scholarly journals TYPE–II DIABETES MELLITUS;

2019 ◽  
Vol 26 (03) ◽  
Author(s):  
Ali Raza Memon ◽  
Allah Bux Ghanghro ◽  
Nasreen Qazi ◽  
Muhammad Akram ◽  
Imran Ali Shaikh
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Olive Oil ◽  
Control Group ◽  
P Value ◽  
Diabetic Patients ◽  
Study Group ◽  
Zero Level ◽  
Level Ii

Background: Diabetes Mellitus is the global health problem all over the world. The millions of people facing morbidity and mortality due to poor glycemic control with their complications. Now a days many researchers working on the benefits of natural remedies to control and cure different diseases like diabetes, hypertension, dyslipidemia etc. Aims & Objectives: To evaluate the therapeutic efficacy of (combination of olive oil & garlic) on glycemic control with comparison conventional allopathic therapy. Study Design: Prospective Randomized control Trial (RCT). Setting: Institute of Biochemistry Sindh University Jamshoro. Period: Three months from 15th July to 15th October 2017. Methodology: Collaboration of diabetic clinic medical wards LUMHS Jamshoro. Total 160 patients recruited and divided into two groups control and case study group. Anti-diabetic drugs were given both group with same dose and balanced diet, formulated capsules containing 1.1 ml of olive oil & 500mgs of garlic powder were given only patients of case study group for 12 weeks. Fasting blood sugar levels were analyzed by glucose oxidase method at zero level, level – I, level – II, while HbA1c% was detected by micro lab at zero level & level – II. Results: The results of our study; shows that serum fasting level significantly (p value = <0.001) reduce in case study group as compared to control group, glycemic control significant (p= <0.001) better observed in case study group as compare with control group. Conclusion: Our study concluded that components of olive oil and garlic have hypoglycemic effects with good glycemic control. With proper usage of garlic and olive oil in diet of diabetic patients can maintain glycemic control with in normal limits.

scholarly journals Influence of Nutrition Education with Calendar Method in Diabetic Patients' Blood Glucose

2018 ◽  
Vol 3 (2) ◽  
pp. 72
Author(s):  
Setyoadi Setyoadi ◽  
Heri Kristianto ◽  
Siti Nur Afifah
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Nutrition Education ◽  
Community Health Center ◽  
Control Group ◽  
P Value ◽  
Diabetic Patients ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Before And After

Diabetes mellitus is a disease that required good self-management. Noncompliance in diet and meal plans cause the instability of blood glucose levels. Nutrition education calendar method can improve knowledge and ability to consume food that matches the number, hours and types with dietary adjustments listed in the calendar diet. This study aimed to determine the effect of nutrition education calendar method on blood glucose levels of patients with type 2 diabetes mellitus in Community Health Center Pakis Malang. Pre-experimental design one group pretest-posttest with purposive sampling was conducted in this study and sample obtained as many as 21 people. Blood glucose levels were measured before and after the nutrition education calendar methods. Compliance in using calendar method with the observation sheet. Statistical analysis values obtained by Wilcoxon, the p-value of 0.007 (p <0.05). The results of the analysis, 16 respondents showed a decrease in blood glucose levels and 5 respondents experienced an increase in blood glucose levels after the given intervention. It can be concluded that there are differences between blood glucose levels before and after nutrition education calendar method. Differences in blood glucose levels can be influenced by controlling diet respondent in accordance with the calendar method in education, but also antidiabetic drugs, and sports. Should be added to the control group to determine objectively the effect of nutrition education on the calendar method.

scholarly journals α-2-Macroglobulin in Saliva Is Associated with Glycemic Control in Patients with Type 2 Diabetes Mellitus

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Juan Pablo Aitken ◽  
Carolina Ortiz ◽  
Irene Morales-Bozo ◽  
Gonzalo Rojas-Alcayaga ◽  
Mauricio Baeza ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Control Group ◽  
Diabetic Patients ◽  
Promising Alternative ◽  
Positive Discrimination ◽  
And Control

