scholarly journals Necrólise epidérmica tóxica associada ao lúpus eritematoso sistêmico: um relato de caso

2019 ◽  
Vol 82 (20) ◽  
Author(s):  
Maria Fernanda Palermo da Silva ◽  
Rosane de Paula Codá ◽  
Luis Augusto Carrera Louzada ◽  
Wânia de Oliveira Vianna ◽  
Ghislaine de Mattos Ferreira Faria ◽  
...  

Objetiva-se descrever o caso clínico de uma paciente com Necrólise Epidérmica Tóxica, tendo como enfoque oacompanhamento da evolução das lesões cutâneas; discutir o acompanhamento da evolução da doença e o uso dascoberturas disponíveis para a realização dos curativos; e analisar a eficácia do tratamento empregado com Polihexanidabetaina (PHMB) e placas de hidrofibra com prata. Trata-se de um relato de caso realizado em um hospital federal do estadodo Rio de Janeiro sob autorização por escrito da paciente. O curativo era realizado diariamente, pela Comissão Terapêuticade Feridas (CTF) e médicos da Cirurgia Plástica. No curativo do corpo, que apresentava áreas com descolamento total daepiderme e muito friáveis inicialmente foi utilizada como cobertura primária Sulfadiazina de prata a 1%. Conduta que foimantida por 07 dias, não havendo melhora aparente do quadro. Foi então realizada antissepsia com o PHMB e utilizadasplacas de hidrofibra em todo o corpo. Após 15 dias, na terceira troca do curativo, evidenciou-se melhora significativa, nãosendo necessário uso de hidrofibra. Concluí-se que ficou clara a eficácia do tratamento empregado e evidente a importânciado uso da cobertura adequada para cada demanda, sendo vantajoso e benéfico para todas as partes envolvidas.Palavras-chave: Doenças Autoimunes; Lúpus Eritematoso Sistêmico; Ferimentos e Lesões. ABSTRACTThe aim is to describe the clinical case of a patient with Toxic Epidermal Necrolysis focusing on the evolution ofcutaneous lesions; to discuss the disease progression and the use of covers available for the curative; and to analyzethe effectiveness of the treatment employed with Polihexanide Betaine Solution (PHMB) and Hydrofiber plates withSilver. This is a case report held in a federal hospital in the state of Rio de Janeiro. The patient in question authorizedthis report through The Free Informed Consent Form, according to Resolution 466/12. The curative was performeddaily, in the Surgical Center by the Therapeutic Committee of Wounds (TCW) and Medical Plastic Surgery. In thebody curative, which presented areas with complete detachment of the epidermis initially friable was performedprimary cover with Silver Sulfadiazine 1% cream. This conduct was maintained for 07 days. There was no apparentimprovement. Then antisepsis was performed with PHMB and was used plates throughout the body. After 15 days,in the third dressing exchange, a significant improvement was evidenced, not requiring the use of Hydrofiber. Itconcludes that the efficacy of the treatment used was clear and it is evident the importance of using the appropriatecoverage for each demand, being advantageous and beneficial to the patient, the teams involved and the institution.Keywords: Autoimmune Diseases; Lupus Erythematosus, Systemic; Wounds and Injuries.

2020 ◽  
Vol 16 (3) ◽  
pp. 320-324
Author(s):  
Lesya Besh ◽  
◽  
Oksana Matsyura ◽  
Olesya Besh ◽  
Olga Troyanovska ◽  
...  

Eczema herpeticum is a chronic dermatosis with erosive and ulcerative lesions of the skin in children of a predominantly young age. The clinical case presented in this article shows the severe course of herpesvirus infection combined with atopic dermatitis in a 5-month infant. A rash in the form of vesicles and pustules throughout the body with a predominant localisation on the skin of the face, the scalp, neck, and chest was found in the course of the examination of the child. Influence of infections on the course of allergic processes is an ambiguous and complicated issue. It has been proved that an infection can contribute to the development of allergies and exacerbate the course of already existing allergic inflammation. In recent years, an increasing number of studies have shown the preventive effect of infection on the development of allergic pathology in children, especially during the first years of life.


Author(s):  
Meghana Devulapallli ◽  
T. S. Durga Prasad ◽  
G. V. Narasimha Kumar ◽  
B. Avanthi ◽  
S. K. Shabana Banu

Systemic lupus erythematosus (SLE) is a non-specific systemic inflammatory disease that affects various organ systems in the body leading to a wide spectrum of clinical presentations. The management of SLE includes therapy with immunosuppressant agents who have a narrow safety range and a wide adverse effect profile. Methotrexate discussed in this case report is one of such drugs whose short term and long term usage has been associated with various adverse events that affect the individuals quality of life. So, it is always advisable to take prophylactic measures and to provide patient education to detect and prevent adverse events at the earliest.


