FEATURES OF THE COURSE AND TACTICS OF MANAGING CHILDREN WITH KIDNEYS AND URINARY TRACT DISEASES DURING THE PANDEMIC OF NEW CORONAVIRUS INFECTION COVID-19

2021 ◽  
Vol 100 (4) ◽  
pp. 74-79
Author(s):  
I.M. Kagantsov ◽  
◽  
V.V. Sizonov ◽  
V.G. Svarich ◽  
K.P. Piskunov ◽  
...  
Keyword(s):  
Age Groups ◽  
Clinical Manifestations ◽  
Routine Care ◽  
The Novel ◽  
Urinary System ◽  
Death Rates ◽  
Global Pandemic ◽  
Coronavirus Infection ◽  
Novel Coronavirus ◽  
Significant Health

The novel coronavirus infection (SARS-CoV-2), which first appeared in Wuhan, China in December 2019, has been declared a global pandemic by WHO. COVID-19 affects people of all age groups. The disease in children is usually asymptomatic or mild compared to adults, and with a significantly lower death rates. Data on kidney damage in children with COVID-19, as well as the effect of coronavirus infection on the course of diseases of the genitourinary system, are limited, the risks of contracting a new coronavirus infection in children with significant health problems, including those with chronic kidney disease, remain uncertain. The pandemic has affected the activities of surgeons treating diseases of the urinary system in children. Since the prospects for the end of the pandemic are vague, it is necessary to formulate criteria for selecting patients who can and should be provided with routine care in the pandemic. The purpose of this review is to highlight the features of the clinical manifestations and treatment of children with COVID-19, occurring against the background of previous renal pathology or complicating its course.

scholarly journals Prevention and treatment system of novel coronavirus infection in medical and health institutions: experience in West China Hospital of Sichuan University

2020 ◽  
Vol 37 (10) ◽  
pp. 639-641
Author(s):  
Qiao Zhou ◽  
He Yu ◽  
Zong-An Liang ◽  
Rong Yao ◽  
Feng-Ming Luo ◽  
...  
Keyword(s):  
Treatment System ◽  
The Novel ◽  
West China Hospital ◽  
West China ◽  
Global Pandemic ◽  
Prevention And Treatment ◽  
Coronavirus Infection ◽  
Health Institutions ◽  
Novel Coronavirus

The novel coronavirus infection broke out in Wuhan, China, in December 2019, and progressed to a global pandemic. We describe the measures taken by West China Hospital of Sichuan University to address the diagnosis, prevention and treatment of the infection.

scholarly journals Nepal’s Response to Contain COVID-19 Infection

2020 ◽  
Vol 18 (1) ◽  
pp. 128-134 ◽  
Author(s):  
Rano Mal Piryani ◽  
Suneel Piryani ◽  
Jay Narayan Shah
Keyword(s):  
Regional Cooperation ◽  
Initial Response ◽  
The Novel ◽  
Comprehensive Plan ◽  
Imported Case ◽  
Global Pandemic ◽  
Before And After ◽  
Global Status ◽  
Coronavirus Infection ◽  
Novel Coronavirus

Nepal is a landlocked country bordering two most populous countries, India and China. Nepal shares open border with India from three sides, east, south and west. And, in north with China, where the novel coronavirus infection (CVOVID-19) began in late December 2019. The first confirmed imported case in Nepal was reported in 2nd week of January 2020. The initial response of Nepal to COVID-19 were comparably slow but country geared efforts after it was declared a ‘global pandemic’ by WHO on 11 March, 2020. Government of Nepal’s steps from 18 March, 2020 led to partial lock down and countrywide lockdown imposed on 24 March, 2020. Government devised comprehensive plan on 27 March, 2020 for quarantine for peoples who arrived in Nepal from COVID-19 affected countries. This article covers summary of global status, South Asian Association of Regional Cooperation (SAARC) status, and Nepal’s response to contain COVID-19 infection discussed under three headings: Steps taken before and after WHO declared COVID-19 a global pandemic and lab services regarding detection of COVID-19. Nepal has documented five confirmed cases of COVID-19 till the end of March 2020, first in second week of 15 January, 2020 and 2nd case 8-weeks thereafter and 3rd case two days later, 4th on 27 March and 5th on 28 March. Four more cases detected during first week of April. Non-Pharmacological interventions like social distancing and excellent personal habits are widely practiced. Country has to enhance testing and strengthen tracing, isolation and quarantine mechanism and care of COVID-19 patients as Nepal is in risk zone because of comparably weak health system and porous borders with India. The time will tell regarding further outbreak and how it will be tackled.Keywords: COVID-19; lockdown; Nepal; pandemic; response

scholarly journals THE STRUCTURE OF EXCESS MORTALITY DUE TO THE NOVEL CORONAVIRUS INFECTION PANDEMIC IN URBAN AND RURAL RESIDENTS

