a Cross Sectional Study

2017 ◽  
Vol 88 (4) ◽  
pp. 488-498 ◽  
Author(s):  
Bob Bowers ◽  
C. Ruth Butlin ◽  
Khorshed Alam ◽  
Diana N.J. Lockwood ◽  
Stephen L. Walker
Keyword(s):  
Quality Of Life ◽  
Erythema Nodosum ◽  
Cross Sectional Study ◽  
Health Related Quality ◽  
Sectional Study ◽  
Cross Sectional ◽  
Erythema Nodosum Leprosum ◽  
Related Quality ◽  
Health Related

scholarly journals Effectiveness of the retreatment of patients with multibacillary leprosy and episodes of erythema nodosum leprosum and/or persistent neuritis: a single-center experience

2018 ◽  
Vol 93 (2) ◽  
pp. 181-184 ◽  
Author(s):  
Joel Carlos Lastória ◽  
Thaís Sampaio Corrêa de Almeida ◽  
Maria Stella de Mello Ayres Putinatti ◽  
Carlos Roberto Padovani
Keyword(s):  
Erythema Nodosum ◽  
Single Center ◽  
Single Center Experience ◽  
Erythema Nodosum Leprosum ◽  
Multibacillary Leprosy

scholarly journals Caracterização das Incapacidades Físicas em Pacientes Diagnosticados com Hanseníase Multibacilar Almenara-MG / Characterization of Physical Disabilities in Patients Diagnosed With Multibacillary Hansen's Disease in Almenara/MG

2020 ◽  
Vol 14 (52) ◽  
pp. 924-935
Author(s):  
Bianca Cândida Martins ◽  
Ednardo De Souza Nascimento ◽  
Viviane Amaral Toledo Coelho ◽  
Carla Giselly De Souza ◽  
Creonice Santos Bigatello ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Disabilities ◽  
Mycobacterium Leprae ◽  
Late Diagnosis ◽  
Hansen's Disease ◽  
Hansen’S Disease ◽  
Multibacillary Leprosy

Resumo: Hanseníase é uma doença infectocontagiosa, causada pelo Mycobacterium leprae. A principal característica da doença é o comprometimento dos nervos periféricos, que pode implicar em incapacidades físicas e deformidades.  Objetivo: Esta pesquisa objetivo apontar e caracterizar as incapacidades físicas que foram diagnósticas em pacientes com hanseníase multibacilar no município de Almenara-MG no período entre os anos de 2015 e 2019.  Metodologia: Trata-se de uma pesquisa bibliográfica, exploratória e descritiva. No primeiro momento foram buscados artigos e publicações em português, compreendendo os anos de 2002 a 2020. As buscas foram realizadas nas bases de dados como: Scielo, Portal Periódicos da Capes, Medline, revistas de enfermagem, e concomitantemente com um estudo prático realizado a partir de dados obtidos da cidade de Almenara – MG (SINAN) durante o período de 2015 á 2019. Resultados: Com o estudo pode-se constatar que no período compreendido a classificação operacional multibacilar foi a mais prevalente com um percentual de 79,01 % do total de casos, sendo neste percentual a prevalências em pacientes do gênero masculino (73,43%). Conclusão: A hanseníase HM (hanseníase multibacilar) é predominante no município de Almenara. Mais da metade dos pacientes analisados apresentaram incapacidades físicas de classificação grau I, o que gera incapacidade e diminuição da qualidade de vida ao indivíduo. Palavras – chave: Description; Multibacillary leprosy; Quality of life; Late diagnosis. 

Pediatric Leprosy Profile in the Postelimination Era: A Study from Surabaya, Indonesia

2022 ◽  
Author(s):  
Cita Prakoeswa ◽  
Novianti Reza ◽  
Medhi Alinda ◽  
M. Listiawan ◽  
Hok Bing Thio ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Erythema Nodosum ◽  
Elimination Rate ◽  
Mycobacterium Leprae ◽  
Tertiary Hospital ◽  
Disease Prevalence ◽  
Erythema Nodosum Leprosum ◽  
Common Problems ◽  
Endemic Areas ◽  
Frequent Exposure

Children who live in leprosy-endemic areas are susceptible to infection due to early and frequent exposure to Mycobacterium leprae. Indonesia is on the verge of eliminating this disease (prevalence rate < 1/10,000 population), but pediatric leprosy continues to occur in low-endemic areas. This study aimed to evaluate pediatric leprosy over a decade in a tertiary hospital in Surabaya, Indonesia. A retrospective study of leprosy in children under 15 years old between 2010 and 2019 was conducted in the Morbus Hansen Division, Outpatient Clinic at Dr. Soetomo Hospital in Surabaya, Indonesia. Seventy pediatric leprosy cases were identified between 2010 and 2019, consisting of 58 multibacillary (MB)-type cases and 12 paucibacillary (PB)-type cases. Slit skin smear (SSS) was positive in 26 cases. There were two cases of grade-2 disability and 15 cases of leprosy reaction (erythema nodosum leprosum) in children at the time of diagnosis. There was an insignificant decline in the number of pediatric leprosy cases in the last 10 years. Cases and disabilities in children were found in some leprosy pocket areas even though the national elimination rate has been achieved. MB infections, disability, and treatment defaults were common problems in pediatric leprosy.

Erythema nodosum leprosum as the presenting feature in multibacillary leprosy

2009 ◽  
Vol 15 (6) ◽  
Author(s):  
Smitha Prabhu ◽  
S D Shenoi ◽  
B Sathish Pai ◽  
H Sripathi
Keyword(s):  
Erythema Nodosum ◽  
Erythema Nodosum Leprosum ◽  
Multibacillary Leprosy
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