Click-Evoked Oto-Acoustic Emissions in Very-Low-Birth-Weight Infants: A Cross-Sectional Data Analysis

BACKGROUND: Very low birth weight infants born prematurely are at greater risk for growth delays that lead to Ex-utero Growth Restriction (EUGR) during vulnerable periods of organ structural and functional development. There is considerable evidence that early growth failure has adverse effects on long term neurodevelopment in children which often persists into adulthood. METHODS: This is a single-center cross-sectional study on live newborn infants with birth weight ranges from 500 to 1500 grams (VLBW) and gestational age (GA) between 24–32 weeks who were admitted to NICU at KAMC-Jeddah over a 5 year period (2009–2013). This study aims to evaluate predischarge growth pattern of VLBW infants in terms of weight, head circumference (HC) and length and to identify important variables that have influenced such growth pattern. RESULTS: Of the 135 infants included in the final analysis, 68 (50.4%) were male and 67 (49.6%) were female and the mean gestational age was 28.83±2.064 weeks and the mean birth weight 1166.74±256 grams. Ninety-two infants (68%) had discharge weight at ≤10th percentile and forty four (32%) had their weight >10th percentile. HC was the lowest affected among the anthropometric measurements with 42% ≤10th percentile. In terms of linear growth, 62% had their length ≤10th percentile. Amongst infants born ≤750 grams, 71% and 70% had HC and height at ≤10th percentile respectively, at the time of discharge. BPD was significantly associated with EUGR (p = 0.026). CONCLUSIONS: This study demonstrates that almost 2/3rd of VLBW infants born at KAMC-Jeddah with birth weight ≤750 grams were discharged home with EUGR as demonstrated by their weight, length, and HC ≤10th percentile. BPD was found to be significantly associated with EUGR amongst post-natal factors influencing EUGR.

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Associated Factors to Immunization Timeliness and Completion in Preterm and Low Birth Weight Infants at Essos Hospital Center Yaounde

10.21203/rs.3.rs-110589/v1 ◽

2020 ◽

Author(s):

Marie Kouya ◽

Annie Carole Nga Motaze ◽

Jeannette Epee Ngoué ◽

Arsene Brunelle Sandie ◽

Paul Olivier Koki Ndombo ◽

...

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Very Low Birth Weight ◽

High Rate ◽

Routine Immunization ◽

Low Birth Weight Infants ◽

Cross Sectional ◽

Immunization Practice ◽

The Mean ◽

Hospital Center

Abstract Introduction. Vaccination is very often delayed in premature and low birth weight infants. However, timely vaccination is even more important in the latter because of their increased susceptibility to infection.Objective. To assess immunization practice and factors associated with vaccine promptness and completeness in former preterm and low-birth-weight infants.Methods. We conducted a retrospective analytical cross-sectional study (January 2017 to February 2019). Main measurement : Promptness and completeness at each contact, Statistical analysis was performed using R software version 3.6.2, logistic regression was used to estimate the Odds Ratio (OR) and their 95% Confidence Interval (CI).Results. We recruited 310 children aged 12 to 36 months born before 37 weeks with low birth weight, 163 (52.6%) of whom were female. Two hundred and fifty-three had received the vaccines at the indicated age, with promptness rate of 81.6%, and 97.7% had completed routine immunization at 9 months. The mean age at vaccination initiation was 6 days ±11 and the mean weight at vaccination initiation was 2233g ±494. High prematurity and very low birth weight were associated with a high rate of vaccine delay: 61.5% [OR: 15.56; (CI: 3.22-118.52; p=0.002)] and 66.7% [OR: 19.19; (CI: 4.67-92.52; p<0.001)] respectively. Distance > 5 km with HEC [OR: 3.48; (CI: 1.68-7.47; p=0.001)] was associated with poor vaccination. Women in common-law unions had the lowest vaccine readiness rate (60.6%), (OR: 3.36; CI: 1.006-10.70; p=0.038). The frequency of occurrence of post immunization adverse events was 24.5%, with fever type in 94.7%.Conclusion. Nearly all premature and/or low-birth-weight children hospitalized at Essos Hospital Center had completed routine immunization at 9 months, and the majority had received the vaccines in a timely manner. Similar study is needed in rural area.

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Z-score differences based on cross-sectional growth charts do not reflect the growth rate of very low birth weight infants

PLoS ONE ◽

10.1371/journal.pone.0216048 ◽

2019 ◽

Vol 14 (5) ◽

pp. e0216048 ◽

Cited By ~ 5

Author(s):

Niels Rochow ◽

Erin Landau-Crangle ◽

Hon Yiu So ◽

Anna Pelc ◽

Gerhard Fusch ◽

...

