Is dental caries experience increased in HIV-infected children and adolescents? A meta-analysis

2015 ◽  
Vol 73 (7) ◽  
pp. 481-487 ◽  
Author(s):  
Cristiana Aroeira Guimarães Rosa Oliveira ◽  
Patricia Nivoloni Tannure ◽  
Ivete Pomarico Ribeiro de Souza ◽  
Lucianne Cople Maia ◽  
Maristela Barbosa Portela ◽  
...  
Keyword(s):  
Dental Caries ◽  
Children And Adolescents ◽  
Meta Analysis ◽  
Caries Experience

Does non-institutionalized elders have a better oral health status compared to institutionalized ones? A systematic review and meta-analysis

2020 ◽  
Vol 25 (6) ◽  
pp. 2177-2192 ◽  
Author(s):  
Ilky Pollansky Silva e Farias ◽  
Simone Alves de Sousa ◽  
Leopoldina de Fátima Dantas de Almeida ◽  
Bianca Marques Santiago ◽  
Antonio Carlos Pereira ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Status ◽  
Oral Health ◽  
Dental Caries ◽  
Meta Analysis ◽  
Oral Health Status ◽  
Cochrane Library ◽  
Caries Experience ◽  
Institutionalized Elderly ◽  
Periodontal Status

Abstract This systematic review compared the oral health status between institutionalized and non-institutionalized elders. The following electronic databases were searched: PubMed (Medline), Scopus, Web of Science, Lilacs and Cochrane Library, in a comprehensive and unrestricted manner. Electronic searches retrieved 1687 articles, which were analyzed with regards to respective eligibility criteria. After reading titles and abstracts, five studies were included and analyzed with respect their methodological quality. Oral status of institutionalized and non-institutionalized elderly was compared through meta-analysis. Included articles involved a cross-sectional design, which investigated 1936 individuals aged 60 years and over, being 999 Institutionalized and 937 non-institutionalized elders. Studies have investigated the prevalence of edentulous individuals, the dental caries experience and the periodontal status. Meta-analysis revealed that institutionalized elderly have greater prevalence of edentulous (OR = 2.28, 95%CI = 1.68-3.07) and higher number of decayed teeth (MD = 0.88, 95%CI = 0.71-1.05) and missed teeth (MD = 4.58, 95%CI = 1.89-7.27). Poor periodontal status did not differ significantly between groups. Compared to non-institutionalized, institutionalized elders have worse dental caries experience.

scholarly journals Prevalence of dental caries in children and adolescents with type 1 diabetes: a systematic review and meta-analysis

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Yan Wang ◽  
Lin Xing ◽  
Hui Yu ◽  
LiJuan Zhao
Keyword(s):  
Type 1 Diabetes ◽  
Dental Caries ◽  
Children And Adolescents ◽  
Metabolic Control ◽  
Meta Analysis ◽  
Preventive Treatment ◽  
Diabetic Patients ◽  
China National Knowledge Infrastructure ◽  
Pooled Prevalence

Abstract Background Dental caries and type 1 diabetes are responsible for a large burden of global disease; however, the exact prevalence of dental caries among children and adolescents with type 1 diabetes remains controversial, and no quantitative meta-analysis exists. Thus, we performed a meta-analysis to evaluate the prevalence of dental caries among children and adolescents with type 1 diabetes. Methods We performed a systematic search strategy using PubMed, EMBASE and China National Knowledge Infrastructure for relevant studies investigating the prevalence of dental caries in children and adolescents with type 1 diabetes from July 1971 until December 2018. The pooled prevalence with 95% confidence intervals (95%CIs) and subgroup analyses were calculated using a random effects model. Results After screening 358 non-duplicated articles, a total of 10 articles involving 538 individuals were included. The overall prevalence of dental caries among children and adolescents with type 1 diabetes was 67% (95% CI: 0.56–0.77%; I2 = 83%). The prevalence was highest in South America (84%) and lowest in diabetic patients with good metabolic control (47%). Conclusions The prevalence of dental caries was high among children and adolescents with type 1 diabetes. Screening and preventive treatment should be included in dental clinical routines for diabetic children and adolescents, especially in those with poor metabolic control.

MMP20 rs1784418 Protects Certain Populations against Caries

2016 ◽  
Vol 51 (1) ◽  
pp. 46-51 ◽  
Author(s):  
Arnôldo V.A. Filho ◽  
Merilene S. Calixto ◽  
Kathleen Deeley ◽  
Neide Santos ◽  
Aronita Rosenblatt ◽  
...  
Keyword(s):  
Risk Factor ◽  
Dental Caries ◽  
Dna Extraction ◽  
Meta Analysis ◽  
Primary Dentition ◽  
Analytic Approach ◽  
Caries Experience ◽  
Statistical Approaches

This work aimed to further evaluate the association of MMP20 rs1784418 C>T and dental caries experience with the hypothesis that MMP20 rs1784418 C>T is a risk factor for dental caries. 184 children 4-7 years of age had their caries experience determined and buccal cheek swabs collected for DNA extraction to test for association with the MMP20 rs1784418 C>T using standard statistical approaches. A meta-analytic approach was also implemented to compile previous discrepant reports of the same association. We found an association between MMP20 rs1784418 C>T and dental caries experience in primary dentition (p = 0.01). The meta-analysis showed that this association appears to favor individuals born in Brazil and not Turkey. MMP20 rs1784418 C>T appears to protect against dental caries, but its effects are likely to be more marked in certain populations.

