scholarly journals THE AFFECTIONS OF JOINTS MORE HAPPENED IN IRAQI PURE BRED ARAB HORSES

2021 ◽  
Vol 26 (1) ◽  
pp. 118-125
Author(s):  
Sinan A. AL-Khazraji
Keyword(s):  
Body Weight ◽  
Clinical Examination ◽  
Standing Position ◽  
The Other ◽  
Whole Body ◽  
Hip Joints ◽  
Hind Limbs

This report was designed to study to affection of joints of the Iraqi Arabian horses limbs in vet. college clinic .The symmetrical in the size of joints and hooves in case of standing position . The clinical examination was done by palpation of fore and hind limbs from the sale of the hoof till the shoulder or hip joints. The results marked 68.35% of fetlock J.15.15% of coffin J.9.9%of hock J. and 6.6% of pastern joint. So it is means that the fetlock joint is more important than the other joints specially in fore limb e.i. one of the fore fetlock joints may lift the whole body weight .

Dorsoproximal proximal phalanx osteochondral fragmentation in 117 Warmblood horses

2009 ◽  
Vol 22 (01) ◽  
pp. 1-6 ◽  
Author(s):  
A. Martens ◽  
D. Maes ◽  
B. Boussauw ◽  
R. Forsyth ◽  
K. J. Boening ◽  
...  
Keyword(s):  
Clinical Examination ◽  
Hyaline Cartilage ◽  
Fibrous Tissue ◽  
Proximal Phalanx ◽  
The Other ◽  
Arthroscopic Evaluation ◽  
Hind Limbs ◽  
Mean Size ◽  
The Mean ◽  
Joint Evaluation

SummaryThe objective of the present study was to determine clinical and arthroscopic characteristics associated with dorso-proximal proximal phalanx (P1) fragments in Warmblood horses, as well as to examine their histopathological appearance. One hundred sixty-eight fragments were removed from 150 fetlocks of 117 Warmblood horses. Details of signalment and results of clinical examination were collected prior to surgery. After arthroscopic fragment removal and joint evaluation for synovial and/or cartilage abnormalities, the fragments were measured and evaluated histopathologically. The vast majority of the fragments (95.2%) were found medially, without predilection for front or hind limbs. In 10% of the joints, more than one fragment was present. The mean size of the fragments was 6.8 ± 2.6 mm. Only eight horses presented fetlock-related lameness. Horses of seven years of age and older (OR=13.32; p=0.033) and the presence of more than one fragment (OR=11.12; p=0.016) were significantly associated with lameness. Arthroscopic evaluation revealed one or more abnormalities in 50.7% of the joints. On histopathology, osteochondral fragments presented as a bony center covered with smooth hyaline cartilage on one side and some fibrous tissue on the other side. No clear histopathological signs were indicating precisely their origin. In Warmblood horses with dorsoproximal P1 fragments, the age (seven years and older) and the presence of more than one fragment in a fetlock significantly increased the risk of lameness. The osteochondral dorsoproximal P1 fragments could be defined as a developmental orthopaedic disease.

scholarly journals OR-054 A Comparative Study of Different Intervention Methods on Protein Expression of ERα in Uterus of Ovariectomized Osteoporosis Rats

2018 ◽  
Vol 1 (2) ◽  
Author(s):  
Shumin Bo
Keyword(s):  
Body Weight ◽  
Protein Expression ◽  
Western Blot ◽  
Lithium Chloride ◽  
Treadmill Exercise ◽  
Vertical Vibration ◽  
The Other ◽  
Whole Body ◽  
Genistein Treatment ◽  
Body Weight Dose