2021 ◽  
Vol 67 (5) ◽  
pp. 1
Author(s):  
T.P. Sabgayda ◽  
◽  
Keyword(s):  
Rural Areas ◽  
Excess Mortality ◽  
Age Groups ◽  
The Novel ◽  
Rural Residents ◽  
Urban And Rural Residents ◽  
Coronavirus Infection ◽  
The Russian Federation ◽  
Direct Loss ◽  
Novel Coronavirus

Significance. The pandemic of the novel coronavirus infection has further exacerbated the demographic problem in the Russian Federation, which was especially acute in rural areas. However, according to official data, only one third of the excess mortality in 2020 is accounted for by COVID-19. Purpose: to compare the structure of mortality growth in urban and rural residents and determine differences in loss associated with the COVID-19 pandemic. Material and methods. Based on the Rosstat preliminary data, the author has analyzed increase in the number of deaths per 100,000 population in 2020 compared to 2019 among males and females residing in urban and rural areas of the Russian Federation. The indicators were compared by major classes of death causes and individual diseases across the following three age groups: 15-49 years, 50-64 years, and 65 years and older. Comparison was carried out by the Chi-square test. Results. Among the urban and rural population the death rate increased by 20.6% and 15.4%, respectively; the COVID-19 mortality equaled to 109.4 and 67.5 per 100,000 population; the share of COVID-19 in the increased total mortality added up to 44.6% and 33.0%, respectively. Among urban residents, the frequency of deaths from COVID-19 in males exceeds the female one 1.8 times in population aged 15-49, 2.0 times in population aged 50-64 and 65 +; among rural residents, these values equal to 1.2, 1.4 and 1.8, respectively. Conclusion. In the structure of excess mortality associated with the spread of the novel coronavirus infection that accounted for almost one fifth of deaths in 2019, the share of direct loss due to COVID-19 is underestimated. The direct loss associated with co-infection with SARS-CoV-2 virus can be traced at the population level, starting from the age of 65 in males and 50 years in females, in case of deaths from diseases of the nervous system, coronary heart disease, chronic diseases of the lower respiratory tract and diseases of the pancreas. With a lower level of excess mortality among rural population, its quarter is accounted for by indirect loss due to the pandemic associated with the decreased access to medical care. In the structure of excess mortality among urban population, indirect loss accounts for about one tenth, and is mainly due to consequences of stress associated with the pandemic and forced isolation. Signs of incomplete examination of the deceased in older age groups to determine the death causes, especially among rural residents, have been identified.

scholarly journals Role of nutrients regulation in the immune system in preventing COVID-19 infection: A brief review

2021 ◽  
Vol 13 (2) ◽  
pp. 760-765
Author(s):  
Anamika Chauhan
Keyword(s):  
Immune System ◽  
Age Groups ◽  
World Health ◽  
The Novel ◽  
Beneficial Effects ◽  
Coronavirus Infection ◽  
The Common ◽  
Novel Coronavirus ◽  
Health Organization

This review aimed to focus on using foods to boost immunity against COVID-19 in all age groups. In human, coronavirus causes the common cold, severe acute respiratory syndrome (SARS), and a major threat to public health. The novel coronavirus was declared a pandemic by the World Health Organization due to its rapid infectivity. COVID-19 infection is most probably reported in people with low immunity response. The nutrients, which show beneficial effects on the immune system, are called immune nutrients and diet is called immune diet. A healthy diet can reduce the risk of infection of COVID-19 and can prevent disease. Nutritional food intake is also necessary for people with chronic illness, obese persons, diabetes, cardiovascular disease, cognitive dysfunction like anxiety and depression. All nutrients are essential for maintaining immunity and providing appropriate amounts of protein, fat, carbohydrate, vitamins, and minerals for the surveillance mode of keeping us from getting sick. The use of plenty of water, minerals such as micronutrients, zinc, copper, selenium, iron, magnesium, food rich in vitamins, and a good lifestyle can promote health and overwhelm this coronavirus infection.