Background. Subjects with type 2 diabetes mellitus (DM2) require an adequate glycemic control to avoid diabetic complications. Currently, saliva biomarkers are used as a diagnostic tool and can be indicative of the degree of progression and control of various diseases. Several studies indicate thatα-2-macroglobulin levels are elevated in diabetic patients.Methods. 120 subjects with DM2 were enrolled and classified into two groups according to their glycemic control (percentage of glycated hemoglobin-A1c (HbA1c), <7% adequate glycemic control group; >7% inadequate glycemic control group). The relationship betweenα-2-macroglobulin levels from saliva samples and HbA1c was subsequently evaluated.Results. We found a positive correlation betweenα-2-macroglobulin and HbA1c (r=0.778andP<0.0001). Area under the receivers operating characteristic (ROC) curve ofα-2-macroglobulin indicated a positive discrimination threshold ofα-2-macroglobulin (AUC = 0.903, CI 95%: 0.847–0.959,P<0.0001) to diagnose glycemic control.Conclusions. Our data strongly suggest that the level of salivaα-2-macroglobulin is an indicator for the degree of glycemic control in diabetic patients and represents a promising alternative method to evaluate this parameter.

scholarly journals Is the central corneal thickness of diabetic patients thicker than that of non-diabetics’ eyes?

2015 ◽  
Vol 74 (1) ◽  
Author(s):  
Solani D. Mathebula ◽  
Tshegofatso M. Segoati
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Central Corneal Thickness ◽  
Statistical Significance ◽  
Corneal Thickness ◽  
Control Group ◽  
Diabetic Patients ◽  
Study Group ◽  
Group 3 ◽  
The Mean

The purpose of the study was to evaluate central corneal thickness in diabetic patients and to compare the results with controls without diabetes mellitus. Sixty-five diabetic patients (65 eyes) constituted the study group, and 50 eyes were from the healthy control group (50 non-diabetic patients). The study group was subdivided into group 1 (no diabetic retinopathy, n = 35), group 2 (mild to moderate nonproliferative diabetic retinopathy, n = 20), and group 3 (proliferative diabetic retinopathy, n = 10). Central corneal thickness measurements in microns were determined using ultrasound pachymetry. The mean central corneal thickness was significantly greater in the study group (567.14 μm ± 14.63 μm) than in the control group (531.14 μm ± 5 μm). In addition, the mean central corneal thickness was found to be greater in group 3 (577 μm ± 12 μm) than in groups 1 (562 μm ± 13 μm) and 2 (566.86 μm ± 15 μm), but the difference did not reach statistical significance. We found that the mean central corneal thickness for diabetic patients was thicker than that of the healthy controls. Thicker central corneas associated with diabetes mellitus should be taken into consideration when obtaining accurate intraocular pressure measurements in diabetics.

scholarly journals Effect of hypothyroidism on lipid profile of type 2 diabetic patients

2020 ◽  
Vol 7 (5) ◽  
pp. 754
Author(s):  
Damanpreet Singh ◽  
Gurinder Mohan ◽  
Arshdeep Bansal
Keyword(s):  
Type 2 Diabetes ◽  
Lipid Profile ◽  
Diabetic Complication ◽  
Control Group ◽  
P Value ◽  
Diabetic Patients ◽  
Study Group ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

Background: Hypothyroidism is an endocrine disorder resulting from deficiency of thyroid hormones, and Diabetes is a metabolic disorder that share the phenotype of hyperglycaemia. Both the endocrinopathies have been found to be associated with dyslipidaemia and atherosclerosis that result into various complications. Our aim was to assess the difference of dyslipidaemia in patients suffering from hypothyroidism with diabetes as compared to diabetes alone.Methods: Study was conducted in department of medicine in SGRDIMSR, Sri Amritsar. A total of 120 patients were enrolled for the present study, the one who presented to hospital from January 2018 to August 2019 diagnosed with diabetes mellitus type 2. The patients were divided into two groups. 60 patients having type 2 diabetes without hypothyroidism (control group). 60 patients having type 2 diabetes with hypothyroidism (study group). Fasting lipid profile were performed in both the groups and were analysed for the study.Results: Dyslipidaemia was seen more in study group as compared to control group with mean cholesterol of 488.3(±144.43) and mean triglyceride levels of 354.30(±128.57) in study  group as compared to control group with mean cholesterol and triglyceride levels of 179.7(±81.47) and 177.08(±118.18) with p-value of 0.001 and 0.01 respectively which were significant. Also, obesity and diabetic complication were more in patients of dual endocrinopathies as compared to diabetes alone which were also significant statistically.Conclusions: From our study it is concluded that type 2 diabetes with hypothyroidism causes more dyslipidaemia as compare to type 2 diabetes alone. So proper screening of thyroid profile of type 2 diabetic patients and its correction helps in achieving better lipidemic control which further prevent complications.

