Covid-19 and food security: Jeopardy management and posterity deliberations

COVID-19, also known as the ‘novel coronavirus disease 2019’, is a respiratory illness and the causative pathogen is officially named as ‘SARS-CoV-2’. Infections with SARS-CoV-2 have now been amplified to a global pandemic – as of April 3, 2020, nearly 1,018,000 cases have been confirmed in more than 195 countries, including more than 300,000 cases within the United States. Public safety guidelines are followed worldwide to stop the spread of COVID-19 and stay healthy. Despite COVID-19 is a respiratory illness with mode of invasion through the respiratory tract, not the gastrointestinal tract, an average food consumer is anxious and concerned about the food safety. Could an individual catch the deadly contagious COVID-19 from groceries brought home from the supermarket – or from the next restaurant takeout order? This brief review elucidates the epidemiology and pathobiological mechanism(s) of SARS-CoV-2 and its implications in food-borne infections, transmission via food surfaces, food processing and food handling.

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The Role of Glucocorticoids in the Management of COVID-19

Hormone and Metabolic Research ◽

10.1055/a-1300-2550 ◽

2020 ◽

Vol 53 (01) ◽

pp. 9-15

Author(s):

Vasileia Ismini Alexaki ◽

Holger Henneicke

Keyword(s):

Inflammatory Diseases ◽

Respiratory Illness ◽

The Novel ◽

Diverse Range ◽

Global Pandemic ◽

Frontline Treatment ◽

Systemic Glucocorticoids ◽

Emerging Issues ◽

Life Threatening ◽

Novel Coronavirus

AbstractCoronavirus disease 2019 (COVID-19), caused by an infection with the novel coronavirus SARS-CoV-2, has resulted in a global pandemic and poses an emergency to public health systems worldwide. COVID-19 is highly infectious and is characterized by an acute respiratory illness that varies from mild flu-like symptoms to the life-threatening acute respiratory distress syndrome (ARDS). As such, there is an urgent need for the development of new therapeutic strategies, which combat the high mortality in severely ill COVID-19 patients. Glucocorticoids are a frontline treatment for a diverse range of inflammatory diseases. Due to their immunosuppressive functions, the use of glucocorticoids in the treatment of COVID-19 patients was initially regarded with caution. However, recent studies concluded that the initiation of systemic glucocorticoids in patients suffering from severe and critical COVID-19 is associated with lower mortality. Herein we review the anti-inflammatory effects of glucocorticoids and discuss emerging issues in their clinical use in the context of COVID-19.

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Pediatric Emergency Department Responses to COVID-19: Transitioning From Surge Preparation to Regional Support

Disaster Medicine and Public Health Preparedness ◽

10.1017/dmp.2020.197 ◽

2020 ◽

pp. 1-7

Author(s):

Emily A. Hartford ◽

Ashley Keilman ◽

Hiromi Yoshida ◽

Russell Migita ◽

Todd Chang ◽

...

Keyword(s):

United States ◽

Emergency Department ◽

Pediatric Patients ◽

The United States ◽

Pediatric Emergency ◽

Pediatric Emergency Department ◽

The Novel ◽

Global Pandemic ◽

The World ◽

Novel Coronavirus

ABSTRACT In the midst of a global pandemic, hospitals around the world are working to meet the demand for patients ill with the 2019 coronavirus disease (COVID-19) caused by the novel coronavirus first identified in Wuhan, China. As the crisis unfolds, several countries have reported lower numbers as well as less morbidity and mortality for pediatric patients. Thus, pediatric centers find themselves pivoting from preparing for a patient surge to finding ways to support the regional response for adults. This study describes the response from 2 West Coast freestanding academic children’s hospitals that were among the first cities in the United States impacted during this pandemic.

