scholarly journals Phyllodic tumors of the breast: Frequency and anatomo-histoclinical aspects at Conakry University Teaching Hospital (CHU). Guinea

2021 ◽  
Vol 2 (1) ◽  
pp. 001-006
Author(s):  
Boubacar siddi Diallo ◽  
Boubacar alpha Diallo ◽  
Ibrahima conte ◽  
Abdoulaye sylla ◽  
Diallo yaya ◽  
...  

Objectives: Calculate the frequency of phyllodes tumors of the breast, describe the epidemiological profile and describe the anatomo-histoclinical aspects of phyllodes tumors of the breast at the Conakry University Teaching Hospital. Methodology: This was a retrospective descriptive type study lasting 10 years, from January 1, 2008 to December 31, 2018. It concerned all cases of breast lesions, the parts that were examined in the anatomo-pathological laboratory. All cases of mammary tumours were included for the diagnosis of phyllodes tumor which was histologically confirmed. All cases of breast lesions for which the diagnosis was histologically ruled out were excluded. We carried out an exhaustive examination of the data available in the registers of the anatomo-pathologies service of the Conakry University Teaching Hospital. . The limitations or constraints of the study were the absence of certain information on the pathological examination request forms and the absence of an immunohistochemical study. Results: The frequency of phyllodes tumors was 02.72% (n = 22) among benign and malignant breast pathologies (n = 807) and 1.65% among those of genital and breast pathologies (n = 1334). The epidemiologic profile was that of a woman in the age group 50-59 (27.27%), nulliparous (45.45%). Inflammation was the main reason for consultation (100%). The main presumptive clinical diagnosis was benign tumor (54.54%). Lumpectomy was the main surgical procedure (36.36%) followed by excised biopsies (27.27%). Cases of phyllodes with a consistency firm were the most observed (50%) followed by cases with associated consistency 6 cases (27.27%). Phyllodes tumours without rearrangements represented (63.63%) followed by cases with associated rearrangements (13.63%). Grade I constituted the majority of the histological grade found (54.54%) followed by grade II (22.73%). Phyllodes tumors with benign behavior constituted the majority of cases observed 17 (77.27%). Tumors resected in a healthy zone were the most represented (72.73%). The histologic types with good prognosis constituted the majority of our diagnosed cases (77.27%). Conclusion: Phyllodes tumours constitute of a particular histological type of fibroepithelial tumours of the breast. They constitute a predominantly benign tumor, its malignant forms consist of high-grade sarcomas, often with a poor prognosis. They affect all ages, but especially women between the third and fifth decade. Their diagnosis is exclusively histological, which makes it possible to assess to their behavior, grade and histological prognosis

2021 ◽  
Vol 19 (1) ◽  
pp. 19-25
Author(s):  
Pravin Prasad ◽  
Anish Mudvari ◽  
Rakesh Ghimire ◽  
Naresh Karki ◽  
Dipendra Yadav ◽  
...  

Background: Drug promotional literatures can often be misleading and have biased information and can contribute to irrational use of medicines. Thus, it is necessary that prescribers critically analyze the drug promotional literatures presented to them. This study attempts to understand if the prescribers at Tribhuvan University Teaching Hospital are aware about the necessary information that should be present in a drug promotional literature.Methods: A descriptive cross-sectional study was conducted over six months in which prescribers at Tribhuvan University Teaching Hospital were provided with the self-administered questionnaire and were requested to submit the filled in questionnaire. Prescribers presently working at Tribhuvan University Teaching Hospital, attending out patient department services and had received drug promotional literatures within last six months were included in this study. Results: During the study, 163 of the received questionnaires met the inclusion criteria and were utilized for analysis. Advertisement, reminder items and others type of drug promotional literatures were commonly received by prescribers included in our study. Higher proportion of faculties (35.29%) preferred reprint type of drug promotional literatures. Most of the participants (47.85%) searched for 5-8 WHO-Ethical Criteria for Medicinal Drug Promotion criteria when referring a drug promotional literature. It was seen that 42.94% of prescribers realised that at least two out of four types of information related to negative attribute of the promoted medicines were missing.Conclusions: The prescribers with least duration of clinical exposure are more likely to always prescribe the medicines promoted to them. Prescribers were more confident on claims made in drug promotional literatures if they were supported using scientific evidences.Keywords: Drug promotional literatures; prescriber perception;WHO-ECMDP


2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 37s-37s
Author(s):  
O. Oluwole

