scholarly journals A Critique of "Effect of 10 Weeks of High-Intensity Interval Training on Protein Levels of NF-kB and Expression of Atrogin-1 and MuRF-1 in Cardiomyocytes of Female Mice with Breast Cancer"

2021 ◽  
Vol 13 (4) ◽  
pp. 77-79
Author(s):  
Mojtaba Sepandi ◽  
Keyword(s):  
Breast Cancer ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
Female Mice ◽  
Protein Levels ◽  
High Intensity Interval

scholarly journals High Intensity Interval Training Increases Natural Killer Cell Number and Function in Obese Breast Cancer-challenged Mice and Obese Women

2017 ◽  
Vol 22 (4) ◽  
pp. 260-266 ◽  
Author(s):  
Nicole G. Barra ◽  
Isabella Y. Fan ◽  
Jenna B. Gillen ◽  
Marianne Chew ◽  
Katarina Marcinko ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Natural Killer Cell ◽  
High Intensity ◽  
Killer Cell ◽  
Interval Training ◽  
Cell Number ◽  
Obese Women ◽  
High Intensity Interval Training ◽  
High Intensity Interval ◽  
And Function

scholarly journals Interactive effect of 6 weeks of High-intensity interval training and quercetin supplementation on expression of some tumor angiogenesis markers in female mice with breast cancer

2021 ◽  
Vol 43 (1) ◽  
pp. 142-151
Author(s):  
Zohreh Jalali ◽  
Fereshteh Shahidi ◽  
abbas ali Gaeini ◽  
Shaban Alizadeh ◽  
Alireza Ramezani
Keyword(s):  
Breast Cancer ◽  
Tumor Angiogenesis ◽  
High Intensity ◽  
Breast Cancer Cells ◽  
Tumor Tissue ◽  
Statistical Tests ◽  
Interactive Effect ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
High Intensity Interval

Background: About angiogenesis, metastasis of breast cancer and exercise, Many studies have been done in recent decades to better understand of regulatory mechanisms. The purpose of this study was to investigate the Interactive effect of high-intensity interval training (HIIT) and quercetin supplementation (Q) on the expression of key angiogenic factors in tumor tissue of mouse with breast cancer. Methods: Twenty-four female Balb/C mouse were injected with estrogen receptor-dependent breast cancer cells MC4L2 and then divided into three groups of tumor (T), tumor + of high-intensity interval training (TH) and tumor + high-intensity interval training + quercetin (THQ). The TH and THQ groups ran the treadmill 3 days a week for 6 weeks and each session 1 hour. The THQ group received 110 mg / kg quercetin solution for 6 weeks, 3 days a week with training. After completion of the work, the mouse were sacrificed and their tumor tissue removed and frozen in liquid nitrogen And stored at -70 ° C. Expression of TIE-2 and VEGF-A genes was measured by REAL TIME-PCR. ΔCt, ΔΔCt, and Fold change were calculated with the relevant statistical tests at the significant level (P <0.05) by GENEX software. Results: The results showed that THQ interaction significantly decreased the expression of TIE-2 and VEGF-A genes in TH and THQ groups compared to T group. In addition, quercetin in THQ group significantly decreased TIE-2 and VEGF-A gene expression compared to TH group. Conclusion: interaction of HIIT and Q supplementation are probably effective in inhibiting tumor angiogenesis.

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