scholarly journals Practices in Handling Clinical Samples in a COVID-19 Laboratory - An Experience from Chennai, India

2021 ◽  
Vol 10 (39) ◽  
pp. 3508-3510
Author(s):  
Saramma Mini Jacob ◽  
Kanagasabai Sivasangeetha ◽  
Durairaj Anitha ◽  
Singaram Kaplana
Keyword(s):  
Wide Spectrum ◽  
Clinical Manifestations ◽  
Gastrointestinal Symptoms ◽  
World Health ◽  
Clinical Samples ◽  
The Novel ◽  
Global Pandemic ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Respiratory Droplets

In early January 2020, China had started raising concerns of a new contagious disease caused by new strains of coronavirus, Severe Acute Respiratory SyndromeCoronavirus-2 (SARS-CoV-2). The World Health Organization (WHO) on March 11, 2020, had declared the novel coronavirus (COVID-19) outbreak a global pandemic. COVID-19 was transmitted from person to person through respiratory droplets generated when an infected person coughs, sneezes, breathing or through contact with a surface that has been contaminated 1 and through aerosols-airborne microdroplets.2 The clinical manifestations of COVID-19 represents a wide spectrum of disease ranging from mild to severe respiratory syndrome influenza-like illness with mainly lower respiratory tract symptoms, complicated by pneumonia and Acute Respiratory Distress Syndrome (ARDS), high fever, and headache. In many cases, loss of taste and smell and severe gastrointestinal symptoms were reported, as are cardiac problems, with the latter being perhaps secondary to a cytokine storm such as is seen in the more severely affected patients. 3 WHO COVID-19 dashboard on June 25th 2021 showed 179, 686, 071 confirmed cases worldwide.

scholarly journals Diagnosis and treatment of acute coronary syndrome during the novel coronavirus infection COVID-19 pandemic

2020 ◽  
Vol 25 (4) ◽  
pp. 3854
Author(s):  
A. M. Namitokov ◽  
O. P. Ishevskaya ◽  
V. I. Fetisova ◽  
E. D. Kosmacheva ◽  
V. A. Porkhanov
Keyword(s):  
Acute Coronary Syndrome ◽  
Clinical Manifestations ◽  
The Novel ◽  
Therapeutic Approaches ◽  
Susceptible Population ◽  
Coronary Syndrome ◽  
Cardiovascular Patients ◽  
Coronavirus Infection ◽  
Artery Disease ◽  
Novel Coronavirus

The novel coronavirus infection COVID-19 pandemic has spread to more than 180 countries. Cardiovascular patients belong to one of the susceptible population cohorts. There is a peculiar pathogenesis and variety of clinical manifestations of COVID-19, as well as difficulties with early diagnosis. Other unresolved issues are routing, surgery and therapy of such patients and comorbidities. Due to absence of well-defined algorithms and guidelines, the treatment of patients with acute coronary syndrome (ACS) in different countries is carried out differently. Interactions between antiviral and coronary artery disease medications are also not completely clear. Based on the available data, the main organizational and therapeutic approaches for ACS during the COVID-19 pandemic are reflected.

Analysis of the clinical manifestations of cerebral stroke in patients with the novel coronavirus infection (COVID-19)

2020 ◽  
pp. 30-45
Author(s):  
Vladislav V. Andreev ◽  
Alexander Y. Podunov ◽  
Daniil S. Lapin ◽  
Zarema L. Gilyaeva ◽  
Ekaterina N. Nikiforova ◽  
...  
Keyword(s):  
Lung Tissue ◽  
Hemorrhagic Stroke ◽  
Clinical Laboratory ◽  
Clinical Manifestations ◽  
Community Acquired Pneumonia ◽  
Control Group ◽  
Cerebral Stroke ◽  
The Novel ◽  
Coronavirus Infection ◽  
Novel Coronavirus

