scholarly journals Effect of Single Clove Garlic Extract (Allium Sativum Linn) on Blood Sugar Levels, Malondialdehyde, Insulin Levels and Insulin Resistance (Experiments in Rats (Rattus Novergicus) Induced by Streptozotocin

2020 ◽  
Vol 9 (2) ◽  
pp. 954-963
Author(s):  
Yeni Susanti ◽  
Merryana Adriani ◽  
Annis Catur Adi

Oral antidiabetic drugs mostly give unwanted side effects, so it is necessary to develop a traditional treatment system for diabetes mellitus which is relatively safe. The purpose of this study was to determine the effect of single clove garlic on decreasing blood sugar levels, decreasing malondialdehyde levels, increasing insulin levels, and decreasing insulin resistance in experimental rats induced by streptozotocin 50 mg / KgBB. (P1) therapy of single clove garlic 50 mg/kgBB, (P2) therapy of single clove of garlic 75 mg/KgBB, (P3) therapy of single clove of garlic 125 mg/KgBB. The most effective dose in this study was 125 mg/KgBB. Comparison test the mean of each group with the Manova test. The flavonoids in single clove garlic have been shown to be powerful agents to reduce the pathogenesis of diabetes and its complications.

Author(s):  
Talib Mearza ◽  
Wesam Abou Amer ◽  
Maryam Al Jaber

Type II diabetes is caused by insulin resistance resulting in high blood sugar levels. Although the typical symptoms of diabetes are described as polyuria, polydipsia and fatigue as many as 60% of newly diagnosed patients with type II diabetes are asymptomatic. Here authors present a case of a 39-year-old male patient who presented with localized pruritus affecting the medial aspects of his forearms and upper legs as the sole symptom of newly diagnosed type II diabetes mellitus. The itch symptom markedly improved on significantly reducing his dietary intake of sugars and with the use of metformin. Authors hope to alert clinicians to consider the possibility of underlying diabetes in such presentations to enable swift diagnosis and consequent treatment. It is unusual to find patients presenting with localized itch without any corresponding cutaneous manifestations as a presentation of type II diabetes.


2021 ◽  
Vol 3 (1) ◽  
pp. 224-228
Author(s):  
Riski N. Situmeang ◽  
Erwin Sopacua

Diabetes Mellitus (DM) is a chronic disease characterized by blood glucose (blood sugar) levels exceeding normal. Diabetic nephropathy is a chronic microvascular complication that often occurs in diabetics. This study presents a picture of diabetic nephropathy in type 2 DM patients at the Royal Prima Hospital in Medan. This research is a type of descriptive research. The sample from this study was the total data of patients suffering from diabetic nephropathy who met the inclusion and exclusion criteria at Royal Prima Hospital from January 1, 2020 – to December 31, 2020. The inclusion criteria for the subjects of this study were complete patient medical records, type 2 diabetes patients, urinalysis tests. (proteinuria ≥ +2), renal function examination exceeds normal values, blood urea, and creatinine. The mean age of diabetic nephropathy patients was 57.52 years and the majority were 62 men (50.8%). The average picture of urea levels in diabetic nephropathy patients is 51.8 and the average creatinine level is 1.48. The majority of patients with diabetic nephropathy do not have proteinuria. And the average blood sugar level is 267 mg/dL. In conclusion, the incidence of diabetic nephropathy is highest in patients aged 57 years. The mean value of urea level is 51.80 mg/dl, creatinine value is 1.48 mg/dl, and the average blood sugar level is 267 mg/dl. Most proteinuria was in the negative category of as many as 107 people (87%).


2021 ◽  
Vol 14 (4) ◽  
pp. 35-41
Author(s):  
LILYA N. SHEIKHMAMBETOVA ◽  
◽  
SVETLANA N. EGOROVA ◽  
ELENA A. EGOROVA ◽  
ELVIRA YU. BEKIROVA ◽  
...  

Diabetes mellitus is one of the most significant social problems of public health. The main pathogenetic factors in the development of type 2 diabetes mellitus are a decrease in insulin synthesis by β­cells of Langerhans islets or impaired insulin receptor sensitivity to insulin, which leads to a high risk of insulin resistance and β­cell dysfunction.


2021 ◽  
Vol 11 (1) ◽  
pp. 146-150
Author(s):  
Udo Mfoniso E ◽  
Udofia Ukpong S ◽  
Mbah Patricia E

The main objective of this study was to determine the potency of meals prepared from breadfruit flour as a major source of carbohydrate in the management regime of type II diabetes mellitus. Ten (10) diabetic patients were involved in the study. After feeding the patients with cake, biscuits and puddings made from breadfruit flour as a major food ingredient, for a period of three days, the results showed that there was a significant reduction in the collective blood sugar levels of the patients. The mean blood sugar level of the patients was observed to drop from 20.19 mol/L to 18.75 mol/L. The glucose response curve revealed that diabetic patients who were fed with breadfruit flour meal showed positive post prandial effect as a result of reduced sugar level. In conclusion, the observation of the response glucose curve and glycemic index of breadfruit gives a supportive clue as to why breadfruit flour meals should be adopted in the menu list of diabetic patients as a control towards the management of diabetes mellitus conditions.


PEDIATRICS ◽  
1966 ◽  
Vol 37 (4) ◽  
pp. 597-604
Author(s):  
Doman K. Keele ◽  
Jacob L. Kay

Simultaneous plasma free fatty acid (FFA) and blood sugar levels were determined for fasting newborn infants during the first 24 hours of life, for their cord bloods, and for their mothers at delivery. The following observations were made. In control infants the mean FFA level rose about three times the cord level after birth and was accompanied by a 25% drop in the mean blood sugar level. Thereafter, the mean blood sugar level remained relatively constant, but the mean FFA level varied from 2½ to 3 times the cord level. There was no significant correlation between the length of maternal fasting prior to delivery and the infant FFA level; there was, however a significant negative correlation between the length of maternal fasting prior to delivery and the infant blood sugar level at 24 hours of age. High FFA levels occurred in the infants of obese mothers and low levels were observed in infants with delayed respirations, in infants of preeclamptic mothers, and in infants of diabetic mothers.


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