Objective The aim of this study was to compare the effects of different intervention methods on the protein expression of estrogen receptor alpha (ERα) in the uterus of ovariectomized osteoporosis rats. Methods Eighty healthy female SD rats, aged 3 months, were randomly divided into the following two groups by body weight: sham-operation (Sham) and ovariectomized (OVX). After ten weeks, the OVX groups were randomly divided into the following six groups by body weight: OVX; 17β-estradiol (E2); Genisteine (G); treadmill exercise (TE); Lithium chloride (Licl); Whole-body vertical vibration (WBVV). Then the rats was began to be treated with different intervention methods. The WBVV group rats were vibrated on a vibration platform twice per day for 7 weeks according to the following schedule: 90 hertz a minute and 15 minutes a time. The TE group rats were running on 5-uphill treadmills 45 minutes per day, 4 times a week, at a speed of 18 meters per minute. The G group rats were lavaged by genistein once per day according to body weight (dose 1mg/kg).The E2 group rats were treated with neck subcutaneous injection with 17β-E2 three times a week according to their body weight (dose 25ug/kg). At the end of 8 weeks intervention, during 36-48 hours, took blood from the abdominal aorta, and extracted the protein. The proteinexpression of ERα in uterus was detected by western blot. Results After OVX, the uterus weight index and serum E2 was significantly decreased. Both the uterus weight index and the serum E2 level were significantly increased after treatment with E2. However, no significant differences were seen after treatment with the other four methods. As revealed by the western blot results, the protein expression of ERα in the OVX groups was significantly higher than that of in the Sham group. After treatment with E2, treadmill exercise, whole-body vertical vibration, and lithium chloride, the protein expression of ERα was significantly lower than that of in OVX group. However, the genistein treatment had no significant difference.  Conclusions Apart from genistein treatment, the other four interventions had inhibitive effects on the protein expression of ERα in uterus of OVX osteoporosis rats.

scholarly journals Relationship between body conformation & fittness of racing horses

1999 ◽  
Vol 23 (1) ◽  
pp. 93-112
Author(s):  
S. A. Al-Khazragii ◽  
N. M. Jawad
Keyword(s):  
Analysis Of Variance ◽  
Clinical Examination ◽  
Management Training ◽  
Standing Position ◽  
Anatomical Structures ◽  
Shoulder Joints ◽  
Hind Limbs ◽  
Body Conformation ◽  
The Difference ◽  
Age And Sex

This study was designed to investgate - The Conformation and its effect on The Performance of the Arabian horses, aged (4-6) years in Iraq“. This research was perfomed in different regions for 193 horses. The age and sex of the horses were fixed. The anatomical structures were noticed. The symmetrical in size of joints and hooves in case of standing position, normal walk, trotter and the running were observed. The clinical examination was done by the palpation of fore limbs from the shoulder joints till the sole of the hoof. The examination of the hind limbs was performed also from the hip jointtill the sole The conformation measurements were recorded on 188 Arabic horses which were classified into two principle. The first class includes the racing horses while the classes . Second class was not sharing the races. The horses with aquired abnormal conformations were also registed. The analysis of variance (A.N.O.V.A) in between different groups revealed significant differences of P < 0.05,P<0.001  This significant differences was done to the difference in age, six, management, training and environment. Further more, the results of this study detected that the conformation measurements of Arabic horses in Iraq conceded with the measurements registed by other researchers. 

Radioimmunszintigraphie mit SPECT: Methodik, Probleme und klinische Erfahrungen

1987 ◽  
Vol 26 (05) ◽  
pp. 202-205 ◽  
Author(s):  
J. Fass ◽  
S. Truong ◽  
U. Büll ◽  
V. Schumpelick ◽  
R. Bares
Keyword(s):  
Clinical Practice ◽  
The Other ◽  
Whole Body ◽  
Blood Clearance ◽  
Planar Scintigraphy ◽  
Gastrointestinal Carcinomas ◽  
Body Regions ◽  
Other Hand ◽  
Body Retention ◽  
Klinische Erfahrungen

Radioimmunoscintigraphy (RIS) with 111ln- and 131 I-labelled monoclonal anti bodies (MAbs) against CEA and/or CA 19-9 was performed in 83 patients with various gastrointestinal carcinomas. A total of 276 body regions could be examined. The results of planar scintigraphy and SPECT were compared intraindividually. Using 111 In-labelled MAbs the sensitivity of RIS was significantly improved by SPECT (88.9 vs. 52.4% with planar scintigraphy, p <0.01). For131 l-labelled MAbs the effect was smaller (83.9 vs. 65.6% with planar scintigraphy, n.s.). This finding can be explained by different kinetics and biodistribution of the used MAb preparations.111 In-labelled MAbs with long whole-body retention and rapid blood clearance reveal ideal qualities for SPECT; on the other hand, the short whole-body retention of131 l-labelled MAbs leads to small count rates and therefore long counting times that make delayed SPECT unsuitable in clinical practice