scholarly journals A comparative prospective randomised controlled study for mesh fixation by cyanoacrylate glue versus prolene sutures in patients undergoing Lichtenstein hernioplasty

2019 ◽  
Vol 7 (1) ◽  
pp. 83
Author(s):  
Dheer S. Kalwaniya ◽  
Satya V. Arya ◽  
Sumedha Gupta ◽  
Manigandan Kuppuswamy ◽  
Jaspreet S. Bajwa ◽  
...  
Keyword(s):  
Inguinal Hernia ◽  
Mesh Fixation ◽  
Operating Time ◽  
Control Group ◽  
P Value ◽  
Study Group ◽  
Cyanoacrylate Glue ◽  
Post Operative Pain ◽  
Significant Difference

Background: Inguinal hernia repair is one of the most commonly performed procedures by general surgeons. Cyanoacrylate is the generic name for a family of fast acting adhesives. The aim of the present study done in Department of General Surgery, Safdarjung Hospital, New Delhi was to compare the newer emerging technique of mesh fixation.Methods: A total of sixty patients were included in the present study and were allotted in case and control group randomly by sealed envelope technique. In case (study) group, all the patients underwent mesh fixation by cyanoacrylate glue and in control group, by prolene 3-0 sutures.Results: Most frequency in age group 31-40 yrs, males:females ratio >1 and right sided inguinal hernia was more common. Bi-lateral hernia was common in elderly. Indirect: direct ratio 4.5:1. Operating time period for the patients of the case (study) group is less than control group. P value of post-operative pain in immediate post-operative period (day 1 and 2) and POD 30, 60 and 90 was not of clinical significance whereas the p-value on 6,120,150 and 180 post op day was of clinical significance. In our study, there was a case of incidental observation: a) reaction due to use of cyanoacrylate glue, b) rejection of mesh for which mesh had to be removed.Conclusions: There is no statistically significant difference between mesh fixation with cyanoacrylate glue and mesh fixation by prolene suture techniques in immediate post-operative pain. Statistically significant difference favoring mesh fixation by cyanoacrylate glue technique was seen with respect to operating time and post-operative groin pain with increasing post-operative duration.

scholarly journals Clinicopathological Impact of Diabetes Mellitus in Pulmonary Tuberculosis Patients

2019 ◽  
Vol 32 (1) ◽  
pp. 46-53
Author(s):  
Nazmul Hoque Munna ◽  
Md Mohiuddin Ahmed ◽  
Mohammad Imtiaj Mahbub
Keyword(s):  
Diabetes Mellitus ◽  
Pulmonary Tuberculosis ◽  
Normal Population ◽  
Clinical Impact ◽  
Diabetic Group ◽  
Control Group ◽  
P Value ◽  
Diabetic Patients ◽  
Directly Observed Therapy ◽  
Pulmonary Tb

Background: Tuberculosis (TB) is the one of the leading cause of death globally, more marked in developing countries like Bangladesh. The prevalence of Diabetes Mellitus (DM) is increasing globally fueled by obesity endemic. The study is designed to get an idea about prevalence and clinical impact of DM among pulmonary TB patients. Objective: The aim of the study is to find out the rate and effect of Diabetes mellitus in patients with pulmonary Tuberculosis. Material and Methods: This was a cross sectional study conducted in DOTS (directly observed therapy, short course) corner, outpatient department (OPD), Dhaka Medical College & Hospital, Dhaka from July to December 2012. 125 patients of pulmonary Tuberculosis were included in this study as case. 125 age and sex matched controls who were not suffering from pulmonary Tuberculosis were taken from the attendant of the patients who had given the consent. Prevalence and clinical impact of diabetes mellitus was sort out in both case and control group and compared with each other. Results: The study shows the prevalence of DM among pulmonary TB patients is 26.4% and among normal population (non TB patients) is 20.8%. The relative risk (odds ratio) of DM among pulmonary TB patients is 1.27 times more than non TB person with p-value - 0.02, which is significant. In symptoms analysis, diabetic patients have got more haemoptysis (45%), in contrast to non-diabetic group (13%), with p-value-0.001. In non-diabetic patients Fever are more common, 88% in contrast to diabetic group 57%, p-value-0.001. Sputum positivity is more common (69%) among diabetic pulmonary TB patients than non diabetic pulmonary TB patients (58%). On chest X ray findings this study reveals that pulmonary TB patient with DM having cavitary lesion is 33% while it is only 9.76% in non-diabetic persons. Conclusion: This study found that there was greater prevalence of DM among pulmonary TB patients (26.4%) than non pulmonary TB persons (20.4%). This findings provides the information that health care provider should intensively search presence of DM in pulmonary TB patients. TAJ 2019; 32(1): 46-53

scholarly journals Android based Diabetic Manager to Enhance Compliance and to Control Blood Glucose Level among Type 2 Diabetic Patients in Magelang, Central Java, Indonesia

