scholarly journals A new approach to investigating shipwreck sites in littoral envirornments: Multi-technique geophysical investigations of Port Elliot, South Australia

2021 ◽  
Author(s):  
Ian Moffat ◽  
Jason Raupp
Keyword(s):  
Survey Methodology ◽  
South Australia ◽  
Archaeological Sites ◽  
Second Phase ◽  
Limited Time ◽  
New Approach ◽  
Precise Information ◽  
Comprehensive Information ◽  
Geophysical Investigations

A bipartite geophysical survey methodology has been developed in order to locate archaeological sites in littoral environments and to gain precise information on their location, size and physical properties. The initial reconnaissance phase establishes the presence of prospective anomalies with limited time and budget. The second phase provides comprehensive information on the anomaly as context for further investigation if necessary. This approach was tested at Port Elliot, South Australia to locate the remains of the cutter Lapwing. An anomaly discovered during reconnaissance phase investigations proved inconsequential in phase two, and follow-up work was not carried out. This outcome demonstrates the benefits of using this approach in terms of money and time saved.

scholarly journals Geophysical investigations at the Anuru Bay trepang site: A new approach to locating Macassan archaeological sites in Northern Australia

2021 ◽  
Author(s):  
Jennifer McKinnon ◽  
Daryl Wesley ◽  
Jason Raupp ◽  
Ian Moffat
Keyword(s):  
Geophysical Survey ◽  
Archaeological Sites ◽  
Northern Australia ◽  
New Approach ◽  
System P ◽  
History Of ◽  
Geophysical Investigations ◽  
Processing Site ◽  
Opening Up ◽  
Archaeological Excavations

This paper presents the results of a magnetometer survey and initial archaeological excavations of Macassan and Indigenous features conducted at the Anuru Bay Macassan trepang processing site. The archaeology of this area is complex, containing both material reflecting the Indigenous utilisation of coastal resources and the periodic visits of the Macassan trepangers from Indonesia. Despite a history of archaeological investigations on Macassan period sites (i.e. Clarke 1994; McKnight 1976; Mitchell 1994), geophysical survey has not previously been applied as part of these investigations. While Macassan sites may contain features amenable to conventional archaeological geophysics (such as iron trepang processing pots), additional potential exists for the application of magnetometry to locate features created through burning, as has been applied to Australian Indigenous sites (Bonhomme & Stanley 1985; Fanning et al. 2009; Moffat et al. 2008 & 2010; Stanley & Green 1976; Wallis et al. 2008) and international Indigenous sites (Abbot & Frederick 1990; Batt & Dockrill 1998; Jones & Munson 2005). The results of this study demonstrate that this approach is equally applicable to Macassan sites, opening up a new and potentially fruitful avenue for exploring the archaeology of this trade system.

scholarly journals Long-Term Follow-Up of Giant Symptomatic Hepatic Hemangiomas Treated with Direct Sclerotherapy: Introducing a New Approach

2020 ◽  
Author(s):  
Hadi Rokni Yazdi ◽  
Niloofar Ayoobi Yazdi ◽  
Mohammad Mehdi Mehrabinejad ◽  
Habibollah Dashti ◽  
Morteza Ghassed ◽  
...  
Keyword(s):  
New Approach ◽  
Long Term Follow Up ◽  
Hepatic Hemangiomas

scholarly journals Innovative method for Amplatzer device implantation in patients with bronchopleural fistulas

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jisong Zhang ◽  
Huihui Hu ◽  
Li Xu ◽  
Shan Xu ◽  
Jihong Zhu ◽  
...  
Keyword(s):  
Present Report ◽  
Rare Complication ◽  
Bronchopleural Fistula ◽  
Rigid Bronchoscopy ◽  
New Approach ◽  
Device Implantation ◽  
Amplatzer Device ◽  
Field Of Vision ◽  
Duration Of Operation