Evaluation of a New Preparation of Urokinase

1973 ◽  
Vol 30 (01) ◽  
pp. 114-122
Author(s):  
C.R.M Prentice ◽  
K.M Rogers ◽  
G.P McNicol
Keyword(s):  
Body Weight ◽  
Maintenance Therapy ◽  
Initial Dose ◽  
Fibrinolytic Activity ◽  
Pharmacological Effect ◽  
Whole Body ◽  
Fibrinolytic Agent ◽  
Thromboplastic Activity

SummaryThe pharmacological effect of a new preparation of urokinase (Leo) has been studied, both in vitro and in six patients suffering from thrombo-embolic disorders. It was a non-toxic, effective fibrinolytic agent if given in sufficient dosage. A regimen consisting of an initial dose of 7,200 ploug units per kg body weight, followed by hourly maintenance therapy with 3,600 ploug units per kg intravenously, gave satisfactory evidence of whole body fibrinolytic activity. The preparation had minor but insignificant thromboplastic activity both when assayed in the laboratory and when given to patients.

Turnover and Distribution of 131Iodine-Labelled Human Fibrinogen

1964 ◽  
Vol 11 (02) ◽  
pp. 404-422 ◽  
Author(s):  
Annemarie Amris ◽  
C. J Amris
Keyword(s):  
Body Weight ◽  
Cancer Patient ◽  
Distribution Ratio ◽  
Half Life ◽  
Fibrinolytic Activity ◽  
The Other ◽  
Turnover Rates ◽  
Human Fibrinogen ◽  
Coagulation Defects ◽  
Fractional Turnover

Summary14 patients (5 diabetics with arteriosclerotic complications, 4 patients with thrombo-embolic disease, 4 with cirrhosis, coagulation defects and increased fibrinolytic activity, and 1 cancer patient) and 3 control patients were subjected to turnover studies with 13iodine labelled human fibrinogen.Half-life times in the control patients were found to be 4 days, the fractional turnover rates 19–23 per cent, of intravascular fibrinogen per day, and the absolute turnover 0.02 to 0.06 gm per day per kg. body weight. The other patient’s half-life times and turnover rates varied considerably from 0.9–5.5 days, 13–160 per cent, per day of intravascular fibrinogen and 0.02–0.4 gm per day per kg. body weight respectively.As fibrinogen unlike other proteins subjected to turnover studies, is converted to fibrin, it is not possible to measure the true intra-extravascular distribution ratio of fibrinogen. But intravascular fibrinogen could be approximated to constitute 68–99 per cent, of the total fibrinogen. There is justification in believing that fibrinogen is degradated through a continuous coagulation in equilibrium with fibrinolysis, and that the organism contains a greater mass of fibrin, the “fibrin pool”. Considerations of the turnover mechanism can however only be hypothetical.

scholarly journals Dental pulp stem cells overexpressing hepatocyte growth factor facilitate the repair of DSS-induced ulcerative colitis

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Ning Li ◽  
Yichi Zhang ◽  
Narayan Nepal ◽  
Guoqing Li ◽  
Ningning Yang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Ulcerative Colitis ◽  
Body Weight ◽  
Stem Cell ◽  
Dental Pulp ◽  
The Other ◽  
Therapeutic Effects ◽  
Colon Injury ◽  
Treatment Groups ◽  
Hepatocyte Growth