2020 ◽  
Vol 19 (3-4) ◽  
pp. 145-150
Author(s):  
Karolis Černauskis ◽  
Sandra Kružyk ◽  
Gabrielė Šukytė ◽  
Linas Venclauskas ◽  
Mantas Sakalauskas

Introduction. Liposuction is one of the most popular aesthetic surgical procedures. Liposuction is associated with weight loss, but the primary significance of this operation is body lines contouring. According to US plastic surgery statistics for 2018, liposuction surgery was ranked in the top five of cosmetic surgical procedures, and the most common area of suction in the body was the abdomen. One of the most difficult complications after this procedure is perforation of the small or large intestine, with a frequency of 0.014%. In order to avoid this complication, a comprehensive pre-operative, post-operative examination of the patient and ensuring the safety of the operation are important. We presenting a complicated clinical case of liposuction and literature review. Presentation of case report. In July 2019, a 49-year-old patient underwent surgery by plastic surgeons. Abdominal liposuction surgery was performed. On the first postoperative day, the patient complained of diffuse abdominal pain (VAS 7–8 points), but there were no clinical signs of peritonitis. The patient underwent urgent surgery following the development of a clinical picture of sepsis and peritonitis due to tomography. The operation started with diagnostic laparoscopy. On the left side of the abdominal wall, 4–5 mm abdominal wall defects were observed, and the intestinal cavity was rich in intestinal contents. No obvious injuries to the small intestine, colon or other abdominal organs were observed during laparoscopy. Therefore, a laparotomy was performed, during which two perforations of the small intestine were found and sutured. The postoperative period was smooth, with the patient discharged home after 11 bed days. Conclusions. Intestinal perforation after liposuction is a rare but dangerous complication. Although bowel injury is one of the most severe complications. Prevention is possible starting with a detailed clinical examination of the patient in the preoperative period. The postoperative period should be particularly important in light of the patient’s complaints and clinical symptoms. The presented clinical case shows what a complication of abdominal liposuction can be threatening and how important its early diagnosis and vigilance are.


PEDIATRICS ◽  
1982 ◽  
Vol 70 (2) ◽  
pp. 296-299
Author(s):  
Jahed A. Hamdan ◽  
Mohammed S. Ahmad ◽  
Abdel Rahman Sa'adi

Malacoplakia is a rare chronic inflammatory disease, usually involving the bladder but occasionally affecting other organs. However, only two cases of malacoplakia of the retroperitoneum and ureter have been reported in the English language literature.1,2 Herein, we describe the third case of malacoplakia of the retroperitoneum and ureter in a patient with systemic lupus erythematosus who had been receiving prednisone therapy for two years. Modification by the steroid of phagocytosis and of the normal inflammatory response to bacterial infection, and the systemic lupus erythematosus, may have been of major importance in the genesis of malacoplakia in this patient. CASE REPORT


2017 ◽  
Vol 95 (2) ◽  
pp. 168-172
Author(s):  
Mariya Z. Kanevskaya ◽  
O. M. Kuznetsova

We report a clinical case of SLE in a women affected at the age of 63 years who had recurrent nephrotic syndrome with the development of renal insufficiency at the onset and a good outcome of therapy with a large total dose cyclophosphamide.


2014 ◽  
Vol 45 (S 01) ◽  
Author(s):  
L. Voges ◽  
G. Stettner ◽  
D. Weise ◽  
K. Brockmann ◽  
J. Gärtner ◽  
...  

2006 ◽  
Vol 54 (1) ◽  
pp. 39
Author(s):  
Jun Hyun Yun ◽  
Hyun Jun Choi ◽  
Ji Hyeo Choi ◽  
Ju Hyun Im ◽  
Se Jong Kim ◽  
...  
Keyword(s):  

2019 ◽  
Vol 1 (9) ◽  
pp. 53-57
Author(s):  
T. N. Gavva ◽  
L. V. Kuzmenkova ◽  
Yu. N. Fedulaev ◽  
T. V. Pinchuk ◽  
D. D. Kaminer ◽  
...  

A case of lung damage in systemic lupus erythematosus (SLE) in a 33-year-old woman is described. This case is of clinical interest due to the complexity of diagnosis due to the fact that SLE is a disease with diverse clinical manifestations involving many organs and systems, which often makes it difficult to timely recognize the onset of the disease. SLE still remains a challenge and requires special attention to the patient s history, clinical and laboratory parameters of the patient, as well as specific immunological examinations.


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