Webology ◽  
2021 ◽  
Vol 18 (1) ◽  
pp. 179-191
Author(s):  
Heru Supriyatno ◽  
Dwi Ari Murti Widigdo ◽  
Wiwin Renny Rahmawati
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Patient Adherence ◽  
Control Group ◽  
P Value ◽  
Diabetic Patients ◽  
The Status ◽  
And Control

Android Based Diabetic Manager (ABDM) is an application used for diabetic patients to control their diet. This application is an easy way to remind them in consuming foods and giving them alert when its necessary calories have been achieved. This study was conducted in response to technological developments in the Era 4.0 to help people with Type 2 Diabetes Mellitus through diet control that can be done independently. This study was conducted in the city of Magelang aimed to evaluate whether using ABMD was effective to improve patients adherence in their diet and to control their blood glucose levels. This experimental study was using pre test and post test with control group design. By using simple random sampling, 52 people suffering from Type 2 Diabetes Mellitus recruited in this study devided into two groups, ABDM group and control group. The Pearson Chi-Square test result showed that there was significantly different between ABDM group and control group in the status of blood glucose control and patient adherence with p value was 0.048and 0.000 respectively (p value <0.05). This result indicated that H0 was rejected and H1 was accepted, which could be interpreted that Android based Diabetic Managerapplication influenced the status of blood sugar control and improved the patient adherence in managing their diet. Android based Diabetic Managerapplication influenced the status of blood sugar control and improved the patient adherence in managing their diet. Recomendation was made to conduct future study in the wider Diabetes community by adding more complete types of menu list and its variations in the Android based Diabetic Manager.

scholarly journals Effect of sulfonylureas on attenuation of electrocardiographic ST- segment elevation during an acute myocardial infarction in diabetics

2018 ◽  
Vol 7 (4) ◽  
pp. 579
Author(s):  
Bapugouda Sahebagouda Patil ◽  
Naser Ashraf Tadvi
Keyword(s):  
Diabetes Mellitus ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Control Group ◽  
Diabetic Patients ◽  
Study Group ◽  
St Segment Elevation ◽  
St Segment ◽  
Significant Difference ◽  
The Mean

Background: Sulfonylureas are primarily used in the treatment of diabetes mellitus act by inhibiting ATP sensitive potassium ATP (K-ATP) channels. Similar channels are also present are also present in heart venticular muscle. Previous studies reveal that these drugs are able to reduce the electrocardiographic ST- segment elevation changes during an acute myocardial infarction. Hence, the present study was designed to evaluate the attenuating effect of sulfonylureas on ST- segment elevation in diabetic patients presenting with acute myocardial infarction.Methods: This cross sectional study included 73 diabetic patients presenting with the signs and symptoms of acute myocardial infarction of less than 24 hours duration along with CPK levels of more than 25 IU/L. Of them 5 were excluded from the study. The remaining 68 patients were included in the study, out of which 36 patients were in the study group (sulfonylurea group), and 32 patients were in the control group (non-sulfonylurea group).Results: No statistically significant difference was seen in the demographic parameters like age, sex, duration of diabetes mellitus and CPK levels (p>0.05). Among 68 patients 38 patients were diagnosed as STEMI. The mean magnitude of ST-elevation in the study group (n=16) was 2.3±0.12 and in control group (n=22) patients it was 3.7±0.33. The percentage of NSTEMI was significantly higher in study group compared to control. Statistically significant difference (p<0.05) was seen only between CPK level of range 25 and 100IU/L and mean magnitude of ST-segment elevation in STEMI patients. Significant difference in the mean magnitude of ST-segment elevation was observed in case of females among the study and control groups (p<0.05).Conclusions: Sulfonylureas drugs play a significant role in attenuation of ST-segment in diabetic patients presenting with acute myocardial infarction. Further, large multicentric studies are required to confirm the exact correlation between sulfonylureas and ST-segment.