Abstract Background Ulcerative colitis (UC) is a chronic and recurrent disease without satisfactory treatment strategies. Dental pulp stem cell (DPSC) transplantation has been proposed as a potential therapy for UC. This study aimed to investigate the therapeutic effects of the rat hepatocyte growth factor (HGF) gene transduced into DPSCs for UC. Methods The therapeutic effects of HGF-DPSCs transplanted intravenously into a rat model of UC induced by 5% dextran sulphate sodium (DSS) were compared with the other treatment groups (LV-HGF group, DPSCs group and GFP-DPSCs group). Immunofluorescence and immunohistochemistry were used to observe the localization and proliferation of HGF-DPSCs at the site of colon injury. The expression levels of inflammatory factors were detected by real-time quantitative PCR (RT-PCR) and western blotting. The oxidative stress markers were detected by ELISA. DAI scores and body weight changes were used to macroscopically evaluate the treatment of rats in each group. Results Immunofluorescence and immunohistochemistry assays showed that HGF-DPSCs homed to colon injury sites and colocalized with intestinal stem cell (ISC) markers (Bmi1, Musashi1 and Sox9) and significantly promoted protein expression (Bmi1, Musashi1, Sox9 and PCNA). Anti-inflammatory cytokine (TGF-β and IL-10) expression was the highest in the HGF-DPSCs group compared with the other treatment groups, while the expression of pro-inflammatory cytokines (TNF-α and INF-γ) was the lowest. Additionally, the oxidative stress response results showed that malondialdehyde (MDA) and myeloperoxidase (MPO) expression decreased while superoxide dismutase (SOD) expression increased, especially in the HGF-DPSCs group. The DAI scores showed a downward trend with time in the five treatment groups, whereas body weight increased, and the changes were most prominent in the HGF-DPSCs group. Conclusions The study indicated that HGF-DPSCs can alleviate injuries to the intestinal mucosa by transdifferentiating into ISC-like cells, promoting ISC-like cell proliferation, suppressing inflammatory responses and reducing oxidative stress damage, which provides new ideas for the clinical treatment of UC.

scholarly journals Evaluation of whole-body modalities for diagnosis of multifocal osteonecrosis—a pilot study

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Shunichi Yokota ◽  
Keita Sakamoto ◽  
Yukie Shimizu ◽  
Tsuyoshi Asano ◽  
Daisuke Takahashi ◽  
...  
Keyword(s):  
Study Data ◽  
Whole Body ◽  
Hematologic Disease ◽  
Hip Joints ◽  
Patient Demographics ◽  
Examination Time ◽  
History Of ◽  
Body Magnetic Resonance Imaging ◽  
The Cost ◽  
Body Bone

Abstract Background This study aimed to investigate the ability of whole-body bone scintigraphy (WB-BS) in the detection of multifocal osteonecrosis (ON) compared to whole-body magnetic resonance imaging (WB-MRI) and to clarify the characteristics of patients with multifocal ON among those with ON of the femoral head (ONFH) using WB-MRI. Methods Forty-six patients who had symptomatic ONFH and underwent surgery in our hospital from April 2019 to October 2020 were included in the study. Data on patient demographics, including age, sex, body mass index (BMI), history of corticosteroid intake, alcohol abuse, smoking, and symptomatic joints, were collected from their medical records. All patients underwent WB-MRI and WB-BS before surgery. Results The agreement in the detection of ON by WB-MRI vs the uptake lesions by WB-BS in the hip joints was moderate (κ = 0.584), while that in other joints was low (κ < 0.40). Among the 152 joints with ON detected by WB-MRI, 92 joints (60.5%) were symptomatic, and 60 joints (39.5%) were asymptomatic. Twelve out of the 46 (26.0%) patients had multifocal (three or more distinct anatomical sites) ON. Nonetheless, while WB-BS detected symptomatic ON detected by WB-MRI as uptake lesions in 82.6% (76/92) of the joints, asymptomatic ON detected by WB-MRI was detected as uptake lesions in 21.7% (13/60) of the joints. All patients with multifocal ON had a history of steroid therapy, which was significantly higher than that in patients with oligofocal ON (P = 0.035). The patients with a hematologic disease had multifocal ON at a higher rate (P = 0.015). Conclusions It might be difficult for WB-BS to detect the asymptomatic ON detected by WB-MRI compared to symptomatic ON. Considering the cost, examination time, and radiation exposure, WB-MRI might be useful for evaluating multifocal ON. Larger longitudinal studies evaluating the benefits of WB-MRI for detecting the risk factors for multifocal ON are required.

scholarly journals Effect of Dietary Fat Composition and 2’Fucosyllactose on Neonatal Piglet Growth and Organ Lipid Composition

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1038-1038
Author(s):  
Michael Miklus ◽  
Pedro Prieto ◽  
Cynthia Barber ◽  
Robert Rhoads ◽  
Samer El-Kadi
Keyword(s):  
Fatty Acids ◽  
Body Weight ◽  
Fatty Acid ◽  
Body Weight Gain ◽  
Dietary Fatty Acids ◽  
The Body ◽  
The Other ◽  
Human Infant ◽  
Lps Challenge ◽  
Group 3