Abstract Background Bronchopleural fistula (BPF) is a relatively rare complication after various types of pulmonary resection. The double-sided mushroom-shaped occluder (Amplatzer device, AD) has been gradually used for BPF blocking due to its reliable blocking effect. We have improved the existing AD implantation methods to facilitate clinical use and named the new approach Sheath-free method (SFM). The aim of the present report was to explore the reliability and advantages of the SFM in AD implantation. Methods We improved the existing implantation methods by abandoning the sheath of the AD and using the working channel of the bronchoscope to directly store or release the AD without general anesthesia, rigid bronchoscopy, fluoroscopy, or bronchography. A total of 6 patients (5 men and 1 woman, aged 66.67 ± 6.19 years [mean ± SD]) had BPF blocking and underwent the SFM in AD implantation. Results AD implantation was successfully performed in all 6 patients with the SFM, 4 persons had a successful closure of the fistula, one person died after few days and one person did not have a successful closure of the fistula. The average duration of operation was 16.17 min (16.17 ± 4.67 min [mean ± SD]). No patients died due to operation complications or BPF recurrence. The average follow-up time was 13.2 months (range 10–17 months). Conclusion We observed that the SFM for AD implantation—with accurate device positioning and a clear field of vision—is efficient and convenient. The AD is effective in BPF blocking, and could contribute to significantly improved symptoms of patients.

Strut remodeling with hypercompliant balloon: A new approach to Y stent-assisted coil embolization in the treatment of complex wide-neck bifurcation aneurysms

2020 ◽  
pp. 159101992098433
Author(s):  
Ali Burak Binboga ◽  
Mehmet Onay ◽  
Cetin Murat Altay
Keyword(s):  
Coil Embolization ◽  
Complication Rates ◽  
Thromboembolic Complications ◽  
New Approach ◽  
Long Term Follow Up ◽  
Safety Effectiveness ◽  
Wide Neck

Background The objective of this study was to present the long-term safety and effectiveness of strand remodelling with a hypercompliant balloon. Methods Patients with complex wide-neck bifurcation aneurysms (WNBAs) who underwent strand remodelling with a hypercompliant balloon via Y-stent-assisted coil embolization (Y-SACE) between September 2016 and January 2020 were included in the study. The feasibility, safety, effectiveness, and complication rates of the strand remodelling technique were investigated. Results A total of 12 patients (6 females, 6 males) were included in this study. Significant expansion was obtained in the intersection zone after remodelling. No regression was observed in the expansion rates during follow-up. There was no additional morbidity or mortality. No delayed thromboembolic complications occurred in our patients during long-term follow-up. Conclusions Performing strand remodelling to reduce thromboembolic complications triggered by structural faults caused by the Y-stent configuration is feasible, safe, and effective. This new approach can aid in the prevention of thromboembolic complications in Y-SACE.

scholarly journals Antigenic diversity and seroprevalences of Torque teno viruses in children and adults by ORF2-based immunoassays

2013 ◽  
Vol 94 (2) ◽  
pp. 409-417 ◽  
Author(s):  
Tingting Chen ◽  
Elina Väisänen ◽  
Petri S. Mattila ◽  
Klaus Hedman ◽  
Maria Söderlund-Venermo
Keyword(s):  
Serum Samples ◽  
Phylogenetic Groups ◽  
Single Strain ◽  
New Approach ◽  
Antiviral Antibody ◽  
Specific Igg ◽  
Species Specific ◽  
Multiple Strains ◽  
Antigenic Relationships

Torque teno viruses (TTVs) circulate widely among humans, causing persistent viraemia in healthy individuals. Numerous TTV isolates with high genetic variability have been identified and segregated into 29 species of five major phylogenetic groups. To date, the diversity of TTV sequences, challenges in protein expression and the subsequent lack of serological assays have hampered TTV seroprevalence studies. Moreover, the antigenic relationships of different TTVs and their specific seroprevalences in humans remain unknown. For five TTV strains – belonging to different species of four genogroups – we developed, using recombinant glutathione S-transferase (GST)-fused TTV ORF2 proteins, glutathione–GST capture enzyme immunoassays (EIAs) detecting antibodies towards conformational epitopes. We then analysed serum samples from 178 healthy adults and 108 children; IgG reactivities were observed either towards a single strain or towards multiple strains, which pointed to antigenic distinction of TTV species. The overall seroprevalence for the five TTVs peaked at 43 % (18 of 42) in children 2–4 years of age, subsequently declined, and again reached 42 % (74 of 178) among adults. TTV6 species-specific IgG predominated in children, whereas that for TTV13 predominated in adults. During a 3 year follow-up of the same children, both species-specific seroconversions and seroreversions occurred. This is the first EIA-based study of different TTVs, providing a new approach for seroepidemiology and diagnosis of TTV infections. Our data suggest that different TTVs in humans may differ in antiviral antibody profiles, infection patterns and epidemiology.

