scholarly journals Pseudo-Chilblains in a COVID-19 Patient

2021 ◽  
Author(s):  
Ricardo Moutinho-Guilherme ◽  
Gisela Bessa
Keyword(s):  
Skin Rash ◽  
Complete Resolution ◽  
Symptomatic Treatment ◽  
Clinical Suspicion ◽  
Burning Sensation ◽  
Cutaneous Manifestations ◽  
Local Burning

The aim of this case is to describe an example of cutaneous manifestations caused by COVID-19 infection, helping to better understand the disease and support an early clinical suspicion. This case addresses a 36-year-old patient with COVID-19 infection, symptomatic, with mild complaints. Seven days after the start of the clinic, she exhibited dermatological lesions in the acral areas bilaterally on her hands. The presence of erythematous-violet papules/vesicles was found in the dorsal extensor zones of the fingers, with local inflammatory signs, skin rash, flushing, edema, local burning sensation, itching and pain. Pseudo-chilblains were assumed as diagnostic hypotheses. She underwent symptomatic treatment, having achieved complete resolution at 10 days, with no subsequent sequelae.Attention should be paid to the fact that COVID-19 may present only with cutaneous manifestations, therefore these may serve as an indicator of the disease in suspected cases.

scholarly journals Staphylococcal scalded skin syndrome: A pediatric dermatology case report

2018 ◽  
Vol 6 ◽  
pp. 2050313X1775089 ◽  
Author(s):  
Girish Gulab Meshram ◽  
Neeraj Kaur ◽  
Kanwaljeet Singh Hura
Keyword(s):  
Complete Resolution ◽  
Skin Lesions ◽  
Clinical Suspicion ◽  
The Body ◽  
Intravenous Fluids ◽  
Effective Management ◽  
Pediatric Dermatology ◽  
Staphylococcal Scalded Skin Syndrome ◽  
High Clinical Suspicion ◽  
Hygiene Measures

Staphylococcal scalded skin syndrome is a condition which predominantly affects children and causes a spectrum of skin lesions. We present a case of a 2-month-old infant with complaints of fever and fragile blisters over the body. The mucosal areas were spared. The diagnosis of staphylococcal scalded skin syndrome was reached on clinical grounds and culture report. The patient responded well to the treatment, which included an antibiotic (cloxacillin), an analgesic (paracetamol), and hydration with intravenous fluids. He was discharged after 8 days, with almost complete resolution of his skin lesions. Having a high clinical suspicion for staphylococcal scalded skin syndrome, early diagnosis/treatment, and following robust hygiene measures are imperative for the effective management of staphylococcal scalded skin syndrome. More efforts are needed to develop novel therapies for staphylococcal scalded skin syndrome.

scholarly journals Cutaneous manifestations in COVID ‐19: A skin rash in a child

2020 ◽  
Vol 33 (6) ◽  
Author(s):  
Olga Yu Olisova ◽  
Ekaterina M. Anpilogova ◽  
Lidiya M. Shnakhova
Keyword(s):  
Skin Rash ◽  
Cutaneous Manifestations

scholarly journals Cutaneous Manifestations of Toxoplasmosis: a Case Report

2014 ◽  
Vol 6 (3) ◽  
pp. 113-119 ◽  
Author(s):  
Sonya Marina ◽  
Valja Broshtilova ◽  
Ivo Botev ◽  
Dimitrina Guleva ◽  
Maria Hadzhiivancheva ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Toxoplasma Gondii ◽  
Complete Resolution ◽  
Skin Lesions ◽  
The Body ◽  
Chemiluminescence Immunoassay ◽  
Cutaneous Manifestations ◽  
Blood Eosinophilia ◽  
The World

Abstract Although toxoplasmosis is one of the most widely spread infections in the world, types that involve the skin are extremely rare. However, skin lesions are not specific; moreover, they are quite diverse, which makes the diagnosis of cutaneous toxoplasmosis rather difficult. Thus, differential diagnosis should include a number of other diseases. We present a case of a 43-year-old immunocompetent man with multiple livid erythematous papules and nodules with yellowish discharge that involved the skin of the body and the extremities. By using electro-chemiluminescence immunoassay, immunoglobulin G antibodies to Toxoplasma gondii were detected in the serum, confirming the diagnosis of toxoplasmosis. The treatment with pyrimethamine and trimethoprim-sulfamethoxazole led to complete resolution of skin lesions. In conclusion, although rare in the dermatological practice, cutaneous toxoplasmosis should be considered in all patients presenting with lymphadenopathy, non-specific skin eruptions, especially nodular and colliquative, blood eosinophilia and histological findigs revealing abundant eosinophilic inflitrations.