Abstract Objectives The objectives of this study were to determine the effect of 2’fucosyllactose (2’FL) and fat blends on growth, body composition and fatty acid profile of the liver and brain using the neonatal pig as a model for the human infant. Methods Pigs (3 d old) were randomly assigned to either: 1. control, 2. Palm Olein (PO) fat blend – Low 2'-FL, 3. PO – High 2'-FL, 4. High oleic acid (HO) – Low 2'-FL, 5. HO FB – High 2'-FL, 6. PO FB – GLA, or 7. kept with their sows. Pigs in groups 1 to 6 received 250 ml·kg−1·d−1 of formula in 5 equal meals for 15 d. On day 14 of the study, groups 1–6 received intraperitoneal E. coli LPS challenge at 100 µg·kg−1 weight. Results Body weight was greater for piglets fed by sows than those in the other groups (P &lt; 0.001). In addition, % fat and bone mineral content were higher in the sow-fed group while lean % was less sow-fed piglets (group 7) compared with those in the other groups (P &lt; 0.05). Only longissimus weight expressed as a % of body weight, was greater for group 7 compared with all other groups (P &lt; 0.001). Soleus, semitendinosus, brain, heart and spleen weights as a % of body weight were similar across all groups. However, liver weight as a % of body weight was greater in groups 1–6 (3.7%) compared with group 7 (2.8%; P &lt; 0.001). The proportion of brain 16:1 fatty acid was less (0.83%) for groups 1–6 than for group 7 pigs (1.08%; P &lt; 0.0001). The proportion of 20:3 N6 was greatest (0.66%) for group 3 compared with groups 1 and 4 (0.55%; P &lt; 0.05). In addition, the proportion of 20:5 N3 was greatest (0.12%) for group 3 compared with groups 1 and 7 (0.07%; P &lt; 0.05). The proportion of liver 16:1, 18:0, and 18:1 cis-11 fatty acids were greater for group 7 (2.3, 23, 2.2%) than groups 1–6 (0.2, 20, 1.2%; P &lt; 0.0001). Conversely, the contribution of 14:0, 18:1 cis-9, 18:3 N6 cis-6,9,12, and 22:6 N3 were greater for pigs in groups 1–6 (1.3, 0.6, and 14, 7.8%) compared with those in group 7 (0.5, 8.5, 0.2 and 3.5%; P &lt; 0.0001). Conclusions Our data suggest that feeding 2’fucosyllactose had no effect on the body weight gain and composition in neonatal pigs. Our data also suggest that dietary fatty acids have a greater effect on liver than on brain fatty acid composition. Funding Sources Funding for the work was provided by Perrigo Nutritionals, LLC.

scholarly journals Correction of congenital deformity of hind limbs of cat by femoro-tarsal arthrodesis: a case report

2008 ◽  
Vol 53 (No. 8) ◽  
pp. 452-455 ◽  
Author(s):  
J. Park ◽  
K.R. Cho ◽  
B.C. Sutradhar ◽  
D. Chang ◽  
S.H. Choi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Congenital Deformity ◽  
Hip Joints ◽  
Hind Limbs ◽  
Satisfactory Outcome

Congenitally deformed tibia-fibulas of both hind limbs were diagnosed in a four-month-old, female, domestic shorthair cat that was unable to bear weight and whose movement was painful on both stifle and hock joints. Bleeding was observed repeatedly from the wound made by deformed tibias at the cranial sides of hock joints where the bones were exposed. Radiography and computed tomography revealed a corn-shaped tibia and bow shaped fibula which extended cranio-distally without formation of the hock joints. Femoro-tarsal arthrodesis was successfully executed on both hind legs after exclusion of the deformed and pliable tibia-fibulas. Follow-up radiography showed that bone fusions had gradually improved and were without complications. Postoperatively, the cat was capable of walking on the corrected hind legs and running on the movement of hip joints. To the authors’ knowledge, this is the 1st reported case of femoro-tarsal arthrodesis in a cat. In this case, femoro-tarsal arthrodesis resulted in a satisfactory outcome for congenitally deformed tibia-fibulas in cat.

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