Abstract 77: Ongoing Leakage Revealed by Second Phase Spot Sign Volume Expansion in Multi-Phase Computed Tomography Angiography Strongly Predicts Intracranial Hemorrhage Growth

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Abdulaziz Al Sultan ◽  
Ericka Teleg ◽  
MacKenzie Horn ◽  
Piyush Ojha ◽  
Linda Kasickova ◽  
...  
Keyword(s):  
Volume Expansion ◽  
Single Phase ◽  
Meta Analysis ◽  
Hematoma Expansion ◽  
Second Phase ◽  
Hematoma Volume ◽  
Spot Sign ◽  
Time Resolved ◽  
Multi Phase

Background: CTA spot sign is a predictor of intracerebral hemorrhage (ICH) expansion. This sign can fluctuate in appearance, volume, and timing. Multiphase CTA (mCTA) can identify spot sign through 3 time-resolved images. We sought to identify a novel predictor of follow up total hematoma expansion using mCTA. Methods: This cohort study included patients with ICH between 2012-2019. Quantomo software was used to measure total hematoma volume (ml) from baseline CT & follow-up CT/MRI blinded to spot sign in 3 mCTA phases. Spot sign expansion was calculated by subtracting 1 st phase spot sign volume from 2 nd phase spot sign volume measured in microliters. Results: 199 patients [63% male, mean age 69 years, median NIHSS 11, IQR 6-20] were included. Median baseline ICH volume was 16.1 ml (IQR 5-29.9 ml). Amongst all three mCTA phases, spot sign was best detected on the 2nd phase (23% vs 17.5% 1 st phase vs 22% 3 rd phase). In multivariable regression, spot sign expansion was significantly associated with follow up total hematoma expansion (OR: 1.03 per microliter of spot sign expansion, p=0.01). Figure 1 shows the predicted total hematoma expansion by spot sign expansion. mCTA spot sign had a higher sensitivity for predicting total hematoma volume expansion than single-phase CTA (reported in meta-analysis of 14 studies), 86% vs 53%, respectively, while both having similar specificity, 87% vs 88%, respectively. Conclusion: Spot sign expansion on mCTA is a novel predictor of total hematoma expansion and could be used to select patients for immediate therapeutic intervention in future clinical trials. Using mCTA improves sensitivity while preserving specificity over single-phase CTA.

scholarly journals Community and heritage management: Linking stakeholders to archaeological sites in Kichakbadh

2019 ◽  
Vol 8 ◽  
pp. 107-116
Author(s):  
Abhijeet Thapa
Keyword(s):  
Human Activities ◽  
State Level ◽  
Heritage Management ◽  
The Other ◽  
Destination Image ◽  
Archaeological Sites ◽  
Second Phase ◽  
Heritage Sites ◽  
Multiple Field ◽  
Management Issues

Community has been much of a striking terminology these days when associated with heritage management. Communities living nearby heritage sites, while at one hand are agents of conservation, on the other hand are sources of destruction in heritage sites and agents of risks. As such, this research unfolds the contested roles of local people for taking ownership of heritage management, understanding heritages, transmitting oral intangible values and valuing destination image at Kichakbadh Province -1, Nepal. The research, aimed at studying heritage management issues around the site has been supplemented by multiple field visits, numerous questionnaires and interviews with locals, visitors and experts. This article chiefly deals with the second phase of author’s exploration carried out on an annual fair called Maghe Purnima at Kichakbadh in 2019. While science of archaeology restricts human activities in conserved places, large fairs are held in archaeologically sensitive areas of Kichakbadh posing threats to archeological wealth there. To utter dismay, archaeological crimes are still common in many sites at Kichakbadh. Multiple field-visits, questionnaire with the stakeholders, visitors and community during the fair reveal that minimal traces of community and state level endeavors to conserve the sites do not meet the vast rescue requirements that Kichakbadh is actually in need of.

scholarly journals Volunteering via Smart-Phone for People With Psychosis—Protocol of a Feasibility Trial

2021 ◽  
Vol 12 ◽  
Author(s):  
Mariana Pinto da Costa ◽  
Phone Pal Advisory Groups
Keyword(s):  
Smart Phone ◽  
Outcome Data ◽  
Text Messages ◽  
Feasibility Trial ◽  
Second Phase ◽  
Retention Data ◽  
The United Kingdom ◽  
Two Phases ◽  
Communication Methods