Childhood Arthritis and Rheumatology Research Alliance Consensus Clinical Treatment Plans for Juvenile Dermatomyositis with Persistent Skin Rash

2016 ◽  
Vol 44 (1) ◽  
pp. 110-116 ◽  
Author(s):  
Adam M. Huber ◽  
Susan Kim ◽  
Ann M. Reed ◽  
Ruy Carrasco ◽  
Brian M. Feldman ◽  
...  
Keyword(s):  
Skin Rash ◽  
Complete Resolution ◽  
Juvenile Dermatomyositis ◽  
Clinical Treatment ◽  
Muscle Disease ◽  
Nominal Group ◽  
Rheumatology Research ◽  
Childhood Arthritis ◽  
Treatment Plans ◽  
Research Alliance

Objective.Juvenile dermatomyositis (JDM) is the most common form of idiopathic inflammatory myopathy in children. While outcomes are generally thought to be good, persistence of skin rash is a common problem. The goal of this study was to describe the development of clinical treatment plans (CTP) for children with JDM characterized by persistent skin rash despite complete resolution of muscle involvement.Methods.The Childhood Arthritis and Rheumatology Research Alliance, a North American consortium of pediatric rheumatologists and other healthcare providers, used a combination of Delphi surveys and nominal group consensus meetings to develop CTP that reflected consensus on typical treatments for patients with JDM with persistent skin rash.Results.Consensus was reached on patient characteristics and outcome assessment. Patients should have previously received corticosteroids and methotrexate (MTX). Three consensus treatment plans were developed. Plan A added intravenous immunoglobulin (IVIG) if it was not already being used. Plan B added mycophenolate mofetil, while Plan C added cyclosporine. Continuation of previous treatments, including corticosteroids, MTX, and IVIG, was permitted in plans B and C.Conclusion.Three consensus CTP were developed for use in children with JDM and persistent skin rash despite complete resolution of muscle disease. These CTP reflect typical treatment approaches and are not to be considered treatment recommendations or standard of care. Using prospective data collection and statistical methods to account for nonrandom treatment assignment, it is expected that these CTP will be used to allow treatment comparisons, and ultimately determine the best treatment for these patients.

Factors Correlating Outcome in Young Infants with Congenital Muscular Torticollis

2016 ◽  
Vol 67 (1) ◽  
pp. 82-87 ◽  
Author(s):  
Ji Hwa Ryu ◽  
Dong Wook Kim ◽  
Seung Ho Kim ◽  
Hyun Seok Jung ◽  
Hye Jung Choo ◽  
...  
Keyword(s):  
Complete Resolution ◽  
Clinical Suspicion ◽  
Thickness Ratio ◽  
Clinical Factors ◽  
Congenital Muscular Torticollis ◽  
Factors Associated ◽  
Young Infants ◽  
Visible Lesion ◽  
Muscular Torticollis

Purpose No previous study using follow-up ultrasonography for evaluating the factors associated with the successful regression of congenital muscular torticollis in young infants has been published. This study aimed to assess clinical factors and sonographic features potentially influencing regression in patients with congenital muscular torticollis. Methods From January 2010 to December 2012, 80 infants underwent neck ultrasonography because of clinical suspicion of congenital muscular torticollis. We statistically analysed the correlation between complete resolution and clinicosonographic findings when complete resolution was defined as no visible lesion on follow-up ultrasonography. Results Of the 80 infants, 61 had congenital muscular torticollis and all were followed up by ultrasonography: 1) 34 underwent physiotherapy, and 27 of them (79.4%) revealed complete resolution in follow-up; 2) 27 did not undergo physiotherapy, and 15 of them (55.6%) showed complete resolution. A statistically significant correlation was found between physiotherapy and complete resolution, but not between complete resolution and patient sex; size, volume, and echogenicity of the lesion; and thickness ratio. Conclusions Physiotherapy was the only factor influencing complete resolution in young infants with congenital muscular torticollis.

Switching cholinesterase inhibitors in older adults with dementia

2010 ◽  
Vol 23 (3) ◽  
pp. 372-378 ◽  
Author(s):  
Fadi Massoud ◽  
Julie Eve Desmarais ◽  
Serge Gauthier
Keyword(s):  
Complete Resolution ◽  
Cholinesterase Inhibitors ◽  
Symptomatic Treatment ◽  
Mechanisms Of Action ◽  
Consensus Guidelines ◽  
Open Label ◽  
Loss Of Response ◽  
Number Of Patients ◽  
Pharmacokinetic Properties ◽  
Initial Agent

ABSTRACTBackground: Cholinesterase inhibitors (ChEIs) represent the mainstay of symptomatic treatment in Alzheimer's disease. Three medications belonging to this class are presently widely available. These agents differ in their individual mechanisms of action and pharmacokinetic properties. Switching ChEIs can be a reasonable option in cases of intolerance or lack of clinical benefit.Methods: A systematic literature search of switching ChEIs was conducted, and all studies specifically evaluating this issue were identified. Published consensus guidelines were also searched for recommendations on ChEI switching.Results: Eight clinical studies are summarized and discussed. All of these studies are open-label or retrospective and they cannot be readily compared because of heterogeneity in design, number of patients, agents used, and endpoints. Switching in most of these studies was done for both “lack of benefit” or “loss of response” after up to 29 months of treatment. Nevertheless, the majority of studies did not include individuals switched for lack of response after several years of treatment. Lack of satisfactory response or intolerance with the initial agent was not predictive of similar results with the second agent.Conclusions: In light of these findings, we propose the following practical approach to switching ChEIs: (1) in the case of intolerance, switching to a second agent should be done only after the complete resolution of side-effects following discontinuation of the initial agent; (2) in the case of lack of efficacy, switching can be done overnight, with a quicker titration scheme thereafter; (3) switching ChEIs is not recommended in individuals who show loss of benefit several years after initiation of treatment.