Objective: To improve the diagnosis and treatment of acute cerebrovascular accident in patients with community-acquired pneumonia caused by the novel coronavirus infection (COVID-19). Materials and methods: For the first time, clinical manifestations of strokes in patients with diagnosed new coronavirus infection (COVID-19) were analyzed in 130 patients. The study was conducted in two groups. The main group consisted of 69,2 % (n = 90) with a clinical and instrumental diagnosis: novel coronavirus infection in combination with stroke. The control group (30,8 %; n = 40) included the cases of ischemic and hemorrhagic stroke without signs of SARS-CoV-2. In both groups, the severity of the disease and pathogenetic subtypes were compared, and the features of the laboratory biochemical data were studied. Statistical analysis of the outcomes was carried out taking into account the severity of brain and lung tissue damage. Results: In patients with cerebral stroke against the background of the new coronavirus infection (COVID-19), the prevalence of ischemic stroke cases (86,4 %) was noted for undetermined (41,4 %) and cardioembolic (35,7 %) pathogenetic subtypes (according to TOAST) with localization in the carotid basin (89,7 %). In hemorrhagic stroke, parenchymal hemorrhage was observed with a greater frequency (54,5 %). The severity of the diagnosed strokes according to the NIHSS scale was up to 13,16 (8,80) points with less severe brain damage — Glasgow coma scale (14,0 (12,0 15,0). In the group of the patients, a widespread lesion of the lung tissue was diagnosed in 82,2 % of cases. No significant increase in the incidence of clinically significant manifestations of systemic and organ hypercoagulation was established. Conclusions: In stroke patients with COVID-19, ischemic manifestations with undetermined and cardioembolic subtypes without age and gender features prevail, with no differences in the severity of the course and a large number of favorable outcomes. A high activity of inflammatory and infectious changes was established by clinical laboratory.

Immune properties of lactoferrin and its protective role in new coronavirus infection COVID-19

2021 ◽  
pp. 22-26
Author(s):  
S. V. Orlova ◽  
E. A. Nikitina ◽  
E. V. Prokopenko ◽  
L. Yu. Volkova ◽  
A. N. Vodolazkaya
Keyword(s):  
Humoral Immunity ◽  
Acute Phase Protein ◽  
Clinical Manifestations ◽  
Protective Role ◽  
Viral Diseases ◽  
The Novel ◽  
Phase Protein ◽  
Nasal Secretions ◽  
Coronavirus Infection ◽  
Novel Coronavirus

Thousands of studies have been conducted to study the new SARS-CoV-2 coronavirus, its infectious properties, transmission routes and all associated with the clinical manifestations and severity of COVID-19, especially with potential treatments. Lactoferrin is a member of the transferrin family, which is synthesized by epithelial cells of mammalian internal glands and is widely present in various secretory fluids such as milk, saliva, tears, and nasal secretions. Lactoferrin is one of the components of the innate humoral immunity, regulates the functions of immunocompetent cells and is a acute phase protein. Lactoferrin has strong antioxidant and anti-inflammatory properties. This review assesses the possibility of using lactoferrin as a supplement in immunocorrective therapy programs for viral diseases, including the novel coronavirus infection COVID-19.

scholarly journals The Coronavirus Disease 2019 (COVID-19): A Review

2020 ◽  
pp. 1-9 ◽  
Author(s):  
Sheikh Salahuddin Ahmed
Keyword(s):  
Clinical Manifestations ◽  
Severe Illness ◽  
The Novel ◽  
Full Spectrum ◽  
Pcr Method ◽  
Coronavirus Infection ◽  
Novel Virus ◽  
Clinical Illness ◽  
Novel Coronavirus ◽  
Supportive Management

Many details of the emergence of 2019 novel coronavirus infection such as its origin, spread, epidemiology, full spectrum of clinical illness, treatment and mortality rate has not been clearly defined. This review focuses the epidemiological evidences, clinical manifestations, investigations and treatment provided to the admitted cases of the 2019 novel coronavirus pneumonia in various hospitals of Wuhan city and other regions in China. Information have been gathered mainly from relevant researches and papers that were published recently. Clinical manifestations included fever, non-productive cough, dyspnoea, myalgia, fatigue, radiographic manifestations of pneumonia and detection of the novel virus by RT-PCR method. Some patients rapidly developed acute respiratory distress syndrome, acute respiratory failure, and other serious complications with fatal outcomes. There are neither vaccines nor effective treatments for the disease caused by the virus, but efforts are typically confined to symptomatic and supportive management. Antivirals and corticosteroids were used in severe illness but had no effective outcome.

Sign in / Sign up

Export Citation Format

Share Document