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Treatment for the Transmission of Coronavirus Disease 2019 from Human to Human by Hand as Divine Creators Code 19

Journal of Biomedical Engineering and Medical Imaging ◽

10.14738/jbemi.74.8702 ◽

2020 ◽

Vol 7 (4) ◽

pp. 16-31

Author(s):

Mohammad Abul Hossain

Keyword(s):

Respiratory Illness ◽

Dose Schedule ◽

The United States ◽

Human Hand ◽

Global Pandemic ◽

The World ◽

One Year ◽

Novel Coronavirus ◽

The Third World ◽

Third World War

On 11 February 2020, the WHO declared the Coronavirus disease 2019 (COVID-19) as a new pandemic defined as the illness caused by a novel coronavirus now called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which was first identified amid an outbreak of respiratory illness cases in Wuhan City, Hubei Province, China. It has not been previously identified in humans but WHO mentioned the virus, SARS-CoV-2 is transmitted from human to human by hand. The COVID-19 has been spreading rapidly across the world, affecting more than 185 countries. Up to 11 May 2020, over four million people are infected and over one fourth of million individuals around the world have died from the COVID-19. Till now, there is no approved medicine to prevent COVID-19 infection. WHO said, it is one year away to receive COVID-19 vaccine. The above panic situation and global pandemic insists me to consider, it is the Third World War of Divine Creator, Allah by Bio-weapon due to Human’s recent activity against the Creator such as modification of the Holy Qur’an, insulting the Prophet Muhammad (peace be upon him), etc. This paper presents the evidence of the involvement of Divine Creator in this pandemic, and the transmission of COVID-19 by human hand is simulated with the Divine Creator’s Code “19”. Based on the simulation, a probable treatment process is proposed to immediate relief of mankind from COVID-19. Again, evaluated by Divine Creator’s Code 19, it is suggested that the vaccine mRNA-1273, developed at the biotechnology company Moderna in Massachusetts, could be applicable (2-dose schedule at Day 57) to prevent infection with SARS-CoV-2 causes the disease COVID-19 but it is taking time for testing of safe and effectiveness which is going on in the National Institute of Allergy and Infectious Diseases Research Center in the United States of America.

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SARS-CoV-2 and COVID-19: From the Bench to the Bedside

Physiological Reviews ◽

10.1152/physrev.00020.2020 ◽

2020 ◽

Vol 100 (4) ◽

pp. 1455-1466 ◽

Cited By ~ 17

Author(s):

Stefano Romagnoli ◽

Adriano Peris ◽

A. Raffaele De Gaudio ◽

Pierangelo Geppetti

Keyword(s):

Disease Progression ◽

Respiratory Illness ◽

The United States ◽

Current Treatment ◽

Clinical Syndrome ◽

The Novel ◽

Treatment Uncertainties ◽

Novel Coronavirus ◽

Pulmonary Microcirculation ◽

Degrees Of Severity

First isolated in China in early 2020, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the novel coronavirus responsible for the ongoing pandemic of Coronavirus Disease 2019 (COVID-19). The disease has been spreading rapidly across the globe, with the largest burden falling on China, Europe, and the United States. COVID-19 is a new clinical syndrome, characterized by respiratory symptoms with varying degrees of severity, from mild upper respiratory illness to severe interstitial pneumonia and acute respiratory distress syndrome, aggravated by thrombosis in the pulmonary microcirculation. Three main phases of disease progression have been proposed for COVID-19: an early infection phase, a pulmonary phase, and a hyperinflammation phase. Although current understanding of COVID-19 treatment is mainly derived from small uncontrolled trials that are affected by a number of biases, strong background noise, and a litany of confounding factors, emerging awareness suggests that drugs currently used to treat COVID-19 (antiviral drugs, antimalarial drugs, immunomodulators, anticoagulants, and antibodies) should be evaluated in relation to the pathophysiology of disease progression. Drawing upon the dramatic experiences taking place in Italy and around the world, here we review the changes in the evolution of the disease and focus on current treatment uncertainties and promising new therapies.

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The Most Widely Disseminated COVID-19-Related Scientific Publications in Online Media: A Bibliometric Analysis of the Top 100 Articles with the Highest Altmetric Attention Scores

Healthcare ◽

10.3390/healthcare9020239 ◽

2021 ◽

Vol 9 (2) ◽

pp. 239

Author(s):

Ji Yoon Moon ◽

Dae Young Yoon ◽

Ji Hyun Hong ◽

Kyoung Ja Lim ◽

Sora Baek ◽

...

