scholarly journals Evaluation of the relationship between C-Reactive Protein/Albumin Ratio and Hospitalization in Novel Coronavirus disease-19 (COVID-19)

2021 ◽  
Author(s):  
çiğdem damla deniz
Keyword(s):  
C Reactive Protein ◽  
Albumin Ratio ◽  
Reactive Protein ◽  
Novel Coronavirus ◽  
The Relationship

Assessment of the Relationship Between C-Reactive Protein-to-Albumin Ratio and the Presence and Severity of Isolated Coronary Artery Ectasia

Angiology ◽  
2020 ◽  
Vol 71 (9) ◽  
pp. 840-846
Author(s):  
Seçkin Dereli ◽  
İdris Buğra Çerik ◽  
Ahmet Kaya ◽  
Osman Bektaş
Keyword(s):  
Coronary Artery ◽  
Characteristic Curve ◽  
Obstructive Coronary Artery Disease ◽  
Area Under The Curve ◽  
Coronary Artery Ectasia ◽  
C Reactive Protein ◽  
Albumin Ratio ◽  
Cholesterol Ratio ◽  
Reactive Protein ◽  
The Relationship

We investigated the relationship between C-reactive protein-to-albumin ratio (CAR) and coronary artery ectasia (CAE). The retrospective study population included 150 patients with isolated CAE, 150 with obstructive coronary artery disease (CAD), and 150 with a normal coronary artery angiogram (NCA). The severity of isolated CAE was determined according to the Markis classification. C-reactive protein-to-albumin ratio was significantly higher in patients with isolated CAE than in those with obstructive CAD and NCA (10.5 [5.9-30.9], 5.7 [1.8-13.2] and 3.0 [0.9-8.9], respectively). Logistic regression analysis showed that CAR (odds ratio [OR]: 3.054, 95% CI: 1.021-9.165, P = .001), platelet-to-lymphocyte ratio (PLR; OR: 1.330, 95% CI: 1.025-1.694, P = .044), and monocyte-to-high density cholesterol ratio (MHR; OR: 1.031, 95% CI: 1.009-1.054, P = .006) were independently associated with the presence of isolated CAE. Receiver operating characteristic curve analysis showed that CAR (area under the curve [AUC] ± standard error [SE] = 0.838 ± 0.016; P < .001) had a stronger diagnostic value for detecting significant CAE than PLR (AUC ± SE = 0.632 ± 0.023) and MHR (AUC ± SE = 0.726 ± 0.022). C-reactive protein-to-albumin ratio had a significantly strong correlation with the severity of isolated CAE (r = 0.536, P < .001). To the best of our knowledge, this study showed for the first time that CAR was significantly associated with CAE presence and severity.

scholarly journals High C-reactive protein/albumin ratio increased risk of acute malnutrition during hospitalization in pediatric patients

2020 ◽  
Vol 4 (3) ◽  
pp. 32-38
Author(s):  
I Gusti Lanang Sidiartha ◽  
Dyah Kanya Wati ◽  
Ida Bagus Subanada ◽  
I Gusti Ngurah Made Suwarba
Keyword(s):  
Pediatric Patients ◽  
Child Growth ◽  
Acute Malnutrition ◽  
Adjusted Relative Risk ◽  
C Reactive Protein ◽  
Albumin Ratio ◽  
Reactive Protein ◽  
Increased Risk ◽  
The Relationship ◽  
Child Growth Standard

Pediatric patients with malnutrition commonly have poor prognosis related to the inflammation and catabolism state. This study investigated the relationship between high C-Reactive Protein/Albumin ratio on admission with the risk of acute malnutrition during hospitalization in pediatric patients. A cohort study in patients aged 1 month to 18 years old who met the study criteria was done. On admission, the level of serum C-Reactive Protein and Albumin were measured and calculated the C-Reactive protein/Albumin ratio which was divided into the high and low ratio. Acute malnutrition was determined according to the weight-for-height or body mass index-for-age z-score less than 2 SD below the WHO Child Growth Standard median.  A total of 110 patients were analyzed, 50% male and the mean aged was 77.7 months. Patients with acute malnutrition on admission and discharge were 24.5% and 32.7%, respectively. Acute malnutrition on discharge in patients with high and low ratio were 51.6% and 25.3%, respectively (adjusted Relative Risk, 9.1; 95% CI: 1. 9 to 42.7; p = 0.005). High C-Reactive Protein/Albumin ratio on admission increased the risk of acute malnutrition during hospitalization in pediatric patients.