scholarly journals Spontaneous Drainage of Large Parapharyngeal Abscess

2021 ◽  
Vol 3 (6) ◽  
pp. 01-03
Author(s):  
Camilla Berkembrock
Keyword(s):  
Antibiotic Therapy ◽  
Ct Scan ◽  
Female Patient ◽  
Early Treatment ◽  
Complete Resolution ◽  
Clinical Suspicion ◽  
Parapharyngeal Abscess

The case of a 68-year-old female patient, without comorbidities, with a diagnosis of a large parapharyngeal abscess on the left, was reported by a neck CT scan, which evolved with spontaneous drainage and complete resolution of the peritonsillar bulging, completing the therapeutic plan with antibiotic therapy, without abscess recurrence. Clinical suspicion, associated with neck CT, is an indispensable item in the design of early treatment, in order to avoid complications.

scholarly journals Case of Cronkhite-Canada Syndrome

2020 ◽  
Author(s):  
Bhageerath Raj D. ◽  
B. Ramesh Kumar ◽  
Ankit Vijay Agarwal
Keyword(s):  
Quality Of Life ◽  
Weight Loss ◽  
Early Diagnosis ◽  
Supportive Care ◽  
Symptomatic Treatment ◽  
Morbidity And Mortality ◽  
Definitive Treatment ◽  
Cutaneous Manifestations

AbstractCronkhite–Canada syndrome is a nonhereditary syndrome. It is characterized by cutaneous manifestations and gastrointestinal (GI) polyps. Patients may also present with diarrhea and weight loss. Early diagnosis of disease is important to avoid morbidity and mortality. Definitive treatment is not available for Cronkhite–Canada syndrome but supportive care and symptomatic treatment will improve the symptoms and increase the quality of life.

scholarly journals Inferior petrosal sinus route microcatheterization study and embolization for primary orbital varix

2015 ◽  
Vol 22 (1) ◽  
pp. 108-115 ◽  
Author(s):  
Vivek Singh ◽  
RV Phadke ◽  
Alok Udiya ◽  
Gurucharan S Shetty ◽  
Kumudini Sharma ◽  
...  
Keyword(s):  
Complete Resolution ◽  
Venous Access ◽  
Clinical Suspicion ◽  
The Other ◽  
Inferior Petrosal Sinus ◽  
Digital Subtraction ◽  
Central Venous ◽  
Rare Lesion ◽  
Vascular Channels ◽  
Orbital Varix

Purpose Primary orbital varix is a rare lesion but difficult to treat. Our main aim was to demonstrate the varices and their central venous communication and to explore the feasibility of embolization of these lesions. Method In four patients with clinical suspicion of varix, in whom MRI showed retro-global vascular channels, microcatheter digital subtraction angiography (DSA) of the varices was performed using femoral venous access. Embolization was carried out in two patients. Results In all four patients orbital varices could be accessed with a microcatheter through inferior petrosal sinus and ophthalmic vein (superior or inferior) route. Microcatheter angiography showed opacification of varices and demonstrated their central venous communication. Two patients were treated with coil embolization. Complete resolution of symptoms was seen in one patient and partial relief in the other. Conclusion The study presents microcatheterization of orbital varices via the inferior petrosal sinus–cavernous sinus–ophthalmic vein route with injections into distal ophthalmic veins for demonstration of these variceal sacs and their central venous connection. Coiling to disconnect the venous communication should be the primary goal of embolization.

scholarly journals A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus

2020 ◽  
Vol 12 (2) ◽  
pp. 155-158 ◽  
Author(s):  
Claudio Marasca ◽  
Angelo Ruggiero ◽  
Gabriella Fabbrocini ◽  
Matteo Megna
Keyword(s):  
Histological Examination ◽  
Skin Rash ◽  
Outpatient Clinic ◽  
Complete Resolution ◽  
Low Dose ◽  
Unknown Etiology ◽  
Topical Tacrolimus ◽  
Associated Symptoms ◽  
Dose Oral ◽  
The Face

Eosinophilic pustular folliculitis (EPF) (Ofuji disease) is a chronic, noninfectious pruritic cutaneous disorder of unknown etiology. No official guidelines are available for its treatment. Herein we present the case of a 59-year-old Caucasian man admitted to our outpatient clinic due to a generalized itchy skin rash characterized by papulo-pustules involving the face, trunk, and limbs. Histological examination supported the clinical diagnosis of EPF (Ofuji disease). The combination of low-dose oral indomethacin and topical tacrolimus ointment once a day led to a complete resolution of the lesions as well as associated symptoms in 8 weeks.

Sign in / Sign up

Export Citation Format

Share Document