Keyword(s):

Clinical Manifestations ◽

The United States ◽

Online Media ◽

The Novel ◽

Scientific Publications ◽

Document Type ◽

Search Terms ◽

Global Pandemic ◽

Publication Language ◽

Novel Coronavirus

The novel coronavirus disease 2019 (COVID-19) is a global pandemic. This study’s aim was to identify and characterize the top 100 COVID-19-related scientific publications, which had received the highest Altmetric Attention Scores (AASs). Hence, we searched Altmetric Explorer using search terms such as “COVID” or “COVID-19” or “Coronavirus” or “SARS-CoV-2” or “nCoV” and then selected the top 100 articles with the highest AASs. For each article identified, we extracted the following information: the overall AAS, publishing journal, journal impact factor (IF), date of publication, language, country of origin, document type, main topic, and accessibility. The top 100 articles most frequently were published in journals with high (>10.0) IF (n = 67), were published between March and July 2020 (n = 67), were written in English (n = 100), originated in the United States (n = 45), were original articles (n = 59), dealt with treatment and clinical manifestations (n = 33), and had open access (n = 98). Our study provides important information pertaining to the dissemination of scientific knowledge about COVID-19 in online media.

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Fear of An Unprecedented, Invisible Enemy: Difficulties Experienced In Establishing Criteria For The Release of COVID-19 Patients From Isolation

10.21203/rs.3.rs-571466/v1 ◽

2021 ◽

Author(s):

Hideharu Hagiya ◽

Kou Hasegawa ◽

Fumio Otsuka

Keyword(s):

The United States ◽

University Hospital ◽

The Novel ◽

Emerging Infections ◽

General Management ◽

Global Pandemic ◽

Level Of Understanding ◽

Novel Coronavirus ◽

Discharge Protocol ◽

Common Understanding

Abstract Introduction: The novel coronavirus disease 2019 (COVID-19) has emerged as a global pandemic, and the United States and European authorities established criteria for the release of COVID-19 patients from isolation in October 2020. However, a huge discrepancy exists between the hospital-discharge protocol for COVID-19 patients and the release of patients from in-hospital isolation. Our initially proposed criteria for in-hospital release from isolation was not adhered to by healthcare workers (HCWs) due to prevailing concerns regarding disease infectivity. Herein, we report difficulties encountered in attempting to establish a common understanding of the management of emerging infections. Methods: We performed a Google Form-based questionnaire survey targeting HCWs from Okayama University Hospital, Japan, via e-mail on January 21–28, 2021. The anonymous investigation required respondents to provide information regarding their background as well as perceptions regarding the requirement, level of understanding, and readiness for developing release criteria.Results: We obtained 150 eligible responses, including 57 (38.0%) from medical doctors and 53 (35.3%) from nurses. Most HCWs managing COVID-19 patients advocated for the implementation of the criteria, whereas those not working in that capacity did not (p<0.001). Over half of the HCWs indicated discomfort at seeing COVID-19 patients transitioning to general management even after meeting the criteria. Conclusions: It was challenging to establish a common understanding regarding the ideal criteria for in-hospital release of COVID-19 patients from isolation in our hospital. The dissemination of our experiences and multifaceted discussions with HCWs would be of great value as a countermeasure against the emergent pandemic.

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Universities and COVID-19 Growth at the Start of the 2020 Academic Year

10.1101/2020.11.25.20238899 ◽

2020 ◽

Author(s):

Mike Penuliar ◽

Candice Clark ◽

Debbie Curti ◽

Cathy Hudson ◽

Billy Philips

Keyword(s):

Research University ◽

The United States ◽

The Novel ◽

Global Pandemic ◽

Public Research University ◽

Epidemiological Tool ◽

Texas Tech University ◽

Novel Coronavirus ◽

The Impact ◽

Academic Year

The global pandemic of 2020 caused by the novel coronavirus of 2019 (COVID-19) has uprooted the education system of the United States. As American colleges and universities try to resume regular instruction for the 2020-2021 academic year, outbreaks have begun to emerge and university towns across the country are now virus hotspots. The current paper provides two studies. First, the current work investigates how the growth of COVID-19 compares in areas with large universities against those without. Results showed markedly increase case growth in counties with large universities at the start of the fall 2020 semester. Secondly, this work provides a highly accessible and modifiable epidemiological tool known as a susceptible-infected-removed model for educational administrators that will allow users to see the impact of COVID-19 historically and predictively. The results of an exemplar model using a large public research university, Texas Tech University, are discussed.