TYPE II DIABETES MELLITUS: A WARNING SIGN FOR DEPRESSION

2019 ◽  
Author(s):  
Aisha Khan Jadoon
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Depressive Symptoms ◽  
Glycemic Control ◽  
Functional Limitation ◽  
Depression Scale ◽  
Control Group ◽  
Warning Sign ◽  
Diabetic Patients

Background: People with type 2 diabetes compared to those without seem to have more chances of developing depressive symptoms. Diabetes leads to depression or vice versa, remains an unsolved puzzle. Diabetes and depression together leave deep psychological and physical imprints on their victims leading to functional limitation, poor quality of life and raised mortality rate. Diabetic patients should be warned by the physicians to keep a watch for the development of depressive symptoms in them. The study aimed to investigate the relationship between type 2 diabetes mellitus and depression. Methods: The cross sectional study was conducted at Ziauddin University Hospital over a period of six months. Sample size of 100 was taken. Details of participant’s demographics along with Body Mass Index were recorded. Questionnaires were filled by researchers. SRQ 20 depression scale was used to diagnose depression. Data was entered and analyzed by version 20 of SPSS. Results: Different demographic and social variables were assessed in this study. 100 patients with HbA1c <6.5% were taken and 100 with ≥ 6.5%. 73 (36.5%) patients out of the total sample were depressed, almost from the good glycemic control group. Only a quarter of patients that had normal HbA1c levels became depressed however 48% patients with poor glycemic control suffered depression. Conclusion: Research concludes that co-morbid diabetes and depression is not a rare finding. Risk factors must be ruled out and the chances to develop depression should be identified at an earlier stage before complications worsen the condition.

scholarly journals Polypharmacy in Type 2 Diabetes Mellitus: Insights from an Internal Medicine Department

Medicina ◽  
2019 ◽  
Vol 55 (8) ◽  
pp. 436 ◽  
Author(s):  
Elena-Codruța Dobrică ◽  
Mihnea-Alexandru Găman ◽  
Matei-Alexandru Cozma ◽  
Ovidiu Bratu ◽  
Anca Pantea Stoian ◽  
...  
Keyword(s):  
Internal Medicine ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Drug Interactions ◽  
Control Group ◽  
Diabetic Patients ◽  
Study Group ◽  
Diabetes Patients

Background and Objectives: Polypharmacy heavily impacts the quality of life of patients worldwide. It is a necessary evil in many disorders, and especially in type 2 diabetes mellitus, as patients require treatment both for this condition and its related or unrelated comorbidities. Thus, we aimed to evaluate the use of polypharmacy in type 2 diabetes mellitus vs. non-diabetes patients. Materials and Methods: A cross-sectional retrospective observational study was conducted. We collected the medical records of patients hospitalized in the Internal Medicine Clinic of the Clinical Emergency Hospital of Bucharest, Romania, for a period of two months (01/01/2018–28/02/2018). Patients diagnosed with type 2 diabetes mellitus were included in the study group, whereas patients who were not diabetic were used as controls. Results: The study group consisted of 63 patients with type 2 diabetes mellitus (mean age 69.19 ± 9.67 years, range 46–89 years; 52.38% males). The control group included 63 non-diabetes patients (mean age 67.05 ± 14.40 years, range 42–93 years, 39.68% males). Diabetic patients had more comorbidities (10.35 ± 3.09 vs. 7.48 ± 3.59, p = 0.0001) and received more drugs (7.81 ± 2.23 vs. 5.33 ± 2.63, p = 0.0001) vs. non-diabetic counterparts. The mean number of drug-drug and food-drug interactions was higher in type 2 diabetes mellitus patients vs. controls: 8.86 ± 5.76 vs. 4.98 ± 5.04, p = 0.0003 (minor: 1.22 ± 1.42 vs. 1.27 ± 1.89; moderate: 7.08 ± 4.08 vs. 3.54 ± 3.77; major: 0.56 ± 0.74 vs. 0.37 ± 0.77) and 2.63 ± 1.08 vs. 2.19 ± 1.42 (p = 0.0457), respectively. Conclusions: Polypharmacy should be an area of serious concern also in type 2 diabetes mellitus, especially in the elderly. In our study, type 2 diabetes mellitus patients received more drugs than their non-diabetes counterparts and were exposed to more drug-drug and food-drug interactions.

Sign in / Sign up

Export Citation Format

Share Document