The literature suggests that volunteering can be used to address social isolation and support patients with psychosis in the community. However, many expect in person meetings, requiring a greater effort of availability and commitment. There is therefore a need for more flexible, easily accessible support. Volunteering via smart-phone could be a useful intervention for people with psychosis. One patient and one volunteer have been matched for a duration of 12 weeks, and participants have been encouraged to communicate through a variety of communication methods (audio calls, video calls, text messages, WhatsApp messages and e-mails). The Phone Pal study aimed to investigate the feasibility of recruitment, participant retention, data collection procedures, intervention usage of the methods of communication and changes in outcome data. At baseline and follow-up outcome measures collected from patients and volunteers included their quality of life, physical activity, self-esteem and social comparison. Additional outcomes assessed patients' attachment, social contacts and symptoms; for volunteers, their social distance was evaluated. At follow-up both patients and volunteers rank their perception of their relationship with each other. This mixed method feasibility study has been conducted in two phases, the first stage evaluating a smaller sample of patients and volunteers recruited in London, and then a second phase with a larger sample of volunteers recruited from across the United Kingdom.Trial registration: ISRCTN17586238.

Perspective From the American Academy of Pediatrics

PEDIATRICS ◽  
1989 ◽  
Vol 83 (5) ◽  
pp. 913-914
Author(s):  
Neil A. Holtzman
Keyword(s):  
Sickle Cell Disease ◽  
American Academy ◽  
Sickle Cell ◽  
Second Phase ◽  
Pilot Program ◽  
Cooperative Study ◽  
Cell Disease ◽  
Pilot Studies ◽  
American Academy Of Pediatrics

Ten years ago, the initial report of the Committee on Genetics of the American Academy of Pediatrics was published, drawing heavily on the landmark report published 2 years earlier by the National Academy of Sciences. That report stated that new mass screening tests should not be implemented without pilot studies or facilities for follow-up. I would like to deal with the efficacy of screening as determined by pilot studies, the effectiveness of routine screening, and the importance of follow-up. The Cooperative Study of Sickle Cell Disease was essentially the first phase of a large pilot program that systematically demonstrated that sepsis, meningitis, and acute splenic sequestration occurred in young infants with sickle cell disease. Previous reports suggested, and the cooperative study corroborated, that without prior diagnosis many of these infants would die. The randomized trial of oral penicillin prophylaxis was the second phase of the pilot program, demonstrating that early treatment significantly reduced mortality. Thus, the results of this pilot program, conducted with support of the National Institutes of Health, documented that newborn screening for sickle cell disease satisfied a major criterion for screening: An intervention capable of reducing mortality would be efficacious if applied before the usual age of clinical diagnosis. The pilot program was conducted under ideal conditions. The findings are not enough to conclude that screening for sickle cell disease and other hemoglobinopathies will always be effective when performed routinely.

A new approach to managing follow-up patients with sino-nasal disorders: the rhinology panel

2020 ◽  
Vol 26 (3) ◽  
pp. 88-93
Author(s):  
Abdulaziz Abushaala ◽  
Helen Sargent ◽  
Jennifer McLean ◽  
Deborah Grech-Marguerat ◽  
Hisham Khalil
Keyword(s):  
Patient Safety ◽  
Waiting List ◽  
Nurse Specialist ◽  
Review Panel ◽  
Clinical Nurse ◽  
New Approach ◽  
Specialist Registrar ◽  
Face To Face ◽  
Clinical Records

Background/aims There is a growing backlog of patients with sino-nasal disorders waiting for a follow-up appointment. This study aimed to identify rhinology patients on the outpatient follow-up list who could be removed from the waiting list for a face to face follow-up appointment and instead either given a phone consultation by a clinical nurse specialist or discharged from the service. Methods The clinical records of patients on the waiting list for a follow-up appointment at a nasal disorders clinic were reviewed by a panel comprising a consultant rhinologist, a rhinology fellow, a specialist registrar and two nurse specialists. Results A total of 300 clinical records of patients on the follow-up list of the Rhinology clinic were identified, of which 253 were found to have a sino-nasal disorder. Of these, 137 patients (54%) were discharged from the rhinology face to face follow-up clinics, while 116 patients (46%) were given face to face review appointments. Conclusions A multi-professional rhinology review panel is an effective way of managing the waiting list of an outpatient rhinology clinic and providing nurse-led telephone consultations could decrease the strain on resources while maintaining patient safety.

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