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Synthetic and semi-synthetic drugs as promising therapeutic option for the treatment of COVID-19

Mini-Reviews in Medicinal Chemistry ◽

10.2174/1389557520666201204162103 ◽

2020 ◽

Vol 20 ◽

Author(s):

Ekta Shirbhate ◽

Preeti Patel ◽

Vijay K Patel ◽

Ravichandran Veerasamy ◽

Prabodh C Sharma ◽

...

Keyword(s):

Therapeutic Option ◽

Antiviral Treatment ◽

The Novel ◽

Clinical Experiences ◽

Synthetic Compounds ◽

Synthetic Drugs ◽

Global Pandemic ◽

The World ◽

Novel Coronavirus

: The novel coronavirus disease-19 (COVID-19), a global pandemic that emerged from Wuhan, China has today travelled all around the world, so far 216 countries or territories with 21,732,472 people infected and 770,866 deaths globally (as per WHO COVID-19 update dated August 18, 2020). Continuous efforts are being made to repurpose the existing drugs and develop vaccines for combating this infection. Despite, to date, no certified antiviral treatment or vaccine prevails. Although, few candidates have displayed their efficacy in in vitro studies and are being repurposed for COVID-19 treatment. This article summarizes synthetic and semi-synthetic compounds displaying potent activity in their clinical experiences or studies against COVID-19 and also focuses on mode of action of drugs being repositioned against COVID-19.

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Belonging in the Coronaverse: Will There Be Time?

Open Anthropological Research ◽

10.1515/opan-2020-0107 ◽

2021 ◽

Vol 1 (1) ◽

pp. 100-115

Author(s):

Kate Fischer ◽

Malika Rakhmonova ◽

Mike Tran

Keyword(s):

College Experience ◽

The United States ◽

Limited Time ◽

The Novel ◽

Residential University ◽

To Come ◽

Novel Coronavirus ◽

University Experience ◽

The U.S ◽

Older Siblings

Abstract Since the spring of 2020 SARS-CoV-2, the novel coronavirus, has upended lives and caused a rethinking of nearly all social behaviors in the United States. This paper examines the ways in which the pandemic, shutdown, and gradual move towards “normal” have laid bare and obfuscated societal pressures regarding running out of time as it pertains to the residential university experience. Promised by movies, television, and older siblings and friends as a limited-time offer, the “typical” college experience is baked into the U.S. imaginary, reinforcing a host of notions of who “belongs” on campus along lines of race, class, and age. Fed a vision of what their whole lives “should be”, students who enter a residential four-year college are already imbued with a nostalgia for what is yet to come, hailed, in Althusser’s (2006[1977]) sense, as university subjects even before their first class. The upheaval of that subjecthood during the pandemic has raised important questions about the purpose of the college experience as well as how to belong to a place that is no longer there.

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FEATURES OF THE COURSE AND TACTICS OF MANAGING CHILDREN WITH KIDNEYS AND URINARY TRACT DISEASES DURING THE PANDEMIC OF NEW CORONAVIRUS INFECTION COVID-19

PEDIATRIA Journal named after G N SPERANSKY ◽

10.24110/0031-403x-2021-100-4-74-79 ◽

2021 ◽

Vol 100 (4) ◽

pp. 74-79

Author(s):

I.M. Kagantsov ◽

◽

V.V. Sizonov ◽

V.G. Svarich ◽

K.P. Piskunov ◽

...

Keyword(s):

Age Groups ◽

Clinical Manifestations ◽

Routine Care ◽

The Novel ◽

Urinary System ◽

Death Rates ◽

Global Pandemic ◽

Coronavirus Infection ◽

Novel Coronavirus ◽

Significant Health

The novel coronavirus infection (SARS-CoV-2), which first appeared in Wuhan, China in December 2019, has been declared a global pandemic by WHO. COVID-19 affects people of all age groups. The disease in children is usually asymptomatic or mild compared to adults, and with a significantly lower death rates. Data on kidney damage in children with COVID-19, as well as the effect of coronavirus infection on the course of diseases of the genitourinary system, are limited, the risks of contracting a new coronavirus infection in children with significant health problems, including those with chronic kidney disease, remain uncertain. The pandemic has affected the activities of surgeons treating diseases of the urinary system in children. Since the prospects for the end of the pandemic are vague, it is necessary to formulate criteria for selecting patients who can and should be provided with routine care in the pandemic. The purpose of this review is to highlight the features of the clinical manifestations and treatment of children with COVID-19, occurring against the background of previous renal pathology or complicating its course.

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