Magnesium Carbonate, Citric Acid, and Potassium Citrate for Oral Solution

2021 ◽  
Keyword(s):  
Citric Acid ◽  
Magnesium Carbonate ◽  
Potassium Citrate ◽  
Oral Solution

scholarly journals Successful Management of Refractory Type 1 Renal Tubular Acidosis with Amiloride

2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Patrick Oguejiofor ◽  
Robert Chow ◽  
Kenneth Yim ◽  
Bernard G. Jaar
Keyword(s):  
Citric Acid ◽  
Sodium Bicarbonate ◽  
Sjögren’S Syndrome ◽  
Muscle Pain ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Potassium Citrate ◽  
Sjögren‘S Syndrome

A 28-year-old female with history of hypothyroidism, Sjögren’s Syndrome, and Systemic Lupus Erythematosus (SLE) presented with complaints of severe generalized weakness, muscle pain, nausea, vomiting, and anorexia. Physical examination was unremarkable. Laboratory test showed hypokalemia at 1.6 mmol/l, nonanion metabolic acidosis with HCO3 of 11 mmol/l, random urine pH of 7.0, and urine anion gap of 8 mmol/l. CT scan of the abdomen revealed bilateral nephrocalcinosis. A diagnosis of type 1 RTA likely secondary to Sjögren’s Syndrome was made. She was started on citric acid potassium citrate with escalating dosages to a maximum dose of 60 mEq daily and potassium chloride over 5 years without significant improvement in serum K+ and HCO3 levels. She had multiple emergency room visits for persistent muscle pain, generalized weakness, and cardiac arrhythmias. Citric acid potassium citrate was then replaced with sodium bicarbonate at 15.5 mEq every 6 hours which was continued for 2 years without significant improvement in her symptoms and electrolytes. Amiloride 5 mg daily was added to her regimen as a potassium sparing treatment with dramatic improvement in her symptoms and electrolyte levels (as shown in the figures). Amiloride was increased to 10 mg daily and potassium supplementation was discontinued without affecting her electrolytes. Her sodium bicarbonate was weaned to 7.7 mEq daily.

Comparison of potassium citrate, citric acid and placebo on calcium phosphate stones recurrence: Preliminary results

2018 ◽  
Vol 17 (2) ◽  
pp. e439-e440
Author(s):  
S. Doizi ◽  
J. Poindexter ◽  
M. Pearle ◽  
K. Sakhaee ◽  
N. Maalouf
Keyword(s):  
Citric Acid ◽  
Calcium Phosphate ◽  
Potassium Citrate ◽  
Preliminary Results

scholarly journals A new spectrofluorimetric method for the determination of ascorbic acid with bromocresol purple in pharmaceutical samples

2021 ◽  
Vol 3 (11) ◽  
Author(s):  
L. Klepo ◽  
M. Ascalic ◽  
D. Medunjanin ◽  
A. Copra-Janicijevic
Keyword(s):  
Ascorbic Acid ◽  
Folic Acid ◽  
Citric Acid ◽  
Magnesium Carbonate ◽  
New Method ◽  
Bromocresol Purple ◽  
Pharmaceutical Samples ◽  
Spectrofluorimetric Method ◽  
Calcium And Magnesium

Abstract Based on the interaction between ascorbic acid and bromocresol purple, a new simple, straightforward, and quick method for the quantification of ascorbic acid is proposed. The procedure is based on the determined quenching effect of ascorbic acid on the natural fluorescence signal of bromocresol purple in the reaction between ascorbic acid and bromocresol purple in phosphate buffer solution (pH 6). The reduction of bromocresol purple fluorescence intensity is detected at 641 nm, while excitation occurs at 318 nm. The linear relationship between the reduced fluorescence intensity of bromocresol purple and the concentration of ascorbic acid is in the range 4.65 × 10–5 to 4.65 × 10–6 mol L−1 (R2 = 0.9964), with the detection limit of 8.77 × 10–7 mol L−1 and quantification limit of 2.35 × 10–5 mol L−1. The findings in this study further show that the new method provides good precision and repeatability, as well as satisfactory recovery values in terms of accuracy. The new method is tested on fifteen samples with different amounts of ascorbic acid and additional components. The effects of interfering components such as citrus bioflavonoids, citric acid, folic acid, paracetamol, calcium, and magnesium carbonate on the intensity of fluorescence of bromocresol purple are also investigated. The effects of interfering components such as citrus bioflavonoids (routine and hesperidin), citric acid, folic acid, paracetamol, calcium, and magnesium carbonate on the intensity of fluorescence of bromocresol purple are also investigated. The results of iodometric titration point out that the new method is effective for the determination of ascorbic acid in pharmaceutical samples. Article Highlights A new spectrofluorimetric method for determination of ascorbic acid in pharmaceutical samples using bromocresol purple. Determination of optimal parameters for ascorbic acid determination in a variety of pharmaceutical samples. Examination of the influence of additional substances in the pharmaceutical samples on the analysis.

Formation constants for magnesium and calcium citrate complexes

1980 ◽  
Vol 33 (7) ◽  
pp. 1511 ◽  
Author(s):  
KN Pearce
Keyword(s):  
Aqueous Solution ◽  
Citric Acid ◽  
Metal Ions ◽  
Formation Constants ◽  
Potassium Citrate ◽  
Divalent Metal ◽  
Calcium Citrate ◽  
Divalent Metal Ions ◽  
Citrate Complex

centration formation constants for magnesium and calcium citrate complexes have been redetermined from pH titrations of citric acid in the absence and presence of the divalent metal ions in aqueous solution at 2° Values for the constants, corrected for the presence of potassium citrate complex, are presented and critically compared with literature values. Values for the formation constants of strontium and barium citrate complexes are also reported.

Effects of Potassium Citrate/Citric Acid Intake in a Mouse Model of Polycystic Kidney Disease

Nephron ◽  
2000 ◽  
Vol 84 (3) ◽  
pp. 270-273 ◽  
Author(s):  
George A. Tanner ◽  
Kodi Vijayalakshmi ◽  
Judith A. Tanner
Keyword(s):  
Citric Acid ◽  
Kidney Disease ◽  
Mouse Model ◽  
Polycystic Kidney Disease ◽  
Potassium Citrate ◽  
Polycystic Kidney ◽  
Acid Intake
Sign in / Sign up

Export Citation Format

Share Document