scholarly journals The Relationship Between C Reactive Protein /Albumin Ratio And 1-Year Mortality In Hospitalized Elderly Copd Patients With Acute Exacerbation

2019 ◽  
Vol 22 (1) ◽  
pp. 9-17
Author(s):  
Bilge Kağan Tur
Keyword(s):  
Acute Exacerbation ◽  
C Reactive Protein ◽  
Albumin Ratio ◽  
Reactive Protein ◽  
Hospitalized Elderly ◽  
Copd Patients ◽  
The Relationship

Assessment of the Relationship Between C-Reactive Protein-to-Albumin Ratio and the Presence and Severity of Isolated Coronary Artery Ectasia

Angiology ◽  
2020 ◽  
Vol 71 (9) ◽  
pp. 840-846
Author(s):  
Seçkin Dereli ◽  
İdris Buğra Çerik ◽  
Ahmet Kaya ◽  
Osman Bektaş
Keyword(s):  
Coronary Artery ◽  
Characteristic Curve ◽  
Obstructive Coronary Artery Disease ◽  
Area Under The Curve ◽  
Coronary Artery Ectasia ◽  
C Reactive Protein ◽  
Albumin Ratio ◽  
Cholesterol Ratio ◽  
Reactive Protein ◽  
The Relationship

We investigated the relationship between C-reactive protein-to-albumin ratio (CAR) and coronary artery ectasia (CAE). The retrospective study population included 150 patients with isolated CAE, 150 with obstructive coronary artery disease (CAD), and 150 with a normal coronary artery angiogram (NCA). The severity of isolated CAE was determined according to the Markis classification. C-reactive protein-to-albumin ratio was significantly higher in patients with isolated CAE than in those with obstructive CAD and NCA (10.5 [5.9-30.9], 5.7 [1.8-13.2] and 3.0 [0.9-8.9], respectively). Logistic regression analysis showed that CAR (odds ratio [OR]: 3.054, 95% CI: 1.021-9.165, P = .001), platelet-to-lymphocyte ratio (PLR; OR: 1.330, 95% CI: 1.025-1.694, P = .044), and monocyte-to-high density cholesterol ratio (MHR; OR: 1.031, 95% CI: 1.009-1.054, P = .006) were independently associated with the presence of isolated CAE. Receiver operating characteristic curve analysis showed that CAR (area under the curve [AUC] ± standard error [SE] = 0.838 ± 0.016; P < .001) had a stronger diagnostic value for detecting significant CAE than PLR (AUC ± SE = 0.632 ± 0.023) and MHR (AUC ± SE = 0.726 ± 0.022). C-reactive protein-to-albumin ratio had a significantly strong correlation with the severity of isolated CAE (r = 0.536, P < .001). To the best of our knowledge, this study showed for the first time that CAR was significantly associated with CAE presence and severity.

scholarly journals C-Reactive Protein/Albumin and Neutrophil/Albumin Ratios as Novel Inflammatory Markers in Patients with Schizophrenia

2020 ◽  
Vol 17 (9) ◽  
pp. 902-910
Author(s):  
Yasin Hasan Balcioglu ◽  
Simge Seren Kirlioglu
Keyword(s):  
Acute Exacerbation ◽  
Inflammatory Markers ◽  
Healthy Subjects ◽  
C Reactive Protein ◽  
Characteristic Analysis ◽  
Distribution Width ◽  
Albumin Ratio ◽  
Lymphocyte Ratio ◽  
Reactive Protein ◽  
Inflammatory Status