Background: The incidence of prostate cancer (Pca) is the first in malignant tumors among men in the United States, and mortality rate is the second cause of deaths. Incidental prostate cancer is defined as clinically inapparent tumor that is neither palpable nor visible by imaging. Incidental carcinoma is found in 3%-16% of pathology specimens of patients undergoing BPH surgery and it involves less than 5% of resected tissue. Aim: To identify incidentally detected prostate cancer in benign prostatic specimens submitted for histopathology Methods: This is a ten-year retrospective histopathology study of all prostate cancer cases diagnosed between 1991-2000 in the department of Pathology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria. Haematoxylin & eosin stained histology slides were retrieved and studied. Institution review board (IRB) approval was obtained from the Teaching Hospital to undertake this study. Results: A total of 67 patients had benign prostatic hyperplasia; the patients' age ranged from 30-75 years with a mean age of 52.5 years. The peak age at diagnosis was in the fifth decade. 26 (38.8%) patients had incidental carcinoma. All the tumors were adenocarcinoma and moderately differentiated. Two patients in their fourth decade were found to have incidental prostate cancer. Conclusion: Incidental prostate cancer is common in patients' undergoing radical prostatectomy for BPH, a high index of suspicion, adequate histopathology training and histopathologic evaluation is critical to diagnosis.


2014 ◽  
Vol 9 (2) ◽  
pp. 22-26
Author(s):  
B R Bhandari ◽  
R Jha ◽  
J Baral ◽  
R R Wagle

Aims: This study was done to assess the use of family planning method among comprehensive abortion care clients in Tribhuvan University Teaching Hospital (TUTH).   Methods: A hospital based observational study was conducted in family planning clinic at TUTH from 14th April 2009 to 14th June 2010 among one hundred clients who opted for comprehensive abortion care (CAC) at the hospital CAC centre and met the inclusion criteria of this study.   Results: Around 98% women had knowledge of different types of modern contraceptive methods. Majority of CAC clients (91%) had ever used contraceptive methods in the past. Injectables were the most common method of contraceptive used by the CAC clients (55%). Almost 22% clients had come for repeat induced abortion. About 43% clients opted CAC service for complete family and 33% for contraceptive failure. Withdrawal method failure was seen in 17% of clients. Almost 86% women intend to use contraceptive after CAC service in future.   Conclusions: This study concluded that despite knowledge of modern contraceptive methods and ever uses of different family planning methods, majority of clients had no consistency in use of various contraceptives. Effective family planning counseling along with information of emergency contraceptive is required for each CAC clients to prevent unwanted pregnancy and abortion.DOI: http://dx.doi.org/10.3126/njog.v9i2.11740


2021 ◽  
Vol 4 (1) ◽  
pp. 433-438
Author(s):  
Samiksha Niroula ◽  
Rama Subba ◽  
Aarem Karkee

Introduction: Dyslipidemia is a risk factor for coronary artery disease, a leading cause of mortality in patients with type 2 diabetes mellitus. This study aims to study the dietary pattern and dyslipidemia of type 2 diabetes mellitus patients visiting Tribhuvan University Teaching Hospital. Materials and Methods: Quantitative study was done to find out the dietary pattern and dyslipidemia of type 2 diabetes mellitus patients visiting Tribhuvan University Teaching Hospital. Patients with type 2 diabetes mellitus diagnosed for more than one year were included in the study. Results: The percentage of dyslipidemia in type 2 diabetes mellitus was found to be 88.5%. Dyslipidemia was found to be significantly associated (p<0.05) with alcohol consumption, regular dietary management, sedentary behavior, waist-hip ratio, body mass index, glycated hemoglobin, and hypertension. Dyslipidemia was also found to be significantly associated (p<0.05)  with the dietary habit (vegetarian and non-vegetarian), consumption of cereals and its product, consumption of fruits, consumption of fast foods and street foods, consumption of red meat, and consumption of oilseeds. Conclusions: This study indicates the importance of dietary awareness and lifestyle modification for the management of dyslipidemia among type 2 diabetes mellitus.


2015 ◽  
Author(s):  
Mohamed Ahmed ◽  
Michael Jeffers ◽  
John Feeney ◽  
Pardeep Govender ◽  
Mark Sherlock ◽  
...  

2015 ◽  
Author(s):  
Mohamed Ahmed ◽  
Michael Jeffers ◽  
John Feeney ◽  
Pardeep Govender ◽  
Mark Sherlock ◽  
...  

Author(s):  
Olajide Tayo Emmanuel ◽  
Adetunji Oluseye Adetayo ◽  
Ope-Babadele Oluwatosin Oyindamola ◽  
Ojo Eunice Abimbola ◽  
Salawu Rasidi Akinade

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