scholarly journals Dental caries experience among indigenous children and adolescents

2015 ◽  
Vol 57 (2) ◽  
pp. 123-129 ◽  
Author(s):  
Érica M. Gonçalves ◽  
Laysa C. Cavalcanti ◽  
Ramon T. Firmino ◽  
Gustavo L. Ribeiro ◽  
Ana F. Granville-Garcia ◽  
...  
Keyword(s):  
Dental Caries ◽  
Children And Adolescents ◽  
Caries Experience ◽  
Indigenous Children

Multiple Socioeconomic Factors and Dental Caries in Swedish Children and Adolescents

2017 ◽  
Vol 52 (1-2) ◽  
pp. 42-50 ◽  
Author(s):  
Ann-Catrin André Kramer ◽  
Max Petzold ◽  
Magnus Hakeberg ◽  
Anna-Lena Östberg
Keyword(s):  
Dental Caries ◽  
Socioeconomic Factors ◽  
Children And Adolescents ◽  
Parental Education ◽  
Principal Component ◽  
Caries Experience ◽  
Older Children ◽  
Crude Odds Ratio ◽  
Education And Employment ◽  
Electronic Dental Records

The study aimed to explore associations between multiple socioeconomic factors and dental caries experience in Swedish children and adolescents (3-19 years old). Electronic dental records from 300,988, in a Swedish region (97.3% coverage) were collected using the DMFT indices (decayed, missing, filled teeth: dependent variables). Socioeconomic status (SES) data (ethnicity, wealth, parental education, and employment) for individuals, parents, and families were obtained from official registers. Principal component analysis was used to explore SES data. Scores based on the first factor were used as an independent aggregated socioeconomic variable in logistic regression analyses. Dental caries experience was low in the participants: 16% in 3- to 6-year-olds (deft index: decayed, extracted, filled teeth) and 47% in 7- to 19-year-olds (DFT index). Both separate and aggregated socioeconomic variables were consistently associated with the dental caries experience irrespective of the caries index used: the crude odds ratio (OR) for having at least 1 caries lesion in 3- to 6-year-olds (deft index) in the lowest SES quintile was 3.26 (95% confidence interval [CI] 3.09-3.43) and in ≥7-year-olds (DFT index) OR 1.80 (95% CI 1.75-1.84) compared with children in the 4 higher SES quintiles. Overall, associations were stronger in the primary dentition than in the permanent dentition. Large SES models contributed more to explaining the caries experience than slim models including fewer SES indicators. In conclusion, socioeconomic factors were consistently associated with dental caries experience in the children and adolescents both as single factors and as multiple factors combined in an index. Socioeconomic inequalities had stronger associations to caries experience in young children than in older children and adolescents.

scholarly journals Genetic Association ofMMP10,MMP14, andMMP16with Dental Caries

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
D. D. Lewis ◽  
J. R. Shaffer ◽  
E. Feingold ◽  
M. Cooper ◽  
M. M. Vanyukov ◽  
...  
Keyword(s):  
Dental Caries ◽  
Genome Wide Association Study ◽  
Meta Analysis ◽  
Extracellular Proteins ◽  
Caries Experience ◽  
Caries Risk ◽  
Physiological Processes ◽  
Genome Wide ◽  
A Genome ◽  
White Adults

Matrix metalloproteinases (MMPs), which degrade extracellular proteins as part of a variety of physiological processes, and their inhibitors have been implicated in the dental caries process. Here we investigated 28 genetic variants spanning theMMP10,MMP14, andMMP16genes to detect association with dental caries experience in 13 age- and race-stratified (n=3,587) samples from 6 parent studies. Analyses were performed separately for each sample, and results were combined across samples by meta-analysis. Two SNPs (rs2046315 and rs10429371) upstream ofMMP16were significantly associated with caries in an individual sample of white adults and via meta-analysis across 8 adult samples after gene-wise adjustment for multiple comparisons. Noteworthy is SNP rs2046315 (p=8.14×10-8) association with caries in white adults. This SNP was originally nominated in a genome-wide-association study (GWAS) of dental caries in a sample of white adults and yielded associations in a subsequent GWAS of surface level caries in white adults as well. Therefore, in our study, we were able to recapture the association between rs2046315 and dental caries in white adults. Although we did not strengthen evidence thatMMPs 10,14, and16influence caries risk,MMP16is still a likely candidate gene to pursue.

Caries experience in children and adolescents with Down Syndrome: A systematic review and meta-analysis

2020 ◽  
Vol 115 ◽  
pp. 104715
Author(s):  
Mabel Cristina Paiva Machado da Silva ◽  
Maria Carlla Aroucha Lyra ◽  
Híttalo Carlos Rodrigues de Almeida ◽  
Arnoldo Vasconcelos de Alencar Filho ◽  
Monica Vilela Heimer ◽  
...  
Keyword(s):  
Systematic Review ◽  
Down Syndrome ◽  
Children And Adolescents ◽  
Meta Analysis ◽  
Caries Experience
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