Objective Peripheral biomarker studies in schizophrenia are insufficient to correspond to whether inflammatory markers are trait- or state-related. The main objective of this study was to compare novel biomarkers C-reactive protein/albumin ratio (CAR), neutrophil/albumin ratio (NAR), and complete blood count-derived inflammatory markers; neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), monocyte/lymphocyte ratio (MLR), red-cell distribution width (RDW), and mean platelet volume (MPV) between patients with acutely exacerbated and remitted schizophrenia and healthy controls.Methods Anonymous data of a total of 618 patients with schizophrenia (179 in remission, 439 with acute exacerbation) and 445 psychiatrically and medically healthy subjects admitted to outpatient units were included. One-way ANOVA with Tukey’s HSD post-hoc test, Pearson’s correlation test, receiver operating characteristic analysis, and binomial logistic regression analysis were performed.Results CAR, NAR, NLR, PLR, MLR, RDW, MPV values were found higher in patients with schizophrenia than in healthy subjects. Except for NAR (p=0.007), none of the markers differed between acute exacerbation and remission. As a cut-off value of CAR, 0.388 differentiated patients with schizophrenia from controls (sensitivity 81%, specificity 81%). CAR, NAR, and MPV significantly predicted the diagnosis of schizophrenia.Conclusion CAR and NAR are reliable biomarkers of inflammation and a combination of inflammatory markers including CAR and NAR could be used to reflect the increased inflammatory status in schizophrenia, regardless of relapse or remission.

scholarly journals High C-reactive protein/albumin ratio increased risk of acute malnutrition during hospitalization in pediatric patients

2020 ◽  
Vol 4 (3) ◽  
pp. 32-38
Author(s):  
I Gusti Lanang Sidiartha ◽  
Dyah Kanya Wati ◽  
Ida Bagus Subanada ◽  
I Gusti Ngurah Made Suwarba
Keyword(s):  
Pediatric Patients ◽  
Child Growth ◽  
Acute Malnutrition ◽  
Adjusted Relative Risk ◽  
C Reactive Protein ◽  
Albumin Ratio ◽  
Reactive Protein ◽  
Increased Risk ◽  
The Relationship ◽  
Child Growth Standard

Pediatric patients with malnutrition commonly have poor prognosis related to the inflammation and catabolism state. This study investigated the relationship between high C-Reactive Protein/Albumin ratio on admission with the risk of acute malnutrition during hospitalization in pediatric patients. A cohort study in patients aged 1 month to 18 years old who met the study criteria was done. On admission, the level of serum C-Reactive Protein and Albumin were measured and calculated the C-Reactive protein/Albumin ratio which was divided into the high and low ratio. Acute malnutrition was determined according to the weight-for-height or body mass index-for-age z-score less than 2 SD below the WHO Child Growth Standard median.  A total of 110 patients were analyzed, 50% male and the mean aged was 77.7 months. Patients with acute malnutrition on admission and discharge were 24.5% and 32.7%, respectively. Acute malnutrition on discharge in patients with high and low ratio were 51.6% and 25.3%, respectively (adjusted Relative Risk, 9.1; 95% CI: 1. 9 to 42.7; p = 0.005). High C-Reactive Protein/Albumin ratio on admission increased the risk of acute malnutrition during hospitalization in pediatric patients.

scholarly journals Predictive values of biochemical markers as early indicators for severe COVID-19 cases in admission

2021 ◽  
Author(s):  
Emin Gemcioglu ◽  
Mehmet Davutoglu ◽  
Ramis Catalbas ◽  
Berkan Karabuga ◽  
Enes Kaptan ◽  
...  
Keyword(s):  
Biochemical Markers ◽  
Severe Disease ◽  
High Morbidity ◽  
C Reactive Protein ◽  
Prognostic Information ◽  
Protein Ratio ◽  
Predictive Values ◽  
Albumin Ratio ◽  
Reactive Protein ◽  
The Relationship

Aim: COVID-19 is a pandemic that causes high morbidity and mortality, especially in severe patients. In this study, we aimed to search and explain the relationship between biochemical markers, which are more common, easily available and applicable to diagnose and to stage the disease. Materials & methods: In this study, 609 patients were evaluated retrospectively. 11 biochemical parameters were included in analysis to explain the relationship with severity of disease. Results: Nearly, all the parameters that have been evaluated in this study were statistically valuable as a predictive parameter for severe disease. Areas under the curve of blood urea nitrogen (BUN)/albumin ratio (BAR), CALL score and lymphocyte/C-reactive protein ratio were 0.795, 0.778 and 0.770. The BUN/BAR and neutrophil/albumin ratios provide important prognostic information for decision-making in severe patients with COVID-19. Conclusion: High BUN/BAR and neutrophil/albumin ratios may be a better predictor of severity COVID-19 than other routinely used parameters in admission.

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