Keyword(s):

Growth Rate ◽

Birth Weight ◽

Low Birth Weight ◽

Very Low Birth Weight ◽

Growth Charts ◽

Z Score ◽

Low Birth Weight Infants ◽

Cross Sectional

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Weight-Based Policy of Hepatitis B Vaccination in Very Low Birth Weight Infants in Taiwan: A Retrospective Cross-Sectional Study

PLoS ONE ◽

10.1371/journal.pone.0092271 ◽

2014 ◽

Vol 9 (3) ◽

pp. e92271 ◽

Cited By ~ 5

Author(s):

Chien-Yi Chen ◽

Huey-Ling Chen ◽

Hung-Chieh Chou ◽

Po-Nien Tsao ◽

Wu-Shiun Hsieh ◽

...

Keyword(s):

Birth Weight ◽

Hepatitis B ◽

Low Birth Weight ◽

Very Low Birth Weight ◽

Cross Sectional Study ◽

Hepatitis B Vaccination ◽

Sectional Study ◽

Low Birth Weight Infants ◽

Cross Sectional

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Extrauterine Growth Restriction in Very Low Birth Weight Infants: Concordance Between Fenton 2013 and INTERGROWTH-21st Growth Charts

Frontiers in Pediatrics ◽

10.3389/fped.2021.690788 ◽

2021 ◽

Vol 9 ◽

Author(s):

Lara González-García ◽

Enrique García-López ◽

Belén Fernández-Colomer ◽

Laura Mantecón-Fernández ◽

Sonia Lareu-Vidal ◽

...

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Very Low Birth Weight ◽

Neonatal Morbidity ◽

Growth Restriction ◽

University Hospital ◽

Preterm Neonates ◽

Low Birth Weight Infants ◽

Cross Sectional ◽

Extrauterine Growth Restriction

Postnatal growth restriction has high prevalence in very low birth weight (VLBW) preterm neonates, and this could affect their long-term prognosis. Nowadays, there is no consensus on how to monitor growth in these neonates.Objective: This study aimed to compare prevalence of intra- and extrauterine growth restriction (IUGR and EUGR) in a sample of VLBW infants according to the Fenton 2013 charts and INTERGROWTH-21st (IW-21) standards and to analyze concordance between both in the different EUGR definitions criteria (cross-sectional, dynamic, and true).Patients and Methods: An observational retrospective study of 635 VLBW preterm was performed. The study was carried out in Central University Hospital of Asturias. Body measurements (weight, length, and head circumference) were collected at birth and at hospital discharge and expressed in z-scores for the two references (Fenton 2010 and IW-21). Kappa concordance was calculated.Results: Kappa concordance between Fenton and IW-21 was 0.887 for IUGR and 0.580 for static EUGR. Prevalence was higher according to Fenton in IUGR (36.5 vs. 35.1%), in static EUGR (73.8 vs. 59.3%), and in dynamic EUGR (44.3 vs. 29.3%). Despite observing low prevalence of EUGR when IW-21 was used to define EUGR, a statistical association between neonatal morbidity and diagnosis of EUGR was observed.Conclusion: The Fenton and IW-21 concordance for IUGR is good. IW-21 is more restrictive than Fenton in EUGR. Patients diagnosed by IW-21 as EUGR are more likely to have neonatal morbidity, especially if we use EUGR dynamic definition. In our study, we cannot conclude that one graph is better than the other.

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Teamwork in the NICU Setting and Its Association with Health Care–Associated Infections in Very Low-Birth-Weight Infants

American Journal of Perinatology ◽

10.1055/s-0037-1601563 ◽

2017 ◽

Vol 34 (10) ◽

pp. 1032-1040 ◽

Cited By ~ 8

Author(s):

Paul Sharek ◽

Peiyi Kan ◽

Joseph Rigdon ◽

Manisha Desai ◽

Courtney Nisbet ◽

...

Keyword(s):

Health Care ◽

Birth Weight ◽

Low Birth Weight ◽

Neonatal Intensive Care ◽

Very Low Birth Weight ◽

Clinical Care ◽

Random Effect ◽

Low Birth Weight Infants ◽

Cross Sectional ◽

Vlbw Infants

Background and Objective Teamwork may affect clinical care in the neonatal intensive care unit (NICU) setting. The objective of this study was to assess teamwork climate across NICUs and to test scale-level and item-level associations with health care–associated infection (HAI) rates in very low-birth-weight (VLBW) infants. Methods Cross-sectional study of the association between HAI rates, defined as any bacterial or fungal infection during the birth hospitalization, among 6,663 VLBW infants cared for in 44 NICUs between 2010 and 2012. NICU HAI rates were correlated with teamwork climate ratings obtained in 2011 from 2,073 of 3,294 eligible NICU health professionals (response rate 63%). The relation between HAI rates and NICU teamwork climate was assessed using logistic regression models including NICU as a random effect. Results Across NICUs, 36 to 100% (mean 66%) of respondents reported good teamwork. HAI rates were significantly and independently associated with teamwork climate (odds ratio, 0.82; 95% confidence interval, 0.73–0.92, p = 0.005), such that the odds of an infant contracting a HAI decreased by 18% with each 10% rise in NICU respondents reporting good teamwork. Conclusion Improving teamwork may be an important element in infection control efforts.

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