An increased pretreatment C-reactive protein-to-albumin ratio predicts severe novel coronavirus-infected pneumonia

2020 ◽  
Author(s):  
Xiaoyue Wang ◽  
Yan Xu ◽  
Huang Huang ◽  
Desheng Jiang ◽  
Chunlei Zhou ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Early Warning ◽  
Multivariate Logistic Regression Analysis ◽  
Warning Signs ◽  
C Reactive Protein ◽  
Albumin Ratio ◽  
Reactive Protein ◽  
Novel Coronavirus

Abstract Objective The aim of this study was to identify early warning signs for severe novel coronavirus-infected pneumonia (COVID-19). Methods We retrospectively analyzed the clinical data of 90 patients with COVID-19 from Guanggu District of Hubei Women and Children Medical and Healthcare Center comprising 60 mild cases and 30 severe cases. The demographic data, underlying diseases, clinical manifestations and laboratory blood test results were compared between the two groups. The cutoff values was determined by receiver operating characteristic curve analysis. Logistic regression analysis was performed to identify the independent risk factor that predicted the severe COVID-19. Results The patients with mild and severe COVID-19 showed significant differences in terms of cancer incidence, age, pretreatment neutrophil-to-lymphocyte ratio (NLR), and pretreatment C-reactive protein-to-albumin ratio (CAR) (P < 0.05). The severity of COVID-19 was correlated positively with the comorbidity of cancer, age, NLR, and CAR (P < 0.05). Multivariate logistic regression analysis showed that age, NLR and CAR were independent risk factors for severe COVID-19 (OR = 1.086, P = 0.008; OR = 1.512, P = 0.007; OR = 17.652, P = 0.001, respectively). Conclusion An increased CAR can serve as an early warning sign of severe COVID-19 in conjunction with the NLR and age.

scholarly journals Predictive values of biochemical markers as early indicators for severe COVID-19 cases in admission

2021 ◽  
Author(s):  
Emin Gemcioglu ◽  
Mehmet Davutoglu ◽  
Ramis Catalbas ◽  
Berkan Karabuga ◽  
Enes Kaptan ◽  
...  
Keyword(s):  
Biochemical Markers ◽  
Severe Disease ◽  
High Morbidity ◽  
C Reactive Protein ◽  
Prognostic Information ◽  
Protein Ratio ◽  
Predictive Values ◽  
Albumin Ratio ◽  
Reactive Protein ◽  
The Relationship

Aim: COVID-19 is a pandemic that causes high morbidity and mortality, especially in severe patients. In this study, we aimed to search and explain the relationship between biochemical markers, which are more common, easily available and applicable to diagnose and to stage the disease. Materials & methods: In this study, 609 patients were evaluated retrospectively. 11 biochemical parameters were included in analysis to explain the relationship with severity of disease. Results: Nearly, all the parameters that have been evaluated in this study were statistically valuable as a predictive parameter for severe disease. Areas under the curve of blood urea nitrogen (BUN)/albumin ratio (BAR), CALL score and lymphocyte/C-reactive protein ratio were 0.795, 0.778 and 0.770. The BUN/BAR and neutrophil/albumin ratios provide important prognostic information for decision-making in severe patients with COVID-19. Conclusion: High BUN/BAR and neutrophil/albumin ratios may be a better predictor of severity COVID-19 than other routinely used parameters in admission.

scholarly journals Clinical impact of C-reactive protein to albumin ratio of the 7th postoperative day on prognosis after laparoscopic colorectal cancer surgery

2022 ◽  
Author(s):  
Masahiro Kataoka ◽  
Kuniyuki Gomi ◽  
Ken Ichioka ◽  
Takuya Iguchi ◽  
Tomoki Shirota ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Prognostic Factor ◽  
Radical Resection ◽  
Significant Prognostic Factor ◽  
C Reactive Protein ◽  
Colorectal Cancer Surgery ◽  
Free Survival ◽  
Albumin Ratio ◽  
Reactive Protein ◽  
The Relationship

Abstract Background/Aim: C-reactive protein to albumin ratio (CAR) has been utilized as a prognostic factor in various carcinomas. We investigated the relationship between preoperative, first postoperative day (POD1), and seventh postoperative day (POD7) CARs and the prognosis of patients with colorectal cancer (CRC). Patients and Methods: 320 patients with CRC who underwent laparoscopic radical resection between May 2011 and December 2016 were enrolled. Patients were selected into two groups, high CAR and low CAR, based on preoperative, POD1, and POD7 CARs. The relapse-free survival (RFS) and overall survival (OS) were compared between groups using propensity score matching. Results The high CAR group had a significantly worse RFS and OS (n=72/group, RFS: p<0.001; OS: p=0.002) at POD7 than those in the low CAR group. However, in preoperative and POD1 analysis, no differences were observed. Conclusion In patients with colorectal cancer, CAR of POD7 was